301. Fabrication of handmade paper sensor based on silver-cobalt doped copolymer-ionic liquid composite for monitoring of vitamin D3 level in real samples.
- Author
-
Anusha, Tummala, Sai Bhavani, Kalli, Shanmukha Kumar, J.V., Bonanni, Alessandra, and Brahman, Pradeep Kumar
- Subjects
- *
CHOLECALCIFEROL , *CARBON electrodes , *CONDUCTIVE ink , *VITAMIN D deficiency , *ERGOCALCIFEROL , *DETECTORS - Abstract
• Co-Ag/PANI-PPY/IL material prepared by chemical oxidative polymerization method. • Proposed sensor translated to a handmade paper sensor for real sample application. • Analysis time on handmade paper sensor was only 5 minutes. • Handmade paper sensor employed for direct detection of vitamin D 3 in real samples. • Excellent recovery in real samples making it suitable for point of care device. This paper describes the synthesis of novel material and its application to fabricate a sensing tool for the diagnosis of vitamin D deficiency. A simple and economical route for the synthesis of novel composite material based on silver-cobalt (Co-Ag) doped polyaniline-polypyrrole (PANI-PPY) copolymer and ionic liquid (IL) has been described and used as sensing material for vitamin D 3 detection. The synthesized composite was characterized using structural, morphological and electrochemical techniques. Co-Ag/PANI-PPY/IL was first used to modify the glassy carbon electrode (GCE) and applied for vitamin D 3 detection. Later a conductive ink of the proposed material was prepared and a handmade paper sensor was fabricated. Co-Ag/PANI-PPY/IL@GCE and paper electrode showed excellent electrochemical behavior towards vitamin D 3 oxidation within the concentration range of 0.0125–22.5 µM and 0.025–0.125 µM with the acceptable detection limit of 0.0073 µM and 0.015 µM respectively. Co-Ag/PANI-PPY/IL@GCE and paper electrode were successfully applied for the detection of vitamin D 3 in serum and urine samples. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF