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1. Synthesis of (plus or minus)-calicheamicinone by two methods

5. Synthesis and structure–activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold

6. Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis

7. Enantioselective total synthesis of asidophytine

8. Highly enantioselective phase transfer catalyzed alkylation of a 3-oxygenated propionic ester equivalent: applications and mechanism

9. Synthesis of (+ or -)-calicheamicinone by two related methods

10. Optimization of Potency and Pharmacokinetic Properties of Tetrahydroisoquinoline Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists

12. Correction to Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

13. Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

14. Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases

15. Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists

16. Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure–Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives

20. Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate

21. Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of trans-Cinnamides

22. Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

23. Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists

24. Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides

25. Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of N-Aryl Cinnamides

28. Optimization of Potency andPharmacokinetic Propertiesof Tetrahydroisoquinoline Transient Receptor Potential Melastatin8 (TRPM8) Antagonists.

33. Selective Class I Phosphoinositide3-KinaseInhibitors: Optimization of a Series of Pyridyltriazines Leading tothe Identification of a Clinical Candidate, AMG 511.

34. Structure-Based Designof a Novel Series of Potent, Selective Inhibitors of the Class IPhosphatidylinositol 3-Kinases.

35. Fused Piperidines as aNovel Class of Potent and OrallyAvailable Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists.

36. Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure–Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives.

40. Synthesis of (...)-Calicheamicinone by Two Methods.

41. Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

42. Synthetic studies on calicheamicin γ<SUB>1</SUB><SUP>I</SUP>—synthesis of(−)-calicheamicinone and models representing the four sugars and the aromatic system

47. Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate.

48. Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H-benzimidazoles.

49. Discovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides.

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