1. Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021
- Author
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Bert Mulder, Christian von Wintersdorff, Leonie Derickx, Marion Koopmans, Suzan D. Pas, Theun de Groot, Ewout Fanoy, Marcel Jonges, Roel Nijhuis, Tjalling Leenstra, Ali Vahidnia, Richard Molenkamp, MUMC+: DA MMI Toegelatenen (9), RS: FHML non-thematic output, Virology, and Medical Microbiology and Infection Prevention
- Subjects
2019-20 coronavirus outbreak ,medicine.medical_specialty ,Delta variant ,Routine testing ,Epidemiology ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,RT-PCR ,Biology ,Polymerase Chain Reaction ,law.invention ,SDG 3 - Good Health and Well-being ,law ,Virology ,medicine ,Humans ,Polymerase chain reaction ,Netherlands ,Public health response ,SARS-CoV-2 ,Public health ,VOC ,Public Health, Environmental and Occupational Health ,COVID-19 ,Genomics ,Rapid identification ,Regional hospital ,Real-time polymerase chain reaction ,RNA, Viral ,Rapid Communication - Abstract
We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.
- Published
- 2021