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2,833 results on '"Deubiquitinating enzyme"'

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1. Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells

2. The deubiquitinase OTUB1 fosters papillary thyroid carcinoma growth through EYA1 stabilization

3. Mutation of a Ubiquitin Carboxy Terminal Hydrolase L1 Lipid Binding Site Alleviates Cell Death, Axonal Injury, and Behavioral Deficits After Traumatic Brain Injury in Mice

4. Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis

5. USP21 prevents the generation of T-helper-1-like Treg cells

6. UbiBrowser 2.0: a comprehensive resource for proteome-wide known and predicted ubiquitin ligase/deubiquitinase–substrate interactions in eukaryotic species

7. USP35 mitigates endoplasmic reticulum stress‐induced apoptosis by stabilizing RRBP1 in non‐small cell lung cancer

8. Structure–Activity Relationship of USP5 Inhibitors

9. RNF126 is a positive regulator of TRAF3 ubiquitination

10. DDX3 interacts with USP9X and participates in deubiquitination of the anti‐apoptotic protein MCL1

11. USP21 Deubiquitinase Regulates AIM2 Inflammasome Activation

12. The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

13. USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer

14. Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke

15. TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination

16. The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

17. Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2

18. Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30

19. Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2

20. Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases

21. Estrogen prevents cellular senescence and bone loss through Usp10-dependent p53 degradation in osteocytes and osteoblasts: the role of estrogen in bone cell senescence

22. Small molecules as tools for functional assessment of deubiquitinating enzyme function

23. Deubiquitinating enzyme USP30 negatively regulates mitophagy and accelerates myocardial cell senescence through antagonism of Parkin

24. USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity

25. Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin

26. Real‐Time and Label‐Free Measurement of Deubiquitinase Activity with a MspA Nanopore

27. USP11 degrades KLF4 via its deubiquitinase activity in liver diseases

28. Inhibiting USP8 overcomes hepatocellular carcinoma resistance via suppressing receptor tyrosine kinases

29. Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression

30. Polycomb-group proteins in the initiation and progression of cancer

31. Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner

32. lncRNA TRMP-S directs dual mechanisms to regulate p27-mediated cellular senescence

33. The dystrophia myotonica WD repeat‐containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase

34. OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9

35. USP15: a review of its implication in immune and inflammatory processes and tumor progression

36. Transcriptional regulation of human abraxas brother protein 1 expression by yin yang 1

37. UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo

38. Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma

39. Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication

40. USP24 Is a Cancer-Associated Ubiquitin Hydrolase, Novel Tumor Suppressor, and Chromosome Instability Gene Deleted in Neuroblastoma

41. Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma

42. Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

43. Emerging Role of Ubiquitination in the Regulation of PD-1/PD-L1 in Cancer Immunotherapy

44. The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer

45. The WD40-Repeat Protein WDR-20 and the Deubiquitinating Enzyme USP-46 Promote Cell Surface Levels of Glutamate Receptors

46. Ubiquitin-specific Peptidase 6 (USP6)-associated Fibroblastic/Myofibroblastic Tumors: Evolving Concepts

47. USP30 protects against oxygen-glucose deprivation/reperfusion induced mitochondrial fragmentation and ubiquitination and degradation of MFN2

48. The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2

49. The emerging nature of Ubiquitin-specific protease 7 (USP7): a new target in cancer therapy

50. The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy

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