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Byline: Manjinder. Sidhu, Kunal. Jain, Sandhya. Sood, Harpreet. Kaur Aggressive angiomyxoma (AAM) is a rare mesenchymal locally aggressive tumor arising in the pelvis and perineal region in females. On the [...]

Researchers at the All India Institute of Medical Sciences (AIIMS) conducted a study on a rare variant of cardiac myxoma in a woman who presented with acute stroke. The study highlighted the challenges in diagnosing cystic masses in the heart and emphasized the importance of surgical excision to prevent complications such as stroke and hemorrhage. The findings were published in The Egyptian Heart Journal and can be accessed for free online. The research underscores the significance of prompt diagnosis and treatment in cases of cardiac myxoma to prevent serious complications. [Extracted from the article]

Researchers at Yantai Yuhuangding Hospital in China reported a case of a 56-year-old man with atrial myxoma and a coro-cameral fistula arising from its feeding branch. The patient underwent surgical resection of the tumor and repair of the fistula, with successful outcomes and no recurrence after 6 months. This rare case highlights the importance of timely diagnosis and treatment of atrial myxomas to prevent complications. For more information, readers can access the full article in Frontiers in Cardiovascular Medicine. [Extracted from the article]

A recent study conducted at Sarawak General Hospital in Malaysia has provided new insights into myxomas, which are rare cardiac tumors. The study found that myxomas can lead to severe complications such as intracardiac obstruction, emboli, and constitutional symptoms. However, surgical excision of myxomas is associated with excellent outcomes and a low rate of recurrence. The researchers reported a case where early detection of a myxoma through point-of-care ultrasound allowed for prompt intervention and successful surgical removal. The patient had a favorable prognosis and minimal residual symptoms after the procedure. [Extracted from the article]

A recent report discusses research findings on myxomas, which are the most common primary benign heart tumors. While they are typically found in the left atrium, this case report describes a rare instance of a myxoma in the right ventricle causing both inflow and outflow obstruction. The patient presented with exertional dyspnea and underwent surgical resection, resulting in a successful recovery. The research emphasizes the importance of timely diagnosis through imaging techniques like echocardiography and highlights surgical resection as the definitive treatment with excellent outcomes and low recurrence rates. [Extracted from the article]

A new report discusses research findings on heart failure, specifically focusing on atrial myxomas, which are rare cardiac tumors that often present with unrelated symptoms. The report presents a case study of a farmer who presented with typical symptoms of heart failure, but echocardiography revealed a large mass in his left atrium, suspected to be an atrial myxoma. The researchers propose surgical excision of the mass as a cure, which would eliminate the need for continuous medical therapy. The report highlights the mechanisms by which atrial myxomas can cause heart failure and the various clinical presentations of these tumors. [Extracted from the article]

The article presents a rare case where a myxoma in the right ventricular outflow tract was initially misdiagnosed as pulmonary thromboembolism. The patient's history of acute lymphoblastic leukemia and symptoms of dyspnea and edema led to incorrect initial treatment, with the correct diagnosis made after surgery revealed the myxoma.

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The article offers information on a rare case of a large left atrial myxoma presenting with gastrointestinal symptoms. Topics discussed include the unusual gastrointestinal presentation of atrial myxomas; the potential role of interleukin-6 in these symptoms; and also mentions about the importance of early detection and treatment to prevent severe complications.

The article discusses research by Zedong Jiang from Sichuan University, reported in the August 19, 2024 issue of Signal Transduction and Targeted Therapy, on the immune microenvironment's role in cardiac myxoma progression. Topics include a single-cell analysis revealing distinct fibroblast-like myxoma cells, the impact of M2-like macrophages and immune suppression on embolism, and potential targets for intervention in the treatment of cardiac myxomas.

A recent study from Tulane University in New Orleans, United States, has presented new findings on thrombosis. The study describes a case of a 41-year-old man with sepsis and bacteraemia who developed an in-situ right atrial thrombus that mimicked an atrial myxoma. The researchers used cardiac magnetic resonance imaging (CMR) to differentiate between the thrombus and myxoma. The study highlights the importance of CMR in characterizing such masses and distinguishing between thrombi and myxomas. [Extracted from the article]

A recent study conducted by researchers at Saglik Bilimleri Universitesi has found that cardiac myxoma, a benign tumor of the heart, is most commonly diagnosed in the left atrium. However, in rare cases, it can also occur in the right atrium or ventricles. The size, mobility, and location of the tumor determine the symptoms experienced by patients. The study also reported a case of right ventricular myxoma complicated by stroke, which was successfully treated through surgical removal of the tumor and closure of a patent foramen ovale. [Extracted from the article]

A recent study conducted by researchers at Fujian Medical University in Fuzhou, China, aimed to investigate the cellular composition and gene expression of cardiac myxoma, the most common primary cardiac tumor in adults. The researchers used single-cell sequencing to analyze tissue samples from surgically resected cardiac myxoma cases. They identified different cell populations in glandular and nonglandular myxoma and found active communication between T cells and epithelial cells. These findings provide insights into the heterogeneity of cardiac myxoma and may contribute to improved clinical diagnosis and treatment. The study was supported by the National Natural Science Foundation of China. [Extracted from the article]

A recent study from the University Hospital Center Zagreb in Croatia provides insights into the diagnosis and imaging techniques for cardiac myxomas, which are the most common benign cardiac neoplasms. The study highlights the use of echocardiography as the first-line imaging modality for analyzing cardiac masses, while emphasizing the need for additional imaging techniques such as cardiac magnetic resonance imaging (MRI) and computed tomography (CT) to confirm the diagnosis and evaluate tissue characteristics. The researchers also discuss the differential diagnoses and provide tips on differentiating myxomas from other cardiac masses. This information is valuable for individuals conducting research on cardiology and oncology. [Extracted from the article]

A recent report from the All India Institute of Medical Sciences (AIIMS) discusses the challenges of managing airways in pediatric patients with oral tumors. The report focuses on a case of a 1-year-old child with a mandibular odontogenic myxoma, a rare tumor in the jaw. Due to the distorted anatomy and limited cooperation from pediatric patients, conventional awake fiberoptic intubation is not always possible. The researchers recommend proper planning and thorough examinations for successful airway management in pediatric patients with similar conditions. [Extracted from the article]

A recent report from Rochester General Hospital discusses a rare case of myxoma involving the pulmonary valve. The patient, a 66-year-old female with lung cancer and chronic obstructive pulmonary disease, presented with acute shortness of breath. Imaging revealed a large vascular tumor on the ventricular side of the pulmonary valve. Due to high surgical risk, the tumor was removed using a percutaneous approach guided by transesophageal echocardiography. The pathology confirmed the mass to be a myxoma. The study suggests that percutaneous resection may be a feasible option for high-risk surgical patients with valvular masses. [Extracted from the article]

A recent study conducted at Princess Royal University Hospital discusses the diagnosis of a large hemangioma in the interatrial septum, a rare occurrence. The case involved a 41-year-old patient who was admitted due to a stroke, and a transthoracic echocardiogram revealed a mass in the right atrium adhered to the interatrial septum. Surgical intervention confirmed the presence of a hemangioma. The study emphasizes the rarity of cardiac hemangiomas and the importance of histopathological examination for an accurate diagnosis. For more information, the full article can be accessed through the Journal of Cardiothoracic Surgery. [Extracted from the article]

A recent study conducted at Mohammed V Military Hospital explores the link between cardiac myxoma and cerebral vasculitis. The researchers present a case study of a 49-year-old male patient who experienced sudden weakness in his legs and slurred speech. Further examination revealed multiple acute ischemic strokes and cerebral vasculitis. The patient was diagnosed with left atrial myxoma and underwent open-heart surgery. The study emphasizes the importance of early diagnosis and highlights the challenges in identifying cardiac myxomas due to their ability to mimic other conditions. [Extracted from the article]

A recent study conducted at Albany Medical Center in New York explored the rare occurrence of stroke in pediatric patients caused by a cardiac myxoma thromboembolism. The study found that there is a lack of evidence-based guidelines for managing pediatric strokes due to their low incidence and limited clinical trials. The researchers performed a systematic review and identified 19 reported cases of pediatric myxoma causing stroke, with 36.8% of patients between the ages of 4 and 14 undergoing neurosurgery. The study provides insight into the safe use of mechanical thrombectomy as a treatment for pediatric strokes caused by thromboembolism. [Extracted from the article]

A recent report from the University of Texas Health Science Center discusses the case of a 72-year-old woman with non-small cell lung adenocarcinoma who was found to have an atrial mass during an imaging evaluation for lung cancer progression. The report highlights the challenges faced by the treatment team in differentiating between distinct types of masses, especially in the presence of an existing malignancy. The research emphasizes the complex decision-making involved in diagnosing and timing interventions for patients with frailty and a fast-growing cardiac mass. For more information, the full article can be accessed for free through the Cardio-Oncology journal. [Extracted from the article]

A recent study from the Divisione di Cardiologia provides new insights into heart failure caused by a giant right atrial myxoma. Myxomas are the most common benign tumors of the heart, with about 75% occurring in the left atrial cavity. However, they can also appear in the right atrium, although this is less common. The study presents a case report of an 88-year-old female patient with a large right atrial myxoma, which was discovered incidentally and was causing symptoms of heart failure. The patient underwent surgery to remove the mass, and her condition improved. The study highlights the importance of accurate diagnosis using techniques such as transthoracic and transesophageal echocardiogram and cardiac magnetic resonance imaging. The researchers conclude that cardiac MRI has become the gold standard for evaluating cardiac masses before histology. [Extracted from the article]

2022 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Fresh data on fibroma are presented in a new report. According to [...]

A recent study conducted at Government Dental College in Chhattisgarh, India, has reported on a rare case of peripheral odontogenic myxoma (POM) involving the orbital and zygoma region. The patient, a 16-year-old male, presented with a painless swelling in his left infratemporal region. The tumor was diagnosed as POM and was successfully removed through surgery, with no recurrence observed during the 2.5-year follow-up period. This case is significant as it represents only the second reported instance of POM in the infratemporal region and the first reported case of myxoma extending into the zygomatic region and lateral wall of the orbit. For more information, the full article can be accessed for free at the provided link. [Extracted from the article]

A recent study conducted by researchers from the Medical University of Graz in Austria focused on distinguishing between cellular myxoma and low-grade myxofibrosarcoma, two types of soft tissue tumors. The study utilized methylation analysis and molecular analysis on cellular myxomas and myxofibrosarcomas. The results showed that cellular myxomas have distinct methylation patterns and GNAS mutations, while myxofibrosarcomas have copy number variations. The study highlights the diagnostic potential and limitations of molecular analysis in differentiating between these two tumors and suggests further research to improve the accuracy of diagnostic tools. [Extracted from the article]

A recent study conducted by researchers at Kuwait University focused on a rare condition called carotid artery myxoma, which can lead to stroke. The study reported a case of a 39-year-old female patient with Sjogren Syndrome who experienced a stroke due to a myxoma in her carotid artery. The patient underwent surgery to remove the tumor, and further investigations showed no residual tumor or potential cardiac source. The researchers concluded that carotid artery myxoma should be considered as a potential cause of carotid artery stenosis and cerebral ischemia, although it is extremely rare. [Extracted from the article]

A new report from Tokyo Medical University Ibaraki Medical Center in Japan discusses the rare occurrence of renal embolisms caused by cardiac myxomas. The report presents a case study of a 69-year-old woman who experienced renal infarction due to a left atrial myxoma. The patient underwent hemodialysis and anticoagulant therapy before the myxoma was surgically removed, leading to an improvement in renal function. The report emphasizes the importance of prompt treatment depending on the location of the embolism. [Extracted from the article]

A recent study conducted in Maharashtra, India, explores the clinicopathologic correlation in a rare presentation of odontogenic myxoma (OM). The study emphasizes the association between clinical manifestations and pathological features of OM. The research involved a 25-year-old male who presented with lower left jaw pain, and through clinical examination, imaging, and histopathological analysis, a diagnosis was made. The study highlights the importance of a multidisciplinary approach and contributes to the understanding of OM's etiologies. [Extracted from the article]

A recent report from LMU Hospital in Munich, Germany, discusses the case of a 25-year-old French woman who presented with dyspnea at Munich's Octoberfest. The woman was found to have large masses in both her left and right atrium, connected by an atrial septal defect. The masses were successfully removed through emergent cardiac surgery. The report emphasizes the importance of a quick diagnosis and prompt surgery in managing atrial myxomas. [Extracted from the article]

A recent report from Carol Davila University of Medicine and Pharmacy in Bucharest, Romania, describes a unique case of a gigantic left ventricular myxoma resulting in embolic acute lower limb ischemia in a pediatric patient. The patient, an 11-year-old female with a history of acute lymphoblastic leukemia, presented with acute pain and loss of sensitivity in both legs. Physical examination revealed suspicion of bilateral lower leg ischemia, which was confirmed by Doppler arterial ultrasound. Emergency surgery and anticoagulant therapy were performed, resulting in complete restoration of arterial blood flow and successful management of the condition. Despite the rarity of cardiac myxomas in the pediatric population, this case highlights the importance of prompt assessment and treatment in cases of peripheric embolism. [Extracted from the article]

A recent study from Martin, Slovakia, has reported on a case of a fast-growing myxoma in the left atrium of a 50-year-old woman. The patient initially presented with dyspnea and was diagnosed with severe mitral obstruction caused by a large polypoid mass in the left atrium. Urgent cardiac surgery was performed to successfully remove the tumor, which was confirmed to be a cardiac myxoma. The study highlights the potential for misdiagnosed signs of pulmonary edema caused by mitral obstruction. For more information, the full article can be accessed through the European Journal of Case Reports in Internal Medicine. [Extracted from the article]

A recent report from Wroclaw, Poland discusses a case of a 3.5-year-old boy who was diagnosed with right atrial myxoma shortly after starting treatment for inflammatory bowel disease. Right atrial myxomas are extremely rare in pediatric patients, and the coexistence of inflammatory bowel disease and cardiac myxoma has not been previously reported. The study highlights the need for further research to establish a potential correlation between these two diseases. The report provides valuable insights into the relationship between inflammatory bowel disease and cardiac myxoma in pediatric patients. [Extracted from the article]

A recent report from Showa University Fujigaoka Hospital discusses the findings of a case study on myxomas, which are rare cardiac tumors. The study focused on a male patient in his 80s with advanced chronic kidney disease who was found to have a rapidly growing right atrial myxoma. The tumor, measuring 37 mm x 28 mm, was discovered during an echocardiogram and was surgically removed. This case is notable because the patient is the oldest reported case of a rapidly growing right atrial tumor. For more information, the full article can be accessed for free at the Renal Replacement Therapy journal website. [Extracted from the article]

A recent study conducted in Aichi, Japan, reported on a rare case of a cardiac myxoma, a benign tumor, in a small dog. The dog presented with growth insufficiency, lethargy, and a cardiac murmur. The researchers performed simultaneous surgeries to remove the tumor and close a ventricular septal defect. The dog survived for 11 years after the surgery with no cardiac complications. This case is significant as it is the first reported use of retrograde cardioplegia during open-heart surgery in a small-breed dog. [Extracted from the article]

A recent report discusses the findings of a study on fibromyxomas conducted by researchers at Guangdong Medical University in Zhanjiang, China. The study focuses on a case of subungual superficial acral fibromyxoma in a 74-year-old woman who had a tumor on her right big toe. The examination revealed a red tumor of about 3.0 cm x 2.0 cm x 1.0 cm in size at the nail bed, along with other histological changes. The tumor was successfully removed through surgery, and no recurrence was observed. For more information, readers can refer to the journal article provided. [Extracted from the article]

A patent application has been submitted for a "Multi-Armed Myxoma Virus" that could potentially improve cancer treatments. The application describes a genetically engineered virus that includes specific proteins to disrupt certain genes and enhance its anti-cancer properties. The application provides detailed information on the structure and composition of the virus. The genetically engineered virus has shown reduced expression of certain proteins in infected cells compared to control viruses. [Extracted from the article]

A recent study conducted by researchers at the University of Sydney explores the relationship between left atrial (LA) shape and stroke. The study focuses on Embolic Stroke of Undetermined Source (ESUS), a condition that results in significant morbidity. The researchers hypothesized that LA shape varies depending on the cause of stroke, specifically cardioembolic stroke (CE) secondary to atrial fibrillation (AF) versus ESUS. The study found that alterations in LA shape, particularly increased spherical remodeling, were present in ESUS, AF, and CE patients. The findings suggest that novel markers of LA sphericity may help identify LA myopathy in ESUS patients and guide management for secondary prevention. [Extracted from the article]

A recent study from Largo Medical Center has provided new insights into cardiogenic shock, a condition that occurs following a heart attack. The study focused on a case of a 58-year-old male who experienced cardiogenic shock after a myocardial infarction. It was discovered that the patient had a left atrial myxoma, a type of tumor that can obstruct blood flow through the mitral valve. The findings highlight the importance of early detection and treatment of atrial myxomas to prevent complications such as heart failure and stroke. [Extracted from the article]

A research study conducted at MS Ramaiah Medical College in Karnataka, India, provides new insights into myxomas, which are rare tumors that can cause cardiac outflow obstruction and embolic events. The study focuses on the successful anesthetic management of a 65-year-old female patient with an incidental left atrial myxoma who required proximal femur nailing. The patient had no significant cardiac history and underwent general anesthesia with invasive blood pressure monitoring to allow for timely fracture reduction. The study's findings can be found in the Saudi Journal of Anaesthesia. [Extracted from the article]

A recent report from ABVIMS and Dr. RML Hospital in New Delhi, India discusses the management of a patient with a ruptured aneurysm and an asymptomatic atrial myxoma, a rare cardiac tumor. The researchers emphasize the importance of early surgical resection of atrial myxomas due to potential complications such as intracardiac obstruction, embolus, and metastasis. They also highlight the association between atrial myxomas and the development of metastatic intracranial aneurysms, a rare complication. The case study presented involves a 42-year-old female patient with subarachnoid hemorrhage who underwent repair of a left paraclinoid internal carotid artery aneurysm under general anesthesia with a left interatrial septum myxoma. For more information, readers can refer to the Journal of Current Research in Scientific Medicine. [Extracted from the article]

A recent study conducted at Chungbuk National University Hospital in South Korea focused on conjunctival myxoma, a rare benign tumor that can be mistaken for other common conjunctival lesions. The study describes a case of a 55-year-old woman who initially presented with a painless mass in her left eye, which was misdiagnosed as a conjunctival cyst. The tumor was successfully excised, and the patient remained healthy without any recurrence or systemic abnormalities. The researchers emphasize the importance of considering myxoma as a possible diagnosis for conjunctival lesions and highlight the need for surgical excision and systemic evaluation to prevent potential underlying conditions. [Extracted from the article]

A recent report from J.N. Medical College discusses a case of a juxta-articular myxoma, a benign tumor commonly associated with larger joints. The case involved a 30-year-old male patient with a myxoma at the metacarpophalangeal joint of the thumb. The tumor was diagnosed through ultrasound and X-ray, and was successfully removed through surgery. Six months after the surgery, the patient had full range of motion without pain. This case adds to the limited number of reported cases involving myxomas in the hand. [Extracted from the article]

A study conducted by the All India Institute of Medical Sciences (AIIMS) in Delhi, India, explores the use of 3D transesophageal echocardiography in distinguishing between a clot and a myxoma, which are cardiac masses that can cause significant health issues. The researchers found that while clinical correlation and transthoracic echocardiography are typically used for preoperative diagnosis, 3D echocardiography offers advantages such as multiplanar cropping abilities and superior imaging quality. This technology can help differentiate between a clot and a myxoma, even in cases where the location or morphology is atypical. The study provides valuable insights for the diagnosis and treatment of cardiac masses. [Extracted from the article]

A recent study conducted in Yunnan, People's Republic of China, examined the challenges of safely inducing anesthesia in a patient with a giant right atrial myxoma at moderate altitude. The study emphasized the importance of adequate volume preload therapy and the use of echocardiography to prevent hemodynamic compromise. The research also highlighted the observation that post-tumor removal hypotension may not necessarily result in decreased oxygen saturation. These findings have significant implications for the perioperative care of patients with giant right atrial myxoma at moderate altitudes. [Extracted from the article]

A recent report from researchers in Nantong, People's Republic of China, discusses the diagnosis and treatment of a rare case of a cystic myxoma, a benign cardiac tumor. The report highlights the importance of careful differential diagnosis and pathological examination in accurately identifying and treating such tumors. The study emphasizes the need for further research in this area to improve understanding and management of primary cardiac tumors. For more information, readers can refer to the original article published in Frontiers in Cardiovascular Medicine. [Extracted from the article]

A recent report from the Permanente Medical Group discusses the dermatologic manifestations of atrial myxoma, a type of heart tumor. The report describes a case of a 28-year-old woman who presented with skin lesions on her hands, feet, and face, along with an ischemic stroke. Skin biopsies revealed inflammation without vasculitis, and further examination identified a 2.4 cm atrial myxoma. The report suggests that these skin changes should be considered embolic rather than constitutional symptoms, and emphasizes the importance of early diagnosis to prevent complications such as stroke. [Extracted from the article]

A recent report from the University of Malaya discusses the characteristics, management, and treatment options for superficial acral fibromyxoma, a slow-growing, benign soft tissue tumor. The condition typically occurs in middle-aged individuals but has been reported across a wide range of ages, with males being more commonly affected. The report emphasizes the importance of a minimum two-year follow-up to accurately assess recurrence rates and avoid undertreatment. The purpose of the article is to provide readers with a better understanding of the tumor's characteristics, including bone involvement, as well as diagnostic strategies and treatment options. [Extracted from the article]

A recent case report and literature review from Gifu University Hospital highlights the rapid expansion of a left atrial myxoma caused by acute multiple internal hemorrhages. Left atrial myxoma is the most common benign tumor, but its growth rate is unknown as specific symptoms do not appear until the tumor reaches a certain size. The case study describes a 64-year-old woman who experienced a sudden deterioration in her respiratory condition due to the rapid morphological changes of the tumor. The researchers emphasize the importance of recognizing the potential risk of internal hemorrhage in these supposedly slow-growing benign tumors. [Extracted from the article]

A study conducted at Northern Jiangsu People's Hospital in China has found that cardiac myxoma, a rare condition, can be a cause of ischemic stroke, particularly in young individuals. The researchers reported a case of acute cerebral infarction caused by multiple myxomas in the left atrium and right ventricle. The patient underwent emergency surgery and had a satisfactory prognosis. The study aims to raise awareness about the evaluation and treatment of acute cerebral infarction in individuals with cardiac myxoma. [Extracted from the article]

A recent study conducted by researchers at Baskent University explored the effectiveness and safety of Myxoma virus (MYXV) in multiple myeloma (MM) cell lines and primary myeloma cells obtained from patients. The study found that treating Myxoma virus with lenalidomide and bortezomib resulted in reduced cell viability and increased caspase-9 expression, indicating increased apoptosis. The addition of MYXV also led to a statistically significant increase in early apoptosis in both newly diagnosed and refractory MM patients. These findings suggest that patient-based therapy should be considered for the effective management of MM. [Extracted from the article]