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167 results on '"Monokine"'

17. monokine.

Abstract

A definition of the medical term "monokine" is presented. Monokine refers to a chemical mediator released by monocytes and macrophages during the immune response. Monokines affect the growth and activity of other white blood cells. Interleukin-1 is an important monokine. The definition is from the "Taber's Cyclopedic Medical Dictionary," published by F.A. Davis Co.

Published
2005

18. Monokine.

Author

Vohr, Hans-Werner

Subjects
*MONOKINES, *DEFINITIONS, *CYTOKINES, *MACROPHAGES, *ANTIGEN presenting cells
Abstract

A definition of the term "monokine" is presented. It refers to a cytokine released from monocytes and macrophages.

Published
2005

21. Identification of Phenotype-Defining Gene Signatures Using the Gene-Pair Matrix Based Clustering.

Author

Lee, Chung-Wein, Li, Shuyu Dan, Su, Eric W., and Liao, Birong

Abstract

Mining the ˵meaningful″ clues from vast amount of expression profiling data remains to be challenge for biologists. After all the statistical tests, biologists often struggle deciding how to do next with a large list of genes without any obvious theme of mechanism, partly because most statistical analyses do not incorporate understanding of biological systems before hand. Here, we developed a novel method of ˵gene –pair difference within a sample″ to identify phenotype-defining gene signatures, based on the hypothesis that a biological state is governed by the relative difference among different biological processes. For gene expression, it is relative difference among the genes within a sample (an individual, cell, etc), the highest frequency of occurrences a gene contributing to the within sample difference underline the contributions of genes in defining the biological states. We tested the method on three datasets, and identified the most important gene-pairs to drive the phenotypic differences. [ABSTRACT FROM AUTHOR]

Published
2006
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