14,727 results on '"Mediavilla, A"'
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2. Emilio Sánchez Mediavilla, Una dacha en el Golfo, Barcelona, Anagrama, 2020, 202 pp.
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Manera, Danilo, primary
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- 2024
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3. Microlensing analysis of 14.5-year light curves in SDSS J1004+4112: Quasar accretion disk size and intracluster stellar mass fraction
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Forés-Toribio, R., Muñoz, J. A., Fian, C., Jiménez-Vicente, J., and Mediavilla, E.
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Astrophysics - Astrophysics of Galaxies - Abstract
Context. The gravitational lens system SDSS J1004+4112 was the first known example of a quasar lensed by a galaxy cluster. The interest in this system has been renewed following the publication of r-band light curves spanning 14.5 years and the determination of the time delays between the four brightest quasar images. Aims. We constrained the quasar accretion disk size and the fraction of the lens mass in stars using the signature of microlensing in the quasar image light curves. Methods. We built the six possible histograms of microlensing magnitude differences between the four quasar images and compared them with simulated model histograms, using a $\chi^2$ test to infer the model parameters. Results. We infer a quasar disk half-light radius of $R_{1/2}=(0.70\pm0.04)\, R_E=(6.4\pm0.4) \sqrt{M/0.3M_{\odot}}$ light-days at 2407\r{A} in the rest frame and stellar mass fractions at the quasar image positions of $\alpha_A>0.059$, $\alpha_B=0.056^{+0.021}_{-0.027}$, $\alpha_C=0.030^{+0.031}_{-0.021}$, and $\alpha_D=0.072^{+0.034}_{-0.016}$. Conclusions. The inferred disk size is broadly compatible with most previous estimates, and the stellar mass fractions are within the expected ranges for galaxy clusters. In the region where image C lies, the stellar mass fraction is compatible with a stellar contribution from the brightest cluster galaxy, galaxy cluster members, and intracluster light, but the values at images B, D, and especially A are slightly larger, possibly suggesting the presence of extra stellar components., Comment: 7 pages, 6 figures, 2 tables, A&A in press
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- 2024
4. The Abundance of Clustered Primordial Black Holes from Quasar Microlensing
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Heydenreich, Sven, Mediavilla, Evencio, Jiménez-Vicente, Jorge, Vives-Arias, Héctor, and Muñoz, Jose A.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
While elementary particles are the favored candidate for the elusive dark matter, primordial black holes (PBHs) have also been considered to fill that role. Gravitational microlensing is a very well-suited tool to detect and measure the abundance of compact objects in galaxies. Previous studies based on quasar microlensing exclude a significant presence of substellar to intermediate-mass BHs ($\lesssim 100\,\mathrm{M}_\odot$). However, these studies were based on a spatially uniform distribution of BHs while, according to current theories of PBHs formation, they are expected to appear in clusters. We study the impact of clustering in microlensing flux magnification finding that at large scales clusters act like giant pseudo-particles, strongly affecting the emission coming from the Broad Line Region, which can no longer be used to define the zero microlensing baseline. As an alternative, we set this baseline from the intrinsic magnification ratios of quasar images predicted by macro lens models and compare them with the observed flux ratios in emission lines, infrared (IR), and radio. The (magnitude) differences are the flux-ratio anomalies attributable to microlensing, which we estimate for 35 image pairs corresponding to 12 lens systems. A Bayesian analysis indicates that the observed anomalies are incompatible with the existence of a significant population of clustered PBHs. Furthermore, we find that more compact clusters exhibit a stronger microlensing impact. Consequently, we conclude that clustering makes the existence of a significant population of BHs in the substellar to intermediate mass range even more unlikely.
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- 2024
5. Galiano, Maria Mediavilla
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Galiano, Maria Mediavilla and Galiano, Maria Mediavilla
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- 2020
6. CCT-2018-11-10-Trobada amb Núria Mediavilla, actriu de doblatge (només àudio)
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Escola Tècnica Superior d'Enginyeria Industrial de Barcelona, Mediavilla, Núria, Ojeda Rodríguez, Jordi, Escola Tècnica Superior d'Enginyeria Industrial de Barcelona, Mediavilla, Núria, and Ojeda Rodríguez, Jordi
- Abstract
Àudio de la trobada amb Núria Mediavilla, actriu de doblatge, entrevistada per Jordi Ojeda en el marc de la 4ª edició del Figueres Galàctica., Núria Mediavilla és actriu de doblatge, directora i locutora de publicitat, narració i animació. És la veu habitual en català i castellà de moltes actrius de les que cal destacar Winona Ryder, Rachel Weisz, Cameron Díaz, Kate Winslet i Uma Thurman. A l’àmbit del fantàstic ha participat en el doblatge de pel·lícules com Malèfica, Shrek, Kill Bill, Cristal Oscuro, Dentro del laberinto o, recentment, en la sèrie de televisió Stranger Things . Va doblar a Cate Blanchett en el paper de Galadriel a la saga d’”El Señor de los Anillos”., 60 minuts en català. Dissabte, 10 de novembre de 2018 a las 18:30h al Casino Menestral Figuerenc de Figueres., Més informació a: http://comiccienciatecnologia.blogspot.com.es
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- 2018
7. First Direct Evidence for Keplerian Rotation in Quasar Inner Broad Line Regions
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Fian, C., Jiménez-Vicente, J., Mediavilla, E., Muñoz, J. A., Chelouche, D., Kaspi, S., and Forés-Toribio, R.
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Astrophysics - Astrophysics of Galaxies - Abstract
We introduce a novel method to derive rotation curves with light-day spatial resolution of the inner regions of lensed quasars. We aim to probe the kinematics of the inner part of the broad-line region (BLR) by resolving the microlensing response - a proxy for the size of the emitting region - in the wings of the broad emission lines (BELs). Specifically, we assess the strength of the microlensing effects in the wings of the high-ionization lines Si IV and C IV across various velocity bins in five gravitationally lensed quasars: SDSS J1001+5027, SDSS J1004+4112, HE 1104$-$1805, SDSS J1206+4332, and SDSS J1339+1310. Using Bayesian methods to estimate the dimensions of the corresponding emission regions and adopting a Keplerian model as our baseline, we examine the consistency of the hypothesis of disk-like rotation. Our results reveal a monotonic, smooth increase in microlensing magnification with velocity. The deduced velocity-size relationships inferred for the various quasars and emission lines closely conform to the Keplerian model of an inclined disk. This study provides the first direct evidence of Keplerian rotation in the innermost region of quasars across a range of radial distances spanning from $\sim$5 to 20 light-days.
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- 2024
8. Revealing the inner workings of the lensed quasar SDSS J1339+1310: Insights from microlensing analysis
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Fian, C., Muñoz, J. A., Jiménez-Vicente, J., Mediavilla, E., Chelouche, D., Kaspi, S., and Forés-Toribio, R.
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Astrophysics - Astrophysics of Galaxies - Abstract
We aim to unveil the structure of the continuum and broad-emission line (BEL) emitting regions in the gravitationally lensed quasar SDSS J1339+1310 by examining the distinct signatures of microlensing present in this system. Our study involves a comprehensive analysis of ten years (2009-2019) of photometric monitoring data and seven spectroscopic observations acquired between 2007 and 2017. This work focuses on the pronounced deformations in the BEL profiles between images A and B, alongside the chromatic changes in their adjacent continua and the striking microlensing variability observed in the $r$-band light curves. We employed a statistical model to quantify the distribution and impact of microlensing magnifications and utilized a Bayesian approach to estimate the dimensions of various emission regions within the quasar. The analysis of the $r$-band light curves reveals substantial microlensing variability in the rest-frame UV continuum, suggesting that image B is amplified relative to image A by a factor of up to six. This finding is corroborated by pronounced microlensing-induced distortions in all studied BEL profiles (Ly$\alpha$, Si IV, C IV, C III], and Mg II), especially a prominent magnification of image B's red wing. We estimated the average dimensions of the BLR to be notably smaller than usual: the region emitting the blue wings measures $R_{1/2} = 11.5 \pm 1.7$ light-days, while the red wings originate from a more compact area of $R_{1/2} = 2.9\pm0.6$ light-days. From the photometric monitoring data, we inferred that the region emitting the $r$-band is $R_{1/2} = 2.2\pm0.3$ light-days across. Furthermore, by assessing the gravitational redshift of the UV Fe III blend and combining it with the blend's microlensing-based size estimate, we calculated the central SMBH's mass to be $M_{BH} \sim2 \times 10^8 M_\odot$.
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- 2024
9. Single-epoch and Differential Astrometric Microlensing of Quasars
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Forés-Toribio, R., Mediavilla, E., Muñoz, J. A., Jiménez-Vicente, J., Fian, C., and del Burgo, C.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We propose and discuss a new experimental approach to measure the centroid shift induced by gravitational microlensing in the images of lensed quasars (astrometric microlensing). Our strategy is based on taking the photocenter of a region in the quasar large enough as to be insensitive to microlensing as reference to measure the centroid displacement of the continuum. In this way, single-epoch measurements of astrometric microlensing can be performed. Using numerical simulations, we show that, indeed, the centroid shift monotonically decreases as the size of the emitting region increases, and only for relatively large regions, like the broad line region (BLR), does the centroid shift become negligible. This opens interesting possibilities to study the stratification of the different emitters in the accretion disk and the BLR. We estimate the amplitude of the centroid shifts for 79 gravitationally lensed images and study more thoroughly the special cases Q2237+030 A, RXJ1131-1231 A, PG1115+080 A2 and SDSS J1004+4112 A. We propose to use spectro-astrometry to simultaneously obtain the photocenters of the continuum and of different emission line regions since, with the precision of forthcoming instruments, astrometric microlensing by $\sim 1 M_\odot$ mass microlenses may be detected in many quasar lensed images. When we consider more massive micro/millilenses, $M\gtrsim 10 M_\odot$, often proposed as the constituents of dark matter, the BLR becomes sensitive to microlensing and can no longer be used as a positional reference to measure centroid shifts. Differential microlensing between the images of a lensed quasar along several epochs should be used instead., Comment: 14 pages, 6 figures, 1 table. ApJ in press
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- 2024
10. Lensing Constraints on PBHs: Substellar to Intermediate Masses
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Mediavilla, E. and Jiménez-Vicente, J.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Gravitational microlensing is a robust tool to detect and directly measure the abundance and mass of any kind of compact objects, either in our galaxy or in the extragalatic domain. On basis to generic, broadly applicable arguments, it is concluded that the observed microlensing magnifications are too small and the microlensing events less frequent than the expectations for a significant population of compact objects (other than normal stars). The detection of chromatic effects of microlensing, neither supports the presence of BHs. Detailed statistical studies of the observed microlensing magnifications and events frequency impose strict upper limits to the fraction of total mass of BHs ($\ltsim$ 1\%) from $10^{-7}M_\odot$ to indefinitely large masses. These results hold even when the BHs are distributed according to a mass spectrum or are forming clusters., Comment: 15 pages, 5 figures, To appear as Chapter 24 in the book "Primordial Black Holes", ed. Chris Byrnes, Gabriele Franciolini, Tomohiro Harada, Paolo Pani, Misao Sasaki; Springer (2024)
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- 2024
11. GROSS, Melissa, Cindy Mediavilla, & Virginia A. Walter. Five Steps of Outcome-Based Planning & Evaluation for Youth Services
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Salazar, Christina
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Five Steps of Outcome-Based Planning & Evaluation for Youth Services (Nonfiction work) -- Gross, Melissa -- Mediavilla, Cindy -- Walter, Virginia A. ,Books -- Book reviews ,Education ,Library and information science ,Publishing industry - Abstract
GROSS, Melissa, Cindy Mediavilla, & Virginia A. Walter. Five Steps of Outcome-Based Planning & Evaluation for Youth Services. 160p. ALA Editions. Jul. 2022. pap. $49.99. ISBN 9780838937327. An easy-to-follow guide [...]
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- 2023
12. Eva Aguilar-Mediavilla, Lucía Buil-Legaz, Raúl López-Penadés, Victor A. Sanchez-Azanza y Daniel Adrover-Roig (eds.) (2019): «Atypical Language Development in Romance Languages»
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Anastasiia Ogneva
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Romanic languages ,PC1-5498 ,Philology. Linguistics ,P1-1091 ,Language. Linguistic theory. Comparative grammar ,P101-410 - Published
- 2020
13. Riccardo di Mediavilla e la conoscenza del singolare
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Nannini, Andrea, Zavattero, Irene., Muller, Paola Anna Maria, paola anna maria muller (ORCID:0000-0001-7667-3795), Nannini, Andrea, Zavattero, Irene., Muller, Paola Anna Maria, and paola anna maria muller (ORCID:0000-0001-7667-3795)
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L’uomo può conoscere il singolare (intelligere singularia)? L’interrogativo, affrontato da Riccardo in due questioni (nella q. 43 delle Questioni disputate e nel Commento ai quattro Libri delle Sentenze, II d. 24 art. 3 q. 4), trova una risposta molto sfumata e non sempre univoca, espressa attraverso un linguaggio improntato all’aristotelismo, ma che apre alla metafisica avicenniana. Una conoscenza del singolare, attaccata alle sole proprietà delle cose, è possibile nonostante le strutture formali (species proprie) siano inaccessibili per l’uomo nella situazione attuale. La conoscenza del singolare è di tipo intellettuale, come testimonia la consapevolezza di conoscere il singolare. Tuttavia l’uomo conosce l’universale prima del singolare per ordine di natura: non arriva a conoscere il singolare nisi mediante universali. L’intelletto infatti attinge il singolare attraverso la mediazione dell’immaginazione rappresentativa.
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- 2021
14. Quasar Microlensing Statistics and Flux-Ratio Anomalies in Lens Models
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Mediavilla, E., Jiménez-Vicente, J., and Motta, V.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Precise lens modeling is a critical step in time delay studies of multiply imaged quasars, which are key for measuring some important cosmological parameters (specially $H_0$). However, lens models (in particular those semi-automatically generated) often show discrepancies with the observed flux-ratios between the different quasar images. These flux-ratio anomalies are usually explained through differential effects between images (mainly microlensing) that alter the intrinsic magnification ratios predicted by the models. To check this hypothesis, we collect direct measurements of microlensing to obtain the histogram of microlensing magnifications. We compare this histogram with recently published model flux-ratio anomalies and conclude that they cannot be statistically explained by microlensing. The average value of the model anomalies ($0.74\,$magnitudes) significantly exceeds the mean impact of microlensing ($0.33\,$magnitudes). Moreover, the histogram of model anomalies presents a significant tail with high anomalies ($|\Delta m| \ge 0.7$ magnitudes) which is completely unexpected from the statistics of microlensing observations. Microlensing simulations neither predict the high mean nor the fat tail of the histogram of model anomalies. We perform several statistical tests which exclude that microlensing can explain the observed flux-ratio anomalies (although Kolmogorov-Smirnov, which is less sensitive to the tail of the distributions, is not always conclusive). Thus, microlensing cannot statistically explain the bulk of flux-ratio anomalies, and models may explore different alternatives to try to reduce them. In particular, we propose to complement photometric observations with accurate flux ratios of the broad emission lines obtained from integral field spectroscopy to check and, ideally, constrain lens models.
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- 2024
15. Temperature dependence of the Raman spectrum of orthorhombic Bi2Se3
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Mediavilla-Martinez, Irene, Kramberger, Christian, Dadgostar, Shabnam, Jimenez, Juan, Ayala, Paola, Pichler, Thomas, Manjon, Francisco J., Rodriguez-Hernandez, Placida, Muñoz, Alfonso, Serebryanaya, Nadezhda, Buga, Sergei, and Serrano, Jorge
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Condensed Matter - Materials Science - Abstract
Bismuth selenide, a benchmark topological insulator, grows in a trigonal structure at ambient conditions and exhibits a number of enticing properties related to the formation of Dirac surface states. Besides this polytype, a metastable orthorhombic modification with Pnma space group has been produced by electrodeposition and high-pressure high-temperature synthesis displaying upon Sb doping significant thermoelectric properties in the midtemperature range. However, very little experimental information is available on the fundamental properties of this polytype, such as, e.g., the electronic band gap and the lattice dynamics. We report here the temperature dependence of the Raman spectra of orthorhombic Bi2Se3 between 10 K and 300 K, which displays an anharmonic behavior of the optical phonons that can be modelled with a two-phonon decay channel. In order to analyze the data we performed ab initio calculations of the electronic bandstructure, the phonon frequencies at the center of the Brillouin zone, and the phonon dispersion relations along the main symmetry directions, examining the effect of spin-orbit coupling in both phonon and electronic energies. Lastly, we report here cathodoluminescence experiments at 83 K that set a lower limit to the electronic bandgap at 0.835 eV, pointing to an indirect nature, in agreement with our calculations. These results shed light to essential properties of orthorhombic Bi2Se3 for further understanding of the potential of this semiconductor for thermoelectrics and new applications., Comment: 10 figures
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- 2024
16. Management And Operation Of The Municipal Restaurant Located At C|Mediavilla, 30. Ground And First Floor
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Restaurants ,Company business management ,Business, international - Abstract
Tenders are invited for management and operation of the municipal restaurant located at c/ mediavilla, 30. ground and first floor. Budget base for tender: 1,500.00 euros Estimated value of the [...]
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- 2023
17. Two counterexamples to a conjecture of Colin de Verdi\`ere on multiplicity
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Bourque, Maxime Fortier, Gruda-Mediavilla, Émile, Petri, Bram, and Pineault, Mathieu
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Mathematics - Spectral Theory ,Mathematics - Geometric Topology - Abstract
We exhibit closed hyperbolic surfaces of genus $10$ and $17$ such that the multiplicity of the first nonzero eigenvalue of their Laplacian is larger than the maximum conjectured by Yves Colin de Verdi\`ere in 1986. In order to determine these multiplicities, we apply the twisted Selberg trace formula to the representations induced by the isometry groups of these surfaces on corresponding triangle groups., Comment: 20 pages, 3 figures, 3 ancillary files
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- 2023
18. Creating and Managing the Full-Service Homework Center Mediavilla Cindy
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Winterhalter, Deidre
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- 2018
19. Probing the structure of the lensed quasar SDSS J1004+4112 through microlensing analysis of spectroscopic data
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Fian, C., Muñoz, J. A., Forés-Toribio, R., Mediavilla, E., Jiménez-Vicente, J., Chelouche, D., Kaspi, S., and Richards, G. T.
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Astrophysics - Astrophysics of Galaxies - Abstract
We aim to reveal the sizes of the continuum and broad emission line (BEL) emitting regions in the gravitationally lensed quasar SDSS J1004+4112 by analyzing the unique signatures of microlensing in this system. Through a comprehensive analysis of 20 spectroscopic observations acquired between 2003 and 2018, we studied the striking deformations of various BEL profiles and determined the sizes of their respective emitting regions. Our approach involves a detailed analysis of the magnitude differences in the BEL wings and their adjacent continua, and the implementation of a statistical model to quantify the distribution and impact of microlensing magnifications. To ensure a reliable baseline for no microlensing, we used the emission line cores as a reference. We then applied a Bayesian estimate to derive the size lower limits of the Ly$\alpha$, Si IV, C IV, C III], and Mg II emitting regions, as well as the sizes of the underlying continuum-emitting sources. We analyzed the outstanding microlensing-induced distortions in the line profiles of various BELs in the quasar image A, characterized by a prominent magnification of the blue part and a strong demagnification of the red part. From the statistics of microlensing magnifications and using Bayesian methods, we estimate the lower limit to the overall size of the regions emitting the BELs to be a few lt-days across, which is significantly smaller than in typically lensed quasars. The asymmetric deformations in the BELs indicate that the broad-line region is generally not spherically symmetric, and is likely confined to a plane and following the motions of the accretion disk. Additionally, the inferred continuum-emitting region sizes are larger than predictions based on standard thin-disk theory by a factor of $\sim$3.6 on average. The size-wavelength relation is consistent with that of a geometrically thin and optically thick accretion disk.
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- 2023
20. Teachers’ attitudes towards the use of virtual simulations: Design and validation of a questionnaire
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Alicia Palacios, Rosa Gómez, Álvaro Barreras, and Daniel Moreno Mediavilla
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virtual simulations ,teacher attitude ,questionnaire ,secondary teaching ,Education (General) ,L7-991 - Abstract
Virtual simulations in science classes are not used as often as might be expected if we consider the demonstrated improvement in students’ conceptual learning, the development of their skills, and their acquisition of positive emotions. This makes it necessary to identify teachers’ attitudes and perceptions to the use of these tools. The aim of this work is to construct and validate an instrument for measuring the attitudes of secondary education teachers towards the use of virtual simulations in STEM fields. Based on an in-depth theoretical review, we developed an initial questionnaire that was subjected to a process of expert validation and a pilot study. A questionnaire comprising 27 items was obtained, which was applied to 783 secondary school teachers in Spain. After carrying out confirmatory factor analysis, a scale comprising five factors was obtained. The psychometric analyses displayed satisfactory fit indices that prove the discriminant and convergent validity of the model. The result is a useful instrument for determining the principal factors that discourage teachers from habitually using simulations. This enables the design of training proposals that take teachers’ prior attitudes into account.
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- 2024
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21. Real-time PCR for malaria diagnosis and identification of Plasmodium species in febrile patients in Cubal, Angola
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Alejandro Mediavilla, Aroa Silgado, Begoña Febrer-Sendra, Beatriz Crego-Vicente, Patricia Martínez-Vallejo, Carles Rubio Maturana, Lidia Goterris, Arlette Nindia, Joan Martínez-Campreciós, Sandra Aixut, María Luisa Aznar-Ruiz-de-Alegría, Pedro Fernández-Soto, Antonio Muro, Fernando Salvador, Israel Molina, Pedro Berzosa, Inés Oliveira-Souto, and Elena Sulleiro
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Malaria ,Angola ,Plasmodium ,Diagnosis ,Real-time PCR ,Species identification ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Malaria is the parasitic disease with the highest morbimortality worldwide. The World Health Organization (WHO) estimates that there were approximately 249 million cases in 2022, of which 3.4% were in Angola. Diagnosis is based on parasite identification by microscopy examination, antigen detection, and/or molecular tests, such as polymerase chain reaction (PCR). This study aimed to evaluate the usefulness of real-time PCR as a diagnostic method for malaria in an endemic area (Cubal, Angola). Methods A cross-sectional study was carried out at the Hospital Nossa Senhora da Paz in Cubal, Angola, including 200 patients who consulted for febrile syndrome between May and July 2022. From each patient, a capillary blood sample was obtained by finger prick for malaria field diagnosis [microscopy and rapid diagnostic test (RDT)] and venous blood sample for real-time PCR performed at the Hospital Universitario Vall d’Hebron in Barcelona, Spain. Any participant with a positive result from at least one of these three methods was diagnosed with malaria. Results Of the 200 participants included, 54% were female and the median age was 7 years. Malaria was diagnosed by at least one of the three techniques (microscopy, RDT, and/or real-time PCR) in 58% of the participants, with RDT having the highest percentage of positivity (49%), followed by real-time PCR (39.5%) and microscopy (33.5%). Of the 61 discordant samples, 4 were only positive by microscopy, 13 by real-time PCR, and 26 by RDT. Plasmodium falciparum was the most frequent species detected (90.63%), followed by P. malariae (17.19%) and P. ovale (9.38%). Coinfections were detected in ten participants (15.63%): six (60%) were caused by P. falciparum and P. malariae, three (30%) by P. falciparum and P. ovale, and one (10%) triple infection with these three species. In addition, it was observed that P. falciparum and P. malariae coinfection significantly increased the parasite density of the latter. Conclusions RDT was the technique with the highest positivity rate, followed by real-time PCR and microscopy. The results of the real-time PCR may have been underestimated due to suboptimal storage conditions during the transportation of the DNA eluates. However, real-time PCR techniques have an important role in the surveillance of circulating Plasmodium species, given the epidemiological importance of the increase in non-falciparum species in the country, and can provide an estimate of the intensity of infection. Graphical abstract
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- 2024
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22. Association of depressive symptoms with incidence and mortality rates of COVID-19 over 2 years among healthcare workers in 20 countries: multi-country serial cross-sectional study
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Hiroki Asaoka, Kazuhiro Watanabe, Yuki Miyamoto, Alexandra Restrepo-Henao, Els van der Ven, Maria Francesca Moro, Lubna A. Alnasser, Olatunde Ayinde, Arin A. Balalian, Armando Basagoitia, Sol Durand-Arias, Mehmet Eskin, Eduardo Fernández-Jiménez, Freytes Frey Marcela Ines, Luis Giménez, Hans W. Hoek, Rodrigo Ezequiel Jaldo, Jutta Lindert, Humberto Maldonado, Gonzalo Martínez-Alés, Roberto Mediavilla, Clare McCormack, Javier Narvaez, Uta Ouali, Aida Barrera-Perez, Erwin Calgua-Guerra, Jorge Ramírez, Ana María Rodríguez, Dominika Seblova, Andrea Tenorio Correia da Silva, Linda Valeri, Oye Gureje, Dinarte Ballester, Mauro Giovanni Carta, Anna Isahakyan, Amira Jamoussi, Jana Seblova, Maria Teresa Solis-Soto, Ruben Alvarado, Ezra Susser, Franco Mascayano, Daisuke Nishi, and HEROES group
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COVID-19 ,Incidence rate ,Mortality rate ,Depressive symptoms ,Healthcare worker ,Multi-country study ,Medicine - Abstract
Abstract Background Long-term deterioration in the mental health of healthcare workers (HCWs) has been reported during and after the COVID-19 pandemic. Determining the impact of COVID-19 incidence and mortality rates on the mental health of HCWs is essential to prepare for potential new pandemics. This study aimed to investigate the association of COVID-19 incidence and mortality rates with depressive symptoms over 2 years among HCWs in 20 countries during and after the COVID-19 pandemic. Methods This was a multi-country serial cross-sectional study using data from the first and second survey waves of the COVID-19 HEalth caRe wOrkErS (HEROES) global study. The HEROES study prospectively collected data from HCWs at various health facilities. The target population included HCWs with both clinical and non-clinical roles. In most countries, healthcare centers were recruited based on convenience sampling. As an independent variable, daily COVID-19 incidence and mortality rates were calculated using confirmed cases and deaths reported by Johns Hopkins University. These rates represent the average for the 7 days preceding the participants’ response date. The primary outcome was depressive symptoms, assessed by the Patient Health Questionnaire-9. A multilevel linear mixed model (LMM) was conducted to investigate the association of depressive symptoms with the average incidence and mortality rates. Results A total of 32,223 responses from the participants who responded to all measures used in this study on either the first or second survey, and on both the first and second surveys in 20 countries were included in the analysis. The mean age was 40.1 (SD = 11.1), and 23,619 responses (73.3%) were from females. The 9323 responses (28.9%) were nurses and 9119 (28.3%) were physicians. LMM showed that the incidence rate was significantly and positively associated with depressive symptoms (coefficient = 0.008, standard error 0.003, p = 0.003). The mortality rate was significantly and positively associated with depressive symptoms (coefficient = 0.049, se = 0.020, p = 0.017). Conclusions This is the first study to show an association between COVID-19 incidence and mortality rates with depressive symptoms among HCWs during the first 2 years of the outbreak in multiple countries. This study’s findings indicate that additional mental health support for HCWs was needed when the COVID-19 incidence and mortality rates increase during and after the early phase of the pandemic, and these findings may apply to future pandemics. Trial registration Clinicaltrials.gov, NCT04352634.
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- 2024
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23. Quantitative assessment of urban sustainability perceptions in Lurin, Peru
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Ruth Ojeda-Zaga, Vinicio Moya-Almeida, Natalia Alvarado-Arias, and Diana Zuleta-Mediavilla
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social perception ,linear regression model ,survey ,Ecology ,QH540-549.5 - Abstract
In the current context, urban centres in Latin America are facing fundamental challenges in their endeavour for Sustainable Development. The focus of this study is the meticulous assessment of the perception of urban sustainability within the Lurín District of Peru. It introduces a system based on urban sustainability indicators, derived from social surveys and implements this system through linear regression models to discern their interrelations. The objective of the research is to quantify and evaluate essential elements linked to the management of natural resources, air and water quality, the advancement of sustainable mobility, education and the well-being of urban residents. By delineating these mathematical and statistical correlations amongst variables pertinent to urban sustainability, this study provides a robust framework for quantitative decision-making in the urban sphere. A methodology for the development of univariable and multivariable models has been demonstrated. Amongst the most important findings, it has been discovered that the variable Environmental Education System (SEA) is perceived as the least important and even negligible within the multivariable models. However, we believe this effect occurs because the impacts of education are perceived in the long term. This article contributes significantly to the academic discourse by providing a more nuanced understanding of the social perception of urban sustainability and its influence on policy formulation and decision-making processes in Latin America.
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- 2024
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24. Alain Boureau, L’inconnu dans la maison. Richard de Mediavilla, les Franciscains et la Vierge Marie à la fin du XIIIe siècle
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Lejbowicz, Max
- Abstract
On sait que, pendant les siècles centraux du Moyen Âge latin, le culte de la Vierge Marie s’est épanoui et qu’en parallèle, la théologie mariale s’est développée. Cette dernière connaît même un tournant décisif avec l’argumentation de Duns Scot en faveur de l’Immaculée Conception, qui devait tardivement devenir une vérité dogmatique (Pie IX, Ineffabilis Deus, 1854). Pour Alain Boureau, Richard de Mediavilla, « le plus thomiste des franciscains » (p. 65), a joué un rôle d’opposant dans l’élabo...
- Published
- 2022
25. An analysis of Google Translate and DeepL translation of source text typographical errors in the economic and legal fields
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Santiago Rodríguez-Rubio Mediavilla
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neural machine translation ,specialised texts ,typographical errors ,google translate ,deepl ,translation ,Language and Literature ,Romanic languages ,PC1-5498 - Abstract
Training neural machine translation systems with noisy data has been shown to improve robustness (Heigold et al., 2018). The objective of the present study is to test Google Translate and DeepL performance in the detection and correction of typographical errors, by introducing 1,820 source text typos found in a previous work on specialised Spanish-English dictionaries (Rodríguez-Rubio & Fernández-Quesada, 2020a, 2020b; Rodríguez-Rubio Mediavilla, 2021). Typos were introduced in isolation and also in co-text. Results showed that Google Translate clearly outperformed DeepL. Moreover, the repetition of the source typo was found to be the most frequent phenomenon in the machine translation output of both systems. By shedding light on the capacity of systems to deal with source text typographical errors, our study aims to provide a starting point for their refinement.
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- 2024
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26. Study Of Pumping Alternatives And Diversion Of Flows From The Queiles River And Barranco Mediavilla As It Passes Through The Town Of Tudela In Situations Of Avenue
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Business, international - Abstract
Tenders are invited for study of pumping alternatives and diversion of flows from the queiles river and barranco mediavilla as it passes through the town of tudela in situations of [...]
- Published
- 2023
27. Constraints on the Abundance of PBHs from X-ray Quasar Microlensing Observations: Substellar to Planetary Mass Range
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Esteban-Gutiérrez, A., Mediavilla, E., Jiménez-Vicente, J., and Muñoz, J. A.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We use X-ray observations of quasar microlensing (sensitive to smaller compact objects than in the optical) to study the possible presence of a population of low mass black holes (from $\sim$ $10^{-3}M_{\odot}$ to $10^{-1}M_{\odot}$) in lens galaxies. We compare these observations with microlensing magnification simulations of a mixed population of stars and black holes (BHs) plus a smooth matter component. We estimate the individual mass fractions of both, stars and BHs, for three different BH masses in the range of substellar to planetary masses. Our Bayesian analysis indicates that the contribution of BHs is negligible in the substellar mass range but that a population of BHs of planetary mass (M $\lesssim$ $10^{-3}M_{\odot}$) could pass unnoticed to X-ray microlensing. We provide new upper limits to the contribution of BHs to the fraction of dark matter based on both, the quasar microlensing data in the X-ray band, and our previous estimates in the optical of intermediate-mass BHs with an additional upper limit at $M=3M_{\odot}$., Comment: 11 pages, 3 figures
- Published
- 2023
28. Revealing the structure of the lensed quasar Q 0957+561 III. Constraints on the size of the broad-line region
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Fian, C., Muñoz, J. A., Mediavilla, E., Jiménez-Vicente, J., Motta, V., Chelouche, D., Wurzer, A., Hanslmeier, A., and Rojas, K.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
Our aim is to examine the size, kinematics, and geometry of the broad-line region (BLR) in the double-lensed quasar Q 0957+561 by analyzing the impact of microlensing on various rest-frame ultraviolet broad-emission lines (BELs). We explore the influence of intrinsic variability and microlensing on the C IV, C III], and Mg II emission lines through multiple spectroscopic observations taken between April 1999 and January 2017. By utilizing the line cores as a reference for no microlensing and correcting for the long time delay between the images, we estimate the sizes of the regions emitting the broad-line wings using a Bayesian approach. Our study of the microlensing amplitudes between the lensed images of the quasar Q 0957+561 reveals differing sizes of the regions emitting the three prominent BELs C IV, C III], and Mg II. The strength of the differential microlensing indicates that the high-ionization line C IV arises from a compact inner region of the BLR with a half-light radius of $R_{1/2} \gtrsim 16.0$ lt-days, which represents a lower limit on the overall size of the BLR and is comparable to the size of the region emitting the r-band continuum in this system. A somewhat larger size of $R_{1/2}\gtrsim 44$ lt-days is obtained for the semi-forbidden line C III]. Microlensing has a weak impact on the lower-ionization line Mg II, which is emitted from a region with a half-light radius of $R_{1/2} \gtrsim 50$ lt-days. These findings suggest that the BEL regions may have distinct geometries and kinematics, with the more extended ones being spherically symmetric, and the most compact ones being nonspherical, with motions likely confined to a plane.
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- 2023
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29. Black Hole masses for 14 gravitational lensed quasars
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Melo, A., Motta, V., Mejía-Restrepo, J., Assef, R. J., Godoy, N., Mediavilla, E., Falco, E., Kochanek, C. S., Ávila-Vera, F., and Jerez, R.
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Astrophysics - Astrophysics of Galaxies - Abstract
We estimate black hole masses (M$_{\rm BH}$) for 14 gravitationally lensed quasars using the Balmer lines along with estimates based on MgII and CIV emission lines for four and two of them, respectively. We compare with results obtained for other lensed quasars. We use spectroscopic data from the Large Binocular Telescope (LBT), Magellan and the Very Large Telescope (VLT) to measure the FWHM of the broad emission lines. Combined with the bolometric luminosity measured from the spectra energy distribution, we estimate M$_{\rm BH}$ including uncertainties from microlensing and variability. We obtain MBH using the single-epoch method from the H$\alpha$ and/or H$\beta$ broad emission lines for 14 lensed quasars, including the first estimates for QJ0158-4325, HE0512-3329 and WFI2026-4536. The masses are typical of non-lensed quasars of similar luminosity, and the implied Eddington ratios are typical. We have increased the sample of lenses with estimates of MBH by 60%., Comment: 16 pages. Submitted to A&A
- Published
- 2023
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30. Long-term optical spectral monitoring of a changing-look active galactic nucleus NGC 3516 -- II. Broad-line profile variability
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Popović, Luka C., Ilić, Dragana, Burenkov, Alexander, Álvarez, Victor Manuel Patiño, Marceta-Mandić, Sladjana, Dojcinović, Jelena Kovacević, Shablovinskaya, Elena, Kovacević, Andjelka B., Marziani, Paola, Chavushyan, Vahram, Wang, Jian-Min, Li, Yan-Rong, and Mediavilla, Evencio G.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We analyze the broad H$\beta$ line profile variability of the "changing look" active galactic nucleus (CL-AGN) NGC 3516 over a long period of 25 years. The observed change in the broad line profile may indicate a change in the geometry of the broad line region (BLR). Using spectral line profiles, we aim to explore changes in the kinematics and dimensions of the BLR in NGC 3516. We consider two possible scenarios, i.e. changes in the broad-line emission are caused by a decrease of ionization continuum emission or by the BLR obscuration by outer dusty regions. With this investigation we aim to clarify the CL mechanism of this AGN. We analyze the spectral band around the H$\beta$ line as well as the broad H$\beta$ line parameters, and how they change in time. We model the broad-line profiles assuming that there is an emission from the accretion disc superposed with an emission from a surrounding region that is outside the disc. We find that in the Type 1 activity phase, the BLR is very complex. There is a clear disc-like BLR that contributes to the broad line wings and an additional intermediate line region (ILR) that contributes to the line core. In the high activity phase, the ILR emission is close to the center of the line (in some cases slightly shifted to the red), whereas in the low activity phase (i.e., Type 2 phase), the ILR component has a significant shift to the blue, indicating an outflow. We propose that the changing look mechanism in NGC 3516 is rather connected with the intrinsic effects than with an outer obscuring region. It may still be possible that the dust has an important role in the low activity phase when it is coming inside of the BLR, making a dusty BLR. In this way, it causes a decrease in the ionization and recombination rates., Comment: 16 pages, accepted in A&A
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- 2023
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31. Real-time PCR for malaria diagnosis and identification of Plasmodium species in febrile patients in Cubal, Angola
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Mediavilla, Alejandro, Silgado, Aroa, Febrer-Sendra, Begoña, Crego-Vicente, Beatriz, Martínez-Vallejo, Patricia, Maturana, Carles Rubio, Goterris, Lidia, Nindia, Arlette, Martínez-Campreciós, Joan, Aixut, Sandra, Aznar-Ruiz-de-Alegría, María Luisa, Fernández-Soto, Pedro, Muro, Antonio, Salvador, Fernando, Molina, Israel, Berzosa, Pedro, Oliveira-Souto, Inés, and Sulleiro, Elena
- Published
- 2024
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32. Longitudinal monitoring of the mouse brain reveals heterogenous network trajectories during aging
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Özalay, Özgün, Mediavilla, Tomas, Giacobbo, Bruno Lima, Pedersen, Robin, Marcellino, Daniel, Orädd, Greger, Rieckmann, Anna, and Sultan, Fahad
- Published
- 2024
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33. Correction: Effectiveness of a scalable, remotely delivered stepped-care intervention to reduce symptoms of psychological distress among Polish migrant workers in the Netherlands: study protocol for the RESPOND randomised controlled trial
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Roos, Rinske, Witteveen, Anke B, Ayuso-Mateos, José Luis, Barbui, Corrado, Bryant, Richard A., Felez-Nobrega, Mireia, Figueiredo, Natasha, Kalisch, Rafael, Haro, Josep Maria, McDaid, David, Mediavilla, Roberto, Melchior, Maria, Nicaise, Pablo, Park, A-La, Petri-Romão, Papoula, Purgato, Marianna, van Straten, Annemieke, Tedeschi, Federico, Underhill, James, and Sijbrandij, Marit
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- 2024
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34. Clases dentro de las clases: Innovación docente para el alumnado del Máster en Formación del Profesorado de matemáticas
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Rosa Gómez Del Amo, Pedro Peinado Rocamora, and Daniel Moreno-Mediavilla
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formación de docentes de secundaria ,tecnología educacional ,aprendizaje en línea ,innovación pedagógica. ,aprendizaje activo ,enseñanza de las matemáticas ,Education - Abstract
La formación del profesorado y la innovación en el ámbito académico son procesos básicos para la mejora de la calidad de la educación. En este trabajo se presenta una experiencia didáctica innovadora para el alumnado del Máster Universitario en Formación del Profesorado en Educación Secundaria y Bachillerato, de una universidad online, en la especialidad de matemáticas. La innovación educativa surge tras la detección de dificultades en la asimilación de los contenidos impartidos en la asignatura de Innovación Docente e Iniciación a la Investigación Educativa por parte del alumnado participante. La experiencia consiste en una interacción simultánea real (online) entre el alumnado del Máster de la especialidad de matemáticas y el alumnado de Bachillerato de un centro público de Educación Secundaria, de España, mientras estos reciben clases en su centro de manera presencial. La metodología didáctica utilizada en esta experiencia se basa en los principios del Aula Invertida y, en todo momento, se ha compartido con el alumnado del Máster el material necesario para su comprensión y asimilación. Para analizar esta experiencia se ha utilizado un cuestionario de recogida de información antes y después de la experiencia, una encuesta de satisfacción y un focus group. Los resultados indican que el alumnado del Máster online considera muy necesaria esta experiencia, ya que favorece la percepción del entorno al que deben adaptarse y, además, la visualización de casos reales aporta una visión significativa que completa y complementa la formación teórica recibida.
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- 2024
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35. Methodological design in the use of virtual simulations in Chemistry: A systematic review
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Alicia Palacios Ortega, Virginia Pascual López, and Daniel Moreno Mediavilla
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educational technology, chemistry teaching, teaching method, secondary school teaching ,Education ,Special aspects of education ,LC8-6691 ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Virtual simulations are a very useful educational resource to improve the teaching of chemistry. Their use makes it possible to facilitate the comprehension of concepts, promotes the development of scientific competences and even improves student attitudes toward chemistry. However, it is important to point out that a simulation by itself is not enough to improve student learning. Methodological design is a crucial aspect in order for its classroom use to be significant. Simulations must form part of an instructional sequence that promotes said learning, and thus the role of the instructor is key. This work conducts a systematic review with the aim of analyzing how to apply the use of simulations in the teaching of chemistry in secondary schools, delving deeper into the way in which simulations are used from a methodological perspective, in order to improve the learning processes and results. In this sense, it was found that there is an improvement in learning on both the level of content comprehension and in scientific competences. Guided research is also identified as the most effective methodology for the application of simulations in the classroom. With a look to the future, it is suggested that there is a need to conduct research on the continued use of simulations in the classroom, as well as their characteristics and the instructional methods used.
- Published
- 2024
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36. Five Steps of Outcome-Based Planning and Evaluation for Public Libraries Gross Melissa Mediavilla Cindy Walter Virginia A.
- Author
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Powell, Lisa
- Published
- 2016
37. Fast Multipole Method for Gravitational Lensing. Application to High Magnification Quasar Microlensing
- Author
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Vicente, J. Jiménez and Mediavilla, E.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We introduce the use of the Fast Multipole Method (FMM) to speed up gravitational lensing ray tracing calculations. The method allows very fast calculation of ray deflections when a large number of deflectors, $N_*$, is involved, while keeping rigorous control on the errors. In particular, we apply this method, in combination with the Inverse Polygon Mapping technique (IPM), to quasar microlensing to generate microlensing magnification maps with very high workloads (high magnification, large size and/or high resolution) that require a very large number of deflectors. Using, FMM-IPM, the computation time can be reduced by a factor $\sim 10^5$ with respect to standard Inverse Ray Shooting, making the use of this algorithm on a personal computer comparable to the use of standard IRS on GPUs. We also provide a flexible web interface for easy calculation of microlensing magnification maps using FMM-IPM\footnote{http://gloton.ugr.es/microlensing/}. We exemplify the power of this new method by applying it to some challenging interesting astrophysical scenarios, including clustered primordial black holes, or extremely magnified stars close to the giant arcs of galaxy clusters. We also show the performance/use of FMM to calculate ray deflection for a halo resulting from cosmological simulations composed by a large number ($N\gtrsim 10^7$) of elements., Comment: 17 pages, 10 figures. Accepted for publication in The Astrophysical Journal. Accompanying web for microlensing map calculation at https://gloton.ugr.es/microlensing/
- Published
- 2022
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38. Beyond effectiveness in eHealth trials: Process evaluation of a stepped-care programme to support healthcare workers with psychological distress (RESPOND-HCWs)
- Author
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Roberto Mediavilla, Blanca García-Vázquez, Kerry R. McGreevy, James Underhill, Carmen Bayón, María-Fe Bravo-Ortiz, Ainoa Muñoz-Sanjosé, Josep Maria Haro, Anna Monistrol-Mula, Pablo Nicaise, Papoula Petri-Romão, David McDaid, A-La Park, Maria Melchior, Cécile Vuillermoz, Giulia Turrini, Beatrice Compri, Marianna Purgato, Rinske Roos, Anke B. Witteveen, Marit Sijbrandij, Richard A. Bryant, Daniela Fuhr, and José Luis Ayuso-Mateos
- Subjects
Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Objectives This study presents the process evaluation of an effective stepped-care programme of eHealth interventions (Doing What Matters in Times of Stress [DWM] and Problem Management Plus [PM+]) for healthcare workers (HCWs) with psychological distress (RESPOND-HCWs trial) conducted in Spain. The aim is to analyse the context in which the programme was delivered, assess key implementation outcomes and explore mechanisms of action. Methods We used mixed methods. Quantitative data came from routine randomised control trial monitoring and structured observation, and qualitative data were collected using semi-structured, in-depth interviews with trial participants ( n = 12) and decision-makers ( n = 7) and a focus group discussion with intervention providers ( n = 7). We conducted a descriptive analysis of quantitative data using R software and a thematic analysis of qualitative data using NVivo. Results Context analysis revealed implementation barriers, including unrealistic expectations of participants about the programme and mental health-related stigma. The flexibility of interventions and the opportunity for mental health actions were enabling factors. Implementation outcomes showed that the trial was feasible, appropriate and timely, and that the intervention was delivered with minimal protocol deviations and good acceptance among participants. Mechanisms of action included confidence in the positive effect of the intervention, a good therapeutic relationship and specific intervention components. Conclusions These results supplement the outcome evaluation and can help inform large-scale implementation in similar settings. Specific recommendations include increasing mental health awareness and reducing stigma in the implementation setting, including a short orientation session and ensuring flexibility in schedules and peer support. Trial registration number NCT04980326.
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- 2024
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39. Is language impaired in Spanish-speaking children with autism spectrum disorder level 1?
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Alberto Sánchez Pedroche, Mario Valera-Pozo, Angelica Mateus Moreno, Maria Fernanda Lara Díaz, Eva Aguilar-Mediavilla, and Daniel Adrover-Roig
- Subjects
Special aspects of education ,LC8-6691 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
The current diagnostic criteria for the autism spectrum disorder (ASD) include the possibility to specify concomitant language difficulties. Purpose Our main aim was to explore whether children with ASD-Level 1 (ASD-L1) present difficulties in the acquisition of structural language, as little work has been done in this regard so far. As a secondary aim we evaluated the degree to which the potential language impairment in ASD is directly associated with their social communication deficits or it represents a distinct deficit. Methods To further clarify the nature and characteristics of putative language difficulties in ASD-L1, we evaluated language skills in 89 children and preadolescents diagnosed with ASD-L1, and a group of typically developing participants (TD). All of them were between 8 and 13 years old and had similar socioeconomic backgrounds. Results Children with ASD-L1 obtained lower scores than those in TD group in repeating sentences, in finding the semantic relationships between words, and in applying word structure rules (morphology). Congruently, the core language standard score was lower in the ASD-L1 group, and the proportion of language delay was significantly higher in the ASD-L1 group than in the control group. Conclusion Language scores were associated with autistic traits; thus, language performance in ASD-L1 is closely related to autistic symptoms. These results are discussed according to the literature on linguistic deficits in ASD-L1 and their relations with phonological working memory.
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- 2024
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40. Usefulness of real-time PCR for urogenital schistosomiasis diagnosis in preschool children in a high-prevalence area in Angola.
- Author
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Alejandro Mediavilla, Aroa Silgado, Raquel Sánchez-Marqués, Cristina Bocanegra, Arlette Nindia, Fernando Salvador, Zeferino Pintar, Patricia Martínez-Vallejo, Carles Rubio Maturana, Lidia Goterris, Joan Martínez-Campreciós, Sandra Aixut, Inés Oliveira-Souto, María Luisa Aznar-Ruiz-de-Alegría, María Espiau, Israel Molina, and Elena Sulleiro
- Subjects
Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
BackgroundUrogenital schistosomiasis caused by Schistosoma haematobium is highly endemic in the municipality of Cubal in Angola. Currently, diagnosis is based on the observation of S. haematobium eggs in urine samples by microscopy but this method has low sensitivity. Few studies have been performed using molecular techniques in high-prevalence areas for the detection of S. haematobium. The objective of this study is to evaluate the usefulness of real-time PCR as a diagnostic technique for urogenital schistosomiasis among preschool-age children and its correlation with morbidity data.MethodsA cross-sectional study was conducted in Cubal, Angola, involving 97 urine samples from preschool-age children analyzed by the dipstick test, microscopic examination of filtered urine, and real-time PCR. The diagnosis of urogenital schistosomiasis was based on microscopy and/or real-time PCR results. Clinical and ultrasonography evaluation was performed to rule out complications of schistosomiasis.ResultsWe detected a total of 64.95% of samples positive by real-time PCR and 37.11% by microscopy. The sensitivity of parasitological diagnosis of urogenital schistosomiasis by real-time PCR and microscopy was 95.45% and 54.55%, respectively, and the sensitivity of real-time PCR compared with microscopy was 91.67%. A positive real-time PCR result was significantly related to older age (mean = 3.22 years), detection of eggs by microscopy, and abnormal urine dipstick results (18.56% with proteinuria, 31.96% with leukocyturia, and 31.96% with microhematuria) (p-valueConclusionsReal-time PCR is a more sensitive technique than microscopy for urinary schistosomiasis diagnosis in preschool-age children in Cubal. This increase in sensitivity would allow earlier diagnosis and treatment, thus reducing the morbidity associated with schistosomiasis in its early stages.
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- 2024
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41. Power of Light: Raman Spectroscopy and Machine Learning for the Detection of Lung Cancer
- Author
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Harun Hano, Charles H. Lawrie, Beatriz Suarez, Alfredo Paredes Lario, Ibone Elejoste Echeverría, Jenifer Gómez Mediavilla, Marina Izaskun Crespo Cruz, Eneko Lopez, and Andreas Seifert
- Subjects
Chemistry ,QD1-999 - Published
- 2024
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42. Longitudinal monitoring of the mouse brain reveals heterogenous network trajectories during aging
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Özgün Özalay, Tomas Mediavilla, Bruno Lima Giacobbo, Robin Pedersen, Daniel Marcellino, Greger Orädd, Anna Rieckmann, and Fahad Sultan
- Subjects
Biology (General) ,QH301-705.5 - Abstract
Abstract The human aging brain is characterized by changes in network efficiency that are currently best captured through longitudinal resting-state functional MRI (rs-fMRI). These studies however are challenging due to the long human lifespan. Here we show that the mouse animal model with a much shorter lifespan allows us to follow the functional network organization over most of the animal’s adult lifetime. We used a longitudinal study of the functional connectivity of different brain regions with rs-fMRI under anesthesia. Our analysis uncovers network modules similar to those reported in younger mice and in humans (i.e., prefrontal/default mode network (DMN), somatomotor and somatosensory networks). Statistical analysis reveals different patterns of network reorganization during aging. Female mice showed a pattern akin to human aging, with de-differentiation of the connectome, mainly due to increases in connectivity of the prefrontal/DMN cortical networks to other modules. Our male cohorts revealed heterogenous aging patterns with only one group confirming the de- differentiation, while the majority showed an increase in connectivity of the somatomotor cortex to the Nucleus accumbens. In summary, in line with human work, our analysis in mice supports the concept of de-differentiation in the aging mammalian brain and reveals additional trajectories in aging mice networks.
- Published
- 2024
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43. Independencia, diseño y cooperación de bancos centrales en economías interdependientes / Juan Carlos Negrete Mediavilla ; director Francisco Alcalá Agulló
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Negrete Mediavilla, Juan Carlos
- Subjects
336.711 ,Bancos centrales - Abstract
Tesis-Universidad de Murcia., Consulte la tesis en: BCA. GENERAL. ARCHIVO UNIVERSITARIO. TM 1297.
- Published
- 2018
44. Tras la huella de Azorín : el teatro español en el último tercio del siglo XIX / Antonio Díez Mediavilla ; director Mariano de Paco
- Author
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Díez Mediavilla, Antonio
- Abstract
Tesis-Universidad de Murcia., Consulte la tesis en: BCA. GENERAL. ARCHIVO UNIVERSITARIO. T.M.-441.
- Published
- 2018
45. A Mass Model for the Lensing Cluster SDSS J1004+4112: Constraints From the Third Time Delay
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Forés-Toribio, R., Muñoz, J. A., Kochanek, C. S., and Mediavilla, E.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We have built a new model for the lens system SDSS J1004+4112 including the recently measured time delay of the fourth quasar image. This time delay has a strong influence on the inner mass distribution of the lensing cluster ($\rho \propto r^{-\alpha}$) allowing us to determine $\alpha=1.18^{+0.02(+0.11)}_{-0.03(-0.18)}$ at the 68% (95%) confidence level in agreement with hydrodynamical simulations of massive galaxy clusters. We find an offset between the brightest cluster galaxy (BCG) and the dark matter halo of $3.8^{+0.6(+1.4)}_{-0.7(-1.3)}$ kpc at 68% (95%) confidence which is compatible with other galaxy cluster measurements. As an observational challenge, the estimated time delay between the leading image C and the faint (I=24.7) fifth image E is roughly 8 yr., Comment: 9 pages, 3 figures, 4 tables. ApJ in press
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- 2022
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46. Concentration of low-density lipoproteins (LDL) is significantly reduced after nilotinib discontinuation
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Roa-Chamorro, Ricardo, Puerta-Puerta, José Manuel, Torres-Quintero, Lucía, Jaén-Águila, Fernando, González-Bustos, Pablo, Rodríguez-Gil, Miguel Ángel, and Mediavilla-García, Juan Diego
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- 2023
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47. Abundance of LIGO/Virgo Black Holes from Microlensing Observations of Quasars with Reverberation Mapping Size Estimates
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Esteban-Gutiérrez, A., Mediavilla, E., Jiménez-Vicente, J., Agües-Paszkowsky, N., Muñoz, J. A., and Heydenreich, S.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Assuming a population of Black Holes (BHs) with masses in the range inferred by LIGO/Virgo from BH mergers, we use quasar microlensing observations to estimate their abundances. We consider a mixed population of stars and BHs and the presence of a smooth dark matter component. We adopt reverberation mapping estimates of the quasar size. According to a Bayesian analysis of the measured microlensing magnifications, a population of BHs with masses $\sim$ 30$M_{\odot}$ constitutes less than 0.4 % of the total matter at 68 % confidence level (less than 0.9 % at 90 % confidence). We have explored the whole mass range of LIGO/Virgo BHs finding that this upper limit ranges from 0.5 % to 0.4 % at 68 % C.L. (from 1.1 % to 0.9 % at 90 % C.L.) when the BHs mass change from 10 to 60$M_{\odot}$. We estimate a 16 % contribution from the stars, in agreement with previous studies based on a single mass population that do not consider explicitly the presence of BHs. These results are consistent with the estimates of BH abundances from the statistics of LIGO/Virgo mergers and rule out that PBHs (or any type of compact objects), in this mass range constitute a significant fraction of the dark matter., Comment: 14 pages, 5 figures, 1 table
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- 2022
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48. Limiting the Abundance of LIGO/Virgo Black Holes with Microlensing Observations of Quasars of Finite Size
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Esteban-Gutiérrez, A., Mediavilla, E., Jiménez-Vicente, J., Agües-Paszkowsky, N., Muñoz, J. A., and Heydenreich, S.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a simple but general argument that strongly limits the abundance of Primordial Black Holes (PBHs) (or other unknown population of compact objects) with masses similar to those determined by LIGO/Virgo from BH binary mergers. We show that quasar microlensing can be very sensitive to the mass of the lenses, and that it is able to distinguish between stars and BHs of high mass, when the finite size of the source is taken into account. A significant presence of massive BHs would produce frequent high flux magnifications (except for unrealistically large sources) which have been very rarely observed. On the contrary, a typical stellar population would induce flux magnifications consistent with the observations. This result excludes PBHs (or any type of compact object) in the mass range determined by LIGO/Virgo as the main dark matter constituents in the lens galaxies., Comment: 5 pages, 1 figure
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- 2022
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49. Carrie Scott Banks and Cindy Mediavilla. Libraries & Gardens: Growing Together. Chicago, IL: ALA Editions, 2019. 144p. Paper. $57.99 (ISBN 978-0-8389-1855-5). LC 2018059577
- Author
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Gregory Laynor
- Subjects
media_common.quotation_subject ,Library science ,Conversation ,Sociology ,Library and Information Sciences ,Space (commercial competition) ,Information center ,Experiential learning ,media_common - Abstract
In Libraries & Gardens: Growing Together , Carrie Scott Banks and Cindy Mediavilla bring librarianship into conversation with gardening. While the histories of gardens and libraries are intertwined, there has not been much written about library gardens. Banks and Mediavilla’s book encourages us to look at how library gardens “extend and enhance the library’s role as an information center and community space” (x). Writing from public library backgrounds, Banks and Mediavilla focus on how library gardens can contribute to the inclusiveness and accessibility of libraries. The book gives a tour of various kinds of library gardens, including many academic and research library gardens. In discussing library gardens, Libraries & Gardens: Growing Together contributes to a broader conversation about libraries as multisensory, experiential places.
- Published
- 2019
50. Efecto de la resiliencia en la inteligencia emocional y la satisfacción vital en técnicos de deportes de montaña
- Author
-
Laura Martín-Talavera, Lázaro Mediavilla-Saldaña, David Molero, and Óscar Gavín-Chocano
- Subjects
bienestar ,deportes de montaña ,inteligencia emocional percibida ,resiliencia ,satisfacción vital ,Special aspects of education ,LC8-6691 ,Sports ,GV557-1198.995 - Abstract
Los deportes de montaña tienen unas características propias, diferentes a otras modalidades deportivas en la naturaleza con características similares. La inteligencia emocional y la resiliencia son susceptibles de afectar positivamente al desempeño deportivo en condiciones extremas. En este estudio, participaron 788 deportistas mayores de 18 años (mayoría de edad en España) de la Federación Española de Deportes de Montaña y Escalada (FEDME), 593 hombres (75.3 %), 193 mujeres (24.5 %) y 2 personas (0.3 %) que consideraban ser de la categoría “otro género” (no binario, etc.). La edad media era de 49.8 años (± 12.8). Se utilizó como instrumentos la Escala de Resiliencia (RS-14), Wong Law Emotional Intelligence Scale (WLEIS-S) y Satisfaction With Life Scale (SWLS). El objetivo era aportar evidencias sobre el potencial de la resiliencia entre la inteligencia emocional y satisfacción vital en deportistas de montaña y escalada. Los resultados del modelo de ecuaciones estructurales (SEM) mostraron elevados coeficientes de determinación en las variables resiliencia [(Q2 =.553); (R²=.663)] y satisfacción vital [(Q2 =.301); (R²=.422)]. La presente investigación precisará en el futuro de la realización de estudios específicos por modalidad deportiva para este ámbito, con un elevado número de practicantes y disciplinas, así como sus posibles aplicaciones para la mejora de factores emocionales.
- Published
- 2024
- Full Text
- View/download PDF
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