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41 results on '"Sanchez, Amparo"'

1. Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial

Author

Aix, Santiago Ponce, Ciuleanu, Tudor Eliade, Navarro, Alejandro, Cousin, Sophie, Bonanno, Laura, Smit, Egbert F, Chiappori, Alberto, Olmedo, Maria Eugenia, Horvath, Ildiko, Grohé, Christian, Farago, Anna F, López-Vilariño, José Antonio, Cullell-Young, Martin, Nieto, Antonio, Vasco, Noelia, Gómez, Javier, Kahatt, Carmen, Zeaiter, Ali, Carcereny, Enric, Roubec, Jaromir, Syrigos, Konstantinos, Lo, Gregory, Barneto, Isidoro, Pope, Anthony, Sánchez, Amparo, Kattan, Joseph, Zarogoulidis, Konstantinos, Waller, Cornelius F, Bischoff, Helge, Juan-Vidal, Oscar, Reinmuth, Niels, Dómine, Manuel, and Paz-Ares, Luis

Published
2023
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2. Brief Report: Updated Data From IMscin001 Part 2, a Randomized Phase III Study of Subcutaneous Versus Intravenous Atezolizumab in Patients With Locally Advanced/Metastatic NSCLC

Author

Burotto, Mauricio, primary, Zvirbule, Zanete, additional, Alvarez, Renzo, additional, Chewaskulyong, Busayamas, additional, Herraez-Baranda, Luis A., additional, Shearer-Kang, Esther, additional, Liu, Xiaoyan, additional, Tosti, Nadia, additional, Williams, Patrick, additional, Castro Sanchez, Amparo Yovanna, additional, Zanghi, James, additional, and Felip, Enriqueta, additional

Published
2024
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4. Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial

Author

Martínez de Soto, Lucía, Rodríguez Mariblanca, Amelia, Díaz García, Lucía, Ramírez García, Elena, Seco Meseguer, Enrique, Stewart Balbás, Stefan Mark, Marín Candón, Alicia, García García, Irene, Urroz Elizalde, Mikel, Monserrat Villatoro, Jaime, de la Rosa, Paula, Sanz García, Marta, López Crespo, Cristina, Mauleón Martínez, Vega, de Madariaga Castell, Raquel, Vitón Vara, Laura, García Rodríguez, Julio, Buño, Antonio, López Granados, Eduardo, Cámara, Carmen, Rey Cuevas, Esther, Ayllon García, Pilar, Jiménez González, María, Hernández Rubio, Victoria, Moraga Alapont, Paloma, Sánchez, Amparo, Prieto, Rocío, Llorente Gómez, Silvia, Miragall Roig, Cristina, Aparicio Marlasca, Marina, de la Calle, Fernando, Arsuaga, Marta, Duque, Blanca, Meijide, Susana, García de Vicuña, Aitor, Santorcuato, Ana, Expósito, Iraide, de Benito, Sara, Andia, Joseba, Castillo, Cristina, Irurzun, Esther, Camino, Jesús, Temprano, Mikel, Goikoetxea, Josune, Bustinza, Alazne, Larrea, Maialen, Gallego, Mikel, García-Vázquez, Dolores, de la Hoz, Ana Belén, Pérez-Nanclares, Gustavo, Pérez-Guzmán, Estíbaliz, Idoyaga, Eneko, Lamela, Adriana, Oteo, Jesús, Castillo de la Osa, María, Hernández Gutiérrez, Lourdes, Andrés Galván, María Elena, Calonge, Esther, Bermejo, Mercedes, de la Torre-Tarazona, Erick Humberto, Cascajero, Almudena, Fedele, Giovanni, Perea, Concepción, Cervera, Isabel, Bodega-Mayor, Irene, Montes-Casado, María, Portolés, Pilar, Baranda, Jana, Granés, Laura, Lazaar, Sulayman, Herranz, Sara, Mellado, María Eugènia, Tortajada, Marta, Malet, Montserrat, Quesada, Sebastiana, Vilella, Anna, Llupià, Anna, Olivé, Victoria, Trilla, Antoni, Gómez, Begoña, González, Elisenda, Romero, Sheila, Gámez, Francisco Javier, Casals, Cristina, Burunat, Laura, Castelló, Juan José, Fernández, Patricia, Bedini, Josep Lluís, Vila, Jordi, Aguilar, Carla, Altadill, Carmen, Armadans, Lluis, Borras-Bermejo, Blanca, Calonge, Julia, Camacho, Lina, Feliu, Anna, Gili, Gisela, Llorente, Cesar, Martínez-Gómez, Xavier, Otero-Romero, Susana, Palacio, Esther, Parés, Oleguer, Pinós, Laia, Plaza, Aitana, Riera-Arnau, Judit, Rodrigo-Pendás, José Angel, Sans, Carla, Santos, José, Torres, Gloria, Torrens, Margarita, Uriona, Sonia, Ballarin Alins, Elena, Pérez Esquirol, Eulàlia, Vendrell Bosch, Lourdes, Laredo Velasco, Leonor, Uribe López, Diana, González Rojano, Esperanza, Sánchez-Craviotto, Manuel, Rivas Paterna, Ana Belén, Hernán-Gómez, Teresa Iglesias, Rodríguez Galán, Natalia, Gil Marín, José Antonio, Álvarez-Morales, Verónica, Navalpotro, Ana Belén, Jiménez-Santamaría, M Dolores, Cardós, M Carmen, Hermoso, Elena, García-Arenillas, Mar, Pérez Macías, Natalia, Domingo Fernández, Alexandra, López Picado, Amanda, Quiñones, Jorge Mario, Deidda, Nicoletta, García-Franco, Ana, Torvisco, José María, Borobia, Alberto M, Carcas, Antonio J, Pérez-Olmeda, Mayte, Castaño, Luis, Bertran, María Jesús, García-Pérez, Javier, Campins, Magdalena, Portolés, Antonio, González-Pérez, María, García Morales, María Teresa, Arana-Arri, Eunate, Aldea, Marta, Díez-Fuertes, Francisco, Fuentes, Inmaculada, Ascaso, Ana, Lora, David, Imaz-Ayo, Natale, Barón-Mira, Lourdes E, Agustí, Antonia, Pérez-Ingidua, Carla, Gómez de la Cámara, Agustín, Arribas, José Ramón, Ochando, Jordi, Alcamí, José, Belda-Iniesta, Cristóbal, and Frías, Jesús

Published
2021
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5. Assessing the impact of digital patient monitoring on health outcomes and healthcare resource usage in addition to the feasibility of its combination with at-home treatment, in participants receiving systemic anticancer treatment in clinical practice: protocol for an interventional, open-label, multicountry platform study (ORIGAMA)

Author

Iivanainen, Sanna, primary, Baird, Anne-Marie, additional, Balas, Bogdana, additional, Bustillos, Alberto, additional, Castro Sanchez, Amparo Yovanna, additional, Eicher, Manuela, additional, Golding, Sophie, additional, Mueller-Ohldach, Mathis, additional, Reig, Maria, additional, Welslau, Manfred, additional, and Ammann, Johannes, additional

Published
2023
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16. Obtaining EQ-5D-5L utilities from the disease specific quality of life Alzheimer's disease scale: development and results from a mapping study

Author

Rombach, Ines, Iftikhar, Marvi, Jhuti, Gurleen S., Gustavsson, Anders, Lecomte, Pascal, Belger, Mark, Handels, Ron, Castro Sanchez, Amparo Y., Kors, Jan, Hopper, Louise, Olde Rikkert, Marcel, Selbæk, Geir, Stephan, Astrid, Sikkes, Sietske A. M., Woods, Bob, Gonçalves-Pereira, Manuel, Zanetti, Orazio, Ramakers, Inez H. G. B., Verhey, Frans R. J., Gallacher, John, Actifcare Consortium, LeARN Consortium, Landeiro, Filipa, Gray, Alastair M., Psychiatrie & Neuropsychologie, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Psychiatrie (9), Neurology, and Amsterdam Neuroscience - Neurodegeneration

Subjects
Male, Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1], Mean squared error, Scale (ratio), Computer science, Preference based measures, PATIENT, Article, VALIDATION, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Alzheimer Disease, EQ-5D, PEOPLE, Surveys and Questionnaires, Statistics, medicine, Humans, Dementia, Health related quality of life, 030212 general & internal medicine, DEMQOL, Mapping algorithm, ADAPTATION, VERSION, PROXY, Multinomial logistic regression, Estimation, 030503 health policy & services, DEMENTIA, Public Health, Environmental and Occupational Health, Statistical model, OUTCOME MEASURES, medicine.disease, Cross-walking, humanities, Quality of Life, Female, 0305 other medical science, Algorithms
Abstract

Purpose The Quality of Life Alzheimer’s Disease Scale (QoL-AD) is commonly used to assess disease specific health-related quality of life (HRQoL) as rated by patients and their carers. For cost-effectiveness analyses, utilities based on the EQ-5D are often required. We report a new mapping algorithm to obtain EQ-5D indices when only QoL-AD data are available. Methods Different statistical models to estimate utility directly, or responses to individual EQ-5D questions (response mapping) from QoL-AD, were trialled for patient-rated and proxy-rated questionnaires. Model performance was assessed by root mean square error and mean absolute error. Results The response model using multinomial regression including age and sex, performed best in both the estimation dataset and an independent dataset. Conclusions The recommended mapping algorithm allows researchers for the first time to estimate EQ-5D values from QoL-AD data, enabling cost-utility analyses using datasets where the QoL-AD but no utility measures were collected.

Published
2021

20. Systematic literature review of methodologies and data sources of existing economic models across the full spectrum of Alzheimer’s disease and dementia from apparently healthy through disease progression to end of life care: a systematic review protocol.

Author

Karagiannidou, Maria, primary, Wittenberg, Raphael, additional, Landeiro, Filipa Isabel Trigo, additional, Park, A-La, additional, Fry, Andra, additional, Knapp, Martin, additional, Gray, Alastair M, additional, Tockhorn-Heidenreich, Antje, additional, Castro Sanchez, Amparo Yovanna, additional, Ghinai, Isaac, additional, Handels, Ron, additional, Lecomte, Pascal, additional, and Wolstenholme, Jane, additional

Published
2018
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29. Mathematical and statistical models applied to HIV and Hepatitis C co-infection and to nosocomial infections

Author

Castro Sanchez, Amparo Yovanna, Aerts, Marc, and Hens, Niel

Abstract

In dit proefschrift worden diverse statistische en wiskundige modellen voor HIV en HCV co-infectie en voor nosocomiale infecties gepresenteerd. De modellen werden toegepast op vier verschillende studies, rekening houdend met de doelstellingen en kenmerken van elk onderzoek. This thesis presents several statistical and mathematical models applied to HIV and HCV co-infection and to nosocomial infections. The models were applied to four different studies, taking into account the objectives and characteristics of each of the studies. Regarding the statistical methods we focus on those applied to type II intervalcensored data. We include an overview of existing methods and software availability to analyse this type of data.

Published
2014

30. Obstructive sleep apnea and diabetes mellitus

Author

Vale, Jorge, primary, Manuel, Paula, additional, Oliveira, Eurico, additional, Oliveira, Ana Rita, additional, Silva, Eloisa, additional, Melo, Vitor, additional, Sousa, Marta, additional, Alexandre, João Carlos, additional, Gil, Isabel, additional, Sanchez, Amparo, additional, Nascimento, Edite, additional, and Torres, António Simões, additional

Published
2015
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32. EFECTOS RESPIRATORIOS Y SOMATOMÉTRICOS EN RECIÉN NACIDOS PRETÉRMINO CUYAS MADRES RECIBIERON CORTICOTERAPIA DE ESQUEMA MÚLTIPLE VERSUS ÚNICO EN EL SERVICIO DE OBSTETRICIA DEL HOSPITAL REGIONAL HONORIO DELGADO ESPINOZA EN EL AÑO 2013

Author

CHOQUE SANCHEZ, AMPARO and CHOQUE SANCHEZ, AMPARO

Abstract

EFECTO DE LOS CORTICOIDES SOBRE LA MADURACIÓN PULMONAR FETAL INTRODUCCIÓN PARTO PRETÉRMINO PROMOCIÓN DE LA MADURACIÓN PULMONAR HISTORIA DE LOS CORTICOSTEROIDES PRENATALES DESARROLLO PULMONAR FARMACOLOGÍA Y FISIOLOGÍA DE LOS CORTICOSTEROIDES PRENATALES RIESGOS Y BENEFICIOS DE UN CICLO ÚNICO DE CORTICOSTEROIDES PRENATALES RIESGOS Y BENEFICIOS DE CURSOS REPETIDOS DE CORTICOIDES PRENATALES RIESGOS Y BENEFICIOS DE LOS CURSOS DE RESCATE DE CORTICOIDES PRENATALES EN HUMANOS RIESGOS Y BENEFICIOS A LARGO PLAZO DE LOS CURSOS REPETIDOS DE CORTICOIDES PRENATALES RESULTADOS CARACTERÍSTICAS DEMOGRÁFICAS DE LAS PACIENTES EN AMBOS GRUPOS PARIDAD DE LAS PACIENTES EN AMBOS GRUPOS EDAD GESTACIONAL DE LAS PACIENTES EN AMBOS GRUPOS RESULTADOS CLÍNICOS DE LA TERAPIA CON CORTICOIDES PRENATALES EN AMBOS GRUPOS RESULTADOS CLÍNICOS DE LA TERAPIA CON CORTICOIDES PRENATALES EN AMBOS GRUPOS CON RELACIÓN A PESO RESULTADOS CLÍNICOS DE LA TERAPIA CON CORTICOIDES PRENATALES EN AMBOS GRUPOS CON RELACIÓN A TALLA RESULTADOS CLÍNICOS DE LA TERAPIA CON CORTICOIDES PRENATALES EN AMBOS GRUPOS CON RELACIÓN A PERÍMETRO CEFÁLICO

Published
2014

37. Systematic literature review of methodologies and data sources of existing economic models across the full spectrum of Alzheimer’s disease and dementia from apparently healthy through disease progression to end of life care: a systematic review protocol

Author

Karagiannidou, Maria, Wittenberg, Raphael, Landeiro, Filipa Isabel Trigo, Park, A-La, Fry, Andra, Knapp, Martin, Gray, Alastair, Tockhorn-Heidenreich, Antje, Sanchez, Amparo Yovanna Castro, Ghinai, Isaac, Handels, Ron, Lecomte, Pascal, Wolstenholme, Jane, Karagiannidou, Maria, Wittenberg, Raphael, Landeiro, Filipa Isabel Trigo, Park, A-La, Fry, Andra, Knapp, Martin, Gray, Alastair, Tockhorn-Heidenreich, Antje, Sanchez, Amparo Yovanna Castro, Ghinai, Isaac, Handels, Ron, Lecomte, Pascal, and Wolstenholme, Jane

Abstract

Introduction Dementia is one of the greatest health challenges the world will face in the coming decades, as it is one of the principal causes of disability and dependency among older people. Economic modelling is used widely across many health conditions to inform decisions on health and social care policy and practice. The aim of this literature review is to systematically identify, review and critically evaluate existing health economics models in dementia. We included the full spectrum of dementia, including Alzheimer’s disease (AD), from preclinical stages through to severe dementia and end of life. This review forms part of the Real world Outcomes across the Alzheimer’s Disease spectrum for better care: multimodal data Access Platform (ROADMAP) project. Methods and analysis Electronic searches were conducted in Medical Literature Analysis and Retrieval System Online, Excerpta Medica dataBASE, Economic Literature Database, NHS Economic Evaluation Database, Cochrane Central Register of Controlled Trials, Cost-Effectiveness Analysis Registry, Research Papers in Economics, Database of Abstracts of Reviews of Effectiveness, Science Citation Index, Turning Research Into Practice and Open Grey for studies published between January 2000 and the end of June 2017. Two reviewers will independently assess each study against predefined eligibility criteria. A third reviewer will resolve any disagreement. Data will be extracted using a predefined data extraction form following best practice. Study quality will be assessed using the Phillips checklist for decision analytic modelling. A narrative synthesis will be used. Ethics and dissemination The results will be made available in a scientific peer-reviewed journal paper, will be presented at relevant conferences and will also be made available through the ROADMAP project.

40. Obtaining EQ-5D-5L utilities from the disease specific quality of life Alzheimer's disease scale: development and results from a mapping study.

Author

Rombach, Ines, Iftikhar, Marvi, Jhuti, Gurleen S, Gustavsson, Anders, Lecomte, Pascal, Belger, Mark, Handels, Ron, Castro Sanchez, Amparo Y, Kors, Jan, Hopper, Louise, Olde Rikkert, Marcel, Selbæk, Geir, Stephan, Astrid, Sikkes, Sietske A M, Woods, Bob, Gonçalves-Pereira, Manuel, Zanetti, Orazio, Ramakers, Inez H G B, Verhey, Frans R J, and Gallacher, John

Abstract

Purpose: The Quality of Life Alzheimer's Disease Scale (QoL-AD) is commonly used to assess disease specific health-related quality of life (HRQoL) as rated by patients and their carers. For cost-effectiveness analyses, utilities based on the EQ-5D are often required. We report a new mapping algorithm to obtain EQ-5D indices when only QoL-AD data are available.Methods: Different statistical models to estimate utility directly, or responses to individual EQ-5D questions (response mapping) from QoL-AD, were trialled for patient-rated and proxy-rated questionnaires. Model performance was assessed by root mean square error and mean absolute error.Results: The response model using multinomial regression including age and sex, performed best in both the estimation dataset and an independent dataset.Conclusions: The recommended mapping algorithm allows researchers for the first time to estimate EQ-5D values from QoL-AD data, enabling cost-utility analyses using datasets where the QoL-AD but no utility measures were collected. [ABSTRACT FROM AUTHOR]

Published
2020
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41. Obtaining EQ-5D-5L utilities from the disease specific quality of life Alzheimer's disease scale: development and results from a mapping study.

Author

Rombach I, Iftikhar M, Jhuti GS, Gustavsson A, Lecomte P, Belger M, Handels R, Castro Sanchez AY, Kors J, Hopper L, Olde Rikkert M, Selbæk G, Stephan A, Sikkes SAM, Woods B, Gonçalves-Pereira M, Zanetti O, Ramakers IHGB, Verhey FRJ, Gallacher J, Actifcare Consortium, LeARN Consortium, Landeiro F, and Gray AM

Subjects
Algorithms, Female, Humans, Male, Surveys and Questionnaires, Alzheimer Disease psychology, Quality of Life psychology
Abstract

Purpose: The Quality of Life Alzheimer's Disease Scale (QoL-AD) is commonly used to assess disease specific health-related quality of life (HRQoL) as rated by patients and their carers. For cost-effectiveness analyses, utilities based on the EQ-5D are often required. We report a new mapping algorithm to obtain EQ-5D indices when only QoL-AD data are available., Methods: Different statistical models to estimate utility directly, or responses to individual EQ-5D questions (response mapping) from QoL-AD, were trialled for patient-rated and proxy-rated questionnaires. Model performance was assessed by root mean square error and mean absolute error., Results: The response model using multinomial regression including age and sex, performed best in both the estimation dataset and an independent dataset., Conclusions: The recommended mapping algorithm allows researchers for the first time to estimate EQ-5D values from QoL-AD data, enabling cost-utility analyses using datasets where the QoL-AD but no utility measures were collected.

Published
2021
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