175 results on '"Carroli, Guillermo"'
Search Results
2. Multicountry research on comprehensive abortion policy implementation in Latin America: a mixed-methods study protocol
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Gialdini, Celina, primary, Ramón Michel, Agustina, additional, Romero, Mariana, additional, Ramos, Silvina, additional, Carroli, Guillermo, additional, Carroli, Berenise, additional, Gomez Ponce de León, Rodolfo, additional, Vila Ortiz, Mercedes, additional, and Lavelanet, Antonella, additional
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- 2024
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3. Implementing the QUALI-DEC project in Argentina, Burkina Faso, Thailand and Viet Nam: a process delineation and theory-driven process evaluation protocol
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Cleeve, Amanda, primary, Annerstedt, Kristi Sidney, additional, Betrán, Ana Pilar, additional, Mölsted Alvesson, Helle, additional, Kaboré Wendyam, Charles, additional, Carroli, Guillermo, additional, Lumbiganon, Pisake, additional, Nhu Hung, Mac Quoc, additional, Zamboni, Karen, additional, Opiyo, Newton, additional, Bohren, Meghan A., additional, El Halabi, Soha, additional, Gialdini, Celina, additional, Vila Ortiz, Mercedes, additional, Escuriet, Ramón, additional, Robson, Michael, additional, Dumont, Alexandre, additional, and Hanson, Claudia, additional
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- 2023
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4. Factors affecting the implementation of calcium supplementation strategies during pregnancy to prevent pre-eclampsia: a mixed-methods systematic review
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Cormick, Gabriela, primary, Moraa, Hellen, additional, Zahroh, Rana Islamiah, additional, Allotey, John, additional, Rocha, Thaís, additional, Peña-Rosas, Juan Pablo, additional, Qureshi, Zahida P, additional, Hofmeyr, G Justus, additional, Mistry, Hema, additional, Smits, Luc, additional, Vogel, Joshua Peter, additional, Palacios, Alfredo, additional, Gwako, George N, additional, Abalos, Edgardo, additional, Larbi, Koiwah Koi, additional, Carroli, Guillermo, additional, Riley, Richard, additional, Snell, Kym IE, additional, Thorson, Anna, additional, Young, Taryn, additional, Betran, Ana Pilar, additional, Thangaratinam, Shakila, additional, and Bohren, Meghan A, additional
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- 2023
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5. Calcium supplementation to prevent pre-eclampsia: protocol for an individual participant data meta-analysis, network meta-analysis and health economic evaluation
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Rocha, Thaís, primary, Allotey, John, additional, Palacios, Alfredo, additional, Vogel, Joshua Peter, additional, Smits, Luc, additional, Carroli, Guillermo, additional, Mistry, Hema, additional, Young, Taryn, additional, Qureshi, Zahida P, additional, Cormick, Gabriela, additional, Snell, Kym I E, additional, Abalos, Edgardo, additional, Pena-Rosas, Juan-Pablo, additional, Khan, Khalid Saeed, additional, Larbi, Koiwah Koi, additional, Thorson, Anna, additional, Singata-Madliki, Mandisa, additional, Hofmeyr, George Justus, additional, Bohren, Meghan, additional, Riley, Richard, additional, Betran, Ana Pilar, additional, and Thangaratinam, Shakila, additional
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- 2023
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6. Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight
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Kiserud, Torvid, Piaggio, Gilda, Carroli, Guillermo, Widmer, Mariana, Carvalho, José, Jensen, Lisa Neerup, Giordano, Daniel, Cecatti, José Guilherme, Aleem, Hany Abdel, Talegawkar, Sameera A., Benachi, Alexandra, Diemert, Anke, Kitoto, Antoinette Tshefu, Thinkhamrop, Jadsada, Lumbiganon, Pisake, Tabor, Ann, Kriplani, Alka, Perez, Rogelio Gonzalez, Hecher, Kurt, Hanson, Mark A., Gülmezoglu, A. Metin, and Platt, Lawrence D.
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Biological sciences - Abstract
Author(s): Torvid Kiserud, Gilda Piaggio, Guillermo Carroli, Mariana Widmer, José Carvalho, Lisa Neerup Jensen, Daniel Giordano, José Guilherme Cecatti, Hany Abdel Aleem, Sameera A. Talegawkar, Alexandra Benachi, Anke Diemert, Antoinette [...]
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- 2021
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7. Maternal and Neonatal Individual Risks and Benefits Associated with Caesarean Delivery: Multicentre Prospective Study
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Villar, José, Carroli, Guillermo, Zavaleta, Nelly, Donner, Allan, Wojdyla, Daniel, Faundes, Anibal, Velazco, Alejandro, Bataglia, Vicente, Langer, Ana, Narváez, Alberto, Valladares, Eliette, Shah, Archana, Campodónico, Liana, Romero, Mariana, Reynoso, Sofia, de Pádua, Karla Simônia, Giordano, Daniel, Kublickas, Marius, and Acosta, Arnaldo
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- 2007
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8. Duration of third stage labour and postpartum blood loss: a secondary analysis of the WHO CHAMPION trial data
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Chikkamath, Sumangala B., primary, Katageri, Geetanjali M., additional, Mallapur, Ashalata A., additional, Vernekar, Sunil S., additional, Somannavar, Manjunath S., additional, Piaggio, Gilda, additional, Carroli, Guillermo, additional, de Carvalho, José Ferreira, additional, Althabe, Fernando, additional, Hofmeyr, G. Justus, additional, Widmer, Mariana, additional, Gulmezoglu, Ahmet Metin, additional, and Goudar, Shivaprasad S., additional
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- 2021
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9. Abortion-related morbidity in six Latin American and Caribbean countries: findings of the WHO/HRP multi-country survey on abortion (MCS-A)
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Romero, Mariana, primary, Gomez Ponce de Leon, Rodolfo, additional, Baccaro, Luiz Francisco, additional, Carroli, Berenise, additional, Mehrtash, Hedieh, additional, Randolino, Jimena, additional, Menjivar, Elisa, additional, Estevez Saint-Hilaire, Erika, additional, Huatuco, Maria del Pilar, additional, Hernandez Muñoz, Rosalinda, additional, Garcia Camacho, Gabriela, additional, Thwin, Soe Soe, additional, Campodonico, Liana, additional, Abalos, Edgardo, additional, Giordano, Daniel, additional, Gamerro, Hugo, additional, Kim, Caron Rahn, additional, Ganatra, Bela, additional, Gülmezoglu, Metin, additional, Tuncalp, Özge, additional, and Carroli, Guillermo, additional
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- 2021
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10. Costs of publicly provided maternity services in Rosario, Argentina
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Borghi Josephine, Bastus Silvia, Belizan María, Carroli Guillermo, Hutton Guy, and Fox-Rushby Julia
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cost ,maternal health ,pregnancy ,delivery ,Argentina ,Public aspects of medicine ,RA1-1270 - Abstract
OBJECTIVE: This study estimates the costs of maternal health services in Rosario, Argentina. MATERIAL AND METHODS: The provider costs (US$ 1999) of antenatal care, a normal vaginal delivery and a caesarean section, were evaluated retrospectively in two municipal hospitals. The cost of an antenatal visit was evaluated in two health centres and the patient costs associated with the visit were evaluated in a hospital and a health centre. RESULTS: The average cost per hospital day is $114.62. The average cost of a caesarean section ($525.57) is five times greater than that of a normal vaginal delivery ($105.61). A normal delivery costs less at the general hospital and a c-section less at the maternity hospital. The average cost of an antenatal visit is $31.10. The provider cost is lower at the health centre than at the hospital. Personnel accounted for 72-94% of the total cost and drugs and medical supplies between 4-26%. On average, an antenatal visit costs women $4.70. Direct costs are minimal compared to indirect costs of travel and waiting time. CONCLUSIONS: These results suggest the potential for increasing the efficiency of resource use by promoting antenatal care visits at the primary level. Women could also benefit from reduced travel and waiting time. Similar benefits could accrue to the provider by encouraging normal delivery at general hospitals, and complicated deliveries at specialised maternity hospitals.
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- 2003
11. Routine Episiotomy Should Be Abandoned
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Belizán, José M. and Carroli, Guillermo
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- 1998
12. WHO Is Producing a Reproductive Health Library for Developing Countries
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Gülmezoglu, A. Metin, Villar, José, Carroli, Guillermo, Hofmeyr, Justus, Langer, Ana, Schulz, Ken, and Guidotti, Richard
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- 1997
13. Selection of mothers with increased risk of delivery low birthweight newborns at a public maternity hospital in Rosario, Argentina
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Belizan, Jose, Nardin, Juan Carlos, Carroli, Guillermo, and Campodonico, Liana
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RISK ,ARGENTINA ,purl.org/becyt/ford/3.3 [https] ,Low Birthweight ,purl.org/becyt/ford/3 [https] - Abstract
A retrospective analysis was made of births occurring over a six-month period at apublic maternity hospital in the city of Rosario, Argentina, with a view to planningactions reducing the likelihood of low birthweight deliveries. Fifteen risk factorswere assessed. While a history of delivering a low birthweight infant was theleading risk factor for both intrauterine growth retardation and preterm delivery,the other leading risk factors for these two types of low birthweight newbornsdiffered. Many variables relating to socioeconomic and cultural levels that havetraditionally been considered risk factors for low birthweight did not display anysignificant association.Risk calculations for the study population were made using data gathered at thepatients? first prenatal checkup. These calculations indicated that mothers with oneor more of four leading risk factors (a history of deliver&g low birthweight newborns, smoking more than two cigarettes a day, weighing less than 46 kg, and beingless than 148 cm tall) constituted only 26.6% of the study populati.on but accountedfor 51.6% of the low birthweight deliveries. Such screening can provide an effectiveway of selecting high-risk mothers, and simple analyses of this sort are essential inplanning health actions relating to low birthweight deliveries. Fil: Belizan, Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Centro Rosarino de Estudios Perinatales; Argentina Fil: Nardin, Juan Carlos. Centro Rosarino de Estudios Perinatales; Argentina Fil: Carroli, Guillermo. Centro Rosarino de Estudios Perinatales; Argentina Fil: Campodonico, Liana. Centro Rosarino de Estudios Perinatales; Argentina
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- 2020
14. Elective induction versus spontaneous labour in Latin America/Declenchement du travail sans indication medicale contre travail spontane en Amerique latine/Induccion electiva frente a parto espontaneo en Latinoamerica
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Guerra, Glaucia Virginia, Cecatti, Jose Guilherme, Souza, Joao Paulo, Faundes, Anibal, Morais, Sirlei Siani, Gulmezoglu, Ahmet Metin, Passini, Jr., Renato, Parpinellia, Mary Angela, and Carroli, Guillermo
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Childbirth -- Physiological aspects ,Treatment outcome -- Health aspects -- Research ,Forced labor -- Health aspects ,Health - Abstract
Objective To assess the frequency of elective induction of labour and its determinants in selected Latin America countries; quantify success in attaining vaginal delivery, and compare rates of caesarean and adverse maternal and perinatal outcomes after elective induction versus spontaneous labour in low-risk pregnancies. Methods Of 37 444 deliveries in women with low-risk pregnancies, 1847 (4.9%) were electively induced. The factors associated with adverse maternal and perinatal outcomes among cases of spontaneous and induced onset of labour were compared. Odds ratios for factors potentially associated with adverse outcomes were calculated, as were the relative risks of having an adverse maternal or perinatal outcome (both with their 95% confidence intervals). Adjustment using multiple logistic regression models followed these analyses. Findings Of 11 077 cases of induced labour, 1847 (16.7%) were elective. Elective inductions occurred in 4.9% of women with low-risk pregnancies (37 444). Oxytocin was the most common method used (83% of cases), either alone or combined with another. Of induced deliveries, 88.2% were vaginal. The most common maternal adverse events were: (i) a higher postpartum need for uterotonic drugs, (ii) a nearly threefold risk of admission to the intensive care unit; (iii) a fivefold risk of postpartum hysterectomy, and (iv) an increased need for anaesthesia/analgesia. Perinatal outcomes were satisfactory except for a 22% higher risk of delayed breastfeeding (i.e. initiation between 1 hour and 7 days postpartum). Conclusion Caution is mandatory when indicating elective labour induction because the increased risk of maternal and perinatal adverse outcomes is not outweighed by clear benefits. Objectif Evaluer la frequence du declenchement du travail sans indication medicale et ses determinants dans une selection de pays d'Amerique latine, quantifier la reussite d'un accouchement par voie vaginale et comparer les taux de cesariennes et d'issues perinatales et maternelles negatives apres le declenchement du travail sans indication medicale par rapport au travail spontane, dans des grossesses a faible risque. Methodes Sur 37 444 accouchements de femmes presentant des grossesses a faible risque, 1 847 (4,9%) ont ete declenches sans indication medicale. On a compare les facteurs associes aux issues perinatales et maternelles negatives dans des cas de debut de travail spontane et declenche. On a calcule les rapports des cotes des facteurs potentiellement associes aux issues negatives, ainsi que les risques relatifs d'issue perinatale ou maternelle negative (tous deux avec un intervalle de confiance de 95%). Suite a ces analyses, un ajustement a ete effectue a l'aide de plusieurs modeles de regression logistique. Resultats Sur 11 077 cas de travail declenche, 1 847 (16,7%) l'ont ete sans indication medicale. Un declenchement du travail sans indication medicale a ete effectue chez 4,9% des femmes des grossesses a faible risque (37 444). L'ocytocine etait la methode la plus communement utilisee (83% des cas), soit administree seule, soit combinee avec une autre methode. Pour les accouchements sans indication medicale, 88,2% ont eu lieu par voie vaginale. Les evenements maternels negatifs les plus communs etaient: (i) un besoin superieur de medicaments uterotoniques postpartum, (il) un risque presque multiplie par 3 d'admission en unite de soins intensifs; (iii) un risque multiplie par 5 d'hysterectomie postpartum et (iv) une augmentation du besoin d'anesthesie/analgesie. Les issues perinatales etaient satisfaisantes, a l'exception d'une augmentation de 22% du risque d'allaitement retarde (c'est-a-dire une initiation entre 1 heure et 7 jours apres l'accouchement). Conclusion II est indispensable de faire preuve de prudence lors de la preconisation d'un accouchement sans indication medicale, car l'augmentation du risque d'issues perinatales et maternelles negatives n'est pas compensee par des avantages clairs. Objetivo Evaluar la frecuencia de los partos inducidos electivos y sus factores determinantes en determinados paises de Latinoamerica; cuantificar el exito en la consecucion de partos vaginales y comparar los porcentajes de cesareas y de resultados maternos y perinatales adversos tras un parto inducido electivo con respecto a un parto espontaneo en embarazos de bajo riesgo. Metodos De 37 444 partos de mujeres con embarazos de bajo riesgo, 1847 (4,9%) fueron partos inducidos etectivos. Se compararon los factores asociados a resultados matemos y perinatales adversos en los casos de inicio del parto espontaneo e inducido. Se calcularon los cocientes de posibilidades para los factores posiblemente asociados a resultados adversos, asi como los riesgos relacionados con un resultado materno o perinatal adverso (ambos con un intervalo de confianza del 95%). Despues de llevar a cabo estos analisis, se realizo un ajuste empleando modelos de regresion logistica multiple. Resultados De los 11 077 casos de parto inducido, 1847 (16,7%) fueron electivos. Las inducciones electivas se produjeron en un 4,9% de mujeres con embarazos de bajo riesgo (37 444). El metodo mas utilizado fue la oxitocina (83% de los casos), como farmaco unico o en combinacion con otros medicamentos. Un 88,2% de los partos inducidos fueron vaginales. Los acontecimientos matemos adversos mas comunes fueron: (i) una mayor necesidad de medicamentos uterotonicos tras el parto, (ii) un riesgo casi tres veces mayor de ingreso en la unidad de cuidados intensivos; (iii) un riesgo cinco veces mayor de histerectomia posparto y (iv) una mayor necesidad de anestesicos/analgesicos. Los resultados perinataies fueron satisfactorios excepto por un riesgo un 22% mayor de lactancia materna retardada (es decir, el inicio de la misma entre 1 hora y 7 dias despues del parto). Conclusion La precaucion es obligatoria a la hora de recomendar una induccion electiva del parto, ya que el aumento del riesgo de resultados adversos matemos y perinatales no se ve compensado por unos beneficios claros., Introduction Elective labour induction without any medical or obstetric indication has been increasing in recent years. In some countries, 10% of all deliveries are electively induced. (1-4) This increase has [...]
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- 2011
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15. Methodological considerations in implementing the WHO Global Survey for Monitoring Maternal and Perinatal Health/Considerations methodologiques dans l'application de l'Enquete mondiale de l'OMS sur la surveillance de la sante maternelle et perinatale/Consideraciones metodologicas a raiz de la Encuesta mundial OMS de vigilancia de la salud materna y perinatal
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Shah, Archana, Faundes, Anibal, Machoki, M'Imunya, Bataglia, Vicente, Amokrane, Faouzi, Donner, Allan, Mugerwa, Kidza, Carroli, Guillermo, Fawole, Bukola, Langer, Ana, Wolomby, Jean Jose, Naravaez, Alberto, Nafiou, Idi, Kublickas, Marius, Valladares, Eliette, Velasco, Alejandro, Zavaleta, Nelly, Neves, Isilda, and Villar, Jose
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World Health Organization -- Surveys ,Maternal health services -- Surveys ,Health surveys -- Methods - Abstract
Objective To set up a global system for monitoring maternal and perinatal health in 54 countries worldwide. Methods The WHO Global Survey for Monitoring Maternal and Perinatal Health was implemented through a network of health institutions, selected using a stratified multistage cluster sampling design. Focused information on maternal and perinatal health was abstracted from hospital records and entered in a specially developed online data management system. Data were collected over a two- to three-month period in each institution. The project was coordinated by WHO and supported by WHO regional offices and country coordinators in Africa and the Americas. Findings The initial survey was implemented between September 2004 and March 2005 in the African and American regions. A total of 125 institutions in seven African countries and 119 institutions in eight Latin American countries participated. Conclusion This project has created a technologically simple and scientifically sound system for large-scale data management, which can facilitate programme monitoring in countries. Objectif Mettre en place dans 54 pays repartis dans l'ensemble du monde un systeme mondial de surveillance de la sante maternelle et perinatale. Methodes L'Enquete mondiale sur la surveillance de la sante maternelle et perinatale de I'OMS s'est operee par le biais d'un reseau d'etablissements de soins, selectionnes par echantillonnage en grappe stratifie a plusieurs niveaux. Une information ciblee sur la sante maternelle et perinatale a ete extraite des registres hospitaliers et entree dans un systeme de gestion des donnees en ligne, specialement developpe. Les donnees ont ete recueillies sur une periode de deux a trois mois dans chaque etablissement. Le projet a ete coordonne par I'OMS et appuye par les bureaux regionaux de I'OMS et par ses coordinateurs nationaux en Afrique et dans les Ameriques. Resultats L'enquete initiale a ete realisee entre septembre 2004 et mars 2005 en Afrique et dans les Ameriques. Ont participe au total a l'enquete 125 etablissements de sept pays africains et 119 etablissements de huit pays d'Amerique latine. Conclusion Ce projet a cree un systeme technologiquement simple et scientifiquement rigoureux pour la gestion grande echelle des donnees, pouvant faciliter la surveillance programmatique dans les pays. Objetivo Establecer un sistema mundial de vigilancia de la salud materna y perinatal en 54 paises de todo el mundo. Metodos La Encuesta mundial OMS de vigilancia de la salud materna y perinatal se llevo a cabo a traves de una red de instituciones sanitarias seleccionadas mediante muestreo polietapico estratificado por conglomerados. La informacion focalizada y resumida sobre la salud materna y perinatal extraida a partir de las historias clinicas se introdujo en un sistema de gestion de datos en linea especialmente desarrollado. A lo largo de un periodo de dos a tres meses se reunieron datos en cada institucion. El proyecto fue coordinado por la OMS y respaldado por las oficinas regionales de la OMS y los coordinadores en los paises en Africa y las Americas. Resultados La encuesta inicial se llevo a cabo entre septiembre de 2004 y marzo de 2005 en las regiones de Africa y de las Americas. Participaron en total 125 instituciones de siete paises africanos y 119 instituciones de ocho paises latinoamericanos. Conclusion Este proyecto ha generado un sistema tecnologicamente sencillo y cientificamente solido para gestionar datos a gran escala, lo cual puede facilitar la vigilancia de los programas en los paises. [TEXT NOT REPRODUCIBLE IN ASCII], Introduction The WHO Global Survey on Maternal and Perinatal Health aims to develop a network of health institutions worldwide that collects up-to-date information on services provided and on how evidence-based [...]
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- 2008
16. Implementation and evaluation of nonclinical interventions for appropriate use of cesarean section in low- and middle-income countries: protocol for a multisite hybrid effectiveness-implementation type III trial
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Dumont, Alexandre, Betrán, Ana Pilar, Kaboré, Charles, de Loenzien, Myriam, Lumbiganon, Pisake, Bohren, Meghan A., Mac, Quoc Nhu Hung, Opiyo, Newton, Carroli, Guillermo, Annerstedt, Kristi Sidney, Ridde, Valéry, Escuriet, Ramón, Robson, Michael, and Hanson, Claudia
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Low- and middle-income countries ,Cesarean Section ,Quality of care ,Infant, Newborn ,Parturition ,Nonclinical intervention ,Study Protocol ,Unnecessary cesarean section ,Cross-Sectional Studies ,Pregnancy ,Humans ,Female ,Healthcare organization ,Developing Countries ,Poverty ,Shared decision-making - Abstract
Background While cesarean sections (CSs) are a life-saving intervention, an increasing number are performed without medical reasons in low- and middle-income countries (LMICs). Unnecessary CS diverts scarce resources and thereby reduces access to healthcare for women in need. Argentina, Burkina Faso, Thailand, and Vietnam are committed to reducing unnecessary CS, but many individual and organizational factors in healthcare facilities obstruct this aim. Nonclinical interventions can overcome these barriers by helping providers improve their practices and supporting women’s decision-making regarding childbirth. Existing evidence has shown only a modest effect of single interventions on reducing CS rates, arguably because of the failure to design multifaceted interventions effectively tailored to the context. The aim of this study is to design, adapt, and test a multifaceted intervention for the appropriate use of CS in Argentina, Burkina Faso, Thailand, and Vietnam. Methods We designed an intervention (QUALIty DECision-making—QUALI-DEC) with four components: (1) opinion leaders at heathcare facilities to improve adherence to best practices among clinicians, (2) CS audits and feedback to help providers identify potentially avoidable CS, (3) a decision analysis tool to help women make an informed decision on the mode of birth, and (4) companionship to support women during labor. QUALI-DEC will be implemented and evaluated in 32 hospitals (8 sites per country) using a pragmatic hybrid effectiveness-implementation design to test our implementation strategy, and information regarding its impact on relevant maternal and perinatal outcomes will be gathered. The implementation strategy will involve the participation of women, healthcare professionals, and organizations and account for the local environment, needs, resources, and social factors in each country. Discussion There is urgent need for interventions and implementation strategies to optimize the use of CS while improving health outcomes and satisfaction in LMICs. This can only be achieved by engaging all stakeholders involved in the decision-making process surrounding birth and addressing their needs and concerns. The study will generate robust evidence about the effectiveness and the impact of this multifaceted intervention. It will also assess the acceptability and scalability of the intervention and the capacity for empowerment among women and providers alike. Trial registration ISRCTN67214403
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- 2020
17. Additional file 2 of Implementation and evaluation of nonclinical interventions for appropriate use of cesarean section in low- and middle-income countries: protocol for a multisite hybrid effectiveness-implementation type III trial
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Dumont, Alexandre, Betrán, Ana Pilar, Kaboré, Charles, Loenzien, Myriam De, Pisake Lumbiganon, Bohren, Meghan A., Mac, Quoc Nhu Hung, Opiyo, Newton, Carroli, Guillermo, Annerstedt, Kristi Sidney, Ridde, Valéry, Escuriet, Ramón, Robson, Michael, and Hanson, Claudia
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Additional file 2. Extended cost-effectiveness analysis od QUALI-DEC.
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- 2020
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18. Additional file 3 of Implementation and evaluation of nonclinical interventions for appropriate use of cesarean section in low- and middle-income countries: protocol for a multisite hybrid effectiveness-implementation type III trial
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Dumont, Alexandre, Betrán, Ana Pilar, Kaboré, Charles, Loenzien, Myriam De, Pisake Lumbiganon, Bohren, Meghan A., Mac, Quoc Nhu Hung, Opiyo, Newton, Carroli, Guillermo, Annerstedt, Kristi Sidney, Ridde, Valéry, Escuriet, Ramón, Robson, Michael, and Hanson, Claudia
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Data_FILES - Abstract
Additional file 3. Knowledge transfer strategy.
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- 2020
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19. The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight
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Kiserud, Torvid, Piaggio, Gilda, Carroli, Guillermo, Widmer, Mariana, Carvalho, José, Neerup Jensen, Lisa, Giordano, Daniel, Cecatti, José Guilherme, Abdel Aleem, Hany, Talegawkar, Sameera A., Benachi, Alexandra, Diemert, Anke, Tshefu Kitoto, Antoinette, Thinkhamrop, Jadsada, Lumbiganon, Pisake, Tabor, Ann, Kriplani, Alka, Gonzalez Perez, Rogelio, Hecher, Kurt, Hanson, Mark A., Gülmezoglu, A. Metin, and Platt, Lawrence D.
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Diagnostic ultrasonography -- Usage ,Biometry -- Usage ,Fetal development -- Statistics ,Biometric technology ,Biological sciences - Abstract
Background Perinatal mortality and morbidity continue to be major global health challenges strongly associated with prematurity and reduced fetal growth, an issue of further interest given the mounting evidence that fetal growth in general is linked to degrees of risk of common noncommunicable diseases in adulthood. Against this background, WHO made it a high priority to provide the present fetal growth charts for estimated fetal weight (EFW) and common ultrasound biometric measurements intended for worldwide use. Methods and Findings We conducted a multinational prospective observational longitudinal study of fetal growth in low-risk singleton pregnancies of women of high or middle socioeconomic status and without known environmental constraints on fetal growth. Centers in ten countries (Argentina, Brazil, Democratic Republic of the Congo, Denmark, Egypt, France, Germany, India, Norway, and Thailand) recruited participants who had reliable information on last menstrual period and gestational age confirmed by crown-rump length measured at 8-13 wk of gestation. Participants had anthropometric and nutritional assessments and seven scheduled ultrasound examinations during pregnancy. Fifty-two participants withdrew consent, and 1,387 participated in the study. At study entry, median maternal age was 28 y (interquartile range [IQR] 25-31), median height was 162 cm (IQR 157-168), median weight was 61 kg (IQR 55-68), 58% of the women were nulliparous, and median daily caloric intake was 1,840 cal (IQR 1,487-2,222). The median pregnancy duration was 39 wk (IQR 38-40) although there were significant differences between countries, the largest difference being 12 d (95% CI 8-16). The median birthweight was 3,300 g (IQR 2,980-3,615). There were differences in birthweight between countries, e.g., India had significantly smaller neonates than the other countries, even after adjusting for gestational age. Thirty-one women had a miscarriage, and three fetuses had intrauterine death. The 8,203 sets of ultrasound measurements were scrutinized for outliers and leverage points, and those measurements taken at 14 to 40 wk were selected for analysis. A total of 7,924 sets of ultrasound measurements were analyzed by quantile regression to establish longitudinal reference intervals for fetal head circumference, biparietal diameter, humerus length, abdominal circumference, femur length and its ratio with head circumference and with biparietal diameter, and EFW. There was asymmetric distribution of growth of EFW: a slightly wider distribution among the lower percentiles during early weeks shifted to a notably expanded distribution of the higher percentiles in late pregnancy. Male fetuses were larger than female fetuses as measured by EFW, but the disparity was smaller in the lower quantiles of the distribution (3.5%) and larger in the upper quantiles (4.5%). Maternal age and maternal height were associated with a positive effect on EFW, particularly in the lower tail of the distribution, of the order of 2% to 3% for each additional 10 y of age of the mother and 1% to 2% for each additional 10 cm of height. Maternal weight was associated with a small positive effect on EFW, especially in the higher tail of the distribution, of the order of 1.0% to 1.5% for each additional 10 kg of bodyweight of the mother. Parous women had heavier fetuses than nulliparous women, with the disparity being greater in the lower quantiles of the distribution, of the order of 1% to 1.5%, and diminishing in the upper quantiles. There were also significant differences in growth of EFW between countries. In spite of the multinational nature of the study, sample size is a limiting factor for generalization of the charts. Conclusions This study provides WHO fetal growth charts for EFW and common ultrasound biometric measurements, and shows variation between different parts of the world., Author(s): Torvid Kiserud 1,2,*, Gilda Piaggio 3,4,*, Guillermo Carroli 5, Mariana Widmer 6,*, José Carvalho 4, Lisa Neerup Jensen 7, Daniel Giordano 5, José Guilherme Cecatti 8, Hany Abdel Aleem [...]
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- 2017
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20. Causes of stillbirths and early neonatal deaths: data from 7993 pregnancies in six developing countries/Causes de mortinatalite et de mortalite neonatale precoce: donnees portant sur 7993 grossesses dans six pays en developpement/Causas de mortinatalidad y de mortalidad neonatal precoz: datos de 7993 embarazos en sels paises en desarrollo
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Ngoc, Nhu Thi Nguyen, Merialdi, Mario, Abdel-Aleem, Hany, Carroli, Guillermo, Purwar, Manorama, Zavaleta, Nelly, Campodonico, Liana, Ali, Mohamed M., Hofmeyr, G. Justus, Mathai, Matthews, Lincetto, Ornella, and Villar, Jose
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Developing countries -- Health aspects ,Developing countries -- Reports ,Still-birth -- Causes of ,Still-birth -- Statistics ,Infants -- Patient outcomes ,Infants -- Causes of ,Infants -- Statistics - Abstract
Objective To report stillbirth and early neonatal mortality and to quantify the relative importance of different primary obstetric causes of perinatal mortality in 171 perinatal deaths from 7993 pregnancies that ended after 28 weeks in nulliparous women. Methods A review of all stillbirths and early newborn deaths reported in the WHO calcium supplementation trial for the prevention of pre-eclampsia conducted at seven WHO collaborating centres in Argentina, Egypt, India, Peru, South Africa and Viet Nam. We used the Baird--Pattinson system to assign primary obstetric causes of death and classified causes of early neonatal death using the International classification of diseases and related health problems, Tenth revision (ICD-10). Findings Stillbirth rate was 12.5 per 1000 births and early neonatal mortality rate was 9.0 per 1000 live births. Spontaneous preterm delivery and hypertensive disorders were the most common obstetric events leading to perinatal deaths (28.7% and 23.6%, respectively). Prematurity was the main cause of early neonatal deaths (62%). Conclusions Advancements in the care of premature infants and prevention of spontaneous preterm labour and hypertensive disorders of pregnancy could lead to a substantial decrease in perinatal mortality in hospital settings in developing countries. Objectif Faire etat de la mortinatalite et de la mortalite neonatale precoce et quantifier l'importance relative des principales causes obstetricales de mortalite perinatale observees pour 171 deces perinatals lies a 7993 grossesses interrompues apres la 28eme semaine chez des femmes nullipares. Methodes L'examen a porte sur tous les cas de mortinatalite et deces neonatals precoces signales dans l'essai OMS de supplementation calcique pour la prevention de la preeclampsie mene dans sept centres collaborateurs situes en Afrique du Sud, en Argentine, en Egypte, en Inde, au Perou et au Vietnam. On a utilise le systeme de Baird-Pattinson pour attribuer les principales causes obstetricales de deces et classe les causes des deces neonatals precoces sur la base de la Classification internationale des maladies et des problemes de sante connexes, dixieme revision (CIM 10). Resultats Le taux de mortinatalite est de 12,5 pour 1000 naissances et le taux de mortalite neonatale precoce de 9,0 pour 1000 naissances vivantes. L'accouchement premature spontane et l'hypertension gravidique sont les problemes obstetricaux les plus frequemment a l'origine d'un deces perinatal (respectivement 28,7% et 23,6 %). La prematurite est la principale cause de deces neonatal precoce (62 %). Conclusion Des progres dans les soins aux prematures et la prevention du travail premature spontane et de l'hypertension gravidique permettraient d'obtenir une diminution sensible de la mortalite perinatale en milieu hospitalier dans les pays en developpement. Objetivo Informar sobre la mortinatalidad y la mortalidad neonatal precoz y cuantificar la importancia relativa de diferentes causas obstetricas primarias de mortalidad perinatal en 171 defunciones perinatales correspondientes a 7993 embarazos de mas de 28 semanas en mujeres nuliparas. Metodos Se examinaron todos los casos de mortinatalidad y defuncion precoz de recien nacidos notificados en un ensayo OMS de administracion de suplementos de calcio para la prevencion de la preeclampsia, llevado a cabo en siete centros colaboradores de la OMS en la Argentina, Egipto, la India, el Peru, Sudafrica y Viet Nam. Usamos el sistema de Baird-Pattinson para asignar causas obstetricas primarias de muerte y causas clasificadas de mortalidad neonatal precoz mediante la Clasificacion Estadistica Internacional de Enfermedades y Problemas de Salud Conexos, decima revision (CIE-10). Resultados La tasa de mortinatalidad fue del 12,5 por 1000 nacimientos, y la tasa de mortalidad neonatal precoz, de 9,0 por 1000 nacidos vivos. EI parto pretermino espontaneo y los trastornos hipertensivos fueron los casos obstetricos mas comunes asociados a las defunciones perinatales (28,7% y 23,6%, respectivamente). La prematuridad fue la causa principal de las defunciones neonatales precoces (62%). Conclusiones Los progresos de la atencion a los lactantes prematuros y la prevencion del parto pretermino espontaneo y de los trastornos hipertensivos del embarazo podrian propiciar una disminucion sustancial de la mortalidad perinatal en los entornos hospitalarios en los paises en desarrollo., Introduction A two-thirds reduction of mortality in children less than 5 years old by 2015 is one of the UN Millennium Development Goals. (1) Despite a decline in mortality in [...]
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- 2006
21. Nutritional interventions during pregnancy for the prevention or treatment of impaired fetal growth: an overview of randomized controlled trials
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Merialdi, Mario, Carroli, Guillermo, Villar, Jose, Abalos, Edgardo, Gulmezoglu, A. Metin, Kulier, Regina, and de Onis, Mercedes
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Nutrition counseling -- Evaluation ,Pregnant women -- Food and nutrition ,Birth weight, Low -- Prevention ,Dietary supplements -- Health aspects ,Food/cooking/nutrition - Abstract
This paper reviews the efficacy of nutrition interventions to prevent or treat impaired fetal growth. Searches were made for Cochrane systematic reviews and randomized controlled trials published before October 2002. Balanced protein energy supplementation reduced the risk of small for gestational age (SGA) by 30% (95%Cl: 20% to 43%) while one trial conducted in New York, U.S., reported a negative effect of high protein supplementation on SGA (RR 1.58; 95%Cl: 1.03-2.41). Calcium supplementation protected against low birth weight (RR 0.83; 95%Cl: 0.71-0.98). Micronutrient supplements did not affect birth weight, except for magnesium supplementation, which reduced the risk of SGA by 30%. This finding, however, needs or be interpreted with caution because of methodological issues in the data analysis. Programmatic recommendations can be made only for intervening with balanced protein energy supplements, especially in population with a high prevalence of undernutrition. Research is needed to determine the efficacy of multiple micronutrient supplementation and the effect of single micronutrients supplementation on specific growth outcomes such as fetal organ and bone growth. In addition, the public health relevance of these outcomes and their relation to morbidity need to be evaluated. KEY WORDS: * nutritional interventions * fetal growth * birth weight * small for gestational age * randomized controlled trials
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- 2003
22. Nutritional interventions during pregnancy for the prevention or treatment of maternal morbidity and preterm delivery: an overview of randomized controlled trials
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Villar, Jose, Merialdi, Mario, Gulmezoglu, A. Metin, Abalos, Edgardo, Carroli, Guillermo, Kulier, Regina, and de Oni, Mercedes
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Dietary supplements -- Health aspects ,Premature birth -- Prevention ,Pregnant women -- Food and nutrition ,Nutrition counseling -- Evaluation ,Food/cooking/nutrition - Abstract
This overview assesses the effectiveness of nutritional interventions to prevent or treat maternal morbidity, mortality and preterm delivery. Cochrane systematic reviews and other up-to-date systematic reviews and individual randomized controlled trials were sought. Searches were carried out up to July 2002. Iron and folate supplements reduce anemia and should be included in antenatal care programs. Calcium supplementation to women at high risk of hypertension during pregnancy or low calcium intake reduced the incidence of both preeclampsia and hypertension. Fish oil and vitamins E and C are promising for preventing preeclampsia and preterm delivery and need further testing. Vitamin A and [beta]-carotene reduced maternal mortality in a large trial; ongoing trials should provide further evaluation. No specific nutrient supplementation was identified for reducing preterm delivery. Nutritional advice, magnesium, fish oil and zinc supplementation appear promising and should be tested alone or together in methodologically sound randomized controlled trials. Anema in pregnancy can be prevented and treated effectively. Considering the multifactorial etiology of the other conditions evaluated, it is unlikely that any specific nutrient on its own, blanket interventions or magic bullets will prevent or treat preeclampsia, hemorrhage, obstructed labor, infections, preterm delivery or death during pregnancy. The few promising interventions for specific outcomes should be tested or reconsidered when results of ongoing trials become available. Until then, women and their families should receive support to improve their diets as a general health rule, which is a basic human right. KEY WORDS: * nutritional interventions * maternal morbidity * preterm delivery * randomized controlled trials
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- 2003
23. High fever after sublingual administration of misoprostol for treatment of post‐partum haemorrhage: a hospital‐based, prospective observational study in Argentina
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Durocher, Jill, primary, Aguirre, Jesus Daniel, additional, Dzuba, Ilana G., additional, Mirta Morales, Elba, additional, Carroli, Guillermo, additional, Esquivel, Jesica, additional, Martin, Roxanne, additional, Berecoechea, Cecilia, additional, and Winikoff, Beverly, additional
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- 2020
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24. Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
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Durocher, Jill, primary, Dzuba, Ilana G., additional, Carroli, Guillermo, additional, Morales, Elba Mirta, additional, Aguirre, Jesus Daniel, additional, Martin, Roxanne, additional, Esquivel, Jesica, additional, Carroli, Berenise, additional, and Winikoff, Beverly, additional
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- 2019
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25. Characteristics of Randomized Controlled Trials Included in Systematic Reviews of Nutritional Interventions Reporting Maternal Morbidity, Mortality, Preterm Delivery, Intrauterine Growth Restriction and Small for Gestational Age and Birth Weight Outcomes
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Villar, José, Merialdi, Mario, Gülmezoglu, A. Metin, Abalos, Edgardo, Carroli, Guillermo, Kulier, Regina, and de Onis, Mercedes
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- 2003
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26. Perinatal Factors Associated with Blood Pressure during Childhood
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Bergel, Eduardo, Haelterman, Edwige, Belizán, José, Villar, José, and Carroli, Guillermo
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- 2000
27. The world health organization multicountry survey on maternal and newborn health: study protocol
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Souza João, Gülmezoglu Ahmet, Carroli Guillermo, Lumbiganon Pisake, and Qureshi Zahida
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Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Effective interventions to reduce mortality and morbidity in maternal and newborn health already exist. Information about quality and performance of care and the use of critical interventions are useful for shaping improvements in health care and strengthening the contribution of health systems towards the Millennium Development Goals 4 and 5. The near-miss concept and the criterion-based clinical audit are proposed as useful approaches for obtaining such information in maternal and newborn health care. This paper presents the methods of the World Health Organization Multicountry Study in Maternal and Newborn Health. The main objectives of this study are to determine the prevalence of maternal near-miss cases in a worldwide network of health facilities, evaluate the quality of care using the maternal near-miss concept and the criterion-based clinical audit, and develop the near-miss concept in neonatal health. Methods/Design This is a large cross-sectional study being implemented in a worldwide network of health facilities. A total of 370 health facilities from 29 countries will take part in this study and produce nearly 275,000 observations. All women giving birth, all maternal near-miss cases regardless of the gestational age and delivery status and all maternal deaths during the study period comprise the study population. In each health facility, medical records of all eligible women will be reviewed during a data collection period that ranges from two to three months according to the annual number of deliveries. Discussion Implementing the systematic identification of near-miss cases, mapping the use of critical evidence-based interventions and analysing the corresponding indicators are just the initial steps for using the maternal near-miss concept as a tool to improve maternal and newborn health. The findings of projects using approaches similar to those described in this manuscript will be a good starter for a more comprehensive dialogue with governments, professionals and civil societies, health systems or facilities for promoting best practices, improving quality of care and achieving better health for mothers and children.
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- 2011
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28. A cluster randomized controlled trial to evaluate the effectiveness of the clinically integrated RHL evidence -based medicine course
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Mittal Suneeta, Lumbiganon Pisake, Cecatti Jose G, Germar Maria J, Carroli Guillermo, Gulmezoglu A Metin, Khan Khalid S, Kulier Regina, Pattinson Robert, Wolomby-Molondo Jean-Jose, Bergh Anne-Marie, and May Win
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Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background and objectives Evidence-based health care requires clinicians to engage with use of evidence in decision-making at the workplace. A learner-centred, problem-based course that integrates e-learning in the clinical setting has been developed for application in obstetrics and gynaecology units. The course content uses the WHO reproductive health library (RHL) as the resource for systematic reviews. This project aims to evaluate a clinically integrated teaching programme for incorporation of evidence provided through the WHO RHL. The hypothesis is that the RHL-EBM (clinically integrated e-learning) course will improve participants' knowledge, skills and attitudes, as well as institutional practice and educational environment, as compared to the use of standard postgraduate educational resources for EBM teaching that are not clinically integrated. Methods The study will be a multicentre, cluster randomized controlled trial, carried out in seven countries (Argentina, Brazil, Democratic Republic of Congo, India, Philippines, South Africa, Thailand), involving 50-60 obstetrics and gynaecology teaching units. The trial will be carried out on postgraduate trainees in the first two years of their training. In the intervention group, trainees will receive the RHL-EBM course. The course consists of five modules, each comprising self-directed e-learning components and clinically related activities, assignments and assessments, coordinated between the facilitator and the postgraduate trainee. The course will take about 12 weeks, with assessments taking place pre-course and 4 weeks post-course. In the control group, trainees will receive electronic, self-directed EBM-teaching materials. All data collection will be online. The primary outcome measures are gain in EBM knowledge, change in attitudes towards EBM and competencies in EBM measured by multiple choice questions (MCQs) and a skills-assessing questionniare administered eletronically. These questions have been developed by using questions from validated questionnaires and adapting them to the current course. Secondary outcome measure will be educational environment towards EBM which will be assessed by a specifically developed questionnaire. Expected outcomes The trial will determine whether the RHL EBM (clinically integrated e-leraning) course will increase knowledge, skills and attitudes towards EBM and improve the educational environment as compared to standard teaching that is not clinically integrated. If effective, the RHL-EBM course can be implemented in teaching institutions worldwide in both, low-and middle income countries as well as industrialized settings. The results will have a broader impact than just EBM training because if the approach is successful then the same educational strategy can be used to target other priority clinical and methodological areas. Trial Registration ACTRN12609000198224
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- 2010
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29. WHO Global Survey on Maternal and Perinatal Health in Latin America: classifying caesarean sections
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Faúndes Anibal, Velasco Alejandro, Narváez Alberto, Langer Ana, Torloni Maria R, Carroli Guillermo, Widmer Mariana, Wojdyla Daniel, Souza João P, Merialdi Mario, Robson Michael, Gulmezoglu A Metin, Betrán Ana P, Acosta Arnaldo, Valladares Eliette, Romero Mariana, Zavaleta Nelly, Reynoso Sofia, and Bataglia Vicente
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Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background Caesarean section rates continue to increase worldwide with uncertain medical consequences. Auditing and analysing caesarean section rates and other perinatal outcomes in a reliable and continuous manner is critical for understanding reasons caesarean section changes over time. Methods We analyzed data on 97,095 women delivering in 120 facilities in 8 countries, collected as part of the 2004-2005 Global Survey on Maternal and Perinatal Health in Latin America. The objective of this analysis was to test if the "10-group" or "Robson" classification could help identify which groups of women are contributing most to the high caesarean section rates in Latin America, and if it could provide information useful for health care providers in monitoring and planning effective actions to reduce these rates. Results The overall rate of caesarean section was 35.4%. Women with single cephalic pregnancy at term without previous caesarean section who entered into labour spontaneously (groups 1 and 3) represented 60% of the total obstetric population. Although women with a term singleton cephalic pregnancy with a previous caesarean section (group 5) represented only 11.4% of the obstetric population, this group was the largest contributor to the overall caesarean section rate (26.7% of all the caesarean sections). The second and third largest contributors to the overall caesarean section rate were nulliparous women with single cephalic pregnancy at term either in spontaneous labour (group 1) or induced or delivered by caesarean section before labour (group 2), which were responsible for 18.3% and 15.3% of all caesarean deliveries, respectively. Conclusion The 10-group classification could be easily applied to a multicountry dataset without problems of inconsistencies or misclassification. Specific groups of women were clearly identified as the main contributors to the overall caesarean section rate. This classification could help health care providers to plan practical and effective actions targeting specific groups of women to improve maternal and perinatal care.
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- 2009
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30. Active management of the third stage of labour without controlled cord traction: a randomized non-inferiority controlled trial
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Derman Richard, Lumbiganon Pisake, Hofmeyr G Justus, Carroli Guillermo, Abdel-Aleem Hany, Elbourne Diana, Qureshi Zahida, Piaggio Gilda, Merialdi Mario, Widmer Mariana, Gülmezoglu A Metin, Okong Pius, Goudar Shivaprasad, Festin Mario, Althabe Fernando, and Armbruster Deborah
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Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Background The third stage of labour refers to the period between birth of the baby and complete expulsion of the placenta. Some degree of blood loss occurs after the birth of the baby due to separation of the placenta. This period is a risky period because uterus may not contract well after birth and heavy blood loss can endanger the life of the mother. Active management of the third stage of labour (AMTSL) reduces the occurrence of severe postpartum haemorrhage by approximately 60–70%. Active management consists of several interventions packaged together and the relative contribution of each of the components is unknown. Controlled cord traction is one of those components that require training in manual skill for it to be performed appropriately. If it is possible to dispense with controlled cord traction without losing efficacy it would have major implications for effective management of the third stage of labour at peripheral levels of health care. Objective The primary objective is to determine whether the simplified package of oxytocin 10 IU IM/IV is not less effective than the full AMTSL package. Methods A hospital-based, multicentre, individually randomized controlled trial is proposed. The hypothesis tested will be a non-inferiority hypothesis. The aim will be to determine whether the simplified package without CCT, with the advantage of not requiring training to acquire the manual skill to perform this task, is not less effective than the full AMTSL package with regard to reducing blood loss in the third stage of labour. The simplified package will include uterotonic (oxytocin 10 IU IM) injection after delivery of the baby and cord clamping and cutting at approximately 3 minutes after birth. The full package will include the uterotonic injection (oxytocin 10 IU IM), controlled cord traction following observation of uterine contraction and cord clamping and cutting at approximately 3 minutes after birth. The primary outcome measure is blood loss of 1000 ml or more at one hour and up to two hours for women who continue to bleed after one hour. The secondary outcomes are blood transfusion, the use of additional uterotonics and measure of severe morbidity and maternal death. We aim to recruit 25,000 women delivering vaginally in health facilities in eight countries within a 12 month recruitment period. Management Overall trial management will be from HRP/RHR in Geneva. There will be eight centres located in Argentina, Egypt, India, Kenya, Philippines, South Africa, Thailand and Uganda. There will be an online data entry system managed from HRP/RHR. The trial protocol was developed following a technical consultation with international organizations and leading researchers in the field. Expected outcomes The main objective of this trial is to investigate whether a simplified package of third stage management can be recommended without increasing the risk of PPH. By avoiding the need for a manual procedure that requires training, the third stage management can be implemented in a more widespread and cost-effective way around the world even at the most peripheral levels of the health care system. This trial forms part of the programme of work to reduce maternal deaths due to postpartum haemorrhage within the RHR department in collaboration with other research groups and organizations active in the field. Trial Registration ACTRN12608000434392
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- 2009
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31. Womens' opinions on antenatal care in developing countries: results of a study in Cuba, Thailand, Saudi Arabia and Argentina
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Farnot Ubaldo, Carroli Guillermo, Ba'aqeel Hassan, Al-Mazrou Yagob, Garcia Jo, Villar José, Al-Osimy Muneera, Rojas Georgina, Romero Mariana, Kuchaisit Chusri, Langer Ana, Nigenda Gustavo, Lumbiganon Pisake, Belizán José, Bergsjo Per, Bakketeig Leiv, and Lindmark Gunilla
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Antenatal care ,users' opinions ,qualitative data ,developing countries ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background The results of a qualitative study carried out in four developing countries (Cuba, Thailand, Saudi Arabia and Argentina) are presented. The study was conducted in the context of a randomised controlled trial to test the benefits of a new antenatal care protocol that reduced the number of visits to the doctor, rationalised the application of technology, and improved the provision of information to women in relation to the traditional protocol applied in each country. Methods Through focus groups discussions we were able to assess the concepts and expectations underlying women's evaluation of concepts and experiences of the care received in antenatal care clinics. 164 women participated in 24 focus groups discussion in all countries. Results Three areas are particularly addressed in this paper: a) concepts about pregnancy and health care, b) experience with health services and health providers, and c) opinions about the modified Antenatal Care (ANC) programme. In all three topics similarities were identified as well as particular opinions related to country specific social and cultural values. In general women have a positive view of the new ANC protocol, particularly regarding the information they receive. However, controversial issues emerged such as the reduction in the number of visits, particularly in Cuba where women are used to have 18 ANC visits in one pregnancy period. Conclusion Recommendations to improve ANC services performance are being proposed. Any country interested in the application of a new ANC protocol should regard the opinion and acceptability of women towards changes.
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- 2003
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32. Are women and providers satisfied with antenatal care? Views on a standard and a simplified, evidence-based model of care in four developing countries
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Ba'aqeel Hassan, Carroli Guillermo, Al-Mazrou Yagob, Farnot Ubaldo, Miguel Belizán José, Al-Osimi Muneera, Rojas Georgina, Kuchaisit Chusri, Piaggio Gilda, Nigenda Gustavo, Romero Mariana, Villar José, Langer Ana, Lumbiganon Pisake, Pinol Alain, Bergsjö Per, Bakketeig Leiv, Garcia Jo, and Berendes Heinz
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Gynecology and obstetrics ,RG1-991 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background This study assessed women and providers' satisfaction with a new evidence-based antenatal care (ANC) model within the WHO randomized trial conducted in four developing countries. The WHO study was a randomized controlled trial that compared a new ANC model with the standard type offered in each country. The new model of ANC emphasized actions known to be effective in improving maternal or neonatal health, excluded other interventions that have not proved to be beneficial, and improved the information component, especially alerting pregnant women to potential health problems and instructing them on appropriate responses. These activities were distributed within four antenatal care visits for women that did not need any further assessment. Methods Satisfaction was measured through a standardized questionnaire administered to a random sample of 1,600 pregnant women and another to all antenatal care providers. Results Most women in both arms expressed satisfaction with ANC. More women in the intervention arm were satisfied with information on labor, delivery, family planning, pregnancy complications and emergency procedures. More providers in the experimental clinics were worried about visit spacing, but more satisfied with the time spent and information provided. Conclusions Women and providers accepted the new ANC model generally. The safety of fewer visits for women without complications with longer spacing would have to be reinforced, if such a model is to be introduced into routine practice.
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- 2002
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33. Additional file 1: Table S1. of Maternal near miss and predictive ability of potentially life-threatening conditions at selected maternity hospitals in Latin America
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Bremen De Mucio, Abalos, Edgardo, Cuesta, Cristina, Carroli, Guillermo, Serruya, Suzanne, Giordano, Daniel, Martinez, Gerardo, Sosa, Claudio, and JoĂŁo Souza
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Participating hospitals, recruitment and coverage. Table S2. Maternal characteristics. Table S3. Potentially life threatening condition distribution among the whole population and women with SMO. (DOC 195Â kb)
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- 2016
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34. Additional file 2: of Room temperature stable carbetocin for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally: study protocol for a randomized controlled trial
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Widmer, Mariana, Piaggio, Gilda, Abdel-Aleem, Hany, Carroli, Guillermo, Yap-Seng Chong, Arri Coomarasamy, Bukola Fawole, Shivaprasad Goudar, G. Hofmeyr, Pisake Lumbiganon, Kidza Mugerwa, Nguyen, Thi, Qureshi, Zahida, Joao Souza, and A. GĂźlmezoglu
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Rationale for the choice of the non-inferiority trial the choice of the non-inferiority trial [20-22]. (DOCX 24 kb)
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- 2016
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35. Additional file 1: of Room temperature stable carbetocin for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally: study protocol for a randomized controlled trial
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Widmer, Mariana, Piaggio, Gilda, Abdel-Aleem, Hany, Carroli, Guillermo, Yap-Seng Chong, Arri Coomarasamy, Bukola Fawole, Shivaprasad Goudar, G. Hofmeyr, Pisake Lumbiganon, Kidza Mugerwa, Nguyen, Thi, Qureshi, Zahida, Joao Souza, and A. GĂźlmezoglu
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Countries ethics committees list and status of the project approval request. (DOCX 15 kb)
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- 2016
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36. Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight
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Kiserud, Torvid, primary, Piaggio, Gilda, additional, Carroli, Guillermo, additional, Widmer, Mariana, additional, Carvalho, José, additional, Neerup Jensen, Lisa, additional, Giordano, Daniel, additional, Cecatti, José Guilherme, additional, Aleem, Hany Abdel, additional, Talegawkar, Sameera A., additional, Benachi, Alexandra, additional, Diemert, Anke, additional, Kitoto, Antoinette Tshefu, additional, Thinkhamrop, Jadsada, additional, Lumbiganon, Pisake, additional, Tabor, Ann, additional, Kriplani, Alka, additional, Gonzalez, Rogelio, additional, Hecher, Kurt, additional, Hanson, Mark A., additional, Gülmezoglu, A. Metin, additional, and Platt, Lawrence D., additional
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- 2017
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37. El parto pretérmino: detección de riesgos y tratamientos preventivos
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Althabe Fernando, Carroli Guillermo, Lede Roberto, Belizán José M., and Althabe Omar H.
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lcsh:Arctic medicine. Tropical medicine ,lcsh:RC955-962 ,lcsh:Public aspects of medicine ,lcsh:R ,lcsh:Medicine ,lcsh:RA1-1270 - Abstract
Todos los años nacen en el mundo alrededor de 13 millones de niños prematuros. La mayor parte de esos niños nacen en países en desarrollo y constituyen el componente principal de la morbilidad y la mortalidad perinatales. En el presente estudio de revisión se analizaron los datos científicamente validados sobre las intervenciones que se emplean con la intención de evitar al menos una parte de los partos pretérmino y disminuir su impacto en la salud neonatal. Se consultaron las bases de datos Biblioteca Cochrane y Medline y se estudiaron 50 trabajos de revisión y artículos de investigación relacionados con el tema del parto pretérmino en sus siguientes aspectos: factores de riesgo y detección precoz del riesgo de parto pretérmino; prevención de la amenaza de parto pretérmino; tratamiento del parto pretérmino iniciado, y prevención del síndrome de dificultad respiratoria neonatal. Se encontraron pocos medios ensayados con éxito para predecir, prevenir o detectar precozmente la amenaza de parto pretérmino. Solo el tamizaje y tratamiento de la bacteriuria asintomática pueden recomendarse para todas las embarazadas como parte del control prenatal. El tamizaje de la vaginosis bacteriana y su tratamiento ulterior y el cerclaje profiláctico reducen, respectivamente, la incidencia de nacimientos adelantados en embarazadas con antecedentes de parto prematuro y en las que tienen antecedentes de más de tres partos pretérmino. Como tratamiento del parto iniciado antes de tiempo, con o sin rotura prematura de membranas, las intervenciones que han mostrado eficacia son la administración de betamiméticos a la parturienta para prolongar por 48 horas el período de latencia del parto y de indometacina con el mismo objetivo como medicamento de segunda elección. La administración prenatal de corticoides a la embarazada puede inducir la maduración pulmonar del feto y reducir el síndrome de dificultad respiratoria y la hemorragia ventricular, reduciendo así la mortalidad neonatal. Se recomienda continuar y apoyar las investigaciones básicas y epidemiológicas sobre la prevención para adquirir más conocimientos sobre las causas y mecanismos del parto pretérmino y cómo prevenir la morbilidad y mortalidad que produce.
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- 1999
38. Room temperature stable carbetocin for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally: study protocol for a randomized controlled trial
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Widmer, Mariana, primary, Piaggio, Gilda, additional, Abdel-Aleem, Hany, additional, Carroli, Guillermo, additional, Chong, Yap-Seng, additional, Coomarasamy, Arri, additional, Fawole, Bukola, additional, Goudar, Shivaprasad, additional, Hofmeyr, G. Justus, additional, Lumbiganon, Pisake, additional, Mugerwa, Kidza, additional, Nguyen, Thi My Huong, additional, Qureshi, Zahida, additional, Souza, Joao Paulo, additional, and Gülmezoglu, A. Metin, additional
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- 2016
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39. Consenso salud materna para Chile en el nuevo milenio
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González P,Rogelio, Koch C,Elard, Poblete L,José Andrés, Vera P,Claudio, Muñoz S,Hernán, Carroli,Guillermo, Abalos,Edgardo, Lalonde,André, Oyarzún E,Enrique, Germain A,Alfredo, Schnapp S,Carlos, Neira M,Jorge, Hasbun H,Jorge, Carvajal C,Jorge, Theodor D,Mónica, Vargas I,Paula, Insunza F,Álvaro, Kusanovic P,Juan, Gómez M,Ricardo, González O,Miriam, Guzmán B,Eghon, Paublo M,Mario, Burgos E,Soledad, Clavero P,Marco, and Klassen P,Francisco
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objetivos del milenio (ODMs) ,Maternal mortality in Chile ,consenso salud materna ,near miss ,políticas públicas materno-infantiles ,consensus in maternal health ,Mortalidad materna en Chile ,millennium developmental goals (MDGs) ,public policies - Abstract
Contexto: Chile presenta una tendencia secular hacia una sostenida mejoría en los principales indicadores materno-infantiles. Su situación constituye una experiencia positiva a nivel de la región de Latino-América y el Caribe. Sin embargo, esta tendencia se ha estancado en los últimos diez años lo que produce una situación inestable y preocupante desde el punto de vista de la salud pública materna. Esto motiva una reunión de expertos a nivel nacional e internacional para proponer estrategias para el alto nivel político orientadas a alcanzar los Objetivos 4 y 5 del Milenio. Conclusión: Este documento de consenso sobre mortalidad materna, sugiere un enfrentamiento en dos ejes: primero, enfrentar la nueva realidad epidemiológica desde la etapa pre-concepcional, esto incluye considerar la alta prevalencia de obesidad, hipertensión arterial, diabetes, hiperlipidemias e hipotiroidismo en la población, y por otro lado reforzar la seguridad de la asistencia del embarazo, parto y puerperio en los lugares más alejados y más vulnerables del país. Es necesario focalizar las intervenciones en los grupos de mayor riesgo vital (edades extremas de la vida fértil y portadoras de enfermedades médico-quirúrgicas severas, que se reflejan en el aumento proporcional de las causas indirectas de muerte materna), reforzar las actividades de auditorías de mortalidad/near miss, así como controlar el aumento alarmante de la tasa de partos por cesáreas. Background: Chile represents a positive evolution in terms of maternal and infant health in last fifty years. This trend in last ten years has remains stable. According to this situation a National and Regional Consensus meeting about Maternal Mortality has been organized. Conclusion: Propositions have been released about how to improve maternal and child health in Chile. Main focus might be to confront the new epidemiological reality including maternal overweight/obesity, hypertension, diabetes, hyperlipidemia and hypothyroidism. Effort must be done focusing in the day around the birth, mainly in rural and poorest areas of the country. Indirect causes of maternal mortality have become the main problems in maternal care; this fact must be reflected in protocols, audits (including near miss) and public policies. High rate of cesarean section also remains a challenged.
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- 2013
40. Maternal near miss and predictive ability of potentially life-threatening conditions at selected maternity hospitals in Latin America.
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De Mucio, Bremen, Abalos, Edgardo, Cuesta, Cristina, Carroli, Guillermo, Serruya, Suzanne, Giordano, Daniel, Martinez, Gerardo, Sosa, Claudio G., and Souza, João Paulo
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CONFIDENCE intervals ,DOCUMENTATION ,EVALUATION of medical care ,MATERNAL mortality ,MULTIVARIATE analysis ,OBSTETRICAL emergencies ,PREGNANCY ,PREGNANCY complications ,STATISTICS ,LOGISTIC regression analysis ,RESEARCH bias ,CROSS-sectional method ,RECEIVER operating characteristic curves ,DATA analysis software ,ODDS ratio - Abstract
Background: Every year millions of women around the world suffer from pregnancy, childbirth and postpartum complications. Women who survive the most serious clinical conditions are regarded as to have experienced a severe acute maternal complication called maternal near miss (MNM). Information about MNM cases may complement the data collected through the analysis of maternal death, and was proposed as a helpful tool to identify strengths and weaknesses of health systems in relation to maternal health care. The purpose of this study is to evaluate the performance of a systematized form to detect severe maternal outcomes (SMO) in 20 selected maternity hospitals from Latin America (LAC). Methods: Cross-sectional study. Data were obtained from analysis of hospital records for all women giving birth and all women who had a SMO in the selected hospitals. Univariate and multivariate adjusted logistic regression models were used to assess the predictive ability of different conditions to identify SMO cases. In parallel, external auditors were hired for reviewing and reporting the total number of discharges during the study period, in order to verify whether health professionals at health facilities identified all MNM and Potentially life-threatening condition (PLTC) cases. Results: Twenty hospitals from twelve LAC were initially included in the study and based on the level of coverage, 11 hospitals with a total of 3,196 records were included for the final analysis. The incidence of SMO and MNM outcomes was 12.9 and 12.3 per 1,000 live births, respectively. The ratio of MNM to maternal death was 19 to 1, with a mortality index of 5.1%. Both univariate and multivariate analysis showed a good performance for a number of clinical and laboratory conditions to predict a severe maternal outcome, however, their clinical relevance remains to be confirmed. Coherence between health professionals and external auditors to identify SMO was high (around 100 %). Conclusions: The form tested, was well accepted by health professionals and was capable of identifying 100 % of MNM cases and more than 99 % of PLTC variables. Altered state of consciousness, oliguria, placenta accrete, pulmonary edema, and admission to Intensive Care Unit have a high (LR+ ≥80) capacity to anticipate a SMO. [ABSTRACT FROM AUTHOR]
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- 2016
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41. ESTADO ACTUAL DE LA MEDICINA BASADA EN LA EVIDENCIA.
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CARROLI, GUILLERMO
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- 2019
42. Maternal and perinatal health research priorities beyond 2015: an international survey and prioritization exercise
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Souza, Joao Paulo, primary, Widmer, Mariana, additional, Gülmezoglu, Ahmet Metin, additional, Lawrie, Theresa Anne, additional, Adejuyigbe, Ebunoluwa Aderonke, additional, Carroli, Guillermo, additional, Crowther, Caroline, additional, Currie, Sheena M, additional, Dowswell, Therese, additional, Hofmeyr, Justus, additional, Lavender, Tina, additional, Lawn, Joy, additional, Mader, Silke, additional, Martinez, Francisco Eulógio, additional, Mugerwa, Kidza, additional, Qureshi, Zahida, additional, Silvestre, Maria Asuncion, additional, Soltani, Hora, additional, Torloni, Maria Regina, additional, Tsigas, Eleni Z, additional, Vowles, Zoe, additional, Ouedraogo, Léopold, additional, Serruya, Suzanne, additional, Al-Raiby, Jamela, additional, Awin, Narimah, additional, Obara, Hiromi, additional, Mathai, Matthews, additional, Bahl, Rajiv, additional, Martines, José, additional, Ganatra, Bela, additional, Phillips, Sharon Jelena, additional, Johnson, Brooke Ronald, additional, Vogel, Joshua P, additional, Oladapo, Olufemi T, additional, and Temmerman, Marleen, additional
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- 2014
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43. WHO multicentre study for the development of growth standards from fetal life to childhood: the fetal component
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Merialdi, Mario, primary, Widmer, Mariana, additional, Gülmezoglu, Ahmet Metin, additional, Abdel-Aleem, Hany, additional, Bega, George, additional, Benachi, Alexandra, additional, Carroli, Guillermo, additional, Cecatti, Jose Guilherme, additional, Diemert, Anke, additional, Gonzalez, Rogelio, additional, Hecher, Kurt, additional, Jensen, Lisa N, additional, Johnsen, Synnøve L, additional, Kiserud, Torvid, additional, Kriplani, Alka, additional, Lumbiganon, Pisake, additional, Tabor, Ann, additional, Talegawkar, Sameera A, additional, Tshefu, Antoinette, additional, Wojdyla, Daniel, additional, and Platt, Lawrence, additional
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- 2014
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44. Outcomes of non-vertex second twins, following vertex vaginal delivery of first twin: a secondary analysis of the WHO Global Survey on Maternal and Perinatal Health
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Vogel, Joshua P, primary, Holloway, Erica, additional, Cuesta, Cristina, additional, Carroli, Guillermo, additional, Souza, João Paulo, additional, and Barrett, Jon, additional
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- 2014
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45. Antenatal care packages with reduced visits and perinatal mortality: a secondary analysis of the WHO Antenatal Care Trial
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Vogel, Joshua P, primary, Habib, Ndema Abu, additional, Souza, João Paulo, additional, Gülmezoglu, A Metin, additional, Dowswell, Therese, additional, Carroli, Guillermo, additional, Baaqeel, Hassan S, additional, Lumbiganon, Pisake, additional, Piaggio, Gilda, additional, and Oladapo, Olufemi T, additional
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- 2013
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46. A cluster randomized controlled trial to evaluate the effectiveness of the clinically integrated RHL evidence -based medicine course
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Kulier, Regina, primary, Khan, Khalid S, additional, Gulmezoglu, A Metin, additional, Carroli, Guillermo, additional, Cecatti, Jose G, additional, Germar, Maria J, additional, Lumbiganon, Pisake, additional, Mittal, Suneeta, additional, Pattinson, Robert, additional, Wolomby-Molondo, Jean-Jose, additional, Bergh, Anne-Marie, additional, and May, Win, additional
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- 2010
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47. Maternal near miss and maternal death in the 2005 WHO global survey on maternal and perinatal health
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Souza, Joao Paulo, primary, Cecatti, Jose Guilherme, additional, Faundes, Anibal, additional, Morais, Sirlei Siani, additional, Villar, Jose, additional, Carroli, Guillermo, additional, Gulmezoglu, Metin, additional, Wojdyla, Daniel, additional, Zavaleta, Nelly, additional, Donner, Allan, additional, Velazco, Alejandro, additional, Bataglia, Vicente, additional, Valladares, Eliette, additional, Kublickas, Marius, additional, and Acosta, Arnaldo, additional
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- 2010
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48. WHO Global Survey on Maternal and Perinatal Health in Latin America: classifying caesarean sections
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Betrán, Ana P, primary, Gulmezoglu, A Metin, additional, Robson, Michael, additional, Merialdi, Mario, additional, Souza, João P, additional, Wojdyla, Daniel, additional, Widmer, Mariana, additional, Carroli, Guillermo, additional, Torloni, Maria R, additional, Langer, Ana, additional, Narváez, Alberto, additional, Velasco, Alejandro, additional, Faúndes, Anibal, additional, Acosta, Arnaldo, additional, Valladares, Eliette, additional, Romero, Mariana, additional, Zavaleta, Nelly, additional, Reynoso, Sofia, additional, and Bataglia, Vicente, additional
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- 2009
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49. Active management of the third stage of labour without controlled cord traction: a randomized non-inferiority controlled trial
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Gülmezoglu, A Metin, primary, Widmer, Mariana, additional, Merialdi, Mario, additional, Qureshi, Zahida, additional, Piaggio, Gilda, additional, Elbourne, Diana, additional, Abdel-Aleem, Hany, additional, Carroli, Guillermo, additional, Hofmeyr, G Justus, additional, Lumbiganon, Pisake, additional, Derman, Richard, additional, Okong, Pius, additional, Goudar, Shivaprasad, additional, Festin, Mario, additional, Althabe, Fernando, additional, and Armbruster, Deborah, additional
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- 2009
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50. Varicella Seroprevalence and Molecular Epidemiology of Varicella-Zoster Virus in Argentina, 2002
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Dayan, Gustavo H., primary, Panero, María S., additional, Debbag, Roberto, additional, Urquiza, Ana, additional, Molina, Marta, additional, Prieto, Susana, additional, del Carmen Perego, María, additional, Scagliotti, Graciela, additional, Galimberti, Diana, additional, Carroli, Guillermo, additional, Wolff, Cristina, additional, Schmid, D. Scott, additional, Loparev, Vladimir, additional, Guris, Dalya, additional, and Seward, Jane, additional
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- 2004
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