Search

Your search keyword '"Yasuhiro Akai"' showing total 13 results
Start Over Author "Yasuhiro Akai" Publisher s. karger ag
13 results on '"Yasuhiro Akai"'

1. Anti-Centromere Antibody Positivity in a Patient with Generalized Morphea

Author

Anna Nakajima, Yasuhiro Akai, Hideo Asada, and Fumi Miyagawa

Subjects
Skin manifestations, Pathology, medicine.medical_specialty, biology, integumentary system, business.industry, Single Case, Dermatology, lcsh:RL1-803, medicine.disease, Generalized morphea, Centromere antibody, medicine, biology.protein, lcsh:Dermatology, Systemic sclerosis, Antibody, Skin lesion, business, skin and connective tissue diseases, Generalized scleroderma, Anti-centromere antibody, Morphea
Abstract

We report the case of a 45-year-old female with generalized morphea (GM), who exhibited positivity for the anti-centromere antibody (Ab). She frequently developed multiple sclerotic skin lesions, whose histological findings were compatible with morphea. She demonstrated favorable responses to topical and oral steroids. Cases of GM associated with systemic sclerosis (SSc)-specific Abs (anti-Scl-70 Ab, anti-centromere Ab, and anti-RNA polymerase III Ab) have rarely been reported. The previously reported GM cases involving anti-SSc-specific Abs exhibited some skin manifestations of SSc, such as nailfold capillary changes. However, our case did not show any signs of SSc or limited cutaneous SSc. More cases are needed to clarify whether GM with SSc-specific Abs leads to SSc.

Published
2018

2. Angiogenic Factors and Risks of Technique Failure and Cardiovascular Events in Patients Receiving Peritoneal Dialysis

Author

Katsuhiko Morimoto, Ken-ichi Samejima, Kenji Onoue, Yasuhiro Akai, Satoshi Okayama, Hiroyuki Okura, Yoshihiko Saito, Masaru Matsui, Yukiji Takeda, Hiroyuki Kawata, Miho Tagawa, and Rika Kawakami

Subjects
Placental growth factor, Original Paper, business.industry, Urology, medicine.medical_treatment, 030232 urology & nephrology, Vascular Endothelial Growth Factor Family, 030204 cardiovascular system & hematology, Peritoneal dialysis, 03 medical and health sciences, 0302 clinical medicine, Cytokine, embryonic structures, Immunology, Medicine, In patient, Cardiology and Cardiovascular Medicine, business, Soluble fms-like tyrosine kinase-1
Abstract

Background: Placental growth factor (PlGF) is a member of the vascular endothelial growth factor family that acts as a pleiotropic cytokine capable of stimulating angiogenesis and accelerating atherogenesis. Soluble fms-like tyrosine kinase-1 (sFlt-1) antagonizes PlGF action. Higher levels of PlGF and sFlt-1 have been associated with cardiovascular events in patients with chronic kidney disease, yet little is known about their relationship with adverse outcomes in patients on peritoneal dialysis (PD). The aim of this study was to investigate the association of PlGF and sFlt-1 with technique survival and cardiovascular events. Methods: We measured serum levels of PlGF and plasma levels of sFlt-1 in 40 PD patients at Nara Medical University. Results: PlGF and sFlt-1 levels were significantly correlated with the dialysate-to-plasma ratio of creatinine (r = 0.342, p = 0.04 and r = 0.554, p < 0.001) although PlGF and sFlt-1 levels were not correlated with total creatinine clearance and total Kt/V. Additionally, both PlGF and sFlt-1 levels were significantly higher in patients with high transport membranes compared to those without (p = 0.039 and p < 0.001, respectively). Patients with PlGF levels above the median had lower technique survival and higher incidence of cardiovascular events than patients with levels below the median, with hazard ratios of 11.9 and 7.7, respectively, in univariate Cox regression analysis. However, sFlt-1 levels were not associated with technique survival or cardiovascular events (p = 0.11 and p = 0.10, respectively). Conclusion: Elevated PlGF and sFlt-1 are significantly associated with high transport membrane status. PlGF may be a useful predictor of technique survival and cardiovascular events in PD patients.

Published
2016

3. Contents Vol. 92, 2002

Author

Sun Woo Lim, Choung Soo Kim, Bertalan Fodor, Yukihiko Kawasaki, Hirofumi Matuoka, Tadao Oohara, Shozo Hosokawa, Y. Asano, Su-Kil Park, Izzet Yavuz, Yasuhide Nakashima, K. Tamba, E. Kusano, Jung Ho Cha, A. Concheiro Guisan, Seval Izdes, Giuseppe Rizzuto, Kaori Kanegae, Yasuo Imanishi, Sumiko Homma, Chul Woo Yang, Sadayoshi Ito, A. Sturiale, Müjdat Yenicesu, Toshiaki Makino, Cheri V. Barrett, Toshihiko Miwa, Yasuro Kumeda, Chin-Huang Chen, Nora Klenk, Chun-Cheng Hou, Hitoshi Suzuki, J. Charles Jennette, Cüneyt Ensari, Shoji Nogae, Won Seok Yang, Ju Young Jung, Ken Farrington, Massimino Senatore, Hitoshi Goto, Tülin Gümüş, Mükerrem Safali, Yi-Hong Chou, Yoshiyuki Tomiyoshi, Ottó Árkossy, Ronald J. Falk, Jorge Isaac, Gilbert Deray, Ruriko Nozawa, Gloria A. Preston, N. Frisina, Abdülgaffar Vural, Junzo Suzuki, Shigeru Nakai, Masaaki Inaba, Toshikatsu Shimizu, J.A. Camacho Diaz, Magdolna Aleksza, Wei-Ming Hsu, Akihiko Osajima, Magali Ciroldi, Petra Marchand, Erzsébet Ladányi, Hirofumi Anai, Sacit Turanli, Hyung Wook Kim, T. Rengarajan, Patrizia Colombo, M. Suzuki, Y. Watanabe, Wu-Chang Yang, Yasuhiro Akai, Masahito Tamura, F. Corica, Eri Muso, Koichiro Homma, L. Garcia Garcia, Jürgen Floege, Xixin Wu, Motoaki Miyazono, A. Gimenez Llort, Laurence Fardet, Motoshi Hattori, F. Floccari, Aquiles Jara, Yoshihiko Saito, Eveline Sowa, Zeki Odabaşi, Yoko Fujino, Song Lin, Vincent Launay-Vacher, Júlia Széll, Lee-Moi Thien, Silvia Pierangeli, Koji Harada, Jaime Pereira, Akane Kurisu, Nai-Phon Wang, Tomoko Nakamura, R. Ravichandran, Susumu Makino, Mária Takács, Marcela Vasquez, Masahiro Okazaki, Yuri Ozawa, Yong Soo Kim, G. Di Pasquale, Chiew H. Kong, A. Ruello, Hassane Izzedine, Takeshi Suda, Luigia Costantini, Itsuro Kazama, Tsen-Tsai Chen, A. Favaloro, A. Romeo, M. Sommer, Ryuichiro Konda, Hiroshi Shiraga, Hideo Nakai, Soon Bae Kim, J. Gerth, Michele Buemi, G. Anastasi, Oliviero Filiberti, Sándor Sipka, Tatsuya Nakatani, Takahiko Nagahama, Keiji Fujiwara, Kyoko Kitauchi, Masayuki Iwano, Narutoshi Kabashima, Satoru Kawaguchi, Takanobu Sakemi, Yasushi Asano, Carla Peona, Akira Owada, Satish M. Rao, Sigeyuki Takeda, Naoko Matsumoto, Jung Sik Park, Tsung-Hsiu Wang, Michiko Suzuki, Hidehiro Kakizaki, Masao Kanauchi, Aranka Koós, Iván Palomo, Yasuhiro Komatsu, Mari Michimata, Pasqualina Cecere, Kayser Caglar, Y. Oyama, Sang Koo Lee, Giovanna Piccini, Lin Shan, Deniz Ayli, O. Iimura, M. Buemi, Mitsunobu Matsubara, Takao Saruta, J. Vila Cots, Yee-Yung Ng, Katsuya Nonomura, Toru Shinzato, Eiji Kusano, Masako Iwamoto, G. Stein, Shigehisa Aoki, Masuhisa Nakamura, Takeshi Kanda, G. Cutroneo, U. Eismann, Qiu Mingcai, Toshio Hashimoto, Ulf Janssen, Masamiki Miwa, Susan L. Hogan, Takayuki Ota, Kosei Segawa, A. Vila Santandreu, Mayumi Nagata, Yutaka Imai, Omac Tufekcioglu, Yoshiyuki Matsuo, Heinfried H. Radeke, David A. Alcorta, An S. De Vriese, Takahiko Ono, Paik-Seong Lim, Gisho Honda, Arnold J. Felsenfeld, Katsumi Ito, Chang-Linct Yang, M. Imai, Yutaro Hayashi, Koichi Hayashi, Bum Soon Choi, C. Aloisi, Enikő Sárváry, Cecilia Chacón, Wan Young Kim, Marcelo Alarcón, Tsutomu Araki, Byung Kee Bang, Jin Kim, Huaji Chen, Shigeo Suzuki, Gabriella Lakos, Attila Nagy, Yoshiki Nishizawa, C. Ito, Can Li, Fuad S. Shihab, Yuujiro Watanabe, A O Phillips, Toshihiko Hata, Kenji Maeda, Lesley C Dinwiddie, Eiji Ishimura, Shin Suda, Antonio Nicoletti, Chui-Mei Tiu, Norio Kurumatani, Seung Hun Lee, and Ning Liu

Subjects
Traditional medicine, business.industry, Medicine, business
Published
2002

4. Subject Index Vol. 91, 2002

Author

Hiroyuki Sasamura, Olaf Hergesell, K. Tabei, Osamu Hotta, Norio Sunagawa, Ioannis Tzanakis, Emanuela Rizzioli, Mingcai Qiu, Paul F. Laflam, Gian Marco Ghiggeri, Yasufumi Kyuden, D. Ljubanovic, M.J. Nubé, W.E.M. Schouten, Carla Carasi, Joachim Lundahl, Mariko Miyazaki, Isao Ishikawa, Yasuhiko Ueda, Kazuhiko Funabiki, Michael Nomikos, Tatsuo Kobayashi, Maria Magalhães, Manabu Asano, Takayuki Fujita, Shaul M. Shasha, Revital Shurtz-Swirski, Susana Sampaio, H. Furuya, Kefaia El-Sayed Mohamed, Mitsuhiro Satoh, A. Bihorac, Ç. Özener, Renza Cristofani, Ikue Mori-Kudo, U. Assogba, Satoshi Ogata, A.J. van Houte, Shifra Sela, Hidetake Kurihara, Maria Rita Metelli, Kayoko Nomura, Giovanni Montini, Atsushi Satomura, S. Krizanac, Rodo O. von Vigier, Morito Endo, Jürgen Floege, Lara Alonso da Silva, Yasuharu Nomura, Satoko Honda, Manuel Pestana, Hassan Abd-El-Hady Ahmed, Omar da Rosa Santos, P. Cacoub, Toshihiro Shinosaki, Ikuko Miyai, Y. Asano, Yoshiharu Nishitani, Yoshio Taguma, Chien-Liang Chen, Chizuru Ishiguro, P. Xavier, Gianluca Caridi, Marina Martic, Jean-Pierre Guignard, Maura Zanolari Calderari, Akira Saito, Hua-Chang Fang, F. A. W. Kemperman, Huiqi Qu, Atsushi Yamauchi, Hisaya Tada, Gavin J. Becker, Koji Harada, Mohamed Abel-Kader Sobh, Galal Mohamed Amer, Luisa Murer, P A Conz, Hiroyuki Ohi, Ali Moshfegh, Armando A. Mendes, Osama Gheith, Daisuke Suzuki, Fatma Elhusseini, Ciro Tetta, Eugênio Pacelle Queiroz Madeira, Yoshinobu Fuke, Takashi Uzu, Kang-Ju Chou, Savvas Kazoulis, Manuel Palacín, Ioannis Christoulakis, P. Hausfater, G. Kantarcı, Hideyuki Kurioka, Ivano Moschèn, Stefan H. Jacobson, Graziella Zacchello, Satoshi Horikoshi, Atsushi Tsuchida, Ryoko Shimizu-Hirota, Petros Hatzilias, Alberto Bettinelli, Tim D. Hewitson, Raymond T. Krediet, J.C. Piette, Jacek Borawski, S. Tokay, Takafumi Ito, Mutsuo Taiji, Ronit Geron, Makoto Watanabe, M. Schoorl, Carlo Catalano, Pia Thylén, Péter Tóth-Heyn, Ching-Bun Chen, Rajiv Kumar, Shigemi Chiba, Stefan Bröer, Takao Saruta, Mahmoud El-Baz, Yuji Fujita, E. Akoğlu, Roberto Palla, Michał Myśliwiec, Toshiki Inokuchi, Yasuhiko Tomino, Yasuhiro Akai, E. Kusano, Yukiteru Asakimori, Maria Norpoth, Shih-Yuan Hung, Yee-Hsuan Chiou, Kristen J. Kelynack, Hideo Shiiki, Alberto A.E. Bertelli, Mari Kuroda, Yoshihiko Taniguchi, Kazumasa Hamano, Massimiliano Migliori, Steven McTaggart, P. Lebon, Toshio Miyata, Vincenzo Panichi, Gunilla Halldén, Soichi Haraguchi, Mario G. Bianchetti, Po-Tsang Lee, M.P.C. Grooteman, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Yutaka Yaguchi, Florian Lang, Anna Maria Bianchi, Birgit Kallinowski, Mitchell L. Halperin, M. Inoue, Mizuo Mifune, Masayuki Iwano, Masafumi Yamato, Stefano De Pietro, Hiroshi Noguchi, Koji Kuboki, Hsiao-Min Chung, Hideto Sakai, Tomokazu Nagano, Iwan Setiawan, Surinder Cheema-Dhadli, Nobuoki Kohno, Shan Lin, M. Vrkljan, Isao Shirato, Noriaki Yorioka, Adriana MacIntyre Innocenzi, Marcella Normanno, José Gerardo Oliveira, Matsuhiko Hayashi, Y. Ando, Lambertus Arisz, Krystyna Pawlak, Galina Shapiro, Ikuo Horigome, Takashi Furuta, Y. Akai, Batya Kristal, João Ramos, Mahmoud Wageh Rasem, Alexandra Albers, Sarantos Xirakis, Sérgio Fernando Ferreira Santos, Takao Kawamura, Martin Zeier, Hiroo Noshiro, Manuela Della Vella, Daniele Taccola, Isao Ohsawa, K. Galesic, Mie Ko, Sana Sayed Gazarin, Eduardo H. Garin, Guilherme Santoro-Lopes, Mutsuko Hidaka, Luca Giovannini, and Giulietta Sbragia

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
2002

5. Contents Vol. 91, 2002

Author

Steven McTaggart, Hisaya Tada, D. Ljubanovic, Gunilla Halldén, M.J. Nubé, Marina Martic, Yasufumi Kyuden, Luisa Murer, Vincenzo Panichi, W.E.M. Schouten, Eugênio Pacelle Queiroz Madeira, Mariko Miyazaki, Yasuhiko Ueda, Hidetake Kurihara, Maria Norpoth, Guilherme Santoro-Lopes, Mutsuko Hidaka, Galal Mohamed Amer, Ali Moshfegh, Carlo Catalano, Chien-Liang Chen, Stefano De Pietro, Koji Kuboki, Ryoko Shimizu-Hirota, P. Hausfater, Susana Sampaio, Yoshinobu Fuke, Manuel Palacín, Luca Giovannini, Savvas Kazoulis, Satoshi Ogata, A.J. van Houte, Ikuo Horigome, Graziella Zacchello, Alberto Bettinelli, Batya Kristal, Tim D. Hewitson, Isao Shirato, Noriaki Yorioka, Makoto Watanabe, Renza Cristofani, Sérgio Fernando Ferreira Santos, Takao Kawamura, Y. Akai, S. Krizanac, Jacek Borawski, Maura Zanolari Calderari, Nobuoki Kohno, Marcella Normanno, Giulietta Sbragia, Iwan Setiawan, U. Assogba, Mitsuhiro Satoh, Mutsuo Taiji, Y. Asano, Mahmoud El-Baz, Daisuke Suzuki, Gavin J. Becker, Akira Saito, Giovanni Montini, Stefan Bröer, Yuji Fujita, Revital Shurtz-Swirski, Paul F. Laflam, P A Conz, Ching-Bun Chen, Ioannis Christoulakis, Toshihiro Shinosaki, Takafumi Ito, Takashi Uzu, Yasuhiro Akai, Kang-Ju Chou, G. Kantarcı, Shan Lin, Atsushi Tsuchida, Hideo Shiiki, Mari Kuroda, Atsushi Satomura, Huiqi Qu, Soichi Haraguchi, Michał Myśliwiec, Masayuki Iwano, Masafumi Yamato, M. Vrkljan, Petros Hatzilias, Yoshihiko Taniguchi, Atsushi Yamauchi, Emanuela Rizzioli, Mingcai Qiu, Mohamed Abel-Kader Sobh, Sana Sayed Gazarin, Shigemi Chiba, M. Schoorl, E. Kusano, Yukiteru Asakimori, Anna Maria Bianchi, Birgit Kallinowski, Mario G. Bianchetti, Armando A. Mendes, Yutaka Yaguchi, Isao Ishikawa, Manuel Pestana, Pia Thylén, M. Inoue, Shifra Sela, Po-Tsang Lee, Massimiliano Migliori, Jean-Pierre Guignard, Olaf Hergesell, P. Lebon, Hideto Sakai, Yee-Hsuan Chiou, Kristen J. Kelynack, Alberto A.E. Bertelli, Osamu Hotta, Shaul M. Shasha, Tomokazu Nagano, Lambertus Arisz, Martin Zeier, H. Furuya, Kefaia El-Sayed Mohamed, A. Bihorac, Ç. Özener, Lara Alonso da Silva, Hiroshi Noguchi, Toshio Miyata, Takao Saruta, E. Akoğlu, Stefan H. Jacobson, Krystyna Pawlak, Ivano Moschèn, Maria Rita Metelli, Hsiao-Min Chung, Takashi Furuta, Adriana MacIntyre Innocenzi, Yoshiharu Nishitani, Kazumasa Hamano, Manabu Asano, Mizuo Mifune, Kayoko Nomura, Tatsuo Kobayashi, Gian Marco Ghiggeri, João Ramos, Mahmoud Wageh Rasem, José Gerardo Oliveira, Hassan Abd-El-Hady Ahmed, Hiroyuki Ohi, S. Tokay, Matsuhiko Hayashi, Osama Gheith, Carla Carasi, P. Xavier, Ikue Mori-Kudo, Hiroo Noshiro, Kazuhiko Funabiki, Michael Nomikos, Chizuru Ishiguro, Ikuko Miyai, Maria Magalhães, Péter Tóth-Heyn, Satoko Honda, Manuela Della Vella, Daniele Taccola, Gianluca Caridi, Yasuharu Nomura, Hideyuki Kurioka, Joachim Lundahl, P. Cacoub, Y. Ando, Ronit Geron, Toshiki Inokuchi, Eduardo H. Garin, Galina Shapiro, Roberto Palla, Shih-Yuan Hung, Yasuhiko Tomino, Ciro Tetta, Surinder Cheema-Dhadli, Alexandra Albers, Sarantos Xirakis, Florian Lang, Mitchell L. Halperin, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Jürgen Floege, Yoshio Taguma, Koji Harada, Hua-Chang Fang, F. A. W. Kemperman, Satoshi Horikoshi, Rodo O. von Vigier, Morito Endo, Omar da Rosa Santos, Norio Sunagawa, M.P.C. Grooteman, Fatma Elhusseini, Takayuki Fujita, Raymond T. Krediet, J.C. Piette, Rajiv Kumar, Hiroyuki Sasamura, K. Tabei, Ioannis Tzanakis, K. Galesic, Mie Ko, and Isao Ohsawa

Subjects
Traditional medicine, business.industry, Medicine, business
Published
2002

6. Subject Index Vol. 92, 2002

Author

Satoru Kawaguchi, Takanobu Sakemi, Ken Farrington, Itsuro Kazama, Yukihiko Kawasaki, Hidehiro Kakizaki, Masao Kanauchi, Toshihiko Hata, Y. Oyama, Sang Koo Lee, Mitsunobu Matsubara, Hiroshi Shiraga, T. Rengarajan, Patrizia Colombo, Kenji Maeda, Takao Saruta, Masaaki Inaba, Eiji Kusano, Oliviero Filiberti, Erzsébet Ladányi, Shigehisa Aoki, Sumiko Homma, Sadayoshi Ito, Abdülgaffar Vural, Hitoshi Suzuki, Hyung Wook Kim, Yasuhiro Akai, F. Corica, Takahiko Ono, Koji Harada, Giovanna Piccini, Yoshiyuki Tomiyoshi, Gilbert Deray, Sun Woo Lim, Sándor Sipka, Sigeyuki Takeda, Masayuki Iwano, Takeshi Kanda, Aquiles Jara, Júlia Széll, Arnold J. Felsenfeld, Cecilia Chacón, Zeki Odabaşi, Yoko Fujino, Yasuro Kumeda, Nora Klenk, Chin-Huang Chen, Lesley C Dinwiddie, Qiu Mingcai, Satish M. Rao, Iván Palomo, Hitoshi Goto, Choung Soo Kim, Akane Kurisu, Pasqualina Cecere, Eiji Ishimura, Hirofumi Anai, Bertalan Fodor, Jorge Isaac, Yong Soo Kim, Paik-Seong Lim, Gisho Honda, Tatsuya Nakatani, Toru Shinzato, Antonio Nicoletti, M. Imai, Masuhisa Nakamura, Mükerrem Safali, Byung Kee Bang, Fuad S. Shihab, U. Eismann, Michiko Suzuki, Yuujiro Watanabe, Toshikatsu Shimizu, Luigia Costantini, Lin Shan, Deniz Ayli, M. Buemi, Shigeo Suzuki, J. Vila Cots, Gabriella Lakos, Vincent Launay-Vacher, Carla Peona, Akira Owada, Aranka Koós, Yoshihiko Saito, Yasuhide Nakashima, Jin Kim, Huaji Chen, Akihiko Osajima, Petra Marchand, Mari Michimata, Masako Iwamoto, Yee-Yung Ng, Toshio Hashimoto, J. Gerth, G. Anastasi, Chui-Mei Tiu, R. Ravichandran, G. Cutroneo, J.A. Camacho Diaz, Magdolna Aleksza, Song Lin, Susan L. Hogan, A O Phillips, Kayser Caglar, Eri Muso, Shin Suda, Koichiro Homma, Y. Watanabe, Wu-Chang Yang, Katsuya Nonomura, Attila Nagy, Cheri V. Barrett, Sacit Turanli, Susumu Makino, Norio Kurumatani, Yoshiki Nishizawa, Yutaka Imai, Seung Hun Lee, Ning Liu, Takahiko Nagahama, Ulf Janssen, F. Floccari, Lee-Moi Thien, Nai-Phon Wang, Jürgen Floege, Chiew H. Kong, G. Stein, A. Romeo, Xixin Wu, Ryuichiro Konda, Izzet Yavuz, Soon Bae Kim, Müjdat Yenicesu, Masahiro Okazaki, Y. Asano, Su-Kil Park, C. Aloisi, Takayuki Ota, Mayumi Nagata, Giuseppe Rizzuto, Wan Young Kim, Masamiki Miwa, Yuri Ozawa, Mária Takács, Chang-Linct Yang, A. Ruello, Kaori Kanegae, Yasuo Imanishi, Marcela Vasquez, Kyoko Kitauchi, A. Sturiale, Motoaki Miyazono, Toshiaki Makino, Gloria A. Preston, David A. Alcorta, Yasushi Asano, Hideo Nakai, Kosei Segawa, Yutaro Hayashi, A. Vila Santandreu, A. Gimenez Llort, Laurence Fardet, G. Di Pasquale, Yoshiyuki Matsuo, Takeshi Suda, Naoko Matsumoto, Masahito Tamura, Jung Sik Park, K. Tamba, Koichi Hayashi, E. Kusano, Omac Tufekcioglu, Chun-Cheng Hou, Toshihiko Miwa, J. Charles Jennette, Cüneyt Ensari, Yasuhiro Komatsu, Shoji Nogae, Won Seok Yang, Ju Young Jung, A. Favaloro, Jung Ho Cha, Enikő Sárváry, Ottó Árkossy, Ronald J. Falk, C. Ito, Junzo Suzuki, Marcelo Alarcón, Can Li, O. Iimura, Motoshi Hattori, Keiji Fujiwara, Chul Woo Yang, Silvia Pierangeli, Jaime Pereira, Tsutomu Araki, Shigeru Nakai, L. Garcia Garcia, Heinfried H. Radeke, An S. De Vriese, M. Sommer, Michele Buemi, Katsumi Ito, Massimino Senatore, Narutoshi Kabashima, Bum Soon Choi, Tülin Gümüş, Yi-Hong Chou, Ruriko Nozawa, N. Frisina, Wei-Ming Hsu, Magali Ciroldi, Hirofumi Matuoka, Tadao Oohara, Shozo Hosokawa, A. Concheiro Guisan, Seval Izdes, M. Suzuki, Eveline Sowa, Hassane Izzedine, Tsen-Tsai Chen, Tomoko Nakamura, and Tsung-Hsiu Wang

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
2002

7. Measurement of Plasma and Urinary Adrenomedullin in Patients with IgA Nephropathy

Author

Yasuhiro Akai, Toshihiko Nishino, Masayuki Iwano, Atsushi Kubo, Eiji Hirata, Hiroaki Sato, Kazuhiro Dohi, Hideo Shiiki, Kenji Kangawa, Kazuo Kitamura, Hisayuki Matsuo, and Naoto Minamino

Subjects
Adult, medicine.medical_specialty, Urinary system, Radioimmunoassay, Urology, Nerve Tissue Proteins, Urine, Blood Urea Nitrogen, Nephropathy, Adrenomedullin, chemistry.chemical_compound, Internal medicine, Natriuretic Peptide, Brain, medicine, Humans, Blood urea nitrogen, Aged, Creatinine, business.industry, Glomerulonephritis, IGA, Glomerulonephritis, Middle Aged, medicine.disease, Endocrinology, chemistry, Peptides, business, Atrial Natriuretic Factor, hormones, hormone substitutes, and hormone antagonists, Kidney disease
Abstract

In this study, we measured plasma and urinary adrenomedullin (AM) concentrations in 47 patients with IgA nephropathy. Controls were 39 healthy volunteers. Plasma and urinary AM values were measured by specific radioimmunoassay. The plasma AM concentrations were higher, and the urinary AM levels were lower in patients with IgA nephropathy than in healthy volunteers. Plasma AM concentrations showed a positive correlation with serum creatinine and blood urea nitrogen, whereas urinary AM levels correlated negatively with serum creatinine and blood urea nitrogen. The plasma AM concentrations showed a positive correlation with fractional excretions of sodium and potassium. Renal biopsy specimens of patients without renal failure were scored for activity (percentage of glomeruli demonstrating cellular crescent formation, degree of mesangial proliferation and interstitial infiltration; total score = 9). Urinary AM levels were shown to be lower in the group with a high activity (score 3–9) as compared with the group with a low activity (score 0–2) based on renal biopsy. Thus, urinary levels of AM are affected by the degree of the activity in IgA nephropathy, and AM may participate in the pathophysiology of IgA nephropathy.

Published
1998

8. Association of Interleukin-1 Receptor Antagonist Gene Polymorphism with IgA Nephropathy

Author

Yoshiharu Nishitani, Kazumasa Hamano, Hideyuki Kurioka, Yasuhiro Akai, Makoto Watanabe, Masayuki Iwano, Hideo Shiiki, and Koji Harada

Subjects
Biopsy, Sialoglycoproteins, urologic and male genital diseases, Nephropathy, Pathogenesis, Gene Frequency, medicine, Humans, Allele frequency, Alleles, DNA Primers, Polymorphism, Genetic, Proteinuria, Base Sequence, business.industry, Case-control study, Interleukin, Glomerulonephritis, IGA, medicine.disease, Glomerular Mesangium, Interleukin 1 Receptor Antagonist Protein, Variable number tandem repeat, Case-Control Studies, Immunology, Gene polymorphism, medicine.symptom, business, Cell Division
Abstract

It is evident that cytokines play an important role in the pathogenesis as well as disease progression of IgA nephropathy (IgAN). Several gene polymorphisms of the pertinent cytokines have an influence on the level of cytokine production. Interleukin-1 receptor antagonist (IL-1ra) gene polymorphism has been found to affect disease susceptibility and activity in several inflammatory diseases. In the present study, we analyzed polymorphism of the variable number tandem repeat (VNTR) of IL-1ra in patients diagnosed as having IgAN (n = 106) and normal controls (n = 74). The allele frequency of IL-1ra polymorphism in IgAN patients was not statistically different from that of the control group. There was no significant difference in the carriage rate of the two-repeat allele (IL1RN*2) between IgAN patients and the control group (8.5 vs. 6.8%). The carriage rate of IL1RN*2 was significantly higher in IgAN patients with severe proteinuria (≧1.6 g/day) or increased serum creatinine level (≧2.0 mg/dl; p < 0.05). Furthermore, the carriage rate of IL1RN*2 was significantly higher in patients with severe mesangial cell proliferation (p < 0.01). Our results suggest that IL-1ra polymorphisms are not associated with the development of IgAN in Japanese patients but the presence of IL1RN*2 may be associated with increased disease activity.

Published
2002

9. Validation of Simple Indices to Assess Insulin Sensitivity and Pancreatic Beta-Cell Function in Patients with Renal Dysfunction

Author

Yasuhiro Akai, Toshio Hashimoto, and Masao Kanauchi

Subjects
Blood Glucose, Male, medicine.medical_specialty, medicine.medical_treatment, Renal function, Gastroenterology, Nephropathy, Islets of Langerhans, Insulin resistance, Internal medicine, Diabetes mellitus, medicine, Hyperinsulinemia, Humans, Aged, Glucose tolerance test, medicine.diagnostic_test, business.industry, Insulin, Reproducibility of Results, Glucose Tolerance Test, Middle Aged, medicine.disease, Endocrinology, Kidney Failure, Chronic, Female, Insulin Resistance, business, Kidney disease
Abstract

Background/Aims: Insulin resistance and hyperinsulinemia has been reported in patients with chronic renal failure. However, usefulness and validation of new indices for assessment to insulin sensitivity and pancreatic beta-cell function were unknown. Methods: We evaluated insulin sensitivity and pancreatic beta-cell function in 61 normal glucose tolerant (NGT) and 60 diabetic (DM) subjects; both groups were subdivided as normal renal function (NRF; Ccr ≥ 70 ml/min) and impaired renal function (IRF; Ccr 0–180). Results: There was no evidence of insulin resistance in NGT-IRF group. No differences in both insulinogenic index and first-phase insulin secretion index between NGT-NRF and NGT-IRF, but these were significantly decreased in DM-NRF and DM-IRF. There were inverse linear correlations between the insulin sensitivity index and insulin-AUC0–180 in patients with NGT and DM, respectively. These correlations were similarly robust in NRF subjects and IRF subjects. Conclusions: New indices for assessment of insulin sensitivity and pancreatic beta-cell function calculated from plasma glucose and plasma insulin concentrations after OGTT are applicable for clinical use even in patients with renal dysfunction.

Published
2002

10. Front & Back Matter

Author

George A. Kaysen, Lorien S. Dalrymple, Satoshi Okayama, Jasmin Divers, Lise Bankir, Xin Zou, Giulio Genovese, Dong Chan Jin, Gilberto Velho, Euy Jin Choi, Eun Sil Koh, Yon Su Kim, Quan Hong, Lingyi Lu, Martin B A Heemskerk, Robert Nee, Katsuhiko Morimoto, Cynthia Delgado, Louis Potier, Kamel Mohammedi, Paul Muntner, Merel van Diepen, Lyndsay S. Baines, David J. Friedman, Dustin J. Little, Piet M. ter Wee, Shin Wook Kang, Elvira O. Gosmanova, Menso J. Nubé, Ho Chul Song, Barry I. Freedman, Otto Kamp, Kenji Onoue, Christina W. Chen, Mary Cushman, Romy Hansildaar, Kamyar Kalantar-Zadeh, Yasuhiro Akai, Rebecca Scherzer, Ahmed Alrifai, Yoshihiko Saito, Nadia Matallah, Camiel L.M. de Roij van Zuijdewijn, Xiu-Juan Liu, Michiel L. Bots, Michael G. Shlipak, Carmen A. Peralta, Rahul M. Jindal, S. Ananth Karumanchi, Frédéric Fumeron, Kyungsoo Lee, Rika Kawakami, Carl D. Langefeld, Chul Woo Yang, Kirsten L. Johansen, Masaru Matsui, Aline C. Hemke, Satria Sajuthi, David R. McWilliams, Yan-Yan Yu, Jeff W. Chou, Miho Tagawa, Michel Marre, Stephanie Shieh, Nam Ho Kim, Yong Kyun Kim, Yukiji Takeda, Ken-ichi Samejima, Beverley Balkau, Gregory A. Hawkins, Hiroyuki Kawata, Ronan Roussel, Su Hyun Kim, Yong Lim Kim, Friedo W. Dekker, Martin R. Pollack, Keisuke Okamoto, Glenn M. Chertow, Ray El Boustany, Man Li, Kaoru Tanabe, Jun L. Lu, Elani Streja, Barbara Grimes, Csaba P. Kovesdy, Lijun Ma, Zhen Wang, Pamela J. Hicks, Li-Hong Xu, John Kornak, Druckerei Stückle, Suzanne E. Judd, Rulan S. Parekh, William C. Cushman, Miklos Z. Molnar, Peter J. Blankestijn, Young Ok Kim, Nadine Bouby, Donald W. Bowden, Muriel P.C. Grooteman, Marinus A. van den Dorpel, and Andries J. Hoitsma

Subjects
Optics, Reproductive Medicine, Nephrology, business.industry, Medicine, Obstetrics and Gynecology, business, Geology, Front (military)
Published
2012

11. Acknowledgement to the Reviewers

Author

Yasuro Kumeda, Nora Klenk, Itsuro Kazama, Shin Suda, Ryuichiro Konda, Soon Bae Kim, Satish M. Rao, Iván Palomo, Toru Shinzato, Ken Farrington, Masayuki Iwano, Yukihiko Kawasaki, A. Sturiale, Ronald J. Falk, Yoshiyuki Tomiyoshi, Gilbert Deray, U. Eismann, Masaaki Inaba, Silvia Pierangeli, Marcela Vasquez, L. Garcia Garcia, Yasuhide Nakashima, Hitoshi Suzuki, Aquiles Jara, Júlia Széll, G. Di Pasquale, Takeshi Suda, Jaime Pereira, Lin Shan, Deniz Ayli, M. Buemi, Yee-Yung Ng, Masahito Tamura, Akane Kurisu, Satoru Kawaguchi, Takanobu Sakemi, Hidehiro Kakizaki, Masao Kanauchi, Y. Oyama, J. Vila Cots, A. Favaloro, Ulf Janssen, Kosei Segawa, Yoshiyuki Matsuo, Mükerrem Safali, Susumu Makino, Massimino Senatore, Tülin Gümüş, Yi-Hong Chou, Yong Soo Kim, G. Stein, J.A. Camacho Diaz, Magdolna Aleksza, A. Romeo, Masako Iwamoto, Ruriko Nozawa, Akihiko Osajima, Y. Asano, Keiji Fujiwara, G. Cutroneo, T. Rengarajan, Patrizia Colombo, Su-Kil Park, Hiroshi Shiraga, Oliviero Filiberti, Eri Muso, Koichiro Homma, Jürgen Floege, Sigeyuki Takeda, Takahiko Ono, Arnold J. Felsenfeld, Takayuki Ota, A. Vila Santandreu, N. Frisina, Wei-Ming Hsu, Magali Ciroldi, Choung Soo Kim, Bertalan Fodor, Mari Michimata, Lee-Moi Thien, Nai-Phon Wang, Masahiro Okazaki, Yuri Ozawa, Petra Marchand, J. Charles Jennette, Motoshi Hattori, Xixin Wu, Chin-Huang Chen, Izzet Yavuz, Pasqualina Cecere, A. Ruello, Omac Tufekcioglu, Heinfried H. Radeke, Cheri V. Barrett, Kyoko Kitauchi, Jin Kim, Zeki Odabaşi, Yoko Fujino, Hitoshi Goto, Huaji Chen, Hideo Nakai, M. Imai, An S. De Vriese, Hirofumi Matuoka, Seung Hun Lee, Ning Liu, Attila Nagy, Yoshiki Nishizawa, Carla Peona, Akira Owada, Aranka Koós, Katsumi Ito, Tadao Oohara, Shozo Hosokawa, M. Suzuki, Bum Soon Choi, Aled O. Phillips, Yasuhiro Komatsu, Kayser Caglar, M. Sommer, Sun Woo Lim, Michele Buemi, Tsung-Hsiu Wang, Giovanna Piccini, Toshihiko Hata, Luigia Costantini, Tomoko Nakamura, Y. Watanabe, Wu-Chang Yang, Katsuya Nonomura, Masuhisa Nakamura, Narutoshi Kabashima, Kenji Maeda, J. Gerth, Toshihiko Miwa, Sang Koo Lee, Eveline Sowa, Masamiki Miwa, G. Anastasi, Mitsunobu Matsubara, Takao Saruta, A. Concheiro Guisan, Seval Izdes, Susan L. Hogan, Shigehisa Aoki, Antonio Nicoletti, Lesley C Dinwiddie, Fuad S. Shihab, Paik-Seong Lim, Eiji Kusano, Gisho Honda, Takahiko Nagahama, Yuujiro Watanabe, Yutaka Imai, Enikő Sárváry, Yasushi Asano, Eiji Ishimura, Yoshihiko Saito, Mayumi Nagata, Takeshi Kanda, Toshio Hashimoto, F. Floccari, Qiu Mingcai, Naoko Matsumoto, Michiko Suzuki, C. Aloisi, Wan Young Kim, Chui-Mei Tiu, Cecilia Chacón, David A. Alcorta, Jung Sik Park, Hassane Izzedine, Mária Takács, Tsen-Tsai Chen, Byung Kee Bang, Koichi Hayashi, Junzo Suzuki, Motoaki Miyazono, A. Gimenez Llort, Giuseppe Rizzuto, Kaori Kanegae, Yasuo Imanishi, Norio Kurumatani, Toshiaki Makino, Chang-Linct Yang, Yutaro Hayashi, Jung Ho Cha, Song Lin, Chul Woo Yang, Won Seok Yang, Marcelo Alarcón, Müjdat Yenicesu, Tsutomu Araki, Gloria A. Preston, O. Iimura, Jorge Isaac, Toshikatsu Shimizu, C. Ito, Can Li, Hirofumi Anai, Tatsuya Nakatani, Shigeo Suzuki, Gabriella Lakos, Cüneyt Ensari, Shoji Nogae, Ottó Árkossy, Vincent Launay-Vacher, R. Ravichandran, K. Tamba, E. Kusano, Shigeru Nakai, Sacit Turanli, Chun-Cheng Hou, Ju Young Jung, Chiew H. Kong, Erzsébet Ladányi, Hyung Wook Kim, Yasuhiro Akai, F. Corica, Koji Harada, Sumiko Homma, Laurence Fardet, Sadayoshi Ito, Abdülgaffar Vural, and Sándor Sipka

Subjects
Medical education, business.industry, Acknowledgement, Medicine, business
Published
1998

12. Editorial / Publisher’s Note

Author

Marcela Vasquez, G. Di Pasquale, Takeshi Suda, Mükerrem Safali, Akihiko Osajima, Petra Marchand, Itsuro Kazama, Sacit Turanli, Hirofumi Matuoka, Chang-Linct Yang, Luigia Costantini, F. Floccari, Tadao Oohara, Shozo Hosokawa, Chiew H. Kong, Yutaro Hayashi, Heinfried H. Radeke, An S. De Vriese, J. Gerth, G. Anastasi, Takahiko Ono, Shigehisa Aoki, Satoru Kawaguchi, Takanobu Sakemi, Sumiko Homma, Sadayoshi Ito, Toshihiko Hata, Katsumi Ito, Mária Takács, Kenji Maeda, Takahiko Nagahama, Kyoko Kitauchi, O. Iimura, Arnold J. Felsenfeld, Jorge Isaac, Masayuki Iwano, Yasuhide Nakashima, Bum Soon Choi, Hidehiro Kakizaki, Masao Kanauchi, Yoshihiko Saito, Masako Iwamoto, G. Cutroneo, Y. Oyama, Qiu Mingcai, Ken Farrington, Toshikatsu Shimizu, Cheri V. Barrett, Fuad S. Shihab, A. Concheiro Guisan, M. Imai, Abdülgaffar Vural, Antonio Nicoletti, Seval Izdes, Masahito Tamura, K. Tamba, Massimino Senatore, Masaaki Inaba, Erzsébet Ladányi, Lesley C Dinwiddie, Yong Soo Kim, Tülin Gümüş, E. Kusano, Toshio Hashimoto, Hyung Wook Kim, Eiji Ishimura, Shin Suda, Tatsuya Nakatani, Yi-Hong Chou, Susan L. Hogan, Jung Ho Cha, Ruriko Nozawa, Marcelo Alarcón, J.A. Camacho Diaz, Magdolna Aleksza, A. Favaloro, Yutaka Imai, Yasuhiro Akai, F. Corica, Yuujiro Watanabe, Chun-Cheng Hou, Shigeo Suzuki, Aquiles Jara, Gabriella Lakos, N. Frisina, Júlia Széll, Ju Young Jung, Wei-Ming Hsu, C. Aloisi, Keiji Fujiwara, Motoshi Hattori, Akane Kurisu, Tsutomu Araki, Yoshiyuki Tomiyoshi, Gilbert Deray, Wan Young Kim, Carla Peona, Akira Owada, Aranka Koós, Magali Ciroldi, Ronald J. Falk, Chul Woo Yang, Chui-Mei Tiu, Kayser Caglar, Koji Harada, Jaime Pereira, Song Lin, Tsung-Hsiu Wang, Katsuya Nonomura, Mari Michimata, Yasushi Asano, Masamiki Miwa, Giuseppe Rizzuto, Naoko Matsumoto, Norio Kurumatani, Seung Hun Lee, Ning Liu, Kaori Kanegae, Jin Kim, Yasuro Kumeda, Huaji Chen, Yasuo Imanishi, Jung Sik Park, Nora Klenk, M. Sommer, A O Phillips, Sang Koo Lee, J. Charles Jennette, Hideo Nakai, Hirofumi Anai, Michele Buemi, Cüneyt Ensari, Attila Nagy, Yoshiki Nishizawa, Toshiaki Makino, Shoji Nogae, Won Seok Yang, Mitsunobu Matsubara, Takao Saruta, Narutoshi Kabashima, Eiji Kusano, Yasuhiro Komatsu, Shigeru Nakai, Ottó Árkossy, Sun Woo Lim, Ryuichiro Konda, Chin-Huang Chen, Soon Bae Kim, Hitoshi Goto, Yukihiko Kawasaki, Takeshi Kanda, Cecilia Chacón, L. Garcia Garcia, J. Vila Cots, Kosei Segawa, T. Rengarajan, Patrizia Colombo, Vincent Launay-Vacher, Yoshiyuki Matsuo, R. Ravichandran, Hitoshi Suzuki, C. Ito, Tomoko Nakamura, Can Li, Y. Watanabe, Wu-Chang Yang, Hassane Izzedine, Tsen-Tsai Chen, Zeki Odabaşi, Yoko Fujino, Eri Muso, Koichiro Homma, M. Suzuki, Jürgen Floege, Paik-Seong Lim, Gisho Honda, Susumu Makino, Xixin Wu, Müjdat Yenicesu, Eveline Sowa, A. Sturiale, Giovanna Piccini, Y. Asano, Gloria A. Preston, A. Romeo, Su-Kil Park, Izzet Yavuz, Masuhisa Nakamura, Mayumi Nagata, Motoaki Miyazono, A. Gimenez Llort, Laurence Fardet, Choung Soo Kim, Bertalan Fodor, David A. Alcorta, Junzo Suzuki, Toshihiko Miwa, Lee-Moi Thien, Nai-Phon Wang, Masahiro Okazaki, Yuri Ozawa, Koichi Hayashi, Enikő Sárváry, A. Ruello, Byung Kee Bang, Sándor Sipka, Satish M. Rao, Iván Palomo, Silvia Pierangeli, Toru Shinzato, U. Eismann, Michiko Suzuki, Hiroshi Shiraga, Oliviero Filiberti, Sigeyuki Takeda, Ulf Janssen, Pasqualina Cecere, Takayuki Ota, Lin Shan, Deniz Ayli, M. Buemi, Yee-Yung Ng, A. Vila Santandreu, G. Stein, and Omac Tufekcioglu

Subjects
business.industry, Medicine, business, Classics
Published
2002

13. Consultants for the American Journal aof Nephrology 1998

Author

Jesus Calviño, Matthew J. Arduino, Gianna Mastroianni Kirsztajn, Yoshiki Sekijima, Christian Mrowka, Shigeru Nakano, J Baltar, Atsushi Horiuchi, Masao Kanauchi, Kendo Kiyosawa, Toshio Kakihara, Kozo Hishimoto, Hirofumi Hasegawa, M. Lucia Ferraz, Daniel Novoa, Elena Pintos, Michael H. Schwenk, Bernhard Heintz, Mark E. Williams, Zora Krivosiková, Toshikazu Kigoshi, Dolores Güimil, Kamlesh Patel, Eduardo Silva, Monique Delorme, Takashi Ohno, Heinz-Günter Sieberth, Edward Kessler, Takafumi Matsumoto, Edmundo P.A. Lopes, Masayuki Iwano, Koji Suzuki, Ling-Yoeu Yang, Wei-Perng Chen, Jürgen Reul, Victor Arcocha, Javier Mardaras, Ann Chen, Ching-Yuang Lin, Chaim Charytan, J Alvarez-Grande, Bahar Bastani, Wolfgang Fierlbeck, August Heidland, Toshihiro Takao, Y.F. Wang, Michele H. Mokrzycki, Elise M. Jochimsen, David Galli, Kazuhiro Dohi, Thomas R. Welch, Johanne Ismaïl, Tohru Umekawa, Satoru Yonekawa, Katarína Šebeková, Toru Yamaguchi, William R. Jarvis, Yuichi Kobayashi, Alexander S. Goldfarb-Rumyantzev, Anne M. Torres, Aparecido B. Pereira, Atsushi Tanaka, Ricardo Sesso, Manabu Takei, Jose A. Diaz-Buxo, Hiroshi Hayakawa, Ahmed Shafik, Shu-ichi Ikeda, Hiroaki Sato, Makoto Uchiyama, Leonard P. Caccamo, Tung-Po Huang, Shuichi Yamaura, Katsuhito Miyazawa, Atsushi Kubo, Bruce Spinowitz, Atsushi Sasaoka, Brenda P. Youngblood, Ryuzo Tsugawa, Hideyuki Kurioka, C.J. Chang, Toshio Yanagihara, Wakako Nanamiya, Lucila M.V. Lopes, Koji Nishiya, XoseM. Lens, Francisco Ortega, Chamberlain I. Obialo, Mika Sakaguchi, Hiroyuki Ito, Leszek Pączek, Teresa Cordal, Elizabeth Czyziw, Tomomasa Oguchi, Hisao Tanaka, Takashi Kurita, Loretta Carson, Than N. Oo, Charles Frenette, Michael C. Braun, Fumio Kurogouchi, T oshiya Takeda, Masanori Hara, Nathan P. Ritchey, Akio Imada, Barbara A. Erickson, Eiji Hirata, J. Dämmrich, A. Laures, Dianne Carter, Kazuhiko Hora, Junya Onozuka, Sonia M. Aguero, Eiichirou Mawatari, Ramón Peces, Jerome I. Tokars, Shiroshi Kitagawa, Mary Gellens, Rafael Romero, Kenzo Uchida, Yasuhiro Akai, Beverly Hernandez, Ichiro Iwamoto, Hiroaki Chikazawa, Kimbroe J. Carter, Rafael A. Navascués, Stephen Lapierre, Domingo Sanchez-Guisande, and Frank Castro

Subjects
Nephrology, medicine.medical_specialty, business.industry, Family medicine, Internal medicine, medicine, business
Published
1998

Catalog

Books, media, physical & digital resources
See catalog results