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1. Bacille Calmette-Guérin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial

Author

Curtis, Nigel, Davidson, Andrew, Gardiner, Kaya, Gwee, Amanda, Jamieson, Tenaya, Messina, Nicole, Morawakage, Thilanka, Perlen, Susan, Perrett, Kirsten, Pittet, Laure, Sastry, Amber, Teo, Jia Wei, Orsini, Francesca, Lee, Katherine, Moore, Cecilia, Vidmar, Suzanna, PITTET, Laure, Ali, Rashida, Dunn, Ross, Edler, Peta, Gell, Grace, Goodall, Casey, Hall, Richard, Krastev, Ann, La, Nathan, McDonald, Ellie, McPhate, Nick, Nguyen, Thao, Ren, Jack, Stevens, Luke, Alamrousi, Ahmed, Bonnici, Rhian, Dang, Thanh, Germano, Susie, Hua, Jenny, McElroy, Rebecca, Razmovska, Monica, Reddiex, Scott, Wang, Xiaofang, Anderson, Jeremy, Azzopardi, Kristy, Bennett-Wood, Vicki, Czajko, Anna, Mazarakis, Nadia, McCafferty, Conor, Oppedisano, Frances, Ortika, Belinda, Pell, Casey, Spry, Leena, Toh, Ryan, Velagapudi, Sunitha, Vlahos, Amanda, Wee-Hee, Ashleigh, Ramos, Pedro, De La Cruz, Karina, Gamage, Dinusha, Karunanayake, Anushka, Mezzetti, Isabella, Ong, Benjamin, Singh, Ronita, Sooriyarachchi, Enoshini, Nicholson, Suellen, Cain, Natalie, Brizuela, Rianne, Huang, Han, Abruzzo, Veronica, Bealing, Morgan, Bimboese, Patricia, Bowes, Kirsty, Burrell, Emma, Chan, Joyce, Cushnahan, Jac, Elborough, Hannah, Elkington, Olivia, Fahey, Kieran, Fernandez, Monique, Flynn, Catherine, Fowler, Sarah, Andrit, Marie Gentile, Gladanac, Bojana, Hammond, Catherine, Ma, Norine, Macalister, Sam, Milojevic, Emmah, Mojeed, Jesutofunmi, Nguyen, Jill, O'Donnell, Liz, Olivier, Nadia, Ooi, Isabelle, Reynolds, Stephanie, Shen, Lisa, Sherry, Barb, Spotswood, Judith, Wedderburn, Jamie, Younes, Angela, Legge, Donna, Bell, Jason, Cheah, Jo, Cobbledick, Annie, Lim, Kee, Elia, Sonja, Addlem, Lynne, Bourke, Anna, Brophy, Clare, Henare, Nadine, Jenkins, Narelle, Machingaifa, Francesca, Miller, Skye, Mitchell, Kirsten, Pitkin, Sigrid, Wall, Kate, Villanueva, Paola, Crawford, Nigel, Norton, Wendy, Tan, Niki, Chengodu, Thilakavathi, Dawson, Diane, Gordon, Victoria, Korman, Tony, O'Bryan, Jess, Agius, Sophie, Bannister, Samantha, Bucholc, Jess, Burns, Alison, Camesella, Beatriz, Carlin, John, Ciaverella, Marianna, Curtis, Maxwell, Firth, Stephanie, Guo, Christina, Hannan, Matthew, Hill, Erin, Joshi, Sri, Lieschke, Katherine, Mathers, Megan, Odoi, Sasha, Rak, Ashleigh, Richards, Chris, Steve, Leah, Stewart, Carolyn, Sudbury, Eva, Thomson, Helen, Watts, Emma, Williams, Fiona, Young, Angela, Glenn, Penny, Kaynes, Andrew, De Floy, Amandine Philippart, Buchanan, Sandy, Sondag, Thijs, Xie, Ivy, Edmund, Harriet, Byrne, Bridie, Keeble, Tom, Ngien, Belle, Noonan, Fran, Wearing-Smith, Michelle, Clarke, Alison, Davies, Pemma, Eastwood, Oliver, Ellinghaus, Alric, Ghieh, Rachid, Hilton, Zahra, Jennings, Emma, Kakkos, Athina, Liang, Iris, Nicol, Katie, O'Callaghan, Sally, Osman, Helen, Rajaram, Gowri, Ratcliffe, Sophia, Rayner, Victoria, Salmon, Ashleigh, Scheppokat, Angela, Stevens, Aimee, Street, Rebekah, Toogood, Nicholas, Wood, Nicholas, Bahaduri, Twinkle, Baulman, Therese, Byrne, Jennifer, Carter, Candace, Corbett, Mary, Dao, Aiken, Desylva, Maria, Dunn, Andrew, Gardiner, Evangeline, Joyce, Rosemary, Kandasamy, Rama, Munns, Craig, Pelayo, Lisa, Sharma, Ketaki, Sterling, Katrina, Uren, Caitlin, Colaco, Clinton, Douglas, Mark, Hamilton, Kate, Bartlett, Adam, McMullan, Brendan, Palasanthiran, Pamela, Williams, Phoebe, Beardsley, Justin, Bergant, Nikki, Lagunday, Renier, Overton, Kristen, Post, Jeffrey, Al-Hindawi, Yasmeen, Barney, Sarah, Byrne, Anthony, Mead, Lee, Plit, Marshall, Lynn, David, Benson, Saoirse, Blake, Stephen, Botten, Rochelle, Chern, Tee Yee, Eden, Georgina, Griffith, Liddy, James, Jane, Lynn, Miriam, Markow, Angela, Sacca, Domenic, Stevens, Natalie, Wesselingh, Steve, Doran, Catriona, Barry, Simone, Sawka, Alice, Evans, Sue, Goodchild, Louise, Heath, Christine, Krieg, Meredith, Marshall, Helen, McMillan, Mark, Walker, Mary, Richmond, Peter, Amenyogbe, Nelly, Anthony, Christina, Arnold, Annabelle, Arrowsmith, Beth, Ben-Othman, Rym, Clark, Sharon, Dunnill, Jemma, Eiffler, Nat, Ewe, Krist, Finucane, Carolyn, Flynn, Lorraine, Gibson, Camille, Hartnell, Lucy, Hollams, Elysia, Hutton, Heidi, Jarvis, Lance, Jones, Jane, Jones, Jan, Jones, Karen, Kent, Jennifer, Kollmann, Tobias, Lalich, Debbie, Lee, Wenna, Lim, Rachel, McAlister, Sonia, McDonald, Fiona, Meehan, Andrea, Minhaj, Asma, Montgomery, Lisa, O'Donnell, Melissa, Ong, Jaslyn, Ong, Joanne, Parkin, Kimberley, Perez, Glady, Power, Catherine, Rezazadeh, Shadie, Richmond, Holly, Rogers, Sally, Schultz, Nikki, Shave, Margaret, Skut, Patrycja, Stiglmayer, Lisa, Truelove, Alexandra, Wadia, Ushma, Wallace, Rachael, Waring, Justin, England, Michelle, Latkovic, Erin, Manning, Laurens, Herrmann, Susan, Lucas, Michaela, Lacerda, Marcus, Andrade, Paulo Henrique, Barbosa, Fabiane Bianca, Barros, Dayanne, Brasil, Larissa, Capella, Ana Greyce, Castro, Ramon, Costa, Erlane, de Souza, Dilcimar, Dias, Maianne, Dias, José, Ferreira, Klenilson, Figueiredo, Paula, Freitas, Thamires, Furtado, Ana Carolina, Gama, Larissa, Godinho, Vanessa, Gouy, Cintia, Hinojosa, Daniele, Jardim, Bruno, Jardim, Tyane, Junior, Joel, Lima, Augustto, Maia, Bernardo, Marins, Adriana, Mazurega, Kelry, Medeiros, Tercilene, Melo, Rosangela, Moraes, Marinete, Nascimento, Elizandra, Neves, Juliana, Oliveira, Maria Gabriela, Oliveira, Thais, Oliveira, Ingrid, Otsuka, Arthur, Paes, Rayssa, Pereira, Handerson, Pereira, Gabrielle, Prado, Christiane, Queiroz, Evelyn, Rodrigues, Laleyska, Rodrigues, Bebeto, Sampaio, Vanderson, Santos, Anna Gabriela, Santos, Daniel, Santos, Tilza, Santos, Evelyn, Sartim, Ariandra, Silva, Ana Beatriz, Silva, Juliana, Silva, Emanuelle, Simão, Mariana, Soares, Caroline, Sousa, Antonny, Trindade, Alexandre, Val, Fernando, Vasconcelos, Adria, Vasconcelos, Heline, Croda, Julio, Abreu, Carolinne, Almeida, Katya Martinez, Bitencourt de Andrade, Camila, Campos Angelo, Jhenyfer Thalyta, Gonçalvez de Araújo Arcanjo, Ghislaine, Silva Menezes Arruda, Bianca Maria, Ayala, Wellyngthon Espindola, Refosco Barbosa, Adelita Agripina, Vieira Batista, Felipe Zampieri, de Morais Batista, Fabiani, de Jesus Costa, Miriam, Croda, Mariana Garcia, Alves da Cruz, Lais, Pereira Diogo, Roberta Carolina, Dutra Escobar, Rodrigo Cezar, Fernandes, Iara Rodrigues, Figueiredo, Leticia Ramires, Cavalcanti Gonçalves, Leandro Galdino, Lahdo, Sarita, Lencina, Joyce dos Santos, Teodoro de Lima, Guilherme, LEOPOLDINA MEIRELES, Bruna Tayara, Moreira, Debora Quadros, Silva Muranaka, Lilian Batista, de Oliveira, Adriely, Warszawski de Oliveira, Karla Regina, Vieira de Oliveira, Matheus, Dias de Oliveira, Roberto, Pereira, Andrea Antonia Souza de Almeida dos Reis, Puga, Marco, Ramos, Caroliny Veron, Souza da Rosa, Thaynara Haynara, Lopes dos Santos, Karla, Ribeiro dos Santos, Claudinalva, Leopoldina dos Santos, Dyenyffer Stéffany, Santos, Karina Marques, Pereira da Silva, Paulo César, Rocha da Silva, Paulo Victor, Silva, Débora dos Santos, Vieira da Silva, Patricia, Freitas da Rosa Soares, Bruno, Sperotto, Mariana Gazzoni, Tadokoro, Mariana Mayumi, Tsuha, Daniel, Ramos Vieira, Hugo Miguel, Pretti Dalcolmo, Margareth Maria, Lopes Alves da Paixão, Cíntia Maria, Corrêa E Castro, Gabriela, Collopy, Simone Silva, da Costa Silva, Renato, Almeida da Silveira, Samyra, Da-Cruz, Alda Maria, Maria da Silva Passos de Carvalho, Alessandra, de Cássia Batista, Rita, Silva De Freitas, Maria Luciana, Gerhardt de Oliveira Ferreira, Aline, Conceição de Souza, Ana Paula, Doblas, Paola Cerbino, Alcoforado da Silva dos Santos, Ayla, Cristine de Moraes dos Santos, Vanessa, Alves dos Santos Gomes, Dayane, Fortunato, Anderson Lage, Gomes-Silva, Adriano, Gonçalves, Monique Pinto, Garcia Meireless Junior, Paulo Leandro, Martins da Costa Carvalho, Estela, Motta, Fernando do Couto, Olivo de Mendonça, Ligia Maria, Pandine, Girlene dos Santos, Plácido Pereira, Rosa Maria, Maia, Ivan Ramos, Luiz da Rocha, Jorge, Paiva Romano, João Victor, Santos, Glauce dos, Fernandes da Silva, Erica, Mendonça Teixeira de Siqueira, Marilda Agudo, Prudêncio Soares, Ágatha Cristinne, Bonten, Marc, Arroyo, Sandra Franch, Besten, Henny Ophorst-den, Boon, Anna, Brakke, Karin M., Janssen, Axel, Koopmans, Marijke A.H., Lemmens, Toos, Leurink, Titia, Prat-Aymerich, Cristina, Septer-Bijleveld, Engelien, Stadhouders, Kimberly, Troeman, Darren, van der Waal, Marije, van Opdorp, Marjoleine, van Sluis, Nicolette, Wolters, Beatrijs, Kluytmans, Jan, Romme, Jannie, van den Bijllaardt, Wouter, van Mook, Linda, Rijen, M.M.L (Miranda) van, Filius, P.M.G., Gisolf, Jet, Greven, Frances, Huijbens, Danique, Hassing, Robert Jan, Pon, R.C., Preijers, Lieke, van Leusen, J.H., Verheij, Harald, Boersma, Wim, Brans, Evelien, Kloeg, Paul, Molenaar-Groot, Kitty, Nguyen, Nhat Khanh, Paternotte, Nienke, Rol, Anke, Stooper, Lida, Dijkstra, Helga, Eggenhuizen, Esther, Huijs, Lucas, Moorlag, Simone, Netea, Mihai, Pranger, Eva, Taks, Esther, Oever, Jaap ten, Heine, Rob ter, Blauwendraat, Kitty, Meek, Bob, Erkaya, Isil, Harbech, Houda, Roescher, Nienke, Peeters, Rifka, Riele, Menno te, Zhou, Carmen, Calbo, Esther, Marti, Cristina Badia, Palomares, Emma Triviño, Porcuna, Tomás Perez, Barriocanal, Anabel, Barriocanal, Ana Maria, Casas, Irma, Dominguez, Jose, Esteve, Maria, Lacoma, Alicia, Latorre, Irene, Molina, Gemma, Molina, Barbara, Rosell, Antoni, Vidal, Sandra, Barrera, Lydia, Bustos, Natalia, Calderón, Ines Portillo, Campos, David Gutierrez, Carretero, Jose Manuel, Castellano, Angel Dominguez, Compagnone, Renato, Ramirez de Arellano, Encarnacion, Serna, Almudena de la, del Toro Lopez, Maria Dolores, Clement Espindola, Marie-Alix, Martin Gutierrez, Ana Belen, Hernandez, Alvaro Pascual, Jiménez, Virginia Palomo, Moreno, Elisa, Navarrete, Nicolas, Paño, Teresa Rodriguez, Rodríguez-Baño, Jesús, Tristán, Enriqueta, Rios Villegas, Maria Jose, Garces, Atsegiñe Canga, Amo, Erika Castro, Guerrero, Raquel Coya, Goikoetxea, Josune, Jorge, Leticia, Perez, Cristina, Fariñas Álvarez, María Carmen, Cuadra, Manuel Gutierrez, Arnaiz de las Revillas Almajano, Francisco, Garcia, Pilar Bohedo, Poderos, Teresa Giménez, Rico, Claudia González, Sanchez, Blanca, Valero, Olga, Vega, Noelia, Campbell, John, Barnes, Anna, Catterick, Helen, Cranston, Tim, Dawe, Phoebe, Fletcher, Emily, Fouracre, Liam, Gifford, Alison, Gow, Neil, Kirkwood, John, Martin, Christopher, McAnew, Amy, Mitchell, Marcus, Newman, Georgina, O'Connell, Abby, Onysk, Jakob, Quinn, Lynne, Rhodes, Shelley, Stone, Samuel, Symons, Lorrie, Tripp, Harry, Watkins, Darcy, Whale, Bethany, Harding, Alex, Lockhart, Gemma, Sidaway-Lee, Kate, Hilton, Sam, Manton, Sarah, Webber-Rookes, Daniel, Winder, Rachel, Moore, James, Bateman, Freya, Gibbons, Michael, Knight, Bridget, Moss, Julie, Statton, Sarah, Studham, Josephine, Hall, Lydia, Moyle, Will, Venton, Tamsin, Pittet, Laure F., Messina, Nicole L., Croda, Mariana G., Dalcolmo, Margareth, Lacerda, Marcus V.G., Lynn, David J., Perrett, Kirsten P., Post, Jeffrey J., Richmond, Peter C., Rocha, Jorge L., Rodriguez-Baño, Jesus, Warris, Adilia, and Wood, Nicholas J.

Published
2024
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2. Specific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines—an exploratory sub-study of the BRACE trial

Author

Curtis, Nigel, Davidson, Andrew, Gardiner, Kaya, Gwee, Amanda, Jamieson, Tenaya, Messina, Nicole, Morawakage, Thilanka, Perlen, Susan, Perrett, Kirsten, Pittet, Laure, Sastry, Amber, Teo, Jia Wei, Orsini, Francesca, Lee, Katherine, Moore, Cecilia, Vidmar, Suzanna, Ali, Rashida, Dunn, Ross, Edler, Peta, Gell, Grace, Goodall, Casey, Hall, Richard, Krastev, Ann, La, Nathan, McDonald, Ellie, McPhate, Nick, Nguyen, Thao, Ren, Jack, Stevens, Luke, Alamrousi, Ahmed, Bonnici, Rhian, Dang, Thanh, Germano, Susie, Hua, Jenny, McElroy, Rebecca, Razmovska, Monica, Reddiex, Scott, Wang, Xiaofang, Anderson, Jeremy, Azzopardi, Kristy, Bennett-Wood, Vicki, Czajko, Anna, Mazarakis, Nadia, McCafferty, Conor, Oppedisano, Frances, Ortika, Belinda, Pell, Casey, Spry, Leena, Toh, Ryan, Velagapudi, Sunitha, Vlahos, Amanda, Wee-Hee, Ashleigh, Ramos, Pedro, De La Cruz, Karina, Gamage, Dinusha, Karunanayake, Anushka, Mezzetti, Isabella, Ong, Benjamin, Singh, Ronita, Sooriyarachchi, Enoshini, Nicholson, Suellen, Cain, Natalie, Brizuela, Rianne, Huang, Han, Abruzzo, Veronica, Bealing, Morgan, Bimboese, Patricia, Bowes, Kirsty, Burrell, Emma, Chan, Joyce, Cushnahan, Jac, Elborough, Hannah, Elkington, Olivia, Fahey, Kieran, Fernandez, Monique, Flynn, Catherine, Fowler, Sarah, Andrit, Marie Gentile, Gladanac, Bojana, Hammond, Catherine, Ma, Norine, Macalister, Sam, Milojevic, Emmah, Mojeed, Jesutofunmi, Nguyen, Jill, O’Donnell, Liz, Olivier, Nadia, Ooi, Isabelle, Reynolds, Stephanie, Shen, Lisa, Sherry, Barb, Spotswood, Judith, Wedderburn, Jamie, Younes, Angela, Legge, Donna, Bell, Jason, Cheah, Jo, Cobbledick, Annie, Lim, Kee, Elia, Sonja, Addlem, Lynne, Bourke, Anna, Brophy, Clare, Henare, Nadine, Jenkins, Narelle, Machingaifa, Francesca, Miller, Skye, Mitchell, Kirsten, Pitkin, Sigrid, Wall, Kate, Villanueva, Paola, Crawford, Nigel, Norton, Wendy, Tan, Niki, Chengodu, Thilakavathi, Dawson, Diane, Gordon, Victoria, Korman, Tony, O’Bryan, Jess, Agius, Sophie, Bannister, Samantha, Bucholc, Jess, Burns, Alison, Camesella, Beatriz, Carlin, John, Ciaverella, Marianna, Curtis, Maxwell, Firth, Stephanie, Guo, Christina, Hannan, Matthew, Hill, Erin, Joshi, Sri, Lieschke, Katherine, Mathers, Megan, Odoi, Sasha, Rak, Ashleigh, Richards, Chris, Steve, Leah, Stewart, Carolyn, Sudbury, Eva, Thomson, Helen, Watts, Emma, Williams, Fiona, Young, Angela, Glenn, Penny, Kaynes, Andrew, De Floy, Amandine Philippart, Buchanan, Sandy, Sondag, Thijs, Xie, Ivy, Edmund, Harriet, Byrne, Bridie, Keeble, Tom, Ngien, Belle, Noonan, Fran, Wearing-Smith, Michelle, Clarke, Alison, Davies, Pemma, Eastwood, Oliver, Ellinghaus, Alric, Ghieh, Rachid, Hilton, Zahra, Jennings, Emma, Kakkos, Athina, Liang, Iris, Nicol, Katie, O’Callaghan, Sally, Osman, Helen, Rajaram, Gowri, Ratcliffe, Sophia, Rayner, Victoria, Salmon, Ashleigh, Scheppokat, Angela, Stevens, Aimee, Street, Rebekah, Toogood, Nicholas, Wood, Nicholas, Bahaduri, Twinkle, Baulman, Therese, Byrne, Jennifer, Carter, Candace, Corbett, Mary, Dao, Aiken, Desylva, Maria, Dunn, Andrew, Gardiner, Evangeline, Joyce, Rosemary, Kandasamy, Rama, Munns, Craig, Pelayo, Lisa, Sharma, Ketaki, Sterling, Katrina, Uren, Caitlin, Colaco, Clinton, Douglas, Mark, Hamilton, Kate, Bartlett, Adam, McMullan, Brendan, Palasanthiran, Pamela, Williams, Phoebe, Beardsley, Justin, Bergant, Nikki, Lagunday, Renier, Overton, Kristen, Post, Jeffrey, Al-Hindawi, Yasmeen, Barney, Sarah, Byrne, Anthony, Mead, Lee, Plit, Marshall, Lynn, David, Benson, Saoirse, Blake, Stephen, Botten, Rochelle, Chern, Tee Yee, Eden, Georgina, Griffith, Liddy, James, Jane, Lynn, Miriam, Markow, Angela, Sacca, Domenic, Stevens, Natalie, Wesselingh, Steve, Doran, Catriona, Barry, Simone, Sawka, Alice, Evans, Sue, Goodchild, Louise, Heath, Christine, Krieg, Meredith, Marshall, Helen, McMillan, Mark, Walker, Mary, Richmond, Peter, Amenyogbe, Nelly, Anthony, Christina, Arnold, Annabelle, Arrowsmith, Beth, Ben-Othman, Rym, Clark, Sharon, Dunnill, Jemma, Eiffler, Nat, Ewe, Krist, Finucane, Carolyn, Flynn, Lorraine, Gibson, Camille, Hartnell, Lucy, Hollams, Elysia, Hutton, Heidi, Jarvis, Lance, Jones, Jane, Jones, Jan, Jones, Karen, Kent, Jennifer, Kollmann, Tobias, Lalich, Debbie, Lee, Wenna, Lim, Rachel, McAlister, Sonia, McDonald, Fiona, Meehan, Andrea, Minhaj, Asma, Montgomery, Lisa, O’Donnell, Melissa, Ong, Jaslyn, Ong, Joanne, Parkin, Kimberley, Perez, Glady, Power, Catherine, Rezazadeh, Shadie, Richmond, Holly, Rogers, Sally, Schultz, Nikki, Shave, Margaret, Skut, Patrycja, Stiglmayer, Lisa, Truelove, Alexandra, Wadia, Ushma, Wallace, Rachael, Waring, Justin, England, Michelle, Latkovic, Erin, Manning, Laurens, Herrmann, Susan, Lucas, Michaela, Lacerda, Marcus, Andrade, Paulo Henrique, Barbosa, Fabiane Bianca, Barros, Dayanne, Brasil, Larissa, Capella, Ana Greyce, Castro, Ramon, Costa, Erlane, de Souza, Dilcimar, Dias, Maianne, Dias, José, Ferreira, Klenilson, Figueiredo, Paula, Freitas, Thamires, Furtado, Ana Carolina, Gama, Larissa, Godinho, Vanessa, Gouy, Cintia, Hinojosa, Daniele, Jardim, Bruno, Jardim, Tyane, Junior, Joel, Lima, Augustto, Maia, Bernardo, Marins, Adriana, Mazurega, Kelry, Medeiros, Tercilene, Melo, Rosangela, Moraes, Marinete, Nascimento, Elizandra, Neves, Juliana, Oliveira, Maria Gabriela, Oliveira, Thais, Oliveira, Ingrid, Otsuka, Arthur, Paes, Rayssa, Pereira, Handerson, Pereira, Gabrielle, Prado, Christiane, Queiroz, Evelyn, Rodrigues, Laleyska, Rodrigues, Bebeto, Sampaio, Vanderson, Santos, Anna Gabriela, Santos, Daniel, Santos, Tilza, Santos, Evelyn, Sartim, Ariandra, Silva, Ana Beatriz, Silva, Juliana, Silva, Emanuelle, Simão, Mariana, Soares, Caroline, Sousa, Antonny, Trindade, Alexandre, Val, Fernando, Vasconcelos, Adria, Vasconcelos, Heline, Croda, Julio, Abreu, Carolinne, Almeida, Katya Martinez, Bitencourt de Andrade, Camila, Campos Angelo, Jhenyfer Thalyta, Gonçalvez de Araújo Arcanjo, Ghislaine, Silva Menezes Arruda, Bianca Maria, Ayala, Wellyngthon Espindola, Refosco Barbosa, Adelita Agripina, Vieira Batista, Felipe Zampieri, de Morais Batista, Fabiani, de Jesus Costa, Miriam, Croda, Mariana Garcia, Alves da Cruz, Lais, Pereira Diogo, Roberta Carolina, Dutra Escobar, Rodrigo Cezar, Fernandes, Iara Rodrigues, Figueiredo, Leticia Ramires, Cavalcanti Gonçalves, Leandro Galdino, Lahdo, Sarita, Lencina, Joyce dos Santos, Teodoro de Lima, Guilherme, Matos, Larissa Santos, Leopoldina Meireles, Bruna Tayara, Moreira, Debora Quadros, Silva Muranaka, Lilian Batista, de Oliveira, Adriely, Warszawski de Oliveira, Karla Regina, Vieira de Oliveira, Matheus, Dias de Oliveira, Roberto, Souza de Almeida dos Reis Pereira, Andrea Antonia, Puga, Marco, Ramos, Caroliny Veron, Souza da Rosa, Thaynara Haynara, Lopes dos Santos, Karla, Ribeiro dos Santos, Claudinalva, Leopoldina dos Santos, Dyenyffer Stéffany, Santos, Karina Marques, Pereira da Silva, Paulo César, Rocha da Silva, Paulo Victor, Silva, Débora dos Santos, Vieira da Silva, Patricia, Freitas da Rosa Soares, Bruno, Sperotto, Mariana Gazzoni, Tadokoro, Mariana Mayumi, Tsuha, Daniel, Ramos Vieira, Hugo Miguel, Pretti Dalcolmo, Margareth Maria, Lopes Alves da Paixão, Cíntia Maria, Corrêa E Castro, Gabriela, Collopy, Simone Silva, da Costa Silva, Renato, Almeida da Silveira, Samyra, Da-Cruz, Alda Maria, Maria da Silva Passos de Carvalho, Alessandra, de Cássia Batista, Rita, Silva De Freitas, Maria Luciana, Gerhardt de Oliveira Ferreira, Aline, Conceição de Souza, Ana Paula, Doblas, Paola Cerbino, Alcoforado da Silva dos Santos, Ayla, Cristine de Moraes dos Santos, Vanessa, Alves dos Santos Gomes, Dayane, Fortunato, Anderson Lage, Gomes-Silva, Adriano, Gonçalves, Monique Pinto, Garcia Meireless Junior, Paulo Leandro, Martins da Costa Carvalho, Estela, Motta, Fernando do Couto, Olivo de Mendonça, Ligia Maria, Pandine, Girlene dos Santos, Plácido Pereira, Rosa Maria, Maia, Ivan Ramos, Luiz da Rocha, Jorge, Paiva Romano, João Victor, Santos, Glauce dos, Fernandes da Silva, Erica, Mendonça Teixeira de Siqueira, Marilda Agudo, Prudêncio Soares, Ágatha Cristinne, Bonten, Marc, Arroyo, Sandra Franch, Besten, Henny Ophorst-den, Boon, Anna, Brakke, Karin M., Janssen, Axel, Koopmans, Marijke A.H., Lemmens, Toos, Leurink, Titia, Prat-Aymerich, Cristina, Septer-Bijleveld, Engelien, Stadhouders, Kimberly, Troeman, Darren, van der Waal, Marije, van Opdorp, Marjoleine, van Sluis, Nicolette, Wolters, Beatrijs, Kluytmans, Jan, Romme, Jannie, van den Bijllaardt, Wouter, van Mook, Linda, Rijen, M.M.L (Miranda) van, Filius, Margreet, Gisolf, Jet, Greven, Frances, Huijbens, Danique, Hassing, Robert Jan, Pon, Roos, Preijers, Lieke, van Leusen, Joke, Verheij, Harald, Boersma, Wim, Brans, Evelien, Kloeg, Paul, Molenaar-Groot, Kitty, Nguyen, Nhat Khanh, Paternotte, Nienke, Rol, Anke, Stooper, Lida, Dijkstra, Helga, Eggenhuizen, Esther, Huijs, Lucas, Moorlag, Simone, Netea, Mihai, Pranger, Eva, Taks, Esther, Oever, Jaap ten, Heine, Rob ter, Blauwendraat, Kitty, Meek, Bob, Erkaya, Isil, Harbech, Houda, Roescher, Nienke, Peeters, Rifka, Riele, Menno te, Zhou, Carmen, Calbo, Esther, Marti, Cristina Badia, Palomares, Emma Triviño, Porcuna, Tomás Perez, Barriocanal, Anabel, Barriocanal, Ana Maria, Casas, Irma, Dominguez, Jose, Esteve, Maria, Lacoma, Alicia, Latorre, Irene, Molina, Gemma, Molina, Barbara, Rosell, Antoni, Vidal, Sandra, Barrera, Lydia, Bustos, Natalia, Calderón, Ines Portillo, Campos, David Gutierrez, Carretero, Jose Manuel, Castellano, Angel Dominguez, Compagnone, Renato, Ramirez de Arellano, Encarnacion, Serna, Almudena de la, Dolores del Toro Lopez, Maria, Clement Espindola, Marie-Alix, Martin Gutierrez, Ana Belen, Hernandez, Alvaro Pascual, Jiménez, Virginia Palomo, Moreno, Elisa, Navarrete, Nicolas, Paño, Teresa Rodriguez, Rodríguez-Baño, Jesús, Tristán, Enriqueta, Rios Villegas, Maria Jose, Garces, Atsegiñe Canga, Amo, Erika Castro, Guerrero, Raquel Coya, Goikoetxea, Josune, Jorge, Leticia, Perez, Cristina, Fariñas Álvarez, María Carmen, Cuadra, Manuel Gutierrez, Arnaiz de las Revillas Almajano, Francisco, Garcia, Pilar Bohedo, Poderos, Teresa Giménez, Rico, Claudia González, Sanchez, Blanca, Valero, Olga, Vega, Noelia, Campbell, John, Barnes, Anna, Catterick, Helen, Cranston, Tim, Dawe, Phoebe, Fletcher, Emily, Fouracre, Liam, Gifford, Alison, Kirkwood, John, Martin, Christopher, McAnew, Amy, Mitchell, Marcus, Newman, Georgina, O’Connell, Abby, Onysk, Jakob, Quinn, Lynne, Rhodes, Shelley, Stone, Samuel, Symons, Lorrie, Tripp, Harry, Warris, Adilia, Watkins, Darcy, Whale, Bethany, Harding, Alex, Lockhart, Gemma, Sidaway-Lee, Kate, Hilton, Sam, Manton, Sarah, Webber-Rookes, Daniel, Winder, Rachel, Moore, James, Bateman, Freya, Gibbons, Michael, Knight, Bridget, Moss, Julie, Statton, Sarah, Studham, Josephine, Hall, Lydia, Moyle, Will, Venton, Tamsin, Messina, Nicole L., Grubor-Bauk, Branka, Lynn, David J., Perrett, Kirsten P., Pittet, Laure F., Rudraraju, Rajeev, Stevens, Natalie E., and Subbarao, Kanta

Published
2024
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3. Bacillus Calmette-Guérin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial

Author

Curtis, Nigel, Davidson, Andrew, Gardiner, Kaya, Gwee, Amanda, Jamieson, Tenaya, Messina, Nicole, Morawakage, Thilanka, Perlen, Susan, Perrett, Kirsten, Pittet, Laure, Sastry, Amber, Teo, Jia Wei, Orsini, Francesca, Lee, Katherine, Moore, Cecilia, Vidmar, Suzanna, Ali, Rashida, Dunn, Ross, Edler, Peta, Gell, Grace, Goodall, Casey, Hall, Richard, Krastev, Ann, La, Nathan, McDonald, Ellie, McPhate, Nick, Nguyen, Thao, Ren, Jack, Stevens, Luke, Alamrousi, Ahmed, Bonnici, Rhian, Dang, Thanh, Germano, Susie, Hua, Jenny, McElroy, Rebecca, Razmovska, Monica, Reddiex, Scott, Wang, Xiaofang, Anderson, Jeremy, Azzopardi, Kristy, Bennett-Wood, Vicki, Czajko, Anna, Mazarakis, Nadia, McCafferty, Conor, Oppedisano, Frances, Ortika, Belinda, Pell, Casey, Spry, Leena, Toh, Ryan, Velagapudi, Sunitha, Vlahos, Amanda, Wee-Hee, Ashleigh, Ramos, Pedro, De La Cruz, Karina, Gamage, Dinusha, Karunanayake, Anushka, Mezzetti, Isabella, Ong, Benjamin, Singh, Ronita, Sooriyarachchi, Enoshini, Nicholson, Suellen, Cain, Natalie, Brizuela, Rianne, Huang, Han, Abruzzo, Veronica, Bealing, Morgan, Bimboese, Patricia, Bowes, Kirsty, Burrell, Emma, Chan, Joyce, Cushnahan, Jac, Elborough, Hannah, Elkington, Olivia, Fahey, Kieran, Fernandez, Monique, Flynn, Catherine, Fowler, Sarah, Andrit, Marie Gentile, Gladanac, Bojana, Hammond, Catherine, Ma, Norine, Macalister, Sam, Milojevic, Emmah, Mojeed, Jesutofunmi, Nguyen, Jill, O'Donnell, Liz, Olivier, Nadia, Ooi, Isabelle, Reynolds, Stephanie, Shen, Lisa, Sherry, Barb, Spotswood, Judith, Wedderburn, Jamie, Younes, Angela, Legge, Donna, Bell, Jason, Cheah, Jo, Cobbledick, Annie, Lim, Kee, Elia, Sonja, Addlem, Lynne, Bourke, Anna, Brophy, Clare, Henare, Nadine, Jenkins, Narelle, Machingaifa, Francesca, Miller, Skye, Mitchell, Kirsten, Pitkin, Sigrid, Wall, Kate, Villanueva, Paola, Crawford, Nigel, Norton, Wendy, Tan, Niki, Chengodu, Thilakavathi, Dawson, Diane, Gordon, Victoria, Korman, Tony, O'Bryan, Jess, Agius, Sophie, Bannister, Samantha, Bucholc, Jess, Burns, Alison, Camesella, Beatriz, Carlin, John, Ciaverella, Marianna, Curtis, Maxwell, Firth, Stephanie, Guo, Christina, Hannan, Matthew, Hill, Erin, Joshi, Sri, Lieschke, Katherine, Mathers, Megan, Odoi, Sasha, Rak, Ashleigh, Richards, Chris, Steve, Leah, Stewart, Carolyn, Sudbury, Eva, Thomson, Helen, Watts, Emma, Williams, Fiona, Young, Angela, Glenn, Penny, Kaynes, Andrew, Philippart De Floy, Amandine, Buchanan, Sandy, Sondag, Thijs, Xie, Ivy, Edmund, Harriet, Byrne, Bridie, Keeble, Tom, Ngien, Belle, Noonan, Fran, Wearing-Smith, Michelle, Clarke, Alison, Davies, Pemma, Eastwood, Oliver, Ellinghaus, Alric, Ghieh, Rachid, Hilton, Zahra, Jennings, Emma, Kakkos, Athina, Liang, Iris, Nicol, Katie, O'Callaghan, Sally, Osman, Helen, Rajaram, Gowri, Ratcliffe, Sophia, Rayner, Victoria, Salmon, Ashleigh, Scheppokat, Angela, Stevens, Aimee, Street, Rebekah, Toogood, Nicholas, Wood, Nicholas, Bahaduri, Twinkle, Baulman, Therese, Byrne, Jennifer, Carter, Candace, Corbett, Mary, Dao, Aiken, Desylva, Maria, Dunn, Andrew, Gardiner, Evangeline, Joyce, Rosemary, Kandasamy, Rama, Munns, Craig, Pelayo, Lisa, Sharma, Ketaki, Sterling, Katrina, Uren, Caitlin, Colaco, Clinton, Douglas, Mark, Hamilton, Kate, Bartlett, Adam, McMullan, Brendan, Palasanthiran, Pamela, Williams, Phoebe, Beardsley, Justin, Bergant, Nikki, Lagunday, Renier, Overton, Kristen, Post, Jeffrey, Al-Hindawi, Yasmeen, Barney, Sarah, Byrne, Anthony, Mead, Lee, Plit, Marshall, Lynn, David, Benson, Saoirse, Blake, Stephen, Botten, Rochelle, Chern, Tee Yee, Eden, Georgina, Griffith, Liddy, James, Jane, Lynn, Miriam, Markow, Angela, Sacca, Domenic, Stevens, Natalie, Wesselingh, Steve, Doran, Catriona, Barry, Simone, Sawka, Alice, Evans, Sue, Goodchild, Louise, Heath, Christine, Krieg, Meredith, Marshall, Helen, McMillan, Mark, Walker, Mary, Richmond, Peter, Amenyogbe, Nelly, Anthony, Christina, Arnold, Annabelle, Arrowsmith, Beth, Ben-Othman, Rym, Clark, Sharon, Dunnill, Jemma, Eiffler, Nat, Ewe, Krist, Finucane, Carolyn, Flynn, Lorraine, Gibson, Camille, Hartnell, Lucy, Hollams, Elysia, Hutton, Heidi, Jarvis, Lance, Jones, Jane, Jones, Jan, Jones, Karen, Kent, Jennifer, Kollmann, Tobias, Lalich, Debbie, Lee, Wenna, Lim, Rachel, McAlister, Sonia, McDonald, Fiona, Meehan, Andrea, Minhaj, Asma, Montgomery, Lisa, O'Donnell, Melissa, Ong, Jaslyn, Ong, Joanne, Parkin, Kimberley, Perez, Glady, Power, Catherine, Rezazadeh, Shadie, Richmond, Holly, Rogers, Sally, Schultz, Nikki, Shave, Margaret, Skut, Patrycja, Stiglmayer, Lisa, Truelove, Alexandra, Wadia, Ushma, Wallace, Rachael, Waring, Justin, England, Michelle, Latkovic, Erin, Manning, Laurens, Herrmann, Susan, Lucas, Michaela, Lacerda, Marcus, Andrade, Paulo Henrique, Barbosa, Fabiane Bianca, Barros, Dayanne, Brasil, Larissa, Capella, Ana Greyce, Castro, Ramon, Costa, Erlane, de Souza, Dilcimar, Dias, Maianne, Dias, José, Ferreira, Klenilson, Figueiredo, Paula, Freitas, Thamires, Furtado, Ana Carolina, Gama, Larissa, Godinho, Vanessa, Gouy, Cintia, Hinojosa, Daniele, Jardim, Bruno, Jardim, Tyane, Junior, Joel, Lima, Augustto, Maia, Bernardo, Marins, Adriana, Mazurega, Kelry, Medeiros, Tercilene, Melo, Rosangela, Moraes, Marinete, Nascimento, Elizandra, Neves, Juliana, Oliveira, Maria Gabriela, Oliveira, Thais, Oliveira, Ingrid, Otsuka, Arthur, Paes, Rayssa, Pereira, Handerson, Pereira, Gabrielle, Prado, Christiane, Queiroz, Evelyn, Rodrigues, Laleyska, Rodrigues, Bebeto, Sampaio, Vanderson, Santos, Anna Gabriela, Santos, Daniel, Santos, Tilza, Santos, Evelyn, Sartim, Ariandra, Silva, Ana Beatriz, Silva, Juliana, Silva, Emanuelle, Simão, Mariana, Soares, Caroline, Sousa, Antonny, Trindade, Alexandre, Val, Fernando, Vasconcelos, Adria, Vasconcelos, Heline, Croda, Julio, Abreu, Carolinne, Almeida, Katya Martinez, Bitencourt de Andrade, Camila, Campos Angelo, Jhenyfer Thalyta, Gonçalvez de Araújo Arcanjo, Ghislaine, Silva Menezes Arruda, Bianca Maria, Ayala, Wellyngthon Espindola, Refosco Barbosa, Adelita Agripina, Vieira Batista, Felipe Zampieri, de Morais Batista, Fabiani, de Jesus Costa, Miriam, Croda, Mariana Garcia, Alves da Cruz, Lais, Pereira Diogo, Roberta Carolina, Dutra Escobar, Rodrigo Cezar, Fernandes, Iara Rodrigues, Figueiredo, Leticia Ramires, Cavalcanti Gonçalves, Leandro Galdino, Lahdo, Sarita, Lencina, Joyce dos Santos, Teodoro de Lima, Guilherme, Matos, Larissa Santos, Leopoldina Meireles, Bruna Tayara, Moreira, Debora Quadros, Silva Muranaka, Lilian Batista, de Oliveira, Adriely, Warszawski de Oliveira, Karla Regina, Vieira de Oliveira, Matheus, Dias de Oliveira, Roberto, Souza de Almeida dos Reis Pereira, Andrea Antonia, Puga, Marco, Ramos, Caroliny Veron, Souza da Rosa, Thaynara Haynara, Lopes dos Santos, Karla, Ribeiro dos Santos, Claudinalva, Leopoldina dos Santos, Dyenyffer Stéffany, Santos, Karina Marques, Pereira da Silva, Paulo César, Rocha da Silva, Paulo Victor, Silva, Débora dos Santos, Vieira da Silva, Patricia, Freitas da Rosa Soares, Bruno, Sperotto, Mariana Gazzoni, Tadokoro, Mariana Mayumi, Tsuha, Daniel, Ramos Vieira, Hugo Miguel, Pretti Dalcolmo, Margareth Maria, Lopes Alves da Paixão, Cíntia Maria, Corrêa E Castro, Gabriela, Collopy, Simone Silva, da Costa Silva, Renato, Almeida da Silveira, Samyra, Da-Cruz, Alda Maria, Maria da Silva Passos de Carvalho, Alessandra, de Cássia Batista, Rita, Silva De Freitas, Maria Luciana, Gerhardt de Oliveira Ferreira, Aline, Conceição de Souza, Ana Paula, Doblas, Paola Cerbino, Alcoforado da Silva dos Santos, Ayla, Cristine de Moraes dos Santos, Vanessa, Alves dos Santos Gomes, Dayane, Fortunato, Anderson Lage, Gomes-Silva, Adriano, Gonçalves, Monique Pinto, Garcia Meireless Junior, Paulo Leandro, Martins da Costa Carvalho, Estela, Motta, Fernando do Couto, Olivo de Mendonça, Ligia Maria, Pandine, Girlene dos Santos, Plácido Pereira, Rosa Maria, Maia, Ivan Ramos, Luiz da Rocha, Jorge, Paiva Romano, João Victor, Santos, Glauce dos, Fernandes da Silva, Erica, Mendonça Teixeira de Siqueira, Marilda Agudo, Prudêncio Soares, Ágatha Cristinne, Bonten, Marc, Arroyo, Sandra Franch, Besten, Henny Ophorst-den, Boon, Anna, Brakke, Karin M., Janssen, Axel, Koopmans, Marijke A.H., Lemmens, Toos, Leurink, Titia, Prat-Aymerich, Cristina, Septer-Bijleveld, Engelien, Stadhouders, Kimberly, Troeman, Darren, van der Waal, Marije, van Opdorp, Marjoleine, van Sluis, Nicolette, Wolters, Beatrijs, Kluytmans, Jan, Romme, Jannie, van den Bijllaardt, Wouter, van Mook, Linda, Rijen, M.M.L (Miranda) van, Filius, P.M.G., Gisolf, Jet, Greven, Frances, Huijbens, Danique, Hassing, Robert Jan, Pon, R.C., Preijers, Lieke, van Leusen, J.H., Verheij, Harald, Boersma, Wim, Brans, Evelien, Kloeg, Paul, Molenaar-Groot, Kitty, Nguyen, Nhat Khanh, Paternotte, Nienke, Rol, Anke, Stooper, Lida, Dijkstra, Helga, Eggenhuizen, Esther, Huijs, Lucas, Moorlag, Simone, Netea, Mihai, Pranger, Eva, Taks, Esther, Oever, Jaap ten, Heine, Rob ter, Blauwendraat, Kitty, Meek, Bob, Erkaya, Isil, Harbech, Houda, Roescher, Nienke, Peeters, Rifka, Riele, Menno te, Zhou, Carmen, Calbo, Esther, Marti, Cristina Badia, Palomares, Emma Triviño, Porcuna, Tomás Perez, Barriocanal, Anabel, Barriocanal, Ana Maria, Casas, Irma, Dominguez, Jose, Esteve, Maria, Lacoma, Alicia, Latorre, Irene, Molina, Gemma, Molina, Barbara, Rosell, Antoni, Vidal, Sandra, Barrera, Lydia, Bustos, Natalia, Calderón, Ines Portillo, Campos, David Gutierrez, Carretero, Jose Manuel, Castellano, Angel Dominguez, Compagnone, Renato, Ramirez de Arellano, Encarnacion, Serna, Almudena de la, Dolores del Toro Lopez, Maria, Clement Espindola, Marie-Alix, Martin Gutierrez, Ana Belen, Hernandez, Alvaro Pascual, Jiménez, Virginia Palomo, Moreno, Elisa, Navarrete, Nicolas, Paño, Teresa Rodriguez, Rodríguez-Baño, Jesús, Tristán, Enriqueta, Rios Villegas, Maria Jose, Garces, Atsegiñe Canga, Amo, Erika Castro, Guerrero, Raquel Coya, Goikoetxea, Josune, Jorge, Leticia, Perez, Cristina, Fariñas Álvarez, María Carmen, Cuadra, Manuel Gutierrez, Arnaiz de las Revillas Almajano, Francisco, Garcia, Pilar Bohedo, Poderos, Teresa Giménez, Rico, Claudia González, Sanchez, Blanca, Valero, Olga, Vega, Noelia, Campbell, John, Barnes, Anna, Catterick, Helen, Cranston, Tim, Dawe, Phoebe, Fletcher, Emily, Fouracre, Liam, Gifford, Alison, Kirkwood, John, Martin, Christopher, McAnew, Amy, Mitchell, Marcus, Newman, Georgina, O'Connell, Abby, Onysk, Jakob, Quinn, Lynne, Rhodes, Shelley, Stone, Samuel, Symons, Lorrie, Tripp, Harry, Warris, Adilia, Watkins, Darcy, Whale, Bethany, Harding, Alex, Lockhart, Gemma, Sidaway-Lee, Kate, Hilton, Sam, Manton, Sarah, Webber-Rookes, Daniel, Winder, Rachel, Moore, James, Bateman, Freya, Gibbons, Michael, Knight, Bridget, Moss, Julie, Statton, Sarah, Studham, Josephine, Hall, Lydia, Moyle, Will, Venton, Tamsin, Pittet, Laure F., Moore, Cecilia L., Dalcolmo, Margareth, Douglas, Mark W., Lacerda, Marcus V.G., Lynn, David J., de Oliveira, Roberto D., Perrett, Kirsten P., Richmond, Peter C., Rocha, Jorge L., Rodriguez-Baño, Jesus, Wood, Nicholas J., and Messina, Nicole L.

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2023
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4. Bacille Calmette-Guérin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial

Author

Pittet, Laure F., primary, Messina, Nicole L., additional, McDonald, Ellie, additional, Orsini, Francesca, additional, Barry, Simone, additional, Bonten, Marc, additional, Campbell, John, additional, Croda, Julio, additional, Croda, Mariana G., additional, Dalcolmo, Margareth, additional, Gardiner, Kaya, additional, Gwee, Amanda, additional, Jardim, Bruno, additional, Lacerda, Marcus V.G., additional, Lucas, Michaela, additional, Lynn, David J., additional, Manning, Laurens, additional, Perrett, Kirsten P., additional, Post, Jeffrey J., additional, Prat-Aymerich, Cristina, additional, Richmond, Peter C., additional, Rocha, Jorge L., additional, Rodriguez-Baño, Jesus, additional, Warris, Adilia, additional, Wood, Nicholas J., additional, Davidson, Andrew, additional, Curtis, Nigel, additional, Jamieson, Tenaya, additional, Messina, Nicole, additional, Morawakage, Thilanka, additional, Perlen, Susan, additional, Perrett, Kirsten, additional, Pittet, Laure, additional, Sastry, Amber, additional, Teo, Jia Wei, additional, Lee, Katherine, additional, Moore, Cecilia, additional, Vidmar, Suzanna, additional, Ali, Rashida, additional, Dunn, Ross, additional, Edler, Peta, additional, Gell, Grace, additional, Goodall, Casey, additional, Hall, Richard, additional, Krastev, Ann, additional, La, Nathan, additional, McPhate, Nick, additional, Nguyen, Thao, additional, Ren, Jack, additional, Stevens, Luke, additional, Alamrousi, Ahmed, additional, Bonnici, Rhian, additional, Dang, Thanh, additional, Germano, Susie, additional, Hua, Jenny, additional, McElroy, Rebecca, additional, Razmovska, Monica, additional, Reddiex, Scott, additional, Wang, Xiaofang, additional, Anderson, Jeremy, additional, Azzopardi, Kristy, additional, Bennett-Wood, Vicki, additional, Czajko, Anna, additional, Mazarakis, Nadia, additional, McCafferty, Conor, additional, Oppedisano, Frances, additional, Ortika, Belinda, additional, Pell, Casey, additional, Spry, Leena, additional, Toh, Ryan, additional, Velagapudi, Sunitha, additional, Vlahos, Amanda, additional, Wee-Hee, Ashleigh, additional, Ramos, Pedro, additional, De La Cruz, Karina, additional, Gamage, Dinusha, additional, Karunanayake, Anushka, additional, Mezzetti, Isabella, additional, Ong, Benjamin, additional, Singh, Ronita, additional, Sooriyarachchi, Enoshini, additional, Nicholson, Suellen, additional, Cain, Natalie, additional, Brizuela, Rianne, additional, Huang, Han, additional, Abruzzo, Veronica, additional, Bealing, Morgan, additional, Bimboese, Patricia, additional, Bowes, Kirsty, additional, Burrell, Emma, additional, Chan, Joyce, additional, Cushnahan, Jac, additional, Elborough, Hannah, additional, Elkington, Olivia, additional, Fahey, Kieran, additional, Fernandez, Monique, additional, Flynn, Catherine, additional, Fowler, Sarah, additional, Andrit, Marie Gentile, additional, Gladanac, Bojana, additional, Hammond, Catherine, additional, Ma, Norine, additional, Macalister, Sam, additional, Milojevic, Emmah, additional, Mojeed, Jesutofunmi, additional, Nguyen, Jill, additional, O'Donnell, Liz, additional, Olivier, Nadia, additional, Ooi, Isabelle, additional, Reynolds, Stephanie, additional, Shen, Lisa, additional, Sherry, Barb, additional, Spotswood, Judith, additional, Wedderburn, Jamie, additional, Younes, Angela, additional, Legge, Donna, additional, Bell, Jason, additional, Cheah, Jo, additional, Cobbledick, Annie, additional, Lim, Kee, additional, Elia, Sonja, additional, Addlem, Lynne, additional, Bourke, Anna, additional, Brophy, Clare, additional, Henare, Nadine, additional, Jenkins, Narelle, additional, Machingaifa, Francesca, additional, Miller, Skye, additional, Mitchell, Kirsten, additional, Pitkin, Sigrid, additional, Wall, Kate, additional, Villanueva, Paola, additional, Crawford, Nigel, additional, Norton, Wendy, additional, Tan, Niki, additional, Chengodu, Thilakavathi, additional, Dawson, Diane, additional, Gordon, Victoria, additional, Korman, Tony, additional, O'Bryan, Jess, additional, Agius, Sophie, additional, Bannister, Samantha, additional, Bucholc, Jess, additional, Burns, Alison, additional, Camesella, Beatriz, additional, Carlin, John, additional, Ciaverella, Marianna, additional, Curtis, Maxwell, additional, Firth, Stephanie, additional, Guo, Christina, additional, Hannan, Matthew, additional, Hill, Erin, additional, Joshi, Sri, additional, Lieschke, Katherine, additional, Mathers, Megan, additional, Odoi, Sasha, additional, Rak, Ashleigh, additional, Richards, Chris, additional, Steve, Leah, additional, Stewart, Carolyn, additional, Sudbury, Eva, additional, Thomson, Helen, additional, Watts, Emma, additional, Williams, Fiona, additional, Young, Angela, additional, Glenn, Penny, additional, Kaynes, Andrew, additional, De Floy, Amandine Philippart, additional, Buchanan, Sandy, additional, Sondag, Thijs, additional, Xie, Ivy, additional, Edmund, Harriet, additional, Byrne, Bridie, additional, Keeble, Tom, additional, Ngien, Belle, additional, Noonan, Fran, additional, Wearing-Smith, Michelle, additional, Clarke, Alison, additional, Davies, Pemma, additional, Eastwood, Oliver, additional, Ellinghaus, Alric, additional, Ghieh, Rachid, additional, Hilton, Zahra, additional, Jennings, Emma, additional, Kakkos, Athina, additional, Liang, Iris, additional, Nicol, Katie, additional, O'Callaghan, Sally, additional, Osman, Helen, additional, Rajaram, Gowri, additional, Ratcliffe, Sophia, additional, Rayner, Victoria, additional, Salmon, Ashleigh, additional, Scheppokat, Angela, additional, Stevens, Aimee, additional, Street, Rebekah, additional, Toogood, Nicholas, additional, Wood, Nicholas, additional, Bahaduri, Twinkle, additional, Baulman, Therese, additional, Byrne, Jennifer, additional, Carter, Candace, additional, Corbett, Mary, additional, Dao, Aiken, additional, Desylva, Maria, additional, Dunn, Andrew, additional, Gardiner, Evangeline, additional, Joyce, Rosemary, additional, Kandasamy, Rama, additional, Munns, Craig, additional, Pelayo, Lisa, additional, Sharma, Ketaki, additional, Sterling, Katrina, additional, Uren, Caitlin, additional, Colaco, Clinton, additional, Douglas, Mark, additional, Hamilton, Kate, additional, Bartlett, Adam, additional, McMullan, Brendan, additional, Palasanthiran, Pamela, additional, Williams, Phoebe, additional, Beardsley, Justin, additional, Bergant, Nikki, additional, Lagunday, Renier, additional, Overton, Kristen, additional, Post, Jeffrey, additional, Al-Hindawi, Yasmeen, additional, Barney, Sarah, additional, Byrne, Anthony, additional, Mead, Lee, additional, Plit, Marshall, additional, Lynn, David, additional, Benson, Saoirse, additional, Blake, Stephen, additional, Botten, Rochelle, additional, Chern, Tee Yee, additional, Eden, Georgina, additional, Griffith, Liddy, additional, James, Jane, additional, Lynn, Miriam, additional, Markow, Angela, additional, Sacca, Domenic, additional, Stevens, Natalie, additional, Wesselingh, Steve, additional, Doran, Catriona, additional, Sawka, Alice, additional, Evans, Sue, additional, Goodchild, Louise, additional, Heath, Christine, additional, Krieg, Meredith, additional, Marshall, Helen, additional, McMillan, Mark, additional, Walker, Mary, additional, Richmond, Peter, additional, Amenyogbe, Nelly, additional, Anthony, Christina, additional, Arnold, Annabelle, additional, Arrowsmith, Beth, additional, Ben-Othman, Rym, additional, Clark, Sharon, additional, Dunnill, Jemma, additional, Eiffler, Nat, additional, Ewe, Krist, additional, Finucane, Carolyn, additional, Flynn, Lorraine, additional, Gibson, Camille, additional, Hartnell, Lucy, additional, Hollams, Elysia, additional, Hutton, Heidi, additional, Jarvis, Lance, additional, Jones, Jane, additional, Jones, Jan, additional, Jones, Karen, additional, Kent, Jennifer, additional, Kollmann, Tobias, additional, Lalich, Debbie, additional, Lee, Wenna, additional, Lim, Rachel, additional, McAlister, Sonia, additional, McDonald, Fiona, additional, Meehan, Andrea, additional, Minhaj, Asma, additional, Montgomery, Lisa, additional, O'Donnell, Melissa, additional, Ong, Jaslyn, additional, Ong, Joanne, additional, Parkin, Kimberley, additional, Perez, Glady, additional, Power, Catherine, additional, Rezazadeh, Shadie, additional, Richmond, Holly, additional, Rogers, Sally, additional, Schultz, Nikki, additional, Shave, Margaret, additional, Skut, Patrycja, additional, Stiglmayer, Lisa, additional, Truelove, Alexandra, additional, Wadia, Ushma, additional, Wallace, Rachael, additional, Waring, Justin, additional, England, Michelle, additional, Latkovic, Erin, additional, Herrmann, Susan, additional, Lacerda, Marcus, additional, Andrade, Paulo Henrique, additional, Barbosa, Fabiane Bianca, additional, Barros, Dayanne, additional, Brasil, Larissa, additional, Capella, Ana Greyce, additional, Castro, Ramon, additional, Costa, Erlane, additional, de Souza, Dilcimar, additional, Dias, Maianne, additional, Dias, José, additional, Ferreira, Klenilson, additional, Figueiredo, Paula, additional, Freitas, Thamires, additional, Furtado, Ana Carolina, additional, Gama, Larissa, additional, Godinho, Vanessa, additional, Gouy, Cintia, additional, Hinojosa, Daniele, additional, Jardim, Tyane, additional, Junior, Joel, additional, Lima, Augustto, additional, Maia, Bernardo, additional, Marins, Adriana, additional, Mazurega, Kelry, additional, Medeiros, Tercilene, additional, Melo, Rosangela, additional, Moraes, Marinete, additional, Nascimento, Elizandra, additional, Neves, Juliana, additional, Oliveira, Maria Gabriela, additional, Oliveira, Thais, additional, Oliveira, Ingrid, additional, Otsuka, Arthur, additional, Paes, Rayssa, additional, Pereira, Handerson, additional, Pereira, Gabrielle, additional, Prado, Christiane, additional, Queiroz, Evelyn, additional, Rodrigues, Laleyska, additional, Rodrigues, Bebeto, additional, Sampaio, Vanderson, additional, Santos, Anna Gabriela, additional, Santos, Daniel, additional, Santos, Tilza, additional, Santos, Evelyn, additional, Sartim, Ariandra, additional, Silva, Ana Beatriz, additional, Silva, Juliana, additional, Silva, Emanuelle, additional, Simão, Mariana, additional, Soares, Caroline, additional, Sousa, Antonny, additional, Trindade, Alexandre, additional, Val, Fernando, additional, Vasconcelos, Adria, additional, Vasconcelos, Heline, additional, Abreu, Carolinne, additional, Almeida, Katya Martinez, additional, Bitencourt de Andrade, Camila, additional, Campos Angelo, Jhenyfer Thalyta, additional, Gonçalvez de Araújo Arcanjo, Ghislaine, additional, Silva Menezes Arruda, Bianca Maria, additional, Ayala, Wellyngthon Espindola, additional, Refosco Barbosa, Adelita Agripina, additional, Vieira Batista, Felipe Zampieri, additional, de Morais Batista, Fabiani, additional, de Jesus Costa, Miriam, additional, Croda, Mariana Garcia, additional, Alves da Cruz, Lais, additional, Pereira Diogo, Roberta Carolina, additional, Dutra Escobar, Rodrigo Cezar, additional, Fernandes, Iara Rodrigues, additional, Figueiredo, Leticia Ramires, additional, Cavalcanti Gonçalves, Leandro Galdino, additional, Lahdo, Sarita, additional, Lencina, Joyce dos Santos, additional, Teodoro de Lima, Guilherme, additional, LEOPOLDINA MEIRELES, Bruna Tayara, additional, Moreira, Debora Quadros, additional, Silva Muranaka, Lilian Batista, additional, de Oliveira, Adriely, additional, Warszawski de Oliveira, Karla Regina, additional, Vieira de Oliveira, Matheus, additional, Dias de Oliveira, Roberto, additional, Pereira, Andrea Antonia Souza de Almeida dos Reis, additional, Puga, Marco, additional, Ramos, Caroliny Veron, additional, Souza da Rosa, Thaynara Haynara, additional, Lopes dos Santos, Karla, additional, Ribeiro dos Santos, Claudinalva, additional, Leopoldina dos Santos, Dyenyffer Stéffany, additional, Santos, Karina Marques, additional, Pereira da Silva, Paulo César, additional, Rocha da Silva, Paulo Victor, additional, Silva, Débora dos Santos, additional, Vieira da Silva, Patricia, additional, Freitas da Rosa Soares, Bruno, additional, Sperotto, Mariana Gazzoni, additional, Tadokoro, Mariana Mayumi, additional, Tsuha, Daniel, additional, Ramos Vieira, Hugo Miguel, additional, Pretti Dalcolmo, Margareth Maria, additional, Lopes Alves da Paixão, Cíntia Maria, additional, Corrêa E Castro, Gabriela, additional, Collopy, Simone Silva, additional, da Costa Silva, Renato, additional, Almeida da Silveira, Samyra, additional, Da-Cruz, Alda Maria, additional, Maria da Silva Passos de Carvalho, Alessandra, additional, de Cássia Batista, Rita, additional, Silva De Freitas, Maria Luciana, additional, Gerhardt de Oliveira Ferreira, Aline, additional, Conceição de Souza, Ana Paula, additional, Doblas, Paola Cerbino, additional, Alcoforado da Silva dos Santos, Ayla, additional, Cristine de Moraes dos Santos, Vanessa, additional, Alves dos Santos Gomes, Dayane, additional, Fortunato, Anderson Lage, additional, Gomes-Silva, Adriano, additional, Gonçalves, Monique Pinto, additional, Garcia Meireless Junior, Paulo Leandro, additional, Martins da Costa Carvalho, Estela, additional, Motta, Fernando do Couto, additional, Olivo de Mendonça, Ligia Maria, additional, Pandine, Girlene dos Santos, additional, Plácido Pereira, Rosa Maria, additional, Maia, Ivan Ramos, additional, Luiz da Rocha, Jorge, additional, Paiva Romano, João Victor, additional, Santos, Glauce dos, additional, Fernandes da Silva, Erica, additional, Mendonça Teixeira de Siqueira, Marilda Agudo, additional, Prudêncio Soares, Ágatha Cristinne, additional, Arroyo, Sandra Franch, additional, Besten, Henny Ophorst-den, additional, Boon, Anna, additional, Brakke, Karin M., additional, Janssen, Axel, additional, Koopmans, Marijke A.H., additional, Lemmens, Toos, additional, Leurink, Titia, additional, Septer-Bijleveld, Engelien, additional, Stadhouders, Kimberly, additional, Troeman, Darren, additional, van der Waal, Marije, additional, van Opdorp, Marjoleine, additional, van Sluis, Nicolette, additional, Wolters, Beatrijs, additional, Kluytmans, Jan, additional, Romme, Jannie, additional, van den Bijllaardt, Wouter, additional, van Mook, Linda, additional, Rijen, M.M.L (Miranda) van, additional, Filius, P.M.G., additional, Gisolf, Jet, additional, Greven, Frances, additional, Huijbens, Danique, additional, Hassing, Robert Jan, additional, Pon, R.C., additional, Preijers, Lieke, additional, van Leusen, J.H., additional, Verheij, Harald, additional, Boersma, Wim, additional, Brans, Evelien, additional, Kloeg, Paul, additional, Molenaar-Groot, Kitty, additional, Nguyen, Nhat Khanh, additional, Paternotte, Nienke, additional, Rol, Anke, additional, Stooper, Lida, additional, Dijkstra, Helga, additional, Eggenhuizen, Esther, additional, Huijs, Lucas, additional, Moorlag, Simone, additional, Netea, Mihai, additional, Pranger, Eva, additional, Taks, Esther, additional, Oever, Jaap ten, additional, Heine, Rob ter, additional, Blauwendraat, Kitty, additional, Meek, Bob, additional, Erkaya, Isil, additional, Harbech, Houda, additional, Roescher, Nienke, additional, Peeters, Rifka, additional, Riele, Menno te, additional, Zhou, Carmen, additional, Calbo, Esther, additional, Marti, Cristina Badia, additional, Palomares, Emma Triviño, additional, Porcuna, Tomás Perez, additional, Barriocanal, Anabel, additional, Barriocanal, Ana Maria, additional, Casas, Irma, additional, Dominguez, Jose, additional, Esteve, Maria, additional, Lacoma, Alicia, additional, Latorre, Irene, additional, Molina, Gemma, additional, Molina, Barbara, additional, Rosell, Antoni, additional, Vidal, Sandra, additional, Barrera, Lydia, additional, Bustos, Natalia, additional, Calderón, Ines Portillo, additional, Campos, David Gutierrez, additional, Carretero, Jose Manuel, additional, Castellano, Angel Dominguez, additional, Compagnone, Renato, additional, Ramirez de Arellano, Encarnacion, additional, Serna, Almudena de la, additional, del Toro Lopez, Maria Dolores, additional, Clement Espindola, Marie-Alix, additional, Martin Gutierrez, Ana Belen, additional, Hernandez, Alvaro Pascual, additional, Jiménez, Virginia Palomo, additional, Moreno, Elisa, additional, Navarrete, Nicolas, additional, Paño, Teresa Rodriguez, additional, Rodríguez-Baño, Jesús, additional, Tristán, Enriqueta, additional, Rios Villegas, Maria Jose, additional, Garces, Atsegiñe Canga, additional, Amo, Erika Castro, additional, Guerrero, Raquel Coya, additional, Goikoetxea, Josune, additional, Jorge, Leticia, additional, Perez, Cristina, additional, Fariñas Álvarez, María Carmen, additional, Cuadra, Manuel Gutierrez, additional, Arnaiz de las Revillas Almajano, Francisco, additional, Garcia, Pilar Bohedo, additional, Poderos, Teresa Giménez, additional, Rico, Claudia González, additional, Sanchez, Blanca, additional, Valero, Olga, additional, Vega, Noelia, additional, Barnes, Anna, additional, Catterick, Helen, additional, Cranston, Tim, additional, Dawe, Phoebe, additional, Fletcher, Emily, additional, Fouracre, Liam, additional, Gifford, Alison, additional, Gow, Neil, additional, Kirkwood, John, additional, Martin, Christopher, additional, McAnew, Amy, additional, Mitchell, Marcus, additional, Newman, Georgina, additional, O'Connell, Abby, additional, Onysk, Jakob, additional, Quinn, Lynne, additional, Rhodes, Shelley, additional, Stone, Samuel, additional, Symons, Lorrie, additional, Tripp, Harry, additional, Watkins, Darcy, additional, Whale, Bethany, additional, Harding, Alex, additional, Lockhart, Gemma, additional, Sidaway-Lee, Kate, additional, Hilton, Sam, additional, Manton, Sarah, additional, Webber-Rookes, Daniel, additional, Winder, Rachel, additional, Moore, James, additional, Bateman, Freya, additional, Gibbons, Michael, additional, Knight, Bridget, additional, Moss, Julie, additional, Statton, Sarah, additional, Studham, Josephine, additional, Hall, Lydia, additional, Moyle, Will, additional, and Venton, Tamsin, additional

Published
2024
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6. Bacillus Calmette-Guérin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial

Author

Pittet, Laure F., primary, Moore, Cecilia L., additional, McDonald, Ellie, additional, Barry, Simone, additional, Bonten, Marc, additional, Campbell, John, additional, Croda, Julio, additional, Dalcolmo, Margareth, additional, Davidson, Andrew, additional, Douglas, Mark W., additional, Gardiner, Kaya, additional, Gwee, Amanda, additional, Jardim, Bruno, additional, Lacerda, Marcus V.G., additional, Lucas, Michaela, additional, Lynn, David J., additional, Manning, Laurens, additional, de Oliveira, Roberto D., additional, Perrett, Kirsten P., additional, Prat-Aymerich, Cristina, additional, Richmond, Peter C., additional, Rocha, Jorge L., additional, Rodriguez-Baño, Jesus, additional, Warris, Adilia, additional, Wood, Nicholas J., additional, Messina, Nicole L., additional, Curtis, Nigel, additional, Jamieson, Tenaya, additional, Messina, Nicole, additional, Morawakage, Thilanka, additional, Perlen, Susan, additional, Perrett, Kirsten, additional, Pittet, Laure, additional, Sastry, Amber, additional, Teo, Jia Wei, additional, Orsini, Francesca, additional, Lee, Katherine, additional, Moore, Cecilia, additional, Vidmar, Suzanna, additional, Ali, Rashida, additional, Dunn, Ross, additional, Edler, Peta, additional, Gell, Grace, additional, Goodall, Casey, additional, Hall, Richard, additional, Krastev, Ann, additional, La, Nathan, additional, McPhate, Nick, additional, Nguyen, Thao, additional, Ren, Jack, additional, Stevens, Luke, additional, Alamrousi, Ahmed, additional, Bonnici, Rhian, additional, Dang, Thanh, additional, Germano, Susie, additional, Hua, Jenny, additional, McElroy, Rebecca, additional, Razmovska, Monica, additional, Reddiex, Scott, additional, Wang, Xiaofang, additional, Anderson, Jeremy, additional, Azzopardi, Kristy, additional, Bennett-Wood, Vicki, additional, Czajko, Anna, additional, Mazarakis, Nadia, additional, McCafferty, Conor, additional, Oppedisano, Frances, additional, Ortika, Belinda, additional, Pell, Casey, additional, Spry, Leena, additional, Toh, Ryan, additional, Velagapudi, Sunitha, additional, Vlahos, Amanda, additional, Wee-Hee, Ashleigh, additional, Ramos, Pedro, additional, De La Cruz, Karina, additional, Gamage, Dinusha, additional, Karunanayake, Anushka, additional, Mezzetti, Isabella, additional, Ong, Benjamin, additional, Singh, Ronita, additional, Sooriyarachchi, Enoshini, additional, Nicholson, Suellen, additional, Cain, Natalie, additional, Brizuela, Rianne, additional, Huang, Han, additional, Abruzzo, Veronica, additional, Bealing, Morgan, additional, Bimboese, Patricia, additional, Bowes, Kirsty, additional, Burrell, Emma, additional, Chan, Joyce, additional, Cushnahan, Jac, additional, Elborough, Hannah, additional, Elkington, Olivia, additional, Fahey, Kieran, additional, Fernandez, Monique, additional, Flynn, Catherine, additional, Fowler, Sarah, additional, Andrit, Marie Gentile, additional, Gladanac, Bojana, additional, Hammond, Catherine, additional, Ma, Norine, additional, Macalister, Sam, additional, Milojevic, Emmah, additional, Mojeed, Jesutofunmi, additional, Nguyen, Jill, additional, O'Donnell, Liz, additional, Olivier, Nadia, additional, Ooi, Isabelle, additional, Reynolds, Stephanie, additional, Shen, Lisa, additional, Sherry, Barb, additional, Spotswood, Judith, additional, Wedderburn, Jamie, additional, Younes, Angela, additional, Legge, Donna, additional, Bell, Jason, additional, Cheah, Jo, additional, Cobbledick, Annie, additional, Lim, Kee, additional, Elia, Sonja, additional, Addlem, Lynne, additional, Bourke, Anna, additional, Brophy, Clare, additional, Henare, Nadine, additional, Jenkins, Narelle, additional, Machingaifa, Francesca, additional, Miller, Skye, additional, Mitchell, Kirsten, additional, Pitkin, Sigrid, additional, Wall, Kate, additional, Villanueva, Paola, additional, Crawford, Nigel, additional, Norton, Wendy, additional, Tan, Niki, additional, Chengodu, Thilakavathi, additional, Dawson, Diane, additional, Gordon, Victoria, additional, Korman, Tony, additional, O'Bryan, Jess, additional, Agius, Sophie, additional, Bannister, Samantha, additional, Bucholc, Jess, additional, Burns, Alison, additional, Camesella, Beatriz, additional, Carlin, John, additional, Ciaverella, Marianna, additional, Curtis, Maxwell, additional, Firth, Stephanie, additional, Guo, Christina, additional, Hannan, Matthew, additional, Hill, Erin, additional, Joshi, Sri, additional, Lieschke, Katherine, additional, Mathers, Megan, additional, Odoi, Sasha, additional, Rak, Ashleigh, additional, Richards, Chris, additional, Steve, Leah, additional, Stewart, Carolyn, additional, Sudbury, Eva, additional, Thomson, Helen, additional, Watts, Emma, additional, Williams, Fiona, additional, Young, Angela, additional, Glenn, Penny, additional, Kaynes, Andrew, additional, Philippart De Floy, Amandine, additional, Buchanan, Sandy, additional, Sondag, Thijs, additional, Xie, Ivy, additional, Edmund, Harriet, additional, Byrne, Bridie, additional, Keeble, Tom, additional, Ngien, Belle, additional, Noonan, Fran, additional, Wearing-Smith, Michelle, additional, Clarke, Alison, additional, Davies, Pemma, additional, Eastwood, Oliver, additional, Ellinghaus, Alric, additional, Ghieh, Rachid, additional, Hilton, Zahra, additional, Jennings, Emma, additional, Kakkos, Athina, additional, Liang, Iris, additional, Nicol, Katie, additional, O'Callaghan, Sally, additional, Osman, Helen, additional, Rajaram, Gowri, additional, Ratcliffe, Sophia, additional, Rayner, Victoria, additional, Salmon, Ashleigh, additional, Scheppokat, Angela, additional, Stevens, Aimee, additional, Street, Rebekah, additional, Toogood, Nicholas, additional, Wood, Nicholas, additional, Bahaduri, Twinkle, additional, Baulman, Therese, additional, Byrne, Jennifer, additional, Carter, Candace, additional, Corbett, Mary, additional, Dao, Aiken, additional, Desylva, Maria, additional, Dunn, Andrew, additional, Gardiner, Evangeline, additional, Joyce, Rosemary, additional, Kandasamy, Rama, additional, Munns, Craig, additional, Pelayo, Lisa, additional, Sharma, Ketaki, additional, Sterling, Katrina, additional, Uren, Caitlin, additional, Colaco, Clinton, additional, Douglas, Mark, additional, Hamilton, Kate, additional, Bartlett, Adam, additional, McMullan, Brendan, additional, Palasanthiran, Pamela, additional, Williams, Phoebe, additional, Beardsley, Justin, additional, Bergant, Nikki, additional, Lagunday, Renier, additional, Overton, Kristen, additional, Post, Jeffrey, additional, Al-Hindawi, Yasmeen, additional, Barney, Sarah, additional, Byrne, Anthony, additional, Mead, Lee, additional, Plit, Marshall, additional, Lynn, David, additional, Benson, Saoirse, additional, Blake, Stephen, additional, Botten, Rochelle, additional, Chern, Tee Yee, additional, Eden, Georgina, additional, Griffith, Liddy, additional, James, Jane, additional, Lynn, Miriam, additional, Markow, Angela, additional, Sacca, Domenic, additional, Stevens, Natalie, additional, Wesselingh, Steve, additional, Doran, Catriona, additional, Sawka, Alice, additional, Evans, Sue, additional, Goodchild, Louise, additional, Heath, Christine, additional, Krieg, Meredith, additional, Marshall, Helen, additional, McMillan, Mark, additional, Walker, Mary, additional, Richmond, Peter, additional, Amenyogbe, Nelly, additional, Anthony, Christina, additional, Arnold, Annabelle, additional, Arrowsmith, Beth, additional, Ben-Othman, Rym, additional, Clark, Sharon, additional, Dunnill, Jemma, additional, Eiffler, Nat, additional, Ewe, Krist, additional, Finucane, Carolyn, additional, Flynn, Lorraine, additional, Gibson, Camille, additional, Hartnell, Lucy, additional, Hollams, Elysia, additional, Hutton, Heidi, additional, Jarvis, Lance, additional, Jones, Jane, additional, Jones, Jan, additional, Jones, Karen, additional, Kent, Jennifer, additional, Kollmann, Tobias, additional, Lalich, Debbie, additional, Lee, Wenna, additional, Lim, Rachel, additional, McAlister, Sonia, additional, McDonald, Fiona, additional, Meehan, Andrea, additional, Minhaj, Asma, additional, Montgomery, Lisa, additional, O'Donnell, Melissa, additional, Ong, Jaslyn, additional, Ong, Joanne, additional, Parkin, Kimberley, additional, Perez, Glady, additional, Power, Catherine, additional, Rezazadeh, Shadie, additional, Richmond, Holly, additional, Rogers, Sally, additional, Schultz, Nikki, additional, Shave, Margaret, additional, Skut, Patrycja, additional, Stiglmayer, Lisa, additional, Truelove, Alexandra, additional, Wadia, Ushma, additional, Wallace, Rachael, additional, Waring, Justin, additional, England, Michelle, additional, Latkovic, Erin, additional, Herrmann, Susan, additional, Lacerda, Marcus, additional, Andrade, Paulo Henrique, additional, Barbosa, Fabiane Bianca, additional, Barros, Dayanne, additional, Brasil, Larissa, additional, Capella, Ana Greyce, additional, Castro, Ramon, additional, Costa, Erlane, additional, de Souza, Dilcimar, additional, Dias, Maianne, additional, Dias, José, additional, Ferreira, Klenilson, additional, Figueiredo, Paula, additional, Freitas, Thamires, additional, Furtado, Ana Carolina, additional, Gama, Larissa, additional, Godinho, Vanessa, additional, Gouy, Cintia, additional, Hinojosa, Daniele, additional, Jardim, Tyane, additional, Junior, Joel, additional, Lima, Augustto, additional, Maia, Bernardo, additional, Marins, Adriana, additional, Mazurega, Kelry, additional, Medeiros, Tercilene, additional, Melo, Rosangela, additional, Moraes, Marinete, additional, Nascimento, Elizandra, additional, Neves, Juliana, additional, Oliveira, Maria Gabriela, additional, Oliveira, Thais, additional, Oliveira, Ingrid, additional, Otsuka, Arthur, additional, Paes, Rayssa, additional, Pereira, Handerson, additional, Pereira, Gabrielle, additional, Prado, Christiane, additional, Queiroz, Evelyn, additional, Rodrigues, Laleyska, additional, Rodrigues, Bebeto, additional, Sampaio, Vanderson, additional, Santos, Anna Gabriela, additional, Santos, Daniel, additional, Santos, Tilza, additional, Santos, Evelyn, additional, Sartim, Ariandra, additional, Silva, Ana Beatriz, additional, Silva, Juliana, additional, Silva, Emanuelle, additional, Simão, Mariana, additional, Soares, Caroline, additional, Sousa, Antonny, additional, Trindade, Alexandre, additional, Val, Fernando, additional, Vasconcelos, Adria, additional, Vasconcelos, Heline, additional, Abreu, Carolinne, additional, Almeida, Katya Martinez, additional, Bitencourt de Andrade, Camila, additional, Campos Angelo, Jhenyfer Thalyta, additional, Gonçalvez de Araújo Arcanjo, Ghislaine, additional, Silva Menezes Arruda, Bianca Maria, additional, Ayala, Wellyngthon Espindola, additional, Refosco Barbosa, Adelita Agripina, additional, Vieira Batista, Felipe Zampieri, additional, de Morais Batista, Fabiani, additional, de Jesus Costa, Miriam, additional, Croda, Mariana Garcia, additional, Alves da Cruz, Lais, additional, Pereira Diogo, Roberta Carolina, additional, Dutra Escobar, Rodrigo Cezar, additional, Fernandes, Iara Rodrigues, additional, Figueiredo, Leticia Ramires, additional, Cavalcanti Gonçalves, Leandro Galdino, additional, Lahdo, Sarita, additional, Lencina, Joyce dos Santos, additional, Teodoro de Lima, Guilherme, additional, Matos, Larissa Santos, additional, Leopoldina Meireles, Bruna Tayara, additional, Moreira, Debora Quadros, additional, Silva Muranaka, Lilian Batista, additional, de Oliveira, Adriely, additional, Warszawski de Oliveira, Karla Regina, additional, Vieira de Oliveira, Matheus, additional, Dias de Oliveira, Roberto, additional, Souza de Almeida dos Reis Pereira, Andrea Antonia, additional, Puga, Marco, additional, Ramos, Caroliny Veron, additional, Souza da Rosa, Thaynara Haynara, additional, Lopes dos Santos, Karla, additional, Ribeiro dos Santos, Claudinalva, additional, Leopoldina dos Santos, Dyenyffer Stéffany, additional, Santos, Karina Marques, additional, Pereira da Silva, Paulo César, additional, Rocha da Silva, Paulo Victor, additional, Silva, Débora dos Santos, additional, Vieira da Silva, Patricia, additional, Freitas da Rosa Soares, Bruno, additional, Sperotto, Mariana Gazzoni, additional, Tadokoro, Mariana Mayumi, additional, Tsuha, Daniel, additional, Ramos Vieira, Hugo Miguel, additional, Pretti Dalcolmo, Margareth Maria, additional, Lopes Alves da Paixão, Cíntia Maria, additional, Corrêa E Castro, Gabriela, additional, Collopy, Simone Silva, additional, da Costa Silva, Renato, additional, Almeida da Silveira, Samyra, additional, Da-Cruz, Alda Maria, additional, Maria da Silva Passos de Carvalho, Alessandra, additional, de Cássia Batista, Rita, additional, Silva De Freitas, Maria Luciana, additional, Gerhardt de Oliveira Ferreira, Aline, additional, Conceição de Souza, Ana Paula, additional, Doblas, Paola Cerbino, additional, Alcoforado da Silva dos Santos, Ayla, additional, Cristine de Moraes dos Santos, Vanessa, additional, Alves dos Santos Gomes, Dayane, additional, Fortunato, Anderson Lage, additional, Gomes-Silva, Adriano, additional, Gonçalves, Monique Pinto, additional, Garcia Meireless Junior, Paulo Leandro, additional, Martins da Costa Carvalho, Estela, additional, Motta, Fernando do Couto, additional, Olivo de Mendonça, Ligia Maria, additional, Pandine, Girlene dos Santos, additional, Plácido Pereira, Rosa Maria, additional, Maia, Ivan Ramos, additional, Luiz da Rocha, Jorge, additional, Paiva Romano, João Victor, additional, Santos, Glauce dos, additional, Fernandes da Silva, Erica, additional, Mendonça Teixeira de Siqueira, Marilda Agudo, additional, Prudêncio Soares, Ágatha Cristinne, additional, Arroyo, Sandra Franch, additional, Besten, Henny Ophorst-den, additional, Boon, Anna, additional, Brakke, Karin M., additional, Janssen, Axel, additional, Koopmans, Marijke A.H., additional, Lemmens, Toos, additional, Leurink, Titia, additional, Septer-Bijleveld, Engelien, additional, Stadhouders, Kimberly, additional, Troeman, Darren, additional, van der Waal, Marije, additional, van Opdorp, Marjoleine, additional, van Sluis, Nicolette, additional, Wolters, Beatrijs, additional, Kluytmans, Jan, additional, Romme, Jannie, additional, van den Bijllaardt, Wouter, additional, van Mook, Linda, additional, Rijen, M.M.L (Miranda) van, additional, Filius, P.M.G., additional, Gisolf, Jet, additional, Greven, Frances, additional, Huijbens, Danique, additional, Hassing, Robert Jan, additional, Pon, R.C., additional, Preijers, Lieke, additional, van Leusen, J.H., additional, Verheij, Harald, additional, Boersma, Wim, additional, Brans, Evelien, additional, Kloeg, Paul, additional, Molenaar-Groot, Kitty, additional, Nguyen, Nhat Khanh, additional, Paternotte, Nienke, additional, Rol, Anke, additional, Stooper, Lida, additional, Dijkstra, Helga, additional, Eggenhuizen, Esther, additional, Huijs, Lucas, additional, Moorlag, Simone, additional, Netea, Mihai, additional, Pranger, Eva, additional, Taks, Esther, additional, Oever, Jaap ten, additional, Heine, Rob ter, additional, Blauwendraat, Kitty, additional, Meek, Bob, additional, Erkaya, Isil, additional, Harbech, Houda, additional, Roescher, Nienke, additional, Peeters, Rifka, additional, Riele, Menno te, additional, Zhou, Carmen, additional, Calbo, Esther, additional, Marti, Cristina Badia, additional, Palomares, Emma Triviño, additional, Porcuna, Tomás Perez, additional, Barriocanal, Anabel, additional, Barriocanal, Ana Maria, additional, Casas, Irma, additional, Dominguez, Jose, additional, Esteve, Maria, additional, Lacoma, Alicia, additional, Latorre, Irene, additional, Molina, Gemma, additional, Molina, Barbara, additional, Rosell, Antoni, additional, Vidal, Sandra, additional, Barrera, Lydia, additional, Bustos, Natalia, additional, Calderón, Ines Portillo, additional, Campos, David Gutierrez, additional, Carretero, Jose Manuel, additional, Castellano, Angel Dominguez, additional, Compagnone, Renato, additional, Ramirez de Arellano, Encarnacion, additional, Serna, Almudena de la, additional, Dolores del Toro Lopez, Maria, additional, Clement Espindola, Marie-Alix, additional, Martin Gutierrez, Ana Belen, additional, Hernandez, Alvaro Pascual, additional, Jiménez, Virginia Palomo, additional, Moreno, Elisa, additional, Navarrete, Nicolas, additional, Paño, Teresa Rodriguez, additional, Rodríguez-Baño, Jesús, additional, Tristán, Enriqueta, additional, Rios Villegas, Maria Jose, additional, Garces, Atsegiñe Canga, additional, Amo, Erika Castro, additional, Guerrero, Raquel Coya, additional, Goikoetxea, Josune, additional, Jorge, Leticia, additional, Perez, Cristina, additional, Fariñas Álvarez, María Carmen, additional, Cuadra, Manuel Gutierrez, additional, Arnaiz de las Revillas Almajano, Francisco, additional, Garcia, Pilar Bohedo, additional, Poderos, Teresa Giménez, additional, Rico, Claudia González, additional, Sanchez, Blanca, additional, Valero, Olga, additional, Vega, Noelia, additional, Barnes, Anna, additional, Catterick, Helen, additional, Cranston, Tim, additional, Dawe, Phoebe, additional, Fletcher, Emily, additional, Fouracre, Liam, additional, Gifford, Alison, additional, Kirkwood, John, additional, Martin, Christopher, additional, McAnew, Amy, additional, Mitchell, Marcus, additional, Newman, Georgina, additional, O'Connell, Abby, additional, Onysk, Jakob, additional, Quinn, Lynne, additional, Rhodes, Shelley, additional, Stone, Samuel, additional, Symons, Lorrie, additional, Tripp, Harry, additional, Watkins, Darcy, additional, Whale, Bethany, additional, Harding, Alex, additional, Lockhart, Gemma, additional, Sidaway-Lee, Kate, additional, Hilton, Sam, additional, Manton, Sarah, additional, Webber-Rookes, Daniel, additional, Winder, Rachel, additional, Moore, James, additional, Bateman, Freya, additional, Gibbons, Michael, additional, Knight, Bridget, additional, Moss, Julie, additional, Statton, Sarah, additional, Studham, Josephine, additional, Hall, Lydia, additional, Moyle, Will, additional, and Venton, Tamsin, additional

Published
2023
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10. A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study

Author

Osowicki, Joshua, primary, Azzopardi, Kristy I, additional, Fabri, Loraine, additional, Frost, Hannah R, additional, Rivera-Hernandez, Tania, additional, Neeland, Melanie R, additional, Whitcombe, Alana L, additional, Grobler, Anneke, additional, Gutman, Sarah J, additional, Baker, Ciara, additional, Wong, Janet M F, additional, Lickliter, Jason D, additional, Waddington, Claire S, additional, Pandey, Manisha, additional, Schuster, Tibor, additional, Cheng, Allen C, additional, Pollard, Andrew J, additional, McCarthy, James S, additional, Good, Michael F, additional, Dale, James B, additional, Batzloff, Michael, additional, Moreland, Nicole J, additional, Walker, Mark J, additional, Carapetis, Jonathan R, additional, Smeesters, Pierre R, additional, and Steer, Andrew C, additional

Published
2021
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11. Additional file 4 of An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Author

Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., and Steer, Andrew C.

Abstract

Additional file 4: Table S1. Specificity of the emm75 qPCR. S. pyogenes from different emm-clusters and other respiratory pathogens were used to demonstrate the specificity of the emm75 qPCR. Each value is the mean of duplicate reactions. Samples with no provided Ct value failed to cross the fluorescence threshold by the 40th (last) cycle of the assay and all samples with Ct values greater than 35 were considered negative. No template control was included and this did not cross the fluorescence threshold by the 40th cycle.

Published
2021
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12. Additional file 6 of An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Author

Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., and Steer, Andrew C.

Abstract

Additional file 6: Table S3. gyrA RT-qPCR and NanoDrop RNA readings. Comparison between RNA-only and single column combined extraction methods (RNA eluted first). Refer to Fig. 2b RNA readings.

Published
2021
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13. Additional file 7 of An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Author

Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., and Steer, Andrew C.

Abstract

Additional file 7: Table S4. Detailed timeline of discrepancies between culture and qPCR results. Twenty swabs were positive by emm75 qPCR and negative by culture. These swabs were either collected within 48 h after inoculation (N = 4) or within 36 h after initiation of antibiotic treatment (N = 16). 0, pre challenge; + 24, 24 h post challenge; Abx, antibiotics; + 1 w, 1 week post discharge; + 1 m, 1 month post discharge; + 3 m, 3 months post discharge.

Published
2021
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15. Additional file 5 of An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Author

Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., and Steer, Andrew C.

Abstract

Additional file 5: Table S2. Emm75 qPCR and NanoDrop DNA readings. Comparison between DNA-only and single column combined extraction methods (RNA eluted first). Refer to Fig. 2b DNA readings.

Published
2021
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16. Additional file 3 of An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

Author

Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., and Steer, Andrew C.

Abstract

Additional file 3: Figure S2. Standard curve for determination of emm75 GE in eNats™ by qPCR. Seven-point standard curves were included on each emm75 qPCR plate and used to extrapolate bacterial load for eNat™ throat swabs from the CHIVAS-M75 trial, expressed as emm75 genome equivalents (GE) per ml of eNat™ medium. The dotted line represents the limit of detection Ct ≤ 35. Mean and standard deviation shown from 7 duplicate runs.

Published
2021
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18. Transcriptional analysis of the grlRA virulence operon from Citrobacter rodentium

Author

Tauschek, Marija, Yang, Ji, Hocking, Dianna, Azzopardi, Kristy, Tan, Aimee, Hart, Emily, Praszkier, Judyta, and Robins-Browne, Roy M.

Subjects
Promoters (Genetics) -- Physiological aspects, Virulence (Microbiology) -- Genetic aspects, Operons -- Physiological aspects, Enterobacter -- Genetic aspects, Enterobacter -- Physiological aspects, Enterobacteriaceae -- Genetic aspects, Enterobacteriaceae -- Physiological aspects, Biological sciences
Abstract

The locus for enterocyte effacement (LEE) is the virulence hallmark of the attaching-and-effacing (A/E) intestinal pathogens, namely, enteropathogenic Escherichia coli, enterohemorrhagic E. coli, and Citrobacter rodentium. The LEE carries more than 40 genes that are arranged in several operons, e.g., LEE1 to LEE5. Expression of the various transcriptional units is subject to xenogeneic silencing by the histone-like protein H-NS. The LEE1-encoded regulator, Ler, plays a key role in relieving this repression at several major LEE promoters, including LEE2 to LEE5. To achieve appropriate intracellular concentrations of Ler in different environments, A/E pathogens have evolved a sophisticated regulatory network to control ler expression. For example, the LEE-encoded GrlA and GrlR proteins work as activator and antiactivator, respectively, of ler transcription. Thus, control of the transcriptional activities of the LEE1 (ler) promoter and the grlRA operon determines the rate of transcription of all of the LEE-encoded virulence factors. To date, only a single promoter has been identified for the grlRA operon. In this study, we showed that the non-LEE-encoded AraC-like regulatory protein RegA of C. rodentium directly stimulates transcription of the grlRA promoter by binding to an upstream region in the presence of bicarbonate ions. In addition, in vivo and in vitro transcription assays revealed a [[sigma].sup.70] promoter that is specifically responsible for transcription of grlA. Expression from this promoter was strongly repressed by H-NS and its paralog StpA but was activated by Ler. DNase I footprinting demonstrated that Let binds to a region upstream of the grlA promoter, whereas H-NS interacts specifically with a region extending from the grlA core promoter into its coding sequence. Together, these findings provide new insights into the environmental regulation and differential expressions of the grlR and grlA genes of C. rodentium. doi: 10.1128/JB.01540-09

Published
2010

21. Characterisation of atypical enteropathogenic E. coli strains of clinical origin

Author

Tennant Sharon M, Tauschek Marija, Azzopardi Kristy, Bigham Andrea, Bennett-Wood Vicki, Hartland Elizabeth L, Qi Weihong, Whittam Thomas S, and Robins-Browne Roy M

Subjects
Microbiology, QR1-502
Abstract

Abstract Background Enteropathogenic E. coli (EPEC) is a prominent cause of diarrhoea, and is characterised in part by its carriage of a pathogenicity island: the locus for enterocyte effacement (LEE). EPEC is divided into two subtypes according to the presence of bundle-forming pili (BFP), a fimbrial adhesin that is a virulence determinant of typical EPEC (tEPEC), but is absent from atypical EPEC (aEPEC). Because aEPEC lack BFP, their virulence has been questioned, as they may represent LEE-positive Shiga toxin-producing E. coli (STEC) that have lost the toxin-encoding prophage, or tEPEC that have lost the genes for BFP. To determine if aEPEC isolated from humans in Australia or New Zealand fall into either of these categories, we undertook phylogenetic analysis of 75 aEPEC strains, and compared them with reference strains of EPEC and STEC. We also used PCR and DNA hybridisation to determine if aEPEC carry virulence determinants that could compensate for their lack of BFP. Results The results showed that aEPEC are highly heterogeneous. Multilocus sequence typing revealed that 61 of 75 aEPEC strains did not belong to known tEPEC or STEC clades, and of those that did, none expressed an O:H serotype that is frequent in tEPEC or STEC strains associated with disease. PCR for each of 18 known virulence-associated determinants of E. coli was positive in less than 15% of strains, apart from NleB which was detected in 30%. Type I fimbriae were expressed by all aEPEC strains, and 12 strains hybridised with DNA probes prepared from either bfpA or bfpB despite being negative in the PCR for bfpA. Conclusion Our findings indicate that clinical isolates of aEPEC obtained from patients in Australia or New Zealand are not derived from tEPEC or STEC, and suggest that functional equivalents of BFP and possibly type I fimbriae may contribute to the virulence of some aEPEC strains.

Published
2009
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22. Characterisation of Shiga toxin-producing Escherichia coli O157 strains isolated from humans in Argentina, Australia and New Zealand

Author

Robins-Browne Roy M, Tennant Sharon M, Azzopardi Kristy, Espinosa Estela M, Chinen Isabel, Miliwebsky Elizabeth S, Leotta Gerardo A, and Rivas Marta

Subjects
Microbiology, QR1-502
Abstract

Abstract Background Shiga toxin-producing Escherichia coli (STEC) is an important cause of bloody diarrhoea (BD), non-bloody diarrhoea (NBD) and the haemolytic uraemic syndrome (HUS). In Argentina and New Zealand, the most prevalent STEC serotype is O157:H7, which is responsible for the majority of HUS cases. In Australia, on the other hand, STEC O157:H7 is associated with a minority of HUS cases. The main aims of this study were to compare the phenotypic and genotypic characteristics of STEC O157 strains isolated between 1993 and 1996 from humans in Argentina, Australia and New Zealand, and to establish their clonal relatedness. Results Seventy-three O157 STEC strains, isolated from HUS (n = 36), BD (n = 20), NBD (n = 10), or unspecified conditions (n = 7) in Argentina, Australia and New Zealand, were analysed. The strains were confirmed to be E. coli O157 by biochemical tests and serotyping. A multiplex polymerase chain reaction (PCR) was used to amplify the stx1, stx2 and rfbO157 genes and a genotyping method based on PCR-RFLP was used to determine stx1 and stx2 variants. This analysis revealed that the most frequent stx genotypes were stx2/stx2c (vh-a) (91%) in Argentina, stx2 (89%) in New Zealand, and stx1/stx2 (30%) in Australia. No stx1-postive strains were identified in Argentina or New Zealand. All strains harboured the eae gene and 72 strains produced enterohaemolysin (EHEC-Hly). The clonal relatedness of strains was investigated by phage typing and pulsed-field gel electrophoresis (PFGE). The most frequent phage types (PT) identified in Argentinian, Australian, and New Zealand strains were PT49 (n = 12), PT14 (n = 9), and PT2 (n = 15), respectively. Forty-six different patterns were obtained by XbaI-PFGE; 37 strains were grouped in 10 clusters and 36 strains showed unique patterns. Most clusters could be further subdivided by BlnI-PFGE. Conclusion STEC O157 strains isolated in Argentina, Australia, and New Zealand differed from each other in terms of stx-genotype and phage type. Additionally, no common PFGE patterns were found in strains isolated in the three countries. International collaborative studies of the type reported here are needed to detect and monitor potentially hypervirulent STEC clones.

Published
2008
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23. Prospective Surveillance of Pediatric Invasive Group AStreptococcusInfection

Author

Ching, Natasha S, primary, Crawford, Nigel, additional, McMinn, Alissa, additional, Baker, Ciara, additional, Azzopardi, Kristy, additional, Brownlee, Kate, additional, Lee, Donna, additional, Gibson, Margaret, additional, Smeesters, Pierre, additional, Gonis, Gena, additional, Ojaimi, Samar, additional, Buttery, Jim, additional, and Steer, Andrew C, additional

Published
2017
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25. Prospective Surveillance of Pediatric Invasive Group A Streptococcus Infection.

Author

Ching, Natasha S, Crawford, Nigel, McMinn, Alissa, Baker, Ciara, Azzopardi, Kristy, Brownlee, Kate, Lee, Donna, Gibson, Margaret, Smeesters, Pierre, Gonis, Gena, Ojaimi, Samar, Buttery, Jim, and Steer, Andrew C

Subjects
LONGITUDINAL method, PUBLIC health surveillance, STREPTOCOCCAL diseases, SEVERITY of illness index, DESCRIPTIVE statistics, SEQUENCE analysis, EVALUATION, SYMPTOMS, CHILDREN
Abstract

Background Invasive group A Streptococcus (GAS) disease has an incidence in high-income countries of 3 to 5 per 100000 per annum and a case-fatality ratio of 10% to 15%. Although these rates are comparable to those of invasive meningococcal disease in Australia before vaccine introduction, invasive GAS disease currently requires reporting in only 2 jurisdictions. Methods Data were collected prospectively through active surveillance at the Royal Children's Hospital, Melbourne (October 2014 to September 2016). Isolation of GAS from a sterile site was required for inclusion. Comprehensive demographic and clinical data were collected, and emm typing was performed on all isolates. Disease was considered severe if the patient required inotropic support or mechanical ventilation. Results We recruited 28 patients. The median age of the patients was 3.5 years (range, 4 days to 11 years). Ten (36%) patients had severe disease. Fifteen (54%) children had presented to a medical practitioner for review in the 48 hours before their eventual admission, including 7 of the 10 patients with severe GAS infection. Complications 6 months after discharge persisted in 21% of the patients. emm1 was the most common emm type (29%). Conclusion We found considerable short- and longer-term morbidity associated with pediatric invasive GAS disease in our study. Disease manifestations were frequently severe, and more than one-third of the patients required cardiorespiratory support. More than one-half of the patients attended a medical practitioner for assessment but were discharged in the 48-hour period before admission, which suggests that there might have been a window for earlier diagnosis. Our methodology was easy to implement as a surveillance system. [ABSTRACT FROM AUTHOR]

Published
2019
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26. The Type II Secretion System and Its Ubiquitous Lipoprotein Substrate, SslE, Are Required for Biofilm Formation and Virulence of Enteropathogenic Escherichia coli

Author

Baldi, Deborah L., primary, Higginson, Ellen E., additional, Hocking, Dianna M., additional, Praszkier, Judyta, additional, Cavaliere, Rosalia, additional, James, Catherine E., additional, Bennett-Wood, Vicki, additional, Azzopardi, Kristy I., additional, Turnbull, Lynne, additional, Lithgow, Trevor, additional, Robins-Browne, Roy M., additional, Whitchurch, Cynthia B., additional, and Tauschek, Marija, additional

Published
2012
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30. Distribution of tccP in Clinical Enterohemorrhagic and Enteropathogenic Escherichia coli Isolates

Author

Garmendia, Junkal, primary, Ren, Zhihong, additional, Tennant, Sharon, additional, Midolli Viera, Monica Aparecida, additional, Chong, Yuwen, additional, Whale, Andrew, additional, Azzopardi, Kristy, additional, Dahan, Sivan, additional, Sircili, Marcelo Palma, additional, Franzolin, Marcia Regina, additional, Trabulsi, Luiz R., additional, Phillips, Alan, additional, Gomes, Tânia A. T., additional, Xu, Jianguo, additional, Robins-Browne, Roy, additional, and Frankel, Gad, additional

Published
2005
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31. Characterisation of Shiga toxin-producing Escherichia coli O157 strains isolated from humans in Argentina, Australia and New Zealand.

Author

Leotta, Gerardo A., Miliwebsky, Elizabeth S., Chinen, Isabel, Espinosa, Estela M., Azzopardi, Kristy, Tennant, Sharon M., Robins-Browne, Roy M., and Rivas, Marta

Subjects
ESCHERICHIA coli, VEROCYTOTOXINS, DIARRHEA, HEMOLYTIC-uremic syndrome
Abstract

Background: Shiga toxin-producing Escherichia coli (STEC) is an important cause of bloody diarrhoea (BD), non-bloody diarrhoea (NBD) and the haemolytic uraemic syndrome (HUS). In Argentina and New Zealand, the most prevalent STEC serotype is O157:H7, which is responsible for the majority of HUS cases. In Australia, on the other hand, STEC O157:H7 is associated with a minority of HUS cases. The main aims of this study were to compare the phenotypic and genotypic characteristics of STEC O157 strains isolated between 1993 and 1996 from humans in Argentina, Australia and New Zealand, and to establish their clonal relatedness. Results: Seventy-three O157 STEC strains, isolated from HUS (n = 36), BD (n = 20), NBD (n = 10), or unspecified conditions (n = 7) in Argentina, Australia and New Zealand, were analysed. The strains were confirmed to be E. coli O157 by biochemical tests and serotyping. A multiplex polymerase chain reaction (PCR) was used to amplify the stx1, stx2 and rfbO157 genes and a genotyping method based on PCR-RFLP was used to determine stx1 and stx2 variants. This analysis revealed that the most frequent stx genotypes were stx2/stx2c (vh-a) (91%) in Argentina, stx2 (89%) in New Zealand, and stx1/stx2 (30%) in Australia. No stx1-postive strains were identified in Argentina or New Zealand. All strains harboured the eae gene and 72 strains produced enterohaemolysin (EHEC-Hly). The clonal relatedness of strains was investigated by phage typing and pulsed-field gel electrophoresis (PFGE). The most frequent phage types (PT) identified in Argentinian, Australian, and New Zealand strains were PT49 (n = 12), PT14 (n = 9), and PT2 (n = 15), respectively. Forty-six different patterns were obtained by XbaI-PFGE; 37 strains were grouped in 10 clusters and 36 strains showed unique patterns. Most clusters could be further subdivided by BlnI-PFGE. Conclusion: STEC O157 strains isolated in Argentina, Australia, and New Zealand differed from each other in terms of stx-genotype and phage type. Additionally, no common PFGE patterns were found in strains isolated in the three countries. International collaborative studies of the type reported here are needed to detect and monitor potentially hypervirulent STEC clones. [ABSTRACT FROM AUTHOR]

Published
2008
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32. Contribution of the pst-phoUOperon to Cell Adherence by Atypical Enteropathogenic Escherichia coliand Virulence of Citrobacter rodentium

Author

Cheng, Catherine, Tennant, Sharon M., Azzopardi, Kristy I., Bennett-Wood, Vicki, Hartland, Elizabeth L., Robins-Browne, Roy M., and Tauschek, Marija

Abstract

ABSTRACTStrains of enteropathogenic Escherichia coli(EPEC) generally employ the adhesins bundle-forming pili (Bfp) and intimin to colonize the intestine. Atypical EPEC strains possess intimin but are negative for Bfp and, yet, are able to cause disease. To identify alternative adhesins to Bfp in atypical EPEC, we constructed a transposon mutant library of atypical EPEC strain E128012 (serotype O114:H2) using TnphoA. Six mutants that had lost the ability to adhere to HEp-2 cells were identified, and in all six mutants TnphoAhad inserted into the pstSCAB-phoU(Pst) operon. To determine if the Pst operon is required for adherence, we used site-directed mutagenesis to construct a pstCAmutant of E128012. The resultant mutant showed a reduced ability to adhere to HEp-2 cells and T84 intestinal epithelial cells, which was restored by trans-complementation with intact pstCA. To determine if pstcontributes to bacterial colonization in vivo, a pstCAmutation was made in the EPEC-like murine pathogen, Citrobacter rodentium. C57BL/6 mice infected perorally with the pstCAmutant of C. rodentiumexcreted significantly lower numbers of C. rodentiumthan those given the wild-type strain. Moreover, colonic hyperplasia and diarrhea, which are features of infections with C. rodentium, were not observed in mice infected with the pstCAmutant but did occur in mice given the trans-complemented mutant. As mutations in pstgenes generally lead to constitutive expression of the Pho regulon, our findings suggested that the Pho regulon may contribute to the reduced virulence of the pstCAmutants. To investigate this, we inactivated phoBin the pstCAmutants of EPEC E128012 and C. rodentiumand found that the phoBmutation restored the adherent phenotype of both mutant strains. These results demonstrate that Pst contributes to the virulence of atypical EPEC and C. rodentium, probably by causing increased expression of an unidentified, Pho-regulated adhesin.

Published
2009
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33. Distribution of tccPin Clinical Enterohemorrhagic and Enteropathogenic Escherichia coliIsolates

Author

Garmendia, Junkal, Ren, Zhihong, Tennant, Sharon, Midolli Viera, Monica Aparecida, Chong, Yuwen, Whale, Andrew, Azzopardi, Kristy, Dahan, Sivan, Sircili, Marcelo Palma, Franzolin, Marcia Regina, Trabulsi, Luiz R., Phillips, Alan, Gomes, Ta^nia A. T., Xu, Jianguo, Robins-Browne, Roy, and Frankel, Gad

Abstract

ABSTRACTEnterohemorrhagic Escherichia coli(EHEC) and enteropathogenic E. coli(EPEC) are diarrheagenic pathogens that colonize the gut through the formation of attaching and effacing lesions, which depend on the translocation of effector proteins via a locus of enterocyte effacement-encoded type III secretion system. Recently, two effector proteins, EspJ and TccP, which are encoded by adjacent genes on prophage CP-933U in EHEC O157:H7, have been identified. TccP consists of a unique N-terminus region and several proline-rich domains. In this project we determined the distribution of tccPin O157:H7, in non-O157 EHEC, and in typical and atypical EPEC isolates. All the EHEC O157:H7 strains tested were tccP+. Unexpectedly, tccPwas also found in non-O157 EHEC, and in typical and atypical EPEC isolates, particularly in strains belonging to serogroups O26 (EHEC), O119 (typical EPEC), and O55 (atypical EPEC). We recorded some variation in the length of tccP, which reflects diversity in the number of the proline-rich repeats. These results show the existence of a class of “attaching and effacing” pathogens which express a combination of EPEC and EHEC virulence determinants.

Published
2005
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34. A Modular Approach to Assembly of Totally Synthetic Self-adjuvanting Lipopeptide-based Vaccines Allows Conformational Epitope Building.

Author

Weiguang Zeng, Horrocks, Kylie J., Robevska, Gorjana, Chinn Yi Wong, Azzopardi, Kristy, Tauschek, Marija, Robins-Browne, Roy M., and Jackson, David C.

Subjects
*SYNTHETIC vaccines, *EPITOPES, *AMINO acid sequence, *CELLULAR immunity, *ESCHERICHIA coli, *INFLUENZA vaccines, *ENTEROTOXINS, *T cells
Abstract

The technology described here allows the chemical synthesis of vaccines requiring correctly folded epitopes and that contain difficult or long peptide sequences. The final self-adjuvanting product promotes strong humoral and/or cell-mediated immunity. A module containing common components of the vaccine (T helper cell epitope and the adjuvanting lipid moiety S-[2,3-bis(palmitoyloxy)propyl]cysteine) was assembled to enable a plug and play approach to vaccine assembly. The inclusion within the module of a chemical group with chemical properties complementary and orthogonal to a chemical group present in the target epitope allowed chemoselective ligation of the two vaccine components. The heat-stable enterotoxin of enterotoxigenic Escherichia coil that requires strict conformational integrity for biological activity and the reproductive hormone luteinizing hormone-releasing hormone were used as the target epitopes for the antibody vaccines. An epitope from the acid polymerase of influenza virus was used to assemble a CD8+ T cell vaccine. Evaluation of each vaccine candidate in animals demonstrated the feasibility of the approach and that the type of immune response required, viz, antibody or cytotoxic T lymphocyte, dictates the nature of the chemical linkage between the module and target epitope. The use of a thioether bond between the module and target epitope had little or no adverse effect on antibody responses, whereas the use of a disulfide bond between the module and target epitope almost completely abrogated the antibody response. In contrast, better cytotoxic T lymphocyte responses were obtained when a disulfide bond was used. [ABSTRACT FROM AUTHOR]

Published
2011
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