Synthetic studies on calicheamicin γ<SUB>1</SUB><SUP>I</SUP>—synthesis of(−)-calicheamicinone and models representing the four sugars and the aromatic system

The synthesis of (−)-calicheamicinone (2), the carbohydrates 88, 101, 111, 119 and 120, and the hexasubstituted benzene 139, is described; these compounds formally represent the subunits of the antitumor antibiotic calicheamicin γ₁^I (1).