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A recent study conducted at University Hospital Basel in Switzerland aimed to explore the characteristics and outcomes of vessel perforation during thrombectomy, a procedure used to remove blood clots. The study included 459 patients with vessel perforation, and the primary outcome measured was the modified Rankin Scale (mRS) at 90 days. The study found that vessel perforation during thrombectomy is a severe and often fatal complication, with a mortality rate of 51.9% at 90 days. However, the study did not find a significant association between thrombolysis (a treatment to dissolve blood clots) and worse prognosis. Prompt cessation of active bleeding within 20 minutes was identified as critical for patient outcomes. The study emphasizes the importance of training interventionalists in managing complications during thrombectomy. [Extracted from the article]

A recent study conducted at the University of Washington in Seattle explored the biological basis behind the treatment outcomes of cerebral aneurysms using flow diverting stents (FDS). The researchers created patient-specific 3D models of aneurysms and used computational fluid dynamics to analyze the impact of FDS on hemodynamic flow. They found significant changes in gene transcription in endothelial cells (ECs) after FDS placement, particularly related to aneurysm hemodynamics. Further investigation is needed to understand the relationship between these transcriptional changes and treatment outcomes. This research provides valuable insights into the potential mechanisms underlying the effectiveness of FDS in treating cerebral aneurysms. [Extracted from the article]

A recent study conducted at the Medical University of South Carolina examined the outcomes of mechanical thrombectomy (MT) in patients with medium-vessel occlusions (MEVOs) in the posterior cerebral artery (PCA). The study analyzed data from the Stroke Thrombectomy and Aneurysm Registry (STAR) and found that successful recanalization rates were similar between PCA MEVOs and middle cerebral artery (MCA) MEVOs. However, patients with PCA MEVOs were less likely to undergo intra-arterial thrombolysis or achieve successful recanalization. The researchers concluded that further study and innovation may be necessary to improve successful PCA MEVO recanalization rates. [Extracted from the article]

A recent study conducted at the University of Washington examined the safety of intracranial venous stenting in patients with nickel allergy. Nickel hypersensitivity is a common metal-related allergy, and nickel-containing alloys are often used in endovascular devices. The study found that the use of nickel-containing stents in intracranial venous sinuses did not result in any allergic reactions or adverse outcomes in patients with nickel allergy. All patients reported clinical improvement in their symptoms, and follow-up imaging showed that all stents remained patent. This limited case series suggests that intracranial venous stenting may be safe for patients with nickel allergy. [Extracted from the article]

A recent report from the University of Washington explores the Circle of Willis (CoW), a network of blood vessels in the brain, and its role in vasospasm, the constriction of blood vessels that can lead to stroke. The study used computational fluid dynamics simulations to analyze the localization and severity of vasospasm in 25 patients. The researchers found that changes in collateral flow directions were observed in some patients with localized vasospasm, while others did not experience significant changes. The study suggests that further research could investigate the relationship between vasospasm and clinical outcomes such as the development of infarct. [Extracted from the article]

A recent study conducted by researchers from the University of Utah explores the management of intracranial aneurysms that have not been successfully treated with flow diversion within 6-24 months. The study involved a panel of 67 international experts who participated in a Delphi consensus process to determine the best course of action for these cases. The experts reached a consensus on various aspects, including the definition of treatment failure at specific time points and preferred treatment options. The study provides valuable insights into the management of intracranial aneurysms and offers guidance for future research in this field. [Extracted from the article]

A recent study conducted by researchers at the Medical University of South Carolina compared the outcomes of mechanical thrombectomy (MT) for patients with stroke who had a low Alberta Stroke Program Early Computed Tomography Score (ASPECTS). The study analyzed data from a large multicenter international registry from 2013 to 2023 and found that there was no significant difference in acceptable outcomes at 90 days between patients who underwent MT within 6 hours or 6 to 24 hours after stroke onset. However, the rate of symptomatic intracranial hemorrhage was higher in the early window group. The study suggests that MT provides a similar benefit to functional outcome for patients presenting within different time windows. [Extracted from the article]

A recent study conducted by researchers at the University of Utah compared the diagnostic value of head computed tomography angiography (CTA) and digital subtraction angiography (DSA) in the diagnosis of penetrating cerebrovascular injury. The study found that cerebrovascular injury is common after penetrating brain injury, and CTA alone is insufficient for diagnosing these injuries. Patients with penetrating brain injuries should routinely undergo DSA. The study included 73 patients, with an incidence of 45.2% of penetrating cerebrovascular injury. The specific types of injuries identified included pseudoaneurysms, major arterial occlusions, dural venous sinus occlusions, dural arteriovenous fistulas, and carotid cavernous fistulas. The sensitivity of CTA was 36.4%, and the specificity was 85.0%. Overall, 5.6 DSA studies were needed to identify a lesion requiring treatment that had not been identified with CTA. [Extracted from the article]

A recent study conducted at the Hospital of the University of Pennsylvania compared the outcomes of general anesthesia (GA) versus non-general anesthesia (non-GA) in middle meningeal artery embolization (MMAE) procedures for chronic subdural hematomas (cSDH). The study found that there were no significant differences in radiological improvement or clinical outcomes between GA and non-GA for MMAE. The research involved 778 patients who underwent 956 MMAE procedures at 14 North American centers. The study suggests that the choice of anesthesia type for MMAE procedures should be left to the care team's discretion, as there are no standard guidelines. [Extracted from the article]

A study conducted by researchers at the University of California Los Angeles (UCLA) has found that abnormal intracranial aneurysm (IA) wall motion is associated with IA growth and rupture. The researchers used a new image processing algorithm called amplified Flow (aFlow) to track IA wall motion by combining cine and four-dimensional (4D) Flow MRI. The study included 10 patients with growing IAs and a matched cohort of 10 patients with stable IAs. The results showed that aFlow-derived quantitative assessment of IA wall motion demonstrated greater wall motion and higher variability of wall deformation in growing IAs compared to stable IAs. [Extracted from the article]

A new report discusses research findings on cerebral infarction, specifically focusing on the outcomes of mechanical thrombectomy (MT) in stroke patients with low Alberta Stroke Program Early Computed Tomography Score (ASPECTS). The study analyzed data from the Stroke Thrombectomy and Aneurysm Registry (STAR) and found that achieving a modified Thrombolysis in Cerebral Infarction (mTICI) 2c/3 score after MT was associated with a more favorable 90-day outcome compared to achieving an mTICI 2b score. These findings suggest that mTICI 2c/3 may be a better target for MT in patients with low ASPECTS. [Extracted from the article]

A new report discusses research conducted at the Medical University of South Carolina on the outcomes of mechanical thrombectomy (MT) for acute ischemic stroke (AIS) patients with low Alberta Stroke Program Early CT Score (ASPECTS). The study compared the outcomes of AIS patients with ASPECTS 2-3 and ASPECTS 4-5. The research found that AIS patients with ASPECTS 2-3 had similar outcomes compared to those with ASPECTS 4-5. This study provides valuable insights into the treatment of AIS patients with low ASPECTS. [Extracted from the article]

Researchers at the University of Washington have conducted a study on the use of smartphone pupillometry for the detection of acute large vessel occlusion (LVO) in patients with acute ischemic stroke (AIS). The study found significant alterations in pupillary light reflex (PLR) parameters in AIS patients with LVO before thrombectomy, suggesting the potential use of smartphone pupillometry for LVO detection. The study compared PLR parameters in healthy controls and AIS patients and analyzed the proprietary Neurological Pupil index (NPi) score. The research has been peer-reviewed and published in the Journal of Stroke and Cerebrovascular Diseases. [Extracted from the article]

2024 SEP 7 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on stroke is the subject of a new report. According [...]

2024 FEB 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Cerebrovascular Diseases and Conditions - Stroke are discussed in [...]

2024 JAN 6 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on Surgery - Thrombectomy is now available. According to [...]