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The article emphasizes the significance of itch science and its implications for understanding various health conditions. It discusses the complexities of chronic itching, its neurological underpinnings and how advances in neuroimmunology have led to potential therapies for itch-related disorders, shedding light on broader sensory and medical insights.

The article focuses on the role of TL1A in promoting a multi-cytokine Th9 cell phenotype that enhances allergic inflammation in asthma. Topics include the mechanism by which TL1A induces IL-9 and IL-13 co-expressing Th9 cells, the impact of TL1A signaling on transcription factor binding and histone modifications, and the potential for targeting TL1A to modify asthma-related allergic responses.

A recent study conducted by researchers at the University of Maryland School of Medicine has shed light on the development of chronic pruritus (CP), a condition characterized by intense itching without a primary skin eruption. The study focused on the triggers and pathophysiology of CP following exposure to an immune stimulus, such as checkpoint inhibitors or vaccination. The researchers found that patients with immune-stimulated CP had elevated levels of certain cytokines, including interleukin-5 and thymic stromal lymphopoietin. However, the study had limitations due to its small sample size. This research provides valuable insights into the development of CP and the alterations in blood markers associated with the condition. [Extracted from the article]

Researchers from Majmaah University in Saudi Arabia have conducted a study on the development of a potential mucosal adjuvant vaccine for human respiratory syncytial virus (RSV) infection. RSV is a common cause of respiratory illnesses and hospitalizations among infants and young children, but an effective vaccine is currently unavailable. The researchers focused on the use of thymic stromal lymphopoietin (TSLP) cytokine, which can activate B-cells and stimulate antibody production, to produce robust and long-lasting mucosal responses to respiratory virus infection. They suggest that a mucosal vaccine using TSLP as an immunostimulant with the RSV Fusion protein (RSV-F) could enhance the local adaptive immune response and increase viral clearance from airways. However, further investigations are needed to determine the challenges and limitations of using TSLP cytokine as an immunostimulant. [Extracted from the article]

This article provides information about a newly launched clinical trial, NCT06525597, which aims to evaluate the efficacy and safety of Stapokibart injection in patients with allergic rhinitis. Allergic rhinitis is a chronic inflammatory disease of the nasal mucosa that is mainly mediated by immunoglobulin E (IgE) in atopic individuals exposed to allergens. The trial is a randomized, double-blind, placebo-controlled phase II study and is currently not yet recruiting participants. The primary outcome measure of the study is the mean change from baseline in daily reflective total nasal symptom scores (rTNSS) over 4 weeks of treatment. [Extracted from the article]

A patent application has been submitted for a method of generating T cell precursors from hematopoietic stem and progenitor cells. The method involves contacting the cells with an agonist for tumor necrosis factor receptor 2 (TNFR2). The invention aims to enhance the generation of T cell precursors, which are important for immune function. The patent application provides details on the specific methods and systems involved in this process. [Extracted from the article]

A recent study conducted by researchers at the University of Alberta in Canada explored the expression of alarmin cytokines in the upper airways of individuals with asthma. The study involved 40 participants with asthma, divided into four groups based on the severity of their condition. The researchers found that patients with more severe asthma (GINA 5) had significantly higher levels of thymic stromal lymphopoietin (TSLP) in their nasal, buccal, and throat epithelial cells compared to patients with less severe asthma (GINA 1-4). This study provides new insights into the role of alarmin cytokines in asthma and highlights the potential importance of TSLP in the upper airways of individuals with severe asthma. [Extracted from the article]

A patent has been issued for a biologic treatment for cancer, specifically acute lymphoblastic leukemia (ALL). ALL is the most common cancer in children and adolescents, and the survival rate for relapsed cases is less than 50%. The majority of ALL cases are the B-cell type, and a genetic alteration called CRLF2 B-ALL is associated with poor outcomes, particularly in Hispanic children. The patent describes methods for treating cancer patients by administering a therapeutically effective amount of human thymic stromal lymphopoietin (TSLP). [Extracted from the article]

A patent application has been submitted for a composition called tezepelumab, which is a monoclonal antibody that targets a cytokine called thymic stromal lymphopoietin (TSLP). TSLP is associated with asthma and inflammation. The application discusses the attributes of tezepelumab and its derivatives, including their impact on antibody tolerability and potency. The composition aims to have greater potency and tolerability by reducing the amount of certain derivatives. The patent application provides detailed information about the composition and its potential use in inhibiting respiratory hypersensitivity and asthma. For more information, refer to the full patent application. [Extracted from the article]

The article offers information about the International Task Force on Canine Atopic Dermatitis, defines canine AD as a genetically predisposed inflammatory and pruritic allergic skin disease with characteristic clinical features associated with immunoglobulin E (IgE) antibodies. It discusses that Canine AD, a multifactorial, noncurable disease.

A study conducted at Bern University Hospital investigated the effects of dupilumab, an interleukin (IL)-4/IL-13 receptor blocker, on autophagy and lysosomal degradation in patients with atopic dermatitis (AD). The researchers found that autophagy, which is important for epidermal differentiation, is impaired in AD. However, treatment with dupilumab was shown to reduce skin inflammation, restore the skin barrier, and normalize key proteins involved in autophagy and lysosomal function. This study provides further evidence that autophagy is inhibited in lesional AD skin due to lysosomal dysfunction, and that dupilumab therapy can restore dysregulated autophagy. [Extracted from the article]

A report from the University of Genoa discusses the role of thymic stromal lymphopoietin (TSLP) in the immune response to environmental insults and its involvement in chronic diseases such as asthma and chronic rhinosinusitis. The report highlights the potential of monoclonal antibodies, specifically Tezepelumab, in targeting TSLP and preventing its interactions with receptors. Clinical trials are currently underway to evaluate the safety and efficacy of Tezepelumab in various inflammatory disorders. This research provides valuable insights into the functional role of TSLP and its suitability as a target for biological therapies. [Extracted from the article]

A patent application has been submitted by inventors Gearing, Guo, Li, Petaipimol, and Wang for pharmaceutical compositions containing antibodies that bind to the TSLP receptor (TSLP-R) and their use in treating diseases. The application describes different concentrations of the antibodies, buffers, excipients, surfactants, and amino acids. These compositions aim to inhibit TSLP and improve treatment for TSLP-related diseases. The application provides detailed information on the antibody's amino acid sequences and their potential medical applications. For more information, please refer to the full patent application. [Extracted from the article]

A recent study from the University of Miami explores the similarities and differences in the peripheral mechanisms underlying itch and pain in atopic dermatitis (AD). AD is a skin condition characterized by intense itching, and more than 40% of patients also experience skin pain. The study found that itch and pain share many similarities in the peripheral nervous system, including common mediators, receptors, and ion channels. However, there are also distinct differences between itch and pain signaling, such as specific immune responses associated with each sensation. Understanding the connection between itch and pain mechanisms may provide new insights into the treatment of chronic pain and itch in AD. [Extracted from the article]

Researchers at Sharda University in Greater Noida, India have identified three potential dual inhibitors for thymic stromal lymphopoietin (TSLP) and interleukin-33 (IL-33) proteins, which play important roles in allergic diseases. The study used structure-based virtual screening and molecular dynamics simulations to evaluate the binding affinity, stability, and safety of these compounds. The identified compounds, ZINC01105767, ZINC08764679, and ZINC33833100, show promising potential as anti-allergy agents and could lead to the development of more effective therapies for allergic diseases. Further investigations and experimental validations are needed to confirm these findings. [Extracted from the article]

A study conducted at the First Affiliated Hospital in Anhui, China, explored the role of thymic stromal lymphopoietin (TSLP) in fungal keratitis, a condition characterized by corneal inflammation caused by fungal infection. The researchers found that TSLP secretion by corneal cells was associated with increased inflammation in macrophages. Treatment with recombinant TSLP resulted in the upregulation of proinflammatory markers in macrophages, indicating a polarization towards a pro-inflammatory phenotype. The study suggests that TSLP plays a role in the pathogenesis of fungal keratitis by influencing macrophage polarization through the nuclear factor kappa B (NF-KB) signaling pathway. [Extracted from the article]

A recent report from the University of Texas McGovern Medical School explores the role of Thymic Stromal Lymphopoietin (TSLP) in cutaneous disorders. TSLP is an important cytokine that activates immune responses and is associated with pruritus in various skin conditions, particularly atopic dermatitis. The report discusses the potential of TSLP as a biomarker for monitoring disease progression in discoid lupus erythematosus and explores pharmacological treatments targeting TSLP, including its potential role in the treatment of alopecia areata. The research provides an overview of TSLP's background, structure, and functions, with a focus on its association with cutaneous disorders and the impact of the atopic march. [Extracted from the article]

A recent study conducted by researchers at Wroclaw Medical University in Poland explored the potential of thymic stromal lymphopoietin (TSLP) and interleukin 33 (IL-33) as biomarkers for mild asthma in children. The study involved 52 pediatric patients with mild bronchial asthma and a control group of 26 non-asthmatic children. The researchers found that serum TSLP concentrations were significantly lower in asthmatic subjects compared to the control group, particularly in atopic asthma patients. However, no significant differences were observed in serum IL-33 concentrations between the two groups. The study concluded that IL-33 and TSLP may not be ideal biomarkers for mild asthma in children, but further research on their association with asthma is needed. [Extracted from the article]

A patent has been issued for nanosensors and methods for detecting biological markers, specifically active proteins, in a sample. The invention aims to improve the detection of clinically relevant biological markers for diseases and conditions, such as asthma and lung diseases. The nanosensors consist of detectable and quencher particles, and they are designed to detect changes in the detectable particle signal upon contact with the sample, indicating protein activity. The patent also describes a microfluidic device for detecting biological markers and methods for isolating exosomes and detecting various biological markers associated with infection, inflammation, and cancer. This invention has the potential to enhance specificity and diagnostic power in detecting and monitoring disease progression. [Extracted from the article]

A report from the Medical University of Gdansk discusses the need for reliable biomarkers in personalized medicine for atopic dermatitis (AD). The researchers highlight the potential of tape stripping (TS) as a minimally invasive method to obtain biomarkers. They identify several biomarkers, including thymic stromal lymphopoietin (TSLP), interleukin (IL)-13, CC chemokine ligand 17 (CCL17)/thymus and activation-regulated chemokine (TARC), stratum corneum (SC) lipids, and nitric oxide synthase 2 (NOS2)/inducible nitric oxide synthase (iNOS). However, none of these biomarkers have been validated or implemented into routine clinical practice yet. Further research is needed to develop a precise approach to AD patients. [Extracted from the article]

A recent study conducted at Taizhou University in Zhejiang, China, has found that fibroblast-derived Thymic Stromal Lymphopoietin (TSLP) plays a significant role in promoting the metastasis of ovarian cancer. The researchers discovered that TSLP is upregulated in fibroblasts and its receptor is significantly upregulated in immune cells in the metastatic microenvironment. Inhibition of TSLP reduced the migration of immune cells and the formation of metastatic foci, indicating its crucial role in promoting ovarian cancer metastasis by altering the immune microenvironment and stimulating a type 2 immune response. This study provides a theoretical basis for developing novel therapeutic strategies and targeted treatments for TSLP. [Extracted from the article]

According to a preprint abstract, researchers have found that thymic stromal lymphopoietin (TSLP) may play a role in the development of endometriosis. TSLP is involved in cell proliferation and inflammation in various diseases. The study found that TSLP expression was elevated in endometriotic lesions compared to control samples, and that TSLP treatment promoted cell proliferation and reduced apoptosis in cell lines. In a mouse model, TSLP treatment induced a Th2 immune response and increased lesion proliferation. These findings suggest that TSLP may modulate the endometriotic lesion microenvironment and contribute to lesion development. However, it is important to note that this research has not yet undergone peer review. [Extracted from the article]

A study conducted by researchers at Huazhong University of Science and Technology in Wuhan, China, has found that thymic stromal lymphopoietin (TSLP) may play a role in reducing neuroinflammation in the central nervous system. The researchers used a model of LPS-stimulated microglia to investigate the impact of TSLP on microglial activation and found that TSLP treatment increased the expression of TSLP receptors and reduced oxidative stress, inflammation, and the expression of M1-type markers in microglia. TSLP also influenced the differentiation of microglia towards the M2 type and suppressed LPS-induced activation through the JAK2/STAT5 pathway. The study suggests that targeting TSLP could be a novel strategy for controlling inflammation in the central nervous system. [Extracted from the article]

A recent study conducted at the University of Naples Federico II in Italy has explored the role of thymic stromal lymphopoietin (TSLP) in asthma. TSLP is expressed by epithelial cells and exists in two variants: the long form (lfTSLP) and a shorter isoform (sfTSLP). The study found that mast cells and macrophages in the human lung play important roles in asthma, and that tryptase and chymase, enzymes released by mast cells, cleave TSLP. The study also discovered that TSLP fragments generated by these enzymes do not activate human lung macrophages. These findings contribute to a better understanding of asthma pathobiology. [Extracted from the article]

A recent study conducted by researchers at the University of Maryland School of Medicine has examined the immune profiles of individuals with prurigo nodularis (PN), a chronic inflammatory skin disease. The study found that there are differences in immune profiles based on race and peripheral blood eosinophil count. Specifically, certain biomarkers were elevated in PN patients compared to healthy controls, and PN patients with higher eosinophil counts had higher levels of Th2 markers. Additionally, the study found that individuals who responded well to Th2 targeted therapies were more likely to be Caucasian or Asian and had higher eosinophil counts. These findings suggest that blood eosinophil count and race may be associated with immune profiles and response to treatment in PN. [Extracted from the article]

A recent study conducted by researchers at the University of Florida aimed to assess the potential toxicity of microplastic fibers (MPFs) on human lung epithelial cells. The researchers grew and differentiated primary human bronchial epithelial cells at an air-liquid interface and exposed them to dyed and undyed polyester MPFs. The results showed that the MPFs did not significantly decrease cell viability, but did lead to changes in the expression of asthma-associated genes. The study is one of the first to investigate the impact of MPFs on lung cells and provides insights into the potential pro-inflammatory pathways targeted by MPF exposure. [Extracted from the article]

A recent study conducted at Hospital General Universitario Reina Sofia in Murcia, Spain, explored the use of tezepelumab in the treatment of severe asthma. Asthma affects a significant portion of the population, with 3%-10% of patients experiencing severe symptoms. Tezepelumab is a monoclonal antibody that targets the cytokine thymic stromal lymphopoietin (TSLP), reducing inflammation and improving asthma control. The drug has shown promising results in reducing asthma exacerbations, improving quality of life, and enhancing lung function. This research provides valuable insights into the potential use of tezepelumab as a treatment option for severe uncontrolled asthma. [Extracted from the article]

A study conducted by researchers at the University of Cincinnati explores the role of the cytokine thymic stromal lymphopoietin (TSLP) in eosinophilic esophagitis (EoE), a disease associated with variants in TSLP. The study found that TSLP directly stimulates human CD4(+) T cells and contributes to allergic inflammation. The researchers discovered that TSLP increased the proliferation of CD4(+) T cells, enhanced type 2 cytokine production, and modified gene expression. The findings suggest that TSLP inhibitors may have therapeutic value in treating EoE. [Extracted from the article]

A recent study conducted by researchers at Newcastle University in Australia has found that endoplasmic reticulum (ER) stress may play a role in the development of severe uncontrolled asthma. The study focused on the induction of thymic stromal lymphopoietin (TSLP), a cytokine that regulates immune responses in the lungs. The researchers discovered that ER stress signaling induces TSLP mRNA expression, which is further enhanced by TLR3 activation. These findings suggest that targeting ER stress with pharmacological interventions could potentially provide new treatments for severe asthma. [Extracted from the article]

A recent study conducted at Pennsylvania College of Optometry at Salus University explores the role of cytokines in allergic conjunctivitis, a common immune hypersensitivity disorder that affects the ocular system. The researchers highlight the variability of clinical manifestations based on environmental factors, seasonal dynamics, and genetic predisposition. The study provides a comprehensive description of various interleukins and thymic stromal lymphopoietin, elucidating their pathophysiological roles in mediating allergic immune responses on the ocular surface. The findings suggest that understanding the functions of these cytokines could lead to innovative therapeutic approaches for managing allergic conjunctivitis. [Extracted from the article]

A study conducted by researchers at Hallym University College of Medicine in South Korea investigated the protective effect of a compound called DMOG on skin inflammation. The study found that DMOG treatment reduced inflammation in a mouse model of type 2 skin inflammation. This effect was accompanied by a downregulation of certain cytokines, including TSLP and IL-33, and a decrease in reactive oxygen species (ROS) levels. The researchers concluded that DMOG downregulates TSLP and ROS through the HIF pathway, thereby reducing skin inflammation. Further research is needed to explore the potential therapeutic applications of DMOG in treating skin inflammation. [Extracted from the article]

A recent study conducted by Sungkyunkwan University School of Medicine in Seoul, South Korea, has found that skin biomarkers can predict the development of food allergies in early life. The researchers collected skin tape strips from newborns and analyzed them for lipidomic and cytokine markers. They found that certain lipids and cytokines were dysregulated in infants who went on to develop food allergies. This non-invasive analysis at 2 months of age could potentially identify infants at risk of future food allergies. [Extracted from the article]

MedImmune Limited has been issued a patent for dry powder formulations of thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of use. The patent describes a dry powder formulation containing microparticles with leucine, trileucine, and an antigen binding fragment of an anti-TSLP antibody. This formulation can be administered via inhalation for the treatment of asthma. The patent provides detailed information on the composition and characteristics of the dry powder formulation. [Extracted from the article]

A new study conducted by researchers at the "Iuliu Hatieganu" University of Medicine and Pharmacy in Cluj-Napoca, Romania, explores the role of alarmins in chronic spontaneous urticaria (CSU) and their impact on disease severity and quality of life (QoL) for patients. The study analyzes the levels of interleukin-25 (IL-25), interleukin-33 (IL-33), and thymic stromal lymphopoietin (TSLP) in CSU patients and compares them to healthy controls. The findings suggest that elevated levels of IL-33 and TSLP in CSU patients may play a significant role in the pathogenesis of CSU and that IL-33 could serve as a potential biomarker for diagnosis and severity assessment. Further research is needed to confirm these findings and explore IL-33 as a therapeutic target for CSU. [Extracted from the article]

A recent report from National Jewish Health in Denver, Colorado discusses the findings on atopic dermatitis (AD), which is the most common chronic inflammatory skin disease. The report highlights that skin barrier dysfunction is the main cause of AD and is influenced by genetic mutations, immune pathway activation, altered host defense mechanisms, and environmental factors. The research suggests that understanding the mechanisms behind skin barrier dysfunction can lead to the development of new treatments for AD. The report has been peer-reviewed and can be found in The Journal of Allergy and Clinical Immunology In Practice. [Extracted from the article]

A study conducted by researchers at the University of South China explores the role of hormones in allergic airway inflammation. The study focuses on group 2 innate lymphoid cells (ILC2s), which produce cytokines crucial for processes such as inflammation and tissue repair. The researchers found that hormones synthesized by the body can modulate the proliferation and function of ILC2s during allergic airway inflammation. The study discusses the effects of multiple hormones on ILC2-driven inflammation and their potential therapeutic significance. This research has been peer-reviewed and provides valuable insights into the immune response in allergic airway inflammation. [Extracted from the article]

A patent has been issued for bicyclic peptide ligands specific for TSLP (thymic stromal lymphopoietin), a cytokine involved in the pathogenesis of asthma. The invention provides a peptide ligand that binds to TSLP and a pharmaceutical composition containing the ligand. The ligand can be used to prevent, suppress, or treat diseases or disorders mediated by TSLP. Asthma is a common long-term inflammatory disease of the airways, and there is a need for therapeutic agents to alleviate its symptoms. The patent was filed by BicycleTx Limited and published in January 2024. [Extracted from the article]

A recent study conducted by ViGenCell Inc. in Seoul, South Korea, explored the therapeutic efficacy of myeloid suppressor cells derived from human cord blood in treating atopic dermatitis (AD). The study found that these cells demonstrated immunosuppressive effects and significantly reduced the severity of AD symptoms in mice. They also improved skin barrier function and reduced inflammation. The findings suggest that myeloid suppressor cells from human cord blood could be a promising novel treatment strategy for AD. [Extracted from the article]

A patent application has been filed for a pharmaceutical composition that includes an anti-human TSLP receptor antibody. This composition is intended to be administered intravenously or subcutaneously and aims to provide stability and prevent undesirable effects. The patent application describes different formulations and conditions to achieve this stability. The composition is specifically designed to treat asthma and minimize the generation of unwanted substances. It includes specific amino acid sequences, post-translational modifications, and other components to ensure its effectiveness. This invention aims to offer a reliable and effective treatment option for individuals with asthma. [Extracted from the article]

A recent study conducted by researchers at Gachon University in South Korea explored the effects of membrane-free stem cell components derived from adipose-derived stem cells (ADSCE) on atopic dermatitis (AD) in mice. AD is a common inflammatory skin disorder characterized by skin barrier dysfunction and an imbalance in the immune response. The study found that the administration of ADSCE resulted in significant improvements in dermatitis score, epidermal thickness, transepidermal water loss, and serum levels of immunoglobulin E. ADSCE treatment also upregulated the expression of skin barrier proteins and inhibited the infiltration of mast cells and the expression of thymic stromal lymphopoietin. The researchers concluded that ADSCE showed potential as a therapeutic treatment for AD. [Extracted from the article]

Researchers at the Institut Universitaire de Cardiologie et de Pneumologie de Quebec have published new data on asthma. The study focused on the effects of bronchial thermoplasty (BT) on gene signatures in bronchial epithelial cells (BECs) of severe asthmatics. The researchers found that BT downregulated the expression of the S100A gene family and related downstream signaling pathways, suggesting that BT may improve asthma control by reducing the expression of these genes. Further research is needed to fully understand the biological mechanisms behind this improvement. [Extracted from the article]

A recent study conducted by the University of Andres Bello in Santiago, Chile, explored the association between atopic dermatitis (AD) and periodontitis. The study examined the levels of interleukins (IL)-13, IL-31, and thymic stromal lymphopoietin (TSLP) in the gingival crevicular fluid (GCF) of 29 subjects with moderate-to-severe AD and 33 controls. The results showed that the GCF levels of IL-31 and TSLP were higher in AD subjects compared to controls, while there were no significant differences in the GCF levels of IL-13. The study suggests that AD and periodontitis independently influence the GCF levels of IL-31 in opposing ways, while AD alone influences the levels of TSLP. Further research is needed to understand the mechanisms underlying these associations. [Extracted from the article]

The news reporters obtained a quote from the research from the Eunice Kennedy Shriver National Institute of Child Health, "Amnion epithelial cells (AEC), Ureaplasma parvum, and Sneathia spp. were also utilized. Keywords: Bethesda; United States; North and Central America; Gram-Negative Bacteria; Health and Medicine; Immunology; Inflammation; Mycoplasmataceae; Mycoplasmatales; Ureaplasma EN Bethesda United States North and Central America Gram-Negative Bacteria Health and Medicine Immunology Inflammation Mycoplasmataceae Mycoplasmatales Ureaplasma 2303 2303 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Gram-Negative Bacteria - Ureaplasma have been published. [Extracted from the article]

Keywords: Houston; State:Texas; United States; North and Central America; Antibodies; Bispecific Antibodies; Blood Proteins; Immunoglobulins; Immunology; Immunoproteins; Proteins EN Houston State:Texas United States North and Central America Antibodies Bispecific Antibodies Blood Proteins Immunoglobulins Immunology Immunoproteins Proteins 1502 1502 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Immunology - Antibodies. Then we present and evaluate the anti-tumor characteristics of 1B7/CD3, a novel CD3-redirecting bispecific antibody (BsAb) that co-targets TSLPR. [Extracted from the article]

Cytokines, Immunology, Intercellular Signaling Peptides and Proteins, Interferons Keywords: Cytokines; Immunology; Intercellular Signaling Peptides and Proteins; Interferons EN Cytokines Immunology Intercellular Signaling Peptides and Proteins Interferons 2940 2940 1 10/09/23 20231010 NES 231010 2023 OCT 13 (NewsRx) -- By a News Reporter-Staff News Editor at Immunotherapy Weekly -- A new study on interferons is now available. [Extracted from the article]

Keywords: Ohio; Diarrhea; Cincinnati; Immunology; United States; Food Allergen; Food Allergies; Gastroenterology; Atopic Dermatitis; Health and Medicine; North and Central America; Skin Diseases and Conditions; Immune System Diseases and Conditions EN Ohio Diarrhea Cincinnati Immunology United States Food Allergen Food Allergies Gastroenterology Atopic Dermatitis Health and Medicine North and Central America Skin Diseases and Conditions Immune System Diseases and Conditions New research on Immune System Diseases and Conditions - Food Allergies is the subject of a report. For more information on this research see: TSLP rather than IL33 drives food allergy following epicutaneous sensitization to food allergen. [Extracted from the article]

Asthma, Bronchial Diseases and Conditions, Health and Medicine, Immune System Diseases and Conditions, Lung Diseases and Conditions, Obstructive Lung Diseases and Conditions, Respiratory Hypersensitivity, Respiratory Tract Diseases and Conditions Keywords: Asthma; Bronchial Diseases and Conditions; Health and Medicine; Immune System Diseases and Conditions; Lung Diseases and Conditions; Obstructive Lung Diseases and Conditions; Respiratory Hypersensitivity; Respiratory Tract Diseases and Conditions EN Asthma Bronchial Diseases and Conditions Health and Medicine Immune System Diseases and Conditions Lung Diseases and Conditions Obstructive Lung Diseases and Conditions Respiratory Hypersensitivity Respiratory Tract Diseases and Conditions 507 507 1 09/25/23 20230929 NES 230929 2023 SEP 29 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Researchers detail new data in asthma. [Extracted from the article]

Keywords: Cells; Drugs and Therapies; Nerve Injury; Nervous System Diseases and Conditions; Neurologic Manifestations; Neurons; Neuropathic Pain; Neuropathy; Pain; Pharmaceuticals EN Cells Drugs and Therapies Nerve Injury Nervous System Diseases and Conditions Neurologic Manifestations Neurons Neuropathic Pain Neuropathy Pain Pharmaceuticals 1943 1943 1 09/19/23 20230918 NES 230918 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Gene Therapy Weekly -- Investigators discuss new findings in nerve injury. Nerve injury-induced gene expression changes in the dorsal root ganglion (DRG) were examined using RNA sequencing. [Extracted from the article]

Zhejiang, People's Republic of China, Asia, Allergic Rhinitis, Allergies, Allergy Research, Epithelial Cells, Health and Medicine, Immune System Diseases and Conditions, Intercellular Signaling Peptides and Proteins, Intermediate Filament Proteins, Nose Diseases and Conditions, Otorhinolaryngologic Diseases and Conditions, Respiratory Tract Diseases and Conditions, Respiratory Tract Infections, Rhinitis, Transforming Growth Factors, Vimentin Keywords: Zhejiang; People's Republic of China; Asia; Allergic Rhinitis; Allergies; Allergy Research; Epithelial Cells; Health and Medicine; Immune System Diseases and Conditions; Intercellular Signaling Peptides and Proteins; Intermediate Filament Proteins; Nose Diseases and Conditions; Otorhinolaryngologic Diseases and Conditions; Respiratory Tract Diseases and Conditions; Respiratory Tract Infections; Rhinitis; Transforming Growth Factors; Vimentin EN Zhejiang People's Republic of China Asia Allergic Rhinitis Allergies Allergy Research Epithelial Cells Health and Medicine Immune System Diseases and Conditions Intercellular Signaling Peptides and Proteins Intermediate Filament Proteins Nose Diseases and Conditions Otorhinolaryngologic Diseases and Conditions Respiratory Tract Diseases and Conditions Respiratory Tract Infections Rhinitis Transforming Growth Factors Vimentin 1406 1406 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Respiratory Therapeutics Week -- Current study results on Immune System Diseases and Conditions - Allergic Rhinitis have been published. [Extracted from the article]

Keywords: Philadelphia; State:Pennsylvania; United States; North and Central America; Antigen-Presenting Cells; Dendritic Cells; Diet and Nutrition; Health and Medicine; Immunology; Mononuclear Phagocyte System; Vitamins EN Philadelphia State:Pennsylvania United States North and Central America Antigen-Presenting Cells Dendritic Cells Diet and Nutrition Health and Medicine Immunology Mononuclear Phagocyte System Vitamins 1996 1996 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Immunology - Mononuclear Phagocyte System have been presented. Philadelphia, State:Pennsylvania, United States, North and Central America, Antigen-Presenting Cells, Dendritic Cells, Diet and Nutrition, Health and Medicine, Immunology, Mononuclear Phagocyte System, Vitamins. [Extracted from the article]