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A study conducted at the University of Medicine & Pharmacy Ho Chi Minh City focused on discovering small molecules that inhibit vascular endothelial growth factor receptor 2 (VEGFR-2) for potential anticancer medications. The research utilized deep-learning-based molecular models and optimization approaches to generate 493 uncharted small molecules, which were assessed for their inhibitory potential. The study concluded by shortlisting newly generated molecules with acceptable results for further investigation. For more information, readers can refer to the article "Discovery of Vascular Endothelial Growth Factor Receptor 2 Inhibitors Employing Junction Tree Variational Autoencoder With Bayesian Optimization and Gradient Ascent" published in ACS Omega. [Extracted from the article]

Researchers from International University in Ho Chi Minh City, Vietnam, have developed a gold nanoparticle-based biosensor for the detection of Lysozyme using decomposition Mueller matrix polarimetry. The study utilized DNA aptamers as recognition elements and gold nanoparticles as sensing elements, showing linear variations in optical parameters with Lysozyme concentration. The research, supported by Vietnam National University Ho Chi Minh City, offers a potential tool for the detection of Lysozyme in various diseases. The study has been peer-reviewed and published in Optics & Laser Technology. [Extracted from the article]

Researchers at Ton Duc Thang University in Ho Chi Minh City, Vietnam, have conducted a study on the application of Mesenchymal Stem Cells (MSCs) for the therapy discovery of neurodegenerative diseases. Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and ALS are characterized by progressive brain cell degeneration. The study explores the potential of MSCs in reducing symptoms and addressing the pathogenesis of these diseases through their anti-apoptotic, anti-inflammatory, and antioxidative effects. This research aims to identify more effective therapies for neurodegenerative diseases by investigating the effects and applications of MSCs. [Extracted from the article]

A recent study from International University in Ho Chi Minh City, Vietnam, explores the use of polymeric microneedle arrays for transdermal drug delivery in clinical applications. The research highlights the benefits of this technology in enhancing drug delivery by penetrating the skin painlessly and minimally invasively. The study discusses the biodegradability, biocompatibility, and low toxicity of polymeric microneedle arrays, offering insights into their potential for a wide range of clinical applications. This peer-reviewed research provides a comprehensive overview of the engineering concepts, challenges, and future perspectives of polymeric microneedle arrays in healthcare. [Extracted from the article]

A recent study conducted in Ho Chi Minh City, Vietnam, focused on the synthesis of novel triphenylpyrazoline 4-toluenesulfonylureas (PYSUs) for potential anticancer drugs and fluorescent probes to detect fluoride ions. The research found that compound 3a exhibited strong antiproliferative activity against HepG2 and MDA-MB-231 cancer cell lines, while compound 3b showed promising results as a fluorescent probe for detecting fluoride ions. The study concluded that PYSUs have the potential to serve as fluorescent sensors for fluoride ions in living cancer cells, as demonstrated through fluorescent imaging of TBAF-incubated cells. [Extracted from the article]

A study conducted by Nguyen Tat Thanh University in Ho Chi Minh City, Vietnam, introduces a new method for rapidly detecting viable Vibrio parahaemolyticus cells in seafood samples. By combining cis-diamminedichloroplatinum (CDDP) with colorimetric loop-mediated isothermal amplification (LAMP), the assay can selectively identify live cells, improving accuracy in food safety assessments. The optimized CDDP-LAMP procedure detects live V. parahaemolyticus within 1 hour, showing excellent specificity and a detection limit of 2.348 CFU per reaction. This research provides a model for screening various bacterial pathogens and enhancing foodborne illness risk assessments. [Extracted from the article]

Researchers at Nong Lam University in Ho Chi Minh City, Vietnam, have developed a novel antibacterial biofilm using bacterial cellulose from jackfruit rags, polyvinyl alcohol, silver nanoparticles, and Eclipta prostrata extract. The biofilm showed strong antibacterial properties against Escherichia coli and Staphylococcus aureus, making it a potential candidate for antibacterial food packaging. The study was supported by the Ministry of Education and Training and Nong Lam University, and the findings were published in Food Packaging and Shelf Life. [Extracted from the article]

A study conducted at Ho Chi Minh City Open University in Vietnam analyzed how firms adjust their cash conversion cycle in response to uncertainty in the banking sector. The research found that firms tend to reduce their cash cycles during periods of increased uncertainty within the banking sector. The study also highlighted that the impact of banking uncertainty on cash cycles is more pronounced in non-state-owned companies or during macroeconomic shocks like the global financial crisis and the COVID-19 pandemic. The research suggests implications for bank-based emerging countries to manage working capital more effectively in uncertain times. [Extracted from the article]

A recent study conducted at a major children's hospital in Ho Chi Minh City, Vietnam, focused on the economic burden of encephalitis in pediatric patients. The research found that the median cost of illness for children with encephalitis was estimated at US $1,859, with direct medical costs being the main cost driver. The study highlighted the importance of understanding the financial impact of pediatric encephalitis to guide policymakers in developing effective intervention strategies. [Extracted from the article]

A study conducted in Ho Chi Minh City, Vietnam, focused on the treatment of 'pink pulseless' hands in children following supracondylar humerus fractures. The research analyzed medical records of 88 pediatric patients to determine the optimal therapeutic approach, with most cases showing satisfactory outcomes after closed reduction and percutaneous pinning. The study concluded that urgent vascular exploration is generally not necessary for children with this condition, but further research is needed to address persistent pulselessness and recurrent pulse loss. The research was published in The Journal of Hand Surgery and can be accessed online for more information. [Extracted from the article]

A recent report from International University in Ho Chi Minh City, Vietnam, highlights the importance of improving employees' perceived organizational support (POS), felt obligation (FO), and transformational leadership (TL) to enhance employee retention (ER) in remote and hybrid work environments. The study, based on data from 300 remote employees in Vietnam, emphasizes the need for organizations to focus on creating supportive remote work policies to retain employees and maintain a competitive advantage, especially in the post-pandemic context. The research findings suggest that POS directly promotes ER, with an indirect influence through FO, and that transformational leadership moderates these relationships. This study contributes to the understanding of how organizations can enhance workforce competitiveness in remote work settings. [Extracted from the article]

A study conducted in Ho Chi Minh City, Vietnam, explored the efficacy of adipose-derived stem cells (ADSCs) in treating psoriasis-like inflammation in a mouse model. The research found that ADSC-treated mice showed lower severity of psoriasis-like lesions, reduced expression of key disease-associated cytokines, and improved histopathological features compared to non-treated mice. The study concluded that the treatment efficacy depended on the dose of ADSCs used, highlighting the therapeutic potential of ADSC subcutaneous injections in mitigating psoriasis-like skin lesions. [Extracted from the article]

Researchers from Ton Duc Thang University in Ho Chi Minh City, Vietnam, conducted a study on the chemical compositions, anti-inflammatory, and anti-cancer effects of leaf essential oils from three species of the Rutaceae family. The essential oils from Acronychia pedunculata and Euodia lepta showed strong inhibitory effects against cancer cells, while Severinia monophylla exhibited a lower anti-cancer effect. Euodia lepta oil demonstrated a high anti-inflammatory effect, making it a potential medicine for cancer or inflammation-associated diseases. The research has been peer-reviewed and provides valuable insights into the medicinal properties of these essential oils. [Extracted from the article]

Researchers from the University of Medicine & Pharmacy Ho Chi Minh City have developed a method for detecting impurities in sartan medicines, specifically nitrosamines and AZBT. The study utilized high-performance liquid chromatography-tandem mass spectrometry to quantify these impurities in pharmaceuticals. The research found that while eight samples contained AZBT within regulatory limits, no nitrosamine impurities were detected in any of the samples. [Extracted from the article]

A study conducted by the Ho Chi Minh City University of Education in Vietnam focused on the psychological difficulties and needs for psychological services among high school students in Thu Duc City. The research found significant differences in difficulties and the need for psychological services among students in different grades, with academic performance also playing a role. The study emphasized the importance of school counselors, educators, and teachers in evaluating students' counseling needs and providing timely support and interventions when students face challenges. [Extracted from the article]

A recent study from the University of the Sciences in Ho Chi Minh City, Vietnam, explores the use of artificial intelligence (AI) in laryngoscopy for diagnosing vocal fold disorders. The research highlights the potential of AI to improve diagnostic accuracy and efficiency in healthcare, while also emphasizing the importance of addressing ethical and legal challenges. By examining dataset collection, algorithm bias, and responsible clinical application, the study aims to promote a comprehensive understanding of AI's role in laryngoscopy, ensuring fairness, trust, and adherence to medical ethics. This research has been peer-reviewed and offers valuable insights into the intersection of technology and healthcare ethics. [Extracted from the article]

Researchers at Ton Duc Thang University in Ho Chi Minh City, Vietnam, have conducted a study on mineralized biopolymers-based scaffolds encapsulating dual drugs for alveolar ridge preservation and bone tissue engineering. The study optimized gelatin/alginate scaffolds soaked in concentrated simulated body fluid to enhance hydroxyapatite crystal formation, while also evaluating biocompatibility through various assays. The research concluded that the scaffolds showed controlled drug release, biocompatibility, and potential for promoting bone regeneration, setting the stage for future in vivo studies. This study contributes to the field of tissue engineering and offers insights into the development of innovative scaffolds for dental and bone applications. [Extracted from the article]

Researchers at Ton Duc Thang University in Ho Chi Minh City, Vietnam, have isolated aristolactam BII from the aerial parts of Houttuynia cordata Thunb. and evaluated its anti-inflammatory effects. The study found that aristolactam BII effectively reduced edema severity in mice, potentially inhibiting inflammatory proteins COX-1 and COX-2. This research provides valuable insights into the bioactivities of aristolactam BII and its potential as an anti-inflammatory agent. [Extracted from the article]

Researchers from Ton Duc Thang University in Ho Chi Minh City, Vietnam, have focused on Monkeypox, an infectious disease caused by the monkeypox virus (MPXV). They specifically studied the A42R profilin-like protein, the first available structure among MPXV proteins, to identify potential inhibitors using computational methods. Through molecular docking simulations, they found 20 tripeptides with strong binding affinity to A42R, with two tripeptides containing tryptophan showing the highest affinity. This study provides insights for developing targeted therapies against MPXV infections, emphasizing the structural advantage for potential treatments. [Extracted from the article]

Researchers from Nguyen Tat Thanh University in Ho Chi Minh City, Vietnam, conducted a computational study to explore the potential of buckyballs as inhibitors of BACE1 in Alzheimer's treatment. Through molecular docking and simulations, they identified three promising compounds that could bind to BACE1, with one showing the greatest potential. This research lays the groundwork for developing new BACE1 inhibitors using buckyball structures, offering a promising approach for Alzheimer's therapy. The study has been peer-reviewed and provides valuable insights into emerging technologies in the field of neurodegenerative diseases. [Extracted from the article]

A study conducted in Ho Chi Minh City, Vietnam, compared the effectiveness of real-time polymerase chain reaction (PCR) and culture in detecting pathogens in pediatric severe community-acquired pneumonia (sCAP). The research found that real-time PCR detected pathogens in 92.9% of patients, while culture isolated bacteria in 67.9% of patients. The study concluded that real-time PCR was more effective in detecting microorganisms and highlighted its value in identifying pathogens in children with sCAP, especially in cases involving complex pathogens or requiring timely identification. [Extracted from the article]

Researchers at Ho Chi Minh City University of Technology and Education conducted a study on the levels and health risks of disinfection by-products (DBPs) in the drinking water supply of Ho Chi Minh City, Vietnam. The study found that DBP levels were significantly higher in one zone compared to another, with trihalomethanes (THMs) being the main contributors to DBPs. The research suggested that water should be pretreated to reduce the impact of DBPs on human health. This study provides valuable insights into the potential risks associated with drinking water in Ho Chi Minh City. [Extracted from the article]

Researchers at the University of Medicine & Pharmacy Ho Chi Minh City in Vietnam have conducted a study on Coldenia procumbens L., a medicinal plant traditionally used to treat various ailments. The study explores the botany, traditional uses, phytochemical profile, and pharmacological effects of the plant, revealing its antioxidant, antimicrobial, anti-diabetic, anti-inflammatory, and other beneficial properties. The researchers suggest further investigation to harness the plant's potential for novel product development in medicine, cosmetics, and health supplements. This study provides valuable insights into the medicinal properties of Coldenia procumbens L. and its potential applications in various fields. [Extracted from the article]

Researchers at Nguyen Tat Thanh University in Ho Chi Minh City, Vietnam, have developed a novel composite material combining plate-like Cu2O and reduced graphene oxide (rGO) nanosheets to enhance bactericidal activity. The composite demonstrated superior performance in killing bacteria such as E. coli and S. aureus, attributed to its ability to generate reactive oxygen species (ROS) and mechanically disrupt bacterial cell membranes. This study highlights the potential of the copper oxide-based composite as a next-generation antibacterial material to address antimicrobial resistance, with significant implications for future research and applications in the field of nanotechnology. [Extracted from the article]

A study conducted by Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam, focused on the prevalence, antimicrobial resistance, and genomic comparison of Salmonella in pig farms in Myanmar with varying levels of intensification. The research found that intensive pig farming had a higher prevalence of multi-drug resistant isolates compared to backyard and semi-intensive farms. The study highlighted the importance of monitoring antimicrobial resistance and virulence potential of Salmonella at all scales of production to mitigate zoonotic risks. The results emphasized the complex relationship between animal production intensification and the prevalence, diversity, and antimicrobial resistance of Salmonella in pig farms. [Extracted from the article]

Researchers at International University in Ho Chi Minh City, Vietnam, conducted a study on the polarization properties of colorectal cancer using the Mueller matrix decomposition method. The study compared optical parameters of healthy and cancerous rectal tissue samples, finding significant differences in certain properties between the two tissue types. The research suggests that these parameters could potentially serve as biomarkers for the diagnosis of rectal cancer. The study has been peer-reviewed and provides valuable insights into the characterization of colorectal cancer. [Extracted from the article]

A recent study conducted at Ho Chi Minh City University of Technology and Education in Vietnam has explored the dyeability of silk fabric using anthocyanin extracted from butterfly pea flowers. The researchers found that microwave-assisted extraction was more effective than conventional methods. They examined the concentration of anthocyanin in the extracts and dyed silk samples using various analytical techniques. The study also investigated the impact of dye extract concentration, temperature, time duration, and mordants on color strength and color difference. The presence of metal salts, such as ferrous sulfate, copper sulfate, and potassium aluminum sulfate, improved the dyeability of silk fabric. The research concluded by testing the color fastness to washing on the dyed silk samples. This study provides valuable information for those interested in natural dyes and their environmental and health benefits. [Extracted from the article]

A study conducted by the University of Medicine & Pharmacy Ho Chi Minh City in Vietnam has developed a propellant-free foam formulation for the treatment of burns. The researchers aimed to create a non-propellent foamed microemulsion-based system using tamanu oil and nanocurcumin, which would be effective, safe, and fast-acting. The foam generated by the formulation showed promising results in reducing wound area in a third-degree burn mice model. The researchers believe that this propellant-free foam has potential for wound healing, particularly for burn injuries. [Extracted from the article]

A recent study conducted in Ho Chi Minh City, Vietnam, aimed to determine the self-management practices of people with epilepsy and the associated factors. The study included 147 adults with epilepsy and measured their self-management practices using the Vietnamese Epilepsy Self-Management Scale (V-ESMS). The results showed a moderate overall V-ESMS score, with higher education levels correlating with better self-management practices. The study suggests that educational interventions could significantly enhance self-management practices among people with epilepsy. This research has been peer-reviewed and provides valuable insights into epilepsy management in Vietnam. [Extracted from the article]

A recent study conducted by Van Lang University in Ho Chi Minh City, Vietnam, has explored the use of a perovskite called LaZnO3 as a photocatalyst for the degradation of the antibiotic sulfamethizole (SMZ) under visible light activation. The results showed that LaZnO3 was able to degrade SMZ by 99.2% within 4 hours, with a mineralization proportion of 58.7%. The study also identified three degradation pathways of SMZ and analyzed the toxicity of the intermediates. The researchers concluded that LaZnO3-based photocatalysis shows promise for practical antibiotic treatment. [Extracted from the article]

A study conducted by researchers at Van Lang University in Ho Chi Minh City, Vietnam, examined the aggregation behavior and physicochemical parameters of a mixture of the anionic surfactant sodium dodecyl sulfate (SDS) and the antibiotic drug ofloxacin (OFC) in different hydrotropes (HDTs) media. The study found that the micelle formation of the SDS + OFC mixture was influenced by the nature and composition of the additives as well as temperature variations. The research also evaluated the molar heat capacity, transfer properties, and enthalpy-entropy compensation of the examined systems. This research provides insights into the behavior of otic antiinfectives and contributes to the understanding of drug mixtures. [Extracted from the article]

A recent study conducted by the Vietnam Academy of Science and Technology has explored the potential of cyclotides, a type of peptide, in antibiotic research. Cyclotides are known for their durability and antibacterial properties, and two specific cyclotides, cycloviolacin O17 and mra30, were extracted from Viola dalatensis Gadnep. These cyclotides exhibited antibacterial effects on specific strains of bacteria, such as Staphylococcus aureus and Pseudomonas aeruginosa. The study concluded that the minimum inhibitory concentration (MIC) values of these cyclotides were significantly low, making them promising candidates for further research in the field of antibiotic treatment. [Extracted from the article]

A study conducted by the Industrial University of Ho Chi Minh City in Vietnam investigated the effects of crosslinking agents and molecular weight on the properties of cotton fabrics treated with chitosan for antibacterial purposes. Two types of chitosan with different molecular weights and two types of crosslinking agents were used. The study found that fabrics treated with lower molecular weight chitosan had more favorable finishing processes, although the whiteness of the treated samples was low. Cotton fabrics treated with citric acid exhibited better hygroscopicity and vapor transmission but had a more pronounced yellow color compared to those treated with dimethylol dihydroxyethyleneurea. The research provides insights into the bonding mechanism of cellulose-crosslinker-chitosan in antibacterial treated cotton fabrics. [Extracted from the article]

A study conducted by researchers at Ho Chi Minh City Open University in Vietnam examines the impact of purchasing sovereign bonds on bank risk in the Vietnamese banking sector. The study finds that banks that purchase securities issued by the domestic government tend to have lower risk, particularly during periods of crisis and uncertainty. The impact of sovereign bond holdings on bank risk is influenced by factors such as high-risk-weighted assets and low diversification. The findings of this study remain consistent across different measures of bank risk. [Extracted from the article]

A study conducted at Nguyen Tat Thanh University in Ho Chi Minh City, Vietnam, has explored the use of porous silicon nanoparticles (PSi NPs) in cancer therapy. The researchers synthesized PSi NPs from silica nanoparticles using a reduction process with magnesium powder. By attaching Fluorescein Isothiocyanate (FITC) to the surface of the PSi NPs, they enhanced their fluorescence intensity and stability, allowing for high-resolution imaging. The PSi NPs also demonstrated excellent photothermal effects, leading to significant cell death in targeted cancer cells upon near-infrared (NIR) light exposure. The findings suggest that PSi NPs have the potential to be multifunctional agents in cancer therapy, combining effective treatment with non-invasive imaging. [Extracted from the article]

A study conducted at the University of the Sciences in Ho Chi Minh City, Vietnam, focused on the synthesis and cytotoxicity of alkyl triphenylphosphonium pinostrobin derivatives in cancer research. Pinostrobin, a compound found in Boesenbergia rotunda, has demonstrated anti-proliferation and apoptosis effects in cancer stem-like cells. However, its hydrophobic properties limit its bioavailability. The study synthesized eight new derivatives and evaluated their cytotoxicity against the HepG2 liver cancer cell line. The derivatives exhibited moderate cytotoxicity and were more potent than pinostrobin and pinostrobin hydrazone. The research also identified key structural descriptors responsible for cytotoxicity and developed reliable models for predicting the cytotoxicity of other compounds. [Extracted from the article]

A study conducted by researchers at Nguyen Tat Thanh University in Ho Chi Minh City, Vietnam, explores the potential health benefits of cascara kombucha as a functional beverage. The study found that cascara kombucha effectively decreased free radicals, alpha-amylase, and lipase activity, suggesting its potential as an antioxidant and for modulating carbohydrate and lipid metabolism. In a mouse model, oral administration of cascara kombucha improved liver health, reduced fasting blood glucose levels, and lowered serum cholesterol content induced by a fat-enriched diet. The study concludes that cascara kombucha shows promise in addressing health issues caused by poor dietary habits and metabolic imbalances. [Extracted from the article]

A report from the Oxford University Clinical Research Unit investigates the 2017-2019 measles outbreak in the northern region of Vietnam. The study examines the association between vaccination rates and chronic diseases, as well as the role of hospital-acquired infections in the outbreak. The research finds that children with chronic diseases had a lower proportion of vaccination and a higher risk of hospital-acquired infections. The study emphasizes the importance of comprehensive vaccination guidelines and increasing parental awareness to protect vulnerable individuals. [Extracted from the article]

A recent study conducted at Van Lang University in Ho Chi Minh City, Vietnam, focused on the design, synthesis, and evaluation of novel compounds for their potential anti-breast cancer activities. The researchers synthesized a series of analogues and found that 13 out of 21 compounds showed significant cell growth inhibition in breast cancer cells. These potential analogues were also found to have favorable physicochemical and pharmacokinetic properties and the ability to target the beta-tubulin chain. The study provides a comprehensive understanding of the anticancer activities of these analogues and suggests their potential as anti-breast cancer agents that inhibit microtubule assembly. [Extracted from the article]

A study conducted by researchers at Ho Chi Minh City University of Education in Vietnam explores the relationship between job stress, work performance, and attitudes towards seeking professional psychological help among Vietnamese employees. The study surveyed 374 employees using random sampling and an online questionnaire. The findings reveal significant variations across variables such as forms of work, operating hours, education levels, monthly income, and the presence of a psychological counseling department within the company. The study emphasizes the importance of addressing barriers to seeking help, promoting work engagement, and fostering a healthy work-life balance for employee well-being and productivity. Further research and interventions in diverse contexts are needed. [Extracted from the article]

A study conducted by researchers at the University of the Sciences in Ho Chi Minh City, Vietnam, explored the potential skin whitening properties of Curcuma zedoaria, a traditional medicine. The study found that the ethyl acetate fraction of the plant extract exhibited antioxidant activity and inhibited melanin production and tyrosinase, an enzyme involved in melanogenesis. The extract also showed the ability to block the expression of melanogenesis-related genes. These findings suggest that Curcuma zedoaria has potential for use in skin-pigmentation treatment cosmetics. [Extracted from the article]