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The article discusses research by Salwa Bakr and colleagues from Fayoum University, reported in the Annals of Hematology issue on August 19, 2024. Topics include the role of adipocyte fatty acid-binding protein (FABP4) as a biomarker for predicting cardiometabolic events in thalassemia, its correlation with various clinical parameters, and its potential as a diagnostic tool for monitoring thalassemia-related organ damage.

A recent study conducted by the National Research Centre aimed to determine the impact of the deletion of the glutathione S-transferase class Mu 1 (GSTM1) gene on the risk of lung cancer among smokers. The study involved 20 patients with lung cancer and 20 healthy individuals as a control group. The results showed no statistically significant difference in the frequency of the GSTM1 null variant between the two groups, indicating no association between the occurrence of the GSTM1 null variant and the risk of lung cancer, even when stratified for smoking status. This research provides valuable insights into the genetic susceptibility of tobacco-related cancers. [Extracted from the article]

A recent study conducted at Mansoura University in Egypt examined the impact of an educational bundle on pediatric oncology nurses' knowledge and attitudes towards atraumatic care. The study found that the educational intervention significantly improved nurses' knowledge and attitudes, with positive effects lasting three months after the intervention. The researchers recommend regular update sessions and refreshment courses to maintain and further improve nurses' knowledge and attitudes over a longer period. This study highlights the importance of atraumatic care in pediatric nursing and suggests strategies for ongoing education in this area. [Extracted from the article]

A recent study conducted at Ain Shams University in Cairo, Egypt, examined the psychological aspects and quality of life in children and adolescents with cystic fibrosis (CF). The study found that CF patients experienced higher levels of depression and anxiety compared to their healthy peers. However, there were no significant differences in the quality of life between CF patients and healthy controls. The researchers concluded that annual symptom screening for psychiatric symptoms in children with CF is justified. This study provides important insights into the prevalence of psychiatric symptoms in CF patients. [Extracted from the article]

A recent study conducted at Cairo University in Egypt examined the effects of medium-chain triglyceride (MCT) formulas and supplementation on the growth and nutritional status of infants with biliary atresia (BA) who underwent the Kasai portoenterostomy (KPE) operation. The study found that nutritional counseling using MCT-containing formulas and supplementation improved the nutritional status and growth of the patients. Additionally, the study revealed low levels of vitamin D in the patients, which significantly increased after the intervention. The researchers concluded that dietary intervention and MCT and micronutrient supplementation can improve the nutritional status of children with BA following KPE. [Extracted from the article]

A study conducted by researchers from Jouf University in Saudi Arabia examined the prevalence, risk factors, and associations of cyberbullying with stress and mental well-being among high school students in Zagazig, Egypt. The study found that cyberbullying victimization was prevalent among high school students, with female students, those under 18 years old, those with lower educational achievement, and those with higher daily internet use being more likely to experience cyberbullying. Cyberbullied students reported higher levels of perceived stress and poorer mental well-being compared to non-cyberbullied students. The study suggests that targeted interventions and prevention strategies are needed to address cyberbullying and promote the well-being of adolescents in the digital age. [Extracted from the article]

A study conducted by researchers at Ain Shams University in Egypt examined the outcome of hepatocellular carcinoma (HCC) in patients with metabolic-associated fatty liver disease (MAFLD). The study compared the prognosis and survival rates of patients with MAFLD-related HCC to those with HCV-related HCC. The results showed no significant difference in the outcome or survival rates between the two groups, except for the levels of alpha-fetoprotein (AFP), which were higher in HCV patients. This study is the first of its kind in Egypt and Africa, and further research is needed to fully understand the nature and outcome of MAFLD-related HCC. [Extracted from the article]

A study conducted by Ain Shams University in Cairo, Egypt, explored the association between a specific gene polymorphism and non-cystic fibrosis bronchiectasis in children. The researchers found that there was no significant difference in the gene polymorphism between patients with bronchiectasis and the control group. However, they did observe that the level of lipoxin A4, a lipid mediator that regulates airway inflammation, was significantly lower in patients with bronchiectasis. The study suggests that the gene polymorphism may be a protective factor against the development and progression of bronchiectasis. [Extracted from the article]

A recent study conducted by Ain Shams University in Egypt aimed to adapt evidence-based clinical practice guidelines (CPGs) for chronic cough in children to suit the Egyptian healthcare context. The researchers used the Adapted ADAPTE methodological framework for guideline adaptation and adapted recommendations from three original CPGs. The adapted CPG provides applicable evidence-based recommendations for pediatricians and healthcare workers in Egypt. The study highlights the utility of guideline adaptation and collaboration between clinical and methodological experts. [Extracted from the article]

A recent study conducted at Al-Azhar University examined the role of serum myeloperoxidase (MPO) in predicting severe bronchial asthma. The study included 130 patients with asthma and 130 healthy controls. The researchers found that MPO levels were significantly higher in the asthma group compared to the control group. MPO levels were positively correlated with asthma severity and negatively correlated with respiratory function. The study concluded that MPO can be used as a biomarker for diagnosing asthma and assessing its severity, but further research is needed to confirm its role. [Extracted from the article]

A study conducted at Al-Azhar University in Egypt has adapted a clinical practice guideline for the diagnosis, treatment, and prevention of community-acquired pneumonia (CAP) in children. The study aimed to provide evidence-based guidance for managing CAP in Egypt by adapting existing guidelines to the local healthcare context. The adaptation process involved input from clinical content experts and methodologists, resulting in the development of the first national guideline for CAP in children in Egypt. The study highlights the efficiency of the Adapted ADAPTE method and emphasizes the importance of collaboration between clinical and methodological professionals in guideline adaptation. [Extracted from the article]

According to the news reporters, the research concluded: "These results suggested the protective effect of diacerein on PF relies on its antioxidant and anti-inflammatory effects reducing TLR4/NF-kB signaling pathway." Keywords: Health and Medicine; Human and Experimental Toxicology EN Health and Medicine Human and Experimental Toxicology 896 896 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on human and experimental toxicology. [Extracted from the article]

Keywords: Chalcogens; Health and Medicine; Risk and Prevention; Surgery EN Chalcogens Health and Medicine Risk and Prevention Surgery 2054 2054 1 09/11/23 20230911 NES 230911 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Current study results on chalcogens have been published. According to news reporting out of Birmingham, United Kingdom, by NewsRx editors, research stated, "This study assessed the potential cost-effectiveness of high (80-100%) vs low (21-35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. [Extracted from the article]

Autoimmune Diseases and Conditions, Autoimmune Diseases and Conditions of the Nervous System, CNS Demyelinating Autoimmune Disease, Demyelinating Diseases and Conditions, Health and Medicine, Immune System Diseases and Conditions, Multiple Sclerosis, Neuroimmunology, Neurology Keywords: Autoimmune Diseases and Conditions; Autoimmune Diseases and Conditions of the Nervous System; CNS Demyelinating Autoimmune Disease; Demyelinating Diseases and Conditions; Health and Medicine; Immune System Diseases and Conditions; Multiple Sclerosis; Neuroimmunology; Neurology EN Autoimmune Diseases and Conditions Autoimmune Diseases and Conditions of the Nervous System CNS Demyelinating Autoimmune Disease Demyelinating Diseases and Conditions Health and Medicine Immune System Diseases and Conditions Multiple Sclerosis Neuroimmunology Neurology 414 414 1 09/11/23 20230911 NES 230911 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Week -- Current study results on multiple sclerosis have been published. [Extracted from the article]

Keywords: Zagazig; Egypt; Africa; Bariatrics; Corpus Luteum Hormones; Diet and Nutrition; Gynecology; Health and Medicine; Nutrition Disorders; Nutritional and Metabolic Diseases and Conditions; Obesity; Overnutrition; Progesterone; Women's Health EN Zagazig Egypt Africa Bariatrics Corpus Luteum Hormones Diet and Nutrition Gynecology Health and Medicine Nutrition Disorders Nutritional and Metabolic Diseases and Conditions Obesity Overnutrition Progesterone Women's Health 1917 1917 1 08/28/23 20230901 NES 230901 2023 SEP 2 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Nutritional and Metabolic Diseases and Conditions - Obesity. Zagazig, Egypt, Africa, Bariatrics, Corpus Luteum Hormones, Diet and Nutrition, Gynecology, Health and Medicine, Nutrition Disorders, Nutritional and Metabolic Diseases and Conditions, Obesity, Overnutrition, Progesterone, Women's Health. [Extracted from the article]

Keywords: Health and Medicine; Medical Science EN Health and Medicine Medical Science 5285 5285 1 08/07/23 20230811 NES 230811 2023 AUG 11 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on medical science are presented in a new report. The patients were divided into two groups; TVR group (n=150) which included patients who underwent tricuspid valve replacement and TVr group (n=150) which included patients who underwent tricuspid valve repair. A prospective study was conducted on 300 consecutive patients with rheumatic heart disease showing severe tricuspid valve affection underwent tricuspid valve surgery, between 2014 and 2018. [Extracted from the article]