51 results on '"Scott Nicholson"'
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2. A Biomass Pyrolysis Oil as a Novel Insect Growth Regulator Mimic for a Variety of Stored Product Beetles
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Alexander Bruce, A Nolan Wilson, Sabita Ranabhat, Jaden Montgomery, Scott Nicholson, Kylee Harris, and William R Morrison
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Insecticides ,Tribolium ,Insecta ,Ecology ,fungi ,General Medicine ,Coleoptera ,Juvenile Hormones ,Insect Science ,Insect Repellents ,Larva ,Animals ,Biomass ,Pyrolysis - Abstract
As fumigants face increasing regulatory restrictions, resistance, and consumer pushback, it is vital to expand the integrated pest management (IPM) chemical toolkit for stored products. The production of biomass derived insecticides (e.g., bio-oil fraction) from byproducts of biofuel production may be a promising alternative source of chemistries for controlling stored product insects. These potential insecticidal bio-oils were fractionated based on boiling points (ranging from 115 to 230°C in one series and 245–250°C in another). Fractions were analyzed using GC-MS, and were found to be unique in composition. The lethality of these fractions was tested on Tribolium castaneum, Tribolium confusum, and Oryzaephilus surinamensis (L.) (Coleoptera: Silvanidae). Fractions were tested at concentrations ranging from 5–260 mg/ml to screen for efficacy against adults for durations of 2–8 hr sprayed on concrete arenas. In addition, a separate assay evaluated adult emergence of larvae after 6 wk with supplemental food in arenas, while repellency was evaluated against four stored product insect species in a laminar wind tunnel. A greenhouse gas (GHG) emissions life cycle assessment was also performed, which found the use of the bio-oil fraction could reduce GHG emissions associated with the insecticide supply chain by 25–61% relative to a fossil-fuel based insecticide or pyrethroid. While adults were largely unaffected, we found that larval emergence was significantly suppressed compared to controls by roughly half or more. We also determined that there was minimal repellency to most fractions by most species. We conclude that the use of bio-oil fractions is a climate-friendly choice that may support IPM programs.
- Published
- 2021
3. How ethical hacking can protect organisations from a greater threat
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Scott Nicholson
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021110 strategic, defence & security studies ,Certified Ethical Hacker ,General Computer Science ,business.industry ,020204 information systems ,Internet privacy ,0211 other engineering and technologies ,0202 electrical engineering, electronic engineering, information engineering ,02 engineering and technology ,business ,Law - Abstract
As digital technologies are becoming embedded in all aspects of life, cyber attacks can come from many directions. A significant proportion of these attacks pose serious risks to critical data, infrastructure and processes within all manner of organisations, both large and small.
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- 2019
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4. The Los Angeles 100% Renewable Energy Study (LA100): Chapter 8. Greenhouse Gas Emissions
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Scott Nicholson, David Keyser, Marissa Walter, Greg Avery, and Garvin Heath
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- 2021
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5. The ClosER study: results from a three-year pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes, 2011–2014
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Sally Pilling, Mark H. Wilcox, K. Morris, Jane Freeman, Sharie Shearman, Jonathan Vernon, Scott Nicholson, and Christopher Longshaw
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DNA, Bacterial ,0301 basic medicine ,Microbiology (medical) ,030106 microbiology ,Microbial Sensitivity Tests ,Drug resistance ,Tigecycline ,Biology ,Ribotyping ,Microbiology ,03 medical and health sciences ,Antibiotic resistance ,Drug Resistance, Bacterial ,Prevalence ,medicine ,Humans ,Fidaxomicin ,Longitudinal Studies ,Molecular Epidemiology ,Antiinfective agent ,Microbial Viability ,Clostridioides difficile ,Clindamycin ,General Medicine ,Anti-Bacterial Agents ,Europe ,Metronidazole ,Infectious Diseases ,Epidemiological Monitoring ,Clostridium Infections ,Vancomycin ,medicine.drug - Abstract
Objectives: Until the introduction of fidaxomicin, antimicrobial treatment for Clostridium difficile infection (CDI) was limited to metronidazole and vancomycin. The changing epidemiology of CDI and the emergence of epidemic C. difficile PCR ribotype 027 necessitate continued surveillance to identify shifts in antibiotic susceptibility. ClosER, currently the largest pan-European epidemiological study of C. difficile ribotype distribution and antibiotic susceptibility, aimed to undertake antimicrobial resistance surveillance pre- and post-introduction of fidaxomicin.\ud \ud \ud \ud Methods: Between July 2011 and July 2014, 39 sites across 22 European countries submitted 2830 C. difficile isolates for ribotyping, toxin testing and susceptibility testing to metronidazole, vancomycin, fidaxomicin, rifampicin, moxifloxacin, clindamycin, imipenem, chloramphenicol and tigecycline.\ud \ud \ud \ud Results: Ribotypes 027, 014, 001, 078, 020, 002, 126, 015 and 005 were most frequently isolated, and emergent ribotypes 198 and 356 were identified in Hungary and Italy, respectively. All isolates were susceptible to fidaxomicin, with scarce resistance to metronidazole (0.2%, 6/2694), vancomycin (0.1%, 2/2694) and tigecycline (0%). Rifampicin, moxifloxacin and clindamycin resistance was evident in multiple ribotypes. Lack of ribotype diversity correlated with greater antimicrobial resistance. Epidemic ribotypes (027/001) were associated with multiple antimicrobial resistance, and ribotypes 017, 018 and 356 with high-level resistance. Additional factors may also influence local ribotype prevalence.\ud \ud \ud \ud Conclusions: Fidaxomicin susceptibility was retained post-introduction, and resistance to metronidazole and vancomycin was rare. Continued surveillance is needed, with more accurate classification and clarification of ribotype subtypes to further understand their role in the spread of resistance. Other factors may also influence changes in prevalence of C. difficile ribotypes with reduced antibiotic susceptibility.
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- 2018
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6. Creating Engaging Escape Rooms for the Classroom
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Scott Nicholson
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Teamwork ,030504 nursing ,Teaching method ,media_common.quotation_subject ,05 social sciences ,050301 education ,Education ,03 medical and health sciences ,Forge ,Learner engagement ,Management of Technology and Innovation ,Pedagogy ,Developmental and Educational Psychology ,Narrative ,Sociology ,0305 other medical science ,0503 education ,Game theory ,Recreation ,media_common - Abstract
New ways to engage students in learning can be most meaningful if we provide opportunities for them to engage with each other and forge an understanding of the narrative behind the lessons.
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- 2018
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7. Bringing Escape Room Concepts to Pathophysiology Case Studies
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S. Richelle Monaghan and Scott Nicholson
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Cognitive science ,Psychology ,Pathophysiology - Published
- 2017
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8. Introduction
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Anna Serra-Llobet, G. Mathias Kondolf, Kathleen Schaefer, and Scott Nicholson
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- 2018
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9. Ballot Position, Choice Fatigue, and Voter Behaviour
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Scott Nicholson and Ned Augenblick
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Economics and Econometrics ,Actuarial science ,Natural experiment ,Exploit ,Status quo ,media_common.quotation_subject ,05 social sciences ,Face (sociological concept) ,CONTEST ,0506 political science ,Microeconomics ,Ballot ,Voting ,0502 economics and business ,050602 political science & public administration ,Economics ,Position (finance) ,050207 economics ,media_common - Abstract
In this paper, we examine the eect of "choice fatigue"on decision making. We exploit a natural experiment in which voters face the same contest at dierent ballot positions due to dierences in the number of local issues on their ballot. Facing more decisions before a given contest signi…cantly increases the tendency to abstain or rely on decision shortcuts, such as voting for the status quo or the …rst listed candidate. We estimate that, without choice fatigue, abstentions would decrease by 8%, and 6% of the propositions in our dataset would have passed rather than failed.
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- 2015
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10. Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model
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Caroline H. Chilton, Simon D. Baines, Scott Nicholson, Grace S. Crowther, Mark H. Wilcox, Sharie L. Todhunter, and Jane Freeman
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Microbiology (medical) ,Chemostat ,Biology ,Gut flora ,digestive system ,Indigenous ,Microbiology ,Feces ,Vancomycin ,Antimicrobial chemotherapy ,Pharmacology (medical) ,Microbiome ,Spores, Bacterial ,Pharmacology ,Clostridioides difficile ,Clindamycin ,Microbiota ,Biofilm ,Reproduction spores ,Clostridium difficile ,Plankton ,biology.organism_classification ,humanities ,Anti-Bacterial Agents ,Intestines ,Infectious Diseases ,Biofilms - Abstract
Biofilms are characteristic of some chronic or recurrent infections and this mode of growth tends to reduce treatment efficacy. Clostridium difficile infection (CDI) is associated with a high rate of recurrent symptomatic disease. The presence and behaviour of C. difficile within intestinal biofilms remains largely unexplored, but may factor in recurrent infection.A triple-stage chemostat gut model designed to facilitate the formation of intestinal biofilm was inoculated with a pooled human faecal emulsion. Bacterial populations were allowed to equilibrate before simulated CDI was induced by clindamycin (33.9 mg/L, four times daily, 7 days) and subsequently treated with vancomycin (125 mg/L, four times daily, 7 days). Indigenous gut microbiota, C. difficile total viable counts, spores, cytotoxin and antimicrobial activity in planktonic and biofilm communities were monitored during the 10 week experimental period.Vancomycin successfully treated the initial episode of simulated CDI, but ∼18 days after therapy cessation, recurrent infection occurred. Germination, proliferation and toxin production were evident within planktonic communities in both initial and recurrent CDI. In contrast, sessile C. difficile remained in dormant spore form for the duration of the experiment. The effects of and recovery from clindamycin and vancomycin exposure for sessile populations was delayed compared with responses for planktonic bacteria.Intestinal biofilms provide a potential reservoir for C. difficile spore persistence, possibly facilitating their dispersal into the gut lumen after therapeutic intervention, leading to recurrent infection. Therapeutic options for CDI could have increased efficacy if they are more effective against sessile C. difficile.
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- 2014
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11. Playing in the Past: A History of Games, Toys, and Puzzles in North American Libraries
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Scott Nicholson
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Service (business) ,Moral development ,Library services ,ComputingMilieux_PERSONALCOMPUTING ,Great Depression ,Library science ,Sociology ,Library and Information Sciences ,Recreation ,GeneralLiterature_MISCELLANEOUS ,Library materials - Abstract
Games and other forms of play are used in today’s libraries to attract underserved patrons, to introduce patrons to other library resources and services, and to facilitate engagement between library patrons. While many perceive gaming as a new library service, gaming services have been part of librarianship since the nineteenth century through chess clubs. During the Great Depression, libraries supported patrons with puzzle contests and developed circulating toy and game collections. Academic libraries built game collections for research and classroom needs, while school libraries collected and facilitated educational games to aid teachers. Video games have been used in libraries to help patrons learn to use technology and to bring groups of patrons together to enjoy shared experiences. The goal of this article is to demonstrate the different ways in which libraries have used games, toys, and puzzles over the last 150 years through both collections and services.
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- 2013
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12. Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery
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Mark H. Wilcox, Simon D. Baines, Jane Freeman, Caroline H. Chilton, Scott Nicholson, and Grace S. Crowther
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Microbiology (medical) ,Time Factors ,Colony Count, Microbial ,Biology ,medicine.disease_cause ,Microbiology ,Spore germination ,medicine ,Microscopy, Phase-Contrast ,Pharmacology (medical) ,Spores, Bacterial ,Pharmacology ,Microbial Viability ,Clostridioides difficile ,fungi ,Oritavancin ,Glycopeptides ,Lipoglycopeptides ,Clostridium difficile ,Anti-Bacterial Agents ,Spore ,Metronidazole ,Infectious Diseases ,Germination ,Staphylococcus aureus ,Vancomycin ,medicine.drug - Abstract
Previous work suggests oritavancin may be inhibitory to Clostridium difficile spores. We have evaluated the effects of oritavancin exposure on C. difficile spore germination, outgrowth and recovery.Germination and outgrowth of C. difficile spores exposed to different concentrations of oritavancin, vancomycin, or metronidazole (0.1-10 mg/L) were monitored at 0, 2, 4, 6, 24 and 48 h using phase-contrast microscopy. Recovery of antimicrobial-exposed spores was determined by viable counting on Brazier's modified CCEYL agar. Persistence of oritavancin activity on spores after washing was determined by measuring activity against a Staphylococcus aureus lawn.Oritavancin, vancomycin and metronidazole exposure did not prevent germination of phase-bright spores to phase-dark spores, but did inhibit further outgrowth into vegetative cells. The inhibitory effect of oritavancin persisted after washing, whereas the inhibitory effects of vancomycin and metronidazole did not. Oritavancin exposure affected spore recovery; fewer spores were recovered after washing following oritavancin exposure than vancomycin exposure. The extent of this effect was dependent on PCR ribotype, with recovery of ribotype 078 spores completely prevented, but recovery of ribotype 001 spores only slightly affected. Spores exposed to oritavancin, but not vancomycin, retained antimicrobial activity after washing, indicating adherence of oritavancin, but not vancomycin, to the spore surfaceOritavancin may adhere to spores, potentially causing early inhibition of germinated cells, preventing subsequent vegetative outgrowth and spore recovery. This may prevent some recurrences of symptomatic C. difficile infection that are due to germination of residual spores following antibiotic therapy.
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- 2013
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13. Introduction
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Scott Nicholson
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World Wide Web ,geography ,geography.geographical_feature_category ,Computer science ,Spring (hydrology) ,Library science ,General Medicine - Published
- 2013
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14. Three Different Paths for Tabletop Gaming in School Libraries
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Brenda Henderson, Scott Nicholson, Brian Mayer, and Teresa Copeland
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Game design ,General partnership ,ComputingMilieux_PERSONALCOMPUTING ,ComputingMilieux_COMPUTERSANDEDUCATION ,Library science ,Tesseract ,General Medicine ,Club ,School library ,Sociology ,Curriculum ,GeneralLiterature_MISCELLANEOUS ,School learning - Abstract
Three school library staff members explore how they have used tabletop games in different school library settings. Teresa Copeland (Tesseract School, Paradise Valley, Arizona, USA) explores how tabletop and role-playing games have been integrated into the curriculum across a wide variety of grade levels. Brenda Henderson (Trinity High School Learning Resources Centre, Redditch, UK) discusses how a board game club has made a difference in a high school library in the United Kingdom. Brian Mayer (School Library System, Genesee Valley Educational Partnership, LeRoy, New York, USA) supports multiple school libraries in finding matches between the curriculum and authentic games and runs game design workshops.
- Published
- 2013
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15. Go back to start: gathering baseline data about gaming in libraries
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Scott Nicholson
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World Wide Web ,Focus (computing) ,Phone ,Computer science ,Advertising ,Convenience sample ,Baseline data ,Library and Information Sciences ,Video game - Abstract
PurposeThe purpose of this paper is to develop some baseline data about games in libraries in North America. The term games is taken broadly in this piece to mean all types of games from card and board games to video games. The focus is primarily on public libraries, but there is some discussion of school and academic libraries as well.Design/methodology/approachThere were two surveys done. The first was a phone survey of 400 public libraries, selected at random. The second survey was a Web‐based convenience sample of libraries of different types. In both studies, we asked questions about the support of gaming in the library, the types of gaming programs run in the library, and the goals and outcomes of those gaming programs.FindingsAround 78 per cent of public libraries support gaming of some type. About 40 per cent run formal gaming programs, and about 20 per cent circulate games. The larger the library, the more likely they are to support gaming. The primary goals of gaming in libraries are to attract the underserved, attract current library patrons, and to create a space for social interactions between members of the community.Research limitations/implicationsThe first study is a random sample and therefore is a statistically significant representation of the population. The second study, being a Web‐based convenience sample, is not statistically representative of a population.Originality/valueThis type of baseline data is not available. Understanding how libraries are supporting games is valuable to researchers in asking appropriate questions. In addition, it helps libraries considering adding games to their services to learn how other libraries are doing it.
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- 2009
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16. How are libraries supporting gaming: A pilot exploration
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Scott Nicholson
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Engineering ,business.industry ,Library and Information Sciences ,business ,Information Systems - Published
- 2008
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17. Transforming data into services: Delivering the next generation of user-oriented collections and services
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Timothy J. Dickey, Scott Nicholson, Lynn Silipigni Connaway, Brian F. Lavoie, Julia A. Gammon, and Edward T. O'Neill
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World Wide Web ,Computer science ,Business sector ,Library classification ,User oriented ,Library and Information Sciences ,Data science ,Information Systems - Abstract
For decades, the corporate sector has exploited technological advances to better market and deliver products and services to customers via the techniques of data mining. The technique was not widely used in libraries. However, with the current emphasis on evidence-based decision making, libraries are beginning to utilize their system- and user- generated data. Data mining usually involves a significant endeavor to extract embedded and potentially useful information from large undiscovered data sets (Mitra & Acharya, 2003; Hand, Mannila & Smyth, 2001; Frawley, Piatetsky-Shapiro, & Matheus 1992; Piatetsky-Shapiro & Frawley 1991). These data mining techniques are being used by librarians to improve both internal decision-making and external user services by extracting information from operational datasets of both bibliographic and user data. OCLC Research has taken advantage of the WorldCat database, which includes more than 95 million bibliographic records and 1.2 billion holdings records, as well as data provided by other major library systems and consortia to develop user-oriented collections and services (http://www.oclc.org/research/projects/mining/).
- Published
- 2008
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18. Using context to improve data-based library evaluation through data warehousing, data mining and visualization
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Bob Molyneux, Lynn Silipigni Connaway, and Scott Nicholson
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Computer science ,Context (language use) ,Data mining ,Library and Information Sciences ,computer.software_genre ,Data science ,computer ,Data warehouse ,Information Systems ,Visualization - Published
- 2007
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19. The Digital Reference Electronic Warehouse Project
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Scott Nicholson and R. David Lankes
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World Wide Web ,Knowledge base ,business.industry ,Computer science ,Schema (psychology) ,Intermediation ,Information needs ,Library and Information Sciences ,Digital reference ,business ,Database transaction ,Information Systems - Abstract
One of the valuable offerings of librarians in the digital age is the human intermediation of information needs. In physical libraries, these reference questions are answered, and few artifacts remain from the transaction; therefore, the knowledge created through the work of the librarian leaves with the patron. Due to the medium of communication, digital reference transactions capture the knowledge of information professionals. There are hundreds of digital reference services generating knowledge every day; however, the lack of a schema for archiving reference transactions from multiple services makes it difficult to create a fielded, searchable knowledge base. The development of such a schema would allow researchers to develop tools that practitioners can employ. In turn, this would create a collaborative environment for digital reference evaluation. The goal of this work is to outline the steps needed to develop this schema, present the results of a survey of digital reference services, explore some of the pitfalls in the process, and envision the future uses of this Digital Reference Electronic Warehouse.
- Published
- 2007
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20. The basis for bibliomining: Frameworks for bringing together usage-based data mining and bibliometrics through data warehousing in digital library services
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Scott Nicholson
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Computer science ,Library services ,Subject (documents) ,Library and Information Sciences ,Management Science and Operations Research ,Bibliometrics ,computer.software_genre ,Digital library ,Data science ,Field (computer science) ,Data warehouse ,Electronic library ,Computer Science Applications ,World Wide Web ,Conceptual framework ,Media Technology ,Data mining ,computer ,Information Systems - Abstract
Over the past few years, data mining has moved from corporations to other organizations. This paper looks at the integration of data mining in digital library services. First, bibliomining, or the combination of bibliometrics and data mining techniques to understand library services, is defined and the concept explored. Second, the conceptual frameworks for bibliomining from the viewpoint of the library decision-maker and the library researcher are presented and compared. Finally, a research agenda to resolve many of the common bibliomining issues and to move the field forward in a mindful manner is developed. The result is not only a roadmap for understanding the integration of data mining in digital library services, but also a template for other cross-discipline data mining researchers to follow for systematic exploration in their own subject domains.
- Published
- 2006
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21. How much of it is real? Analysis of paid placement in Web search engine results
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Scott Nicholson, Tito Sierra, U. Yeliz Eseryel, Ji-Hong Park, Philip Barkow, Erika J. Pozo, and Jane Ward
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Human-Computer Interaction ,Artificial Intelligence ,Computer Networks and Communications ,Software ,Information Systems - Published
- 2006
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22. Digital Library Archaeology: A Conceptual Framework for Understanding Library Use through Artifact‐Based Evaluation
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Scott Nicholson
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business.industry ,Computer science ,Library services ,Artifact (software development) ,Library and Information Sciences ,Space (commercial competition) ,Bibliometrics ,Digital library ,Archaeology ,World Wide Web ,Web mining ,Conceptual framework ,The Internet ,business - Abstract
Archaeologists have used material artifacts found in a physical space to gain an understanding about the people who occupied that space. Likewise, as users wander through a digital library, they leave behind data‐based artifacts of their activity in the virtual space. Digital library archaeologists can gather these artifacts and employ inductive techniques, such as bibliomining, to create generalizations. These generalizations are the basis for hypotheses, which are tested to gain understanding about library services and users. In this article, the development of traditional archaeological methods is presented and used to create a conceptual framework for the artifact‐based evaluation in digital libraries.
- Published
- 2005
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23. Building Bridges for Collaborative Digital Reference between Libraries and Museums through an Examination of Reference in Special Collections
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Scott Nicholson, Kenneth Lavender, and Jeffrey Pomerantz
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Computer science ,business.industry ,Special collections ,Library science ,Library and Information Sciences ,Collections management ,Education ,World Wide Web ,Service information ,Digital human ,Question answering ,Intermediation ,The Internet ,Digital reference ,business - Abstract
While a growing number of the digital reference services in libraries have become part of collaborative reference networks, other entities that serve similar information-seeking needs such as special collections and museums have not joined these networks, even though they are answering an increasing number of questions from off-site patrons via the Internet. This article examines the differences between questions asked electronically of traditional reference services and those asked of special collections services; it further explores how a better understanding of digital reference in special collections will facilitate the development of the tools and models needed to create a bridge between digital human intermediation at general academic libraries, special collections, and museums.
- Published
- 2005
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24. A conceptual framework for the holistic measurement and cumulative evaluation of library services
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Scott Nicholson
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Engineering ,Knowledge management ,Computer science ,business.industry ,Library services ,media_common.quotation_subject ,Library and Information Sciences ,Digital library ,User studies ,Matrix (mathematics) ,Presentation ,Conceptual framework ,Systems theory ,Library management ,Library classification ,business ,Simulation ,Information Systems ,media_common - Abstract
This conceptual piece presents a framework to aid libraries in gaining a more thorough and holistic understanding of their users and services. Through a presentation of the history of library evaluation, a multidimensional matrix of measures is developed that demonstrates the relationship between the topics and perspectives of measurement. These measurements are then combined through evaluation criteria, and then different participants in the library system view those criteria for decision making. By implementing this framework for holistic measurement and cumulative evaluation, library evaluators can gain a more holistic knowledge of the library system and library administrators can be better informed for their decision‐making processes.
- Published
- 2004
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25. Digital Reference Triage: Factors Influencing Question Routing and Assignment
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Scott Nicholson, R. David Lankes, and Jeffrey Pomerantz
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World Wide Web ,Service (business) ,Process management ,Process (engineering) ,Information seeking ,Computer science ,Information system ,Delphi method ,Library and Information Sciences ,Routing (electronic design automation) ,Digital reference ,Triage - Abstract
This article describes a Delphi study conducted to determine factors that affect the process of routing and assigning reference questions received electronically by digital reference services, both to experts within the service and between services. Fifteen factors were determined, by expert consensus, to be important at the conclusion of this study. These fifteen factors are divided into three groups: (1) general factors, (2) factors when routing the question to an individual, and (3) factors when routing the question to another service. These factors were ranked in order of importance and grouped according to the recipient of the question. These fifteen factors need to be taken into account when automating the triage process. This article has laid out a methodology for investigating other digital reference processes so that those processes amenable to automation may be automated, and experts' talents and time may be best used.
- Published
- 2003
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26. Socialization in the 'virtual hallway'
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Scott Nicholson
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Multimedia ,Higher education ,Computer Networks and Communications ,business.industry ,Computer science ,Sense of community ,Distance education ,computer.software_genre ,Computer Science Applications ,Education ,Asynchronous learning ,Asynchronous communication ,ComputingMilieux_COMPUTERSANDEDUCATION ,Web application ,The Internet ,Computer-mediated communication ,business ,computer - Abstract
This research reports the findings from a survey that examined the differences in communication between students who used instant messenger (IM) services and those who did not in the same asynchronous distance education Web-based course. It was found that students who used IM services found it easier to communicate, felt a stronger sense of community, and had more venues for informal and social communication about not only class material, but also information about the school and their common degree program. In traditional classroom buildings, the common spaces such as hallways provide the venue for this informal communication; IM services can enhance the distance education environment by providing the “virtual hallways” for students and instructors to meet.
- Published
- 2002
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27. Recurrence of dual-strain Clostridium difficile infection in an in vitro human gut model
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Jane Freeman, Sharie L. Todhunter, Mark H. Wilcox, Grace S. Crowther, Scott Nicholson, and Caroline H. Chilton
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Microbiology (medical) ,medicine.drug_class ,Antibiotics ,Biology ,Gut flora ,Microbiology ,Recurrence ,Vancomycin ,medicine ,Humans ,Pharmacology (medical) ,Microbiome ,Feces ,Aged ,Pharmacology ,Aged, 80 and over ,Clostridioides difficile ,Clostridium difficile ,Middle Aged ,Models, Theoretical ,biology.organism_classification ,Antimicrobial ,Anti-Bacterial Agents ,Gastrointestinal Tract ,Infectious Diseases ,Treatment Outcome ,Immunology ,Ceftriaxone ,Clostridium Infections ,medicine.drug - Abstract
BackgroundClostridium difficile infection (CDI) is still a major challenge to healthcare facilities. The detection of multiple C. difficile strains has been reported in some patient samples during initial and recurrent CDI episodes. However, the behaviour of individual strains and their contribution to symptomatic disease is unclear.MethodsAn in vitro human gut model was used to investigate the germination and proliferation of two distinct C. difficile strains during initial and recurrent simulated CDI, as well as their response to vancomycin treatment. The gut model was inoculated with a pooled human faecal emulsion and indigenous gut microbiota, C. difficile populations (vegetative and spore forms), cytotoxin levels and antimicrobial activity were monitored throughout the experiment.ResultsBoth C. difficile strains germinated and proliferated in response to ceftriaxone instillation, with cytotoxin detected during the peak vegetative growth. Vancomycin instillation resulted in a rapid decline in the vegetative forms of both strains, with only spores remaining 2 days after the start of dosing. A recrudescence of both strains occurred following the cessation of vancomycin installation, although this was observed more quickly, and to a greater extent, in one strain than the other.ConclusionsWithin a human gut model, multiple C. difficile strains are able to germinate and proliferate concurrently in response to antibiotic challenge (the onset of simulated CDI). Similarly, more than one strain can proliferate during simulated recurrent CDI, although with differences in germination and growth rate and timing. It appears probable that multiple strains can contribute to CDI within an individual patient, with possible implications for management and bacterial transmission.
- Published
- 2014
28. A RECIPE for Meaningful Gamification
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Scott Nicholson
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Cognitive science ,Recipe ,Intrinsic motivation ,Context (language use) ,Meaning (existential) ,Psychology ,Exposition (narrative) - Abstract
Meaningful gamification is the use of gameful and playful layers to help a user find personal connections that motivate engagement with a specific context for long-term change. While reward-based gamification can be useful for short-term goals and situations where the participants have no personal connections or intrinsic motivation to engage in a context, rewards can reduce intrinsic motivation and the long-term desire to engage with the real world context. If the goal is long-term change, then rewards should be avoided and other game-based elements used to create a system based on concepts of meaningful gamification. This article introduces six concepts—Reflection, Exposition, Choice, Information, Play, and Engagement—to guide designers of gamification systems that rely on non-reward-based game elements to help people find personal connections and meaning in a real world context.
- Published
- 2014
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29. Efficacy of surotomycin in an in vitro gut model of Clostridium difficile infection
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Laurent Chesnel, Mark H. Wilcox, Scott Nicholson, Sharie L. Todhunter, Jane Freeman, Caroline H. Chilton, and Grace S. Crowther
- Subjects
Microbiology (medical) ,Surotomycin ,medicine.disease_cause ,Peptides, Cyclic ,Microbiology ,chemistry.chemical_compound ,Lipopeptides ,Clostridium ,medicine ,Humans ,Pharmacology (medical) ,Feces ,Pharmacology ,biology ,Toxin ,Clostridioides difficile ,Clindamycin ,Clostridium difficile ,Models, Theoretical ,biology.organism_classification ,Anti-Bacterial Agents ,Gastrointestinal Tract ,Infectious Diseases ,Treatment Outcome ,Enterococcus ,chemistry ,Clostridium Infections ,Bacteroides fragilis ,medicine.drug - Abstract
OBJECTIVES: We investigated the efficacy of the cyclic lipopeptide surotomycin in treating clindamycin-induced Clostridium difficile infection (CDI) using an in vitro gut model. METHODS: Two three-stage chemostat gut models were inoculated with human faeces, spiked with C. difficile spores (∼10(7) cfu/mL, PCR ribotype 027 or 001). Clindamycin (33.9 mg/L, four times daily for 7 days) was dosed to induce CDI. Following high-level toxin production, surotomycin (250 mg/L, twice daily for 7 days) was instilled. Microflora populations, C. difficile vegetative cells and spores, cytotoxin titres and antimicrobial levels (LC-MS/MS and bioassay) were determined. The emergence of C. difficile and enterococci with reduced susceptibility to surotomycin was monitored on breakpoint agar (4 × MIC). RESULTS: Counts of viable C. difficile were reduced to near the limit of detection on Days 1 and 3 of surotomycin instillation, and cytotoxin was undetectable on Days 3 and 4 of surotomycin instillation in the 027 and 001 models, respectively. Recurrence of vegetative growth and toxin production occurred 11 days (001 model) and 15 days (027 model) after surotomycin instillation had ceased, and remained for the duration of the experiment. Surotomycin instillation decreased populations of bifidobacteria, clostridia, enterococci and lactobacilli, but was sparing of Bacteroides fragilis group populations. All enumerated organisms had recovered to steady-state levels by 3 weeks post-surotomycin instillation. No evidence of the emergence of reduced susceptibility to surotomycin was observed. CONCLUSIONS: Surotomycin successfully reduced C. difficile vegetative cell counts and toxin levels in the gut model and was sparing of B. fragilis group populations. There was no evidence of decreased susceptibility to surotomycin during exposure or post-exposure.
- Published
- 2014
30. A Proposal for Categorization and Nomenclature for Web Search Tools
- Author
-
Scott Nicholson
- Subjects
medicine.medical_specialty ,Information retrieval ,Computer science ,business.industry ,Search engine indexing ,Semantic search ,Library and Information Sciences ,Terminology ,Web indexing ,World Wide Web ,Categorization ,Web mining ,medicine ,User interface ,business ,Web modeling - Abstract
SUMMARY Ambiguities in Web search tool (more commonly known as “search engine”) terminology are problematic when conducting precise, replicable research or when teaching others to use search tools. Standardized terminology would enable Web searchers to be aware of subtle differences between Web search tools and the implications of these for searching. A categorization and nomenclature for standardized classifications of different aspects of Web search tools is proposed, and advantages and disadvantages of using tools in each category are discussed.
- Published
- 2000
- Full Text
- View/download PDF
31. Successful treatment of simulated Clostridium difficile infection in a human gut model by fidaxomicin first line and after vancomycin or metronidazole failure
- Author
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Caroline H. Chilton, Jane Freeman, Scott Nicholson, Christopher Longshaw, Mark H. Wilcox, Grace S. Crowther, and Sharie L. Todhunter
- Subjects
Microbiology (medical) ,Microbial Sensitivity Tests ,Biology ,medicine.disease_cause ,Models, Biological ,Microbiology ,Vancomycin ,Metronidazole ,medicine ,Humans ,Pharmacology (medical) ,Fidaxomicin ,Treatment Failure ,Feces ,Pharmacology ,Toxin ,Clostridioides difficile ,Clindamycin ,Clostridium difficile ,Antimicrobial ,Gastrointestinal Tract ,Infectious Diseases ,Treatment Outcome ,Clostridium Infections ,Drug Therapy, Combination ,medicine.drug - Abstract
OBJECTIVES: Fidaxomicin reduces the risk of recurrent Clostridium difficile infection (CDI) compared with vancomycin. We investigated fidaxomicin primary or secondary treatment efficacy using a gut model. METHODS: Four triple-stage chemostat gut models were inoculated with faeces. After clindamycin induction of CDI, fidaxomicin (200 mg/L twice daily), vancomycin (125 mg/L four times daily) or metronidazole (9.3 mg/L three times daily) was administered for 7 days. Following failure/CDI recurrence, fidaxomicin (200 mg/L twice daily, 7 days) was instilled. C. difficile (CD) total viable counts (TVC), spore counts (SP), toxin titres (CYT), gut bacteria counts and antimicrobial concentrations were measured throughout. RESULTS: Fidaxomicin instillation reduced CD TVC/SP and CYT below the limit of detection (LOD) after 2 and 4 days, respectively, with no CDI recurrence. Metronidazole instillation failed to decrease CD TVC or CYT. Vancomycin instillation reduced CD TVC and CYT to LOD by day 4, but SP persisted. Recurrence occurred 13 days after vancomycin instillation; subsequent fidaxomicin instillation reduced CD TVC/SP/CYT below the LOD from day 2. CD was isolated sporadically, with no evidence of spore recrudescence or toxin production. Fidaxomicin had a minimal effect on the microflora, except for bifidobacteria. Fidaxomicin was detected for at least 21 days post-instillation, whereas other antimicrobials were undetectable beyond ∼4 days. CONCLUSIONS: Fidaxomicin successfully treated simulated primary and recurrent CDI. Fidaxomicin was superior to metronidazole in reducing CD TVC and SP, and superior to vancomycin in reducing SP without recurrence of vegetative cell growth. Fidaxomicin, but not vancomycin or metronidazole, persisted in the gut model for >20 days after instillation.
- Published
- 2013
32. Co-amoxiclav induces proliferation and cytotoxin production of Clostridium difficile ribotype 027 in a human gut model
- Author
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Scott Nicholson, Jane Freeman, Caroline H. Chilton, Sharie L. Todhunter, Mark H. Wilcox, and Grace S. Crowther
- Subjects
Microbiology (medical) ,genetic structures ,medicine.drug_class ,Antibiotics ,Bacterial Toxins ,Gut flora ,medicine.disease_cause ,Amoxicillin-Potassium Clavulanate Combination ,Ribotyping ,Microbiology ,Bacterial Proteins ,Bone plate ,medicine ,Bioassay ,Humans ,Pharmacology (medical) ,Aged ,Pharmacology ,Gastrointestinal tract ,Microbial Viability ,biology ,Virulence ,Toxin ,Clostridioides difficile ,Clostridium difficile ,Models, Theoretical ,biology.organism_classification ,Antimicrobial ,Bacterial Load ,Anti-Bacterial Agents ,Gastrointestinal Tract ,Infectious Diseases ,Immunology - Abstract
Objectives Co-amoxiclav is widely prescribed in hospitals. Although reports have suggested it may be linked to onset of Clostridium difficile infection (CDI), data on the risk of CDI associated with specific antibiotics is difficult to obtain, due to confounding clinical factors. We have examined the propensity of co-amoxiclav to induce CDI using a human gut model. Methods We used a triple-stage chemostat human gut model to study the effects of co-amoxiclav on indigenous gut microorganisms and C. difficile PCR ribotype 027. C. difficile viable counts and spores were evaluated, and cytotoxin titres were assayed. Co-amoxiclav concentrations were measured using a large plate bioassay. Results Co-amoxiclav induced rapid C. difficile germination and high toxin production in the gut model, from 5 days after commencement of instillation. Cell proliferation and toxin production were prolonged and continued throughout the duration of the experiment. Only very low levels of co-amoxiclav antimicrobial activity could be detected within the gut model, despite having a marked effect on gut flora microorganisms. Conclusions Co-amoxiclav induced CDI within the gut model, supporting clinical observations linking co-amoxiclav treatment with CDI onset. This reinforces the value of the gut model as a clinically relevant means of studying CDI. Caution should be exercised in the prescription of co-amoxiclav to patients in high CDI risk settings.
- Published
- 2012
33. Gaining Strategic Advantage Through Bibliomining
- Author
-
Jeffrey M. Stanton and Scott Nicholson
- Subjects
Information privacy ,Knowledge management ,business.industry ,Computer science ,Data management ,Information ethics ,Strategic advantage ,Data mining ,business ,computer.software_genre ,Data science ,computer ,Data warehouse - Abstract
Library and information services in corporations, schools, universities and communities capture information about their users, circulation history, resources in the collection and search patterns (Koenig, 1985). Unfortunately, few libraries have taken advantage of these data as a way to improve customer service, manage acquisition budgets or influence strategic decision making about uses of information in their organizations. In this chapter, we present a global view of the data generated in libraries, and the variety of decisions that those data can inform. We describe ways in which library and information managers can use data mining in their libraries, i.e., bibliomining, to understand patterns of behavior among library users and staff members and patterns of information resource use throughout the institution. The chapter examines data sources and possible applications of data mining techniques in the library.
- Published
- 2011
- Full Text
- View/download PDF
34. Connections for game education and research in the iSchools
- Author
-
Scott Nicholson
- Subjects
Game mechanics ,Knowledge management ,Game design document ,business.industry ,ComputingMilieux_PERSONALCOMPUTING ,Game research ,Information science ,Game design ,Order (business) ,Political science ,ComputingMilieux_COMPUTERSANDEDUCATION ,Mathematics education ,Video game design ,Game Developer ,business - Abstract
There is a growing level of interest in games in the iSchools. Some schools are teaching courses focused on the creation of games, while others schools have researchers exploring game topics. In order to engage with game programs and researchers from outside the iSchools, it is important to understand the different areas of game education and research, and how concepts from information science can be used to advance game research.
- Published
- 2011
- Full Text
- View/download PDF
35. Improved Drilling Performance and Economics Using Hybrid Coiled Tubing Unit on the Chittim Ranch, West Texas
- Author
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Curtis G. Blount, Scott Nicholson, and Brady Louis Littleton
- Subjects
Coiled tubing ,Engineering ,Petroleum engineering ,business.industry ,Drilling ,business ,Unit (housing) - Abstract
A significant performance and cost improvement was achieved with the application of hybrid Coiled Tubing (CT) drilling equipment and techniques on the Chittim Ranch in Maverick county Texas. During this drilling program, 233 wells were grass-root drilled using the hybrid CT unit. Coiled tubing drilling equipment and techniques reduced the average time to complete a well by 60% when compared to conventional rotary rig drilling. This increase in drilling performance coupled with a turnkey contract resulted in a 14% (33% adjusted for inflation) cost reduction per well when compared to the most recent conventional drilling data from this area. This paper will review the process used in choosing a CT solution, the hurdles overcome, the problems encountered, and the lessons learned in managing and operating this CT Drilling (CTD) campaign. The paper will also provide an overview of CT coring performed in one of the wells during the CTD campaign. The drilling performance increase was realized using a top-set rig to set surface casing and a hybrid "Big Wheel" CT rig to drill the production hole. Finalized project data demonstrated that field performance using CTD met and in some areas exceeded project goals.
- Published
- 2010
- Full Text
- View/download PDF
36. Bibliomining for Library Decision-Making
- Author
-
Scott Nicholson
- Abstract
Most people think of a library as the little brick building in the heart of their community or the big brick building in the center of a college campus. However, these notions greatly oversimplify the world of libraries. Most large commercial organizations have dedicated in-house library operations, as do schools; nongovernmental organizations; and local, state, and federal governments. With the increasing use of the World Wide Web, digital libraries have burgeoned, serving a huge variety of different user audiences. With this expanded view of libraries, two key insights arise. First, libraries are typically embedded within larger institutions. Corporate libraries serve their corporations, academic libraries serve their universities, and public libraries serve taxpaying communities who elect overseeing representatives. Second, libraries play a pivotal role within their institutions as repositories and providers of information resources. In the provider role, libraries represent in microcosm the intellectual and learning activities of the people who comprise the institution. This fact provides the basis for the strategic importance of library data mining: By ascertaining what users are seeking, bibliomining can reveal insights that have meaning in the context of the library’s host institution. Use of data mining to examine library data might be aptly termed bibliomining. With widespread adoption of computerized catalogs and search facilities over the past quarter century, library and information scientists have often used bibliometric methods (e.g., the discovery of patterns in authorship and citation within a field) to explore patterns in bibliographic information. During the same period, various researchers have developed and tested data-mining techniques, which are advanced statistical and visualization methods to locate nontrivial patterns in large datasets. Bibliomining refers to the use of these bibliometric and data-mining techniques to explore the enormous quantities of data generated by the typical automated library.
- Published
- 2009
- Full Text
- View/download PDF
37. Gaining Strategic Advantage Through Bibliomining
- Author
-
Scott Nicholson and Jeffrey Stanton
- Abstract
Library and information services in corporations, schools, universities and communities capture information about their users, circulation history, resources in the collection and search patterns (Koenig, 1985). Unfortunately, few libraries have taken advantage of these data as a way to improve customer service, manage acquisition budgets or influence strategic decision making about uses of information in their organizations. In this chapter, we present a global view of the data generated in libraries, and the variety of decisions that those data can inform. We describe ways in which library and information managers can use data mining in their libraries, i.e., bibliomining, to understand patterns of behavior among library users and staff members and patterns of information resource use throughout the institution. The chapter examines data sources and possible applications of data mining techniques in the library.
- Published
- 2008
- Full Text
- View/download PDF
38. The Effects of Choice Context on Decision-Making: An Application to Voter Fatigue
- Author
-
Scott Nicholson
- Subjects
Natural experiment ,Ballot ,Spoilt vote ,Public economics ,Political science ,General election ,Context (language use) ,Exhaustive ballot ,CONTEST ,Voter fatigue - Abstract
This paper exploits a natural experiment in which choice fatigue is isolated as an explanation for the usage of heuristics in decision-making. The em- pirical application provides evidence that voters who see a given contest relatively further down the ballot are more likely to vote "no" and to abstain. Within-election exogenous variation in ballot position is primarily due to differences in the set of overlaying local political jurisdictions. My central finding is that lowering a proposi- tion 10 positions on the ballot increases precinct-level "no" votes and undervotes by 1.3 and 0.7 percentage points, respectively. Interestingly, 8 of 124 statewide propo- sitions in the dataset have winning margins within the range of the "no" estimate. The empirical analysis employs a unique precinct-level panel dataset of votes cast for the entire menu of federal, state & local ballot choices in primary and general elections between 1992 and 2006 in San Diego County, California. Implications of the results range from the dissemination of information by firms and policy makers to the design of electoral institutions and the strategic use of ballot propositions.
- Published
- 2007
- Full Text
- View/download PDF
39. Using lessons from health care to protect the privacy of library users: Guidelines for the de-identification of library data based on HIPAA
- Author
-
Scott Nicholson, Catherine Arnott Smith, and Grove, Andrew
- Subjects
Computer Networks and Communications ,business.industry ,Computer science ,Health Insurance Portability and Accountability Act ,Privacy policy ,De-identification ,ComputingMilieux_LEGALASPECTSOFCOMPUTING ,Library and Information Sciences ,Computer security ,computer.software_genre ,Data warehouse ,Human-Computer Interaction ,Work (electrical) ,Artificial Intelligence ,Health care ,BF. Information policy ,business ,computer ,Parallels ,Software ,Information Systems ,Protected health information - Abstract
While libraries have employed policies to protect the data about use of their services, these policies are rarely specific or standardized. Since 1996 the U.S. healthcare system has been grappling with the Health Insurance Portability and Accountability Act (HIPAA), which is designed to provide those handling personal health information with standardized, definitive instructions as to the protection of data. In this work, the authors briefly discuss the present situation of privacy policies about library use data, outline the HIPAA guidelines to understand parallels between the two, and finally propose methods to create a de-identified library data warehouse based on HIPAA for the protection of user privacy.
- Published
- 2006
- Full Text
- View/download PDF
40. Creating the infrastructure for collaboration between digital reference services and researchers
- Author
-
R. David Lankes and Scott Nicholson
- Subjects
World Wide Web ,Management information systems ,Standardization ,Library management ,computer.internet_protocol ,Computer science ,Schema (psychology) ,Digital reference ,Digital library ,computer ,XML ,Data warehouse - Abstract
The Digital Reference Electronic Warehouse (DREW) project is a collection of digital reference transactions from different services and different communication channels that live in a single space. Reference services work with DREW to submit transactions using the DREW schema, which is conceptually similar to the MARC record format for bibliographic materials. Researchers can then receive records from DREW to improve our knowledge of digital reference. These researchers then use the results of their research to create tools, reports, and models based on the DREW schema, and place those items into a management information system (MIS). The services can then access the MIS and apply those tools to their own archives. The result is that services can benefit directly and rapidly from research, and are then more likely to continue their involvement with the project. This infrastructure creates a collaborative space where researchers and practitioners can benefit from the work of each other and aid us in advancing the field of digital reference.
- Published
- 2005
- Full Text
- View/download PDF
41. A framework for Internet archeology: Discovering use patterns in digital library and Web–based information resources
- Author
-
Scott Nicholson
- Subjects
Computer Networks and Communications ,business.industry ,Computer science ,Bibliometrics ,Digital library ,Data science ,Archaeology ,Data warehouse ,Information science ,Human-Computer Interaction ,World Wide Web ,Information space ,Information system ,Web application ,The Internet ,business - Abstract
Archeologists use artifacts to make statements about occupants of a physical space. Users of information resources leave behind data–based artifacts when they interact with a digital library or other Web–based information space. One process for examining these patterns is bibliomining, or the combination of data warehousing, data mining and bibliometrics to understand connections and patterns between works. The purpose of this paper is to use a research framework from archeology to structure exploration of these data artifacts through bibliomining to aid managers of digital libraries and other Web–based information resources.
- Published
- 2005
- Full Text
- View/download PDF
42. Bibliomining for Library Decision-Making
- Author
-
Jeffrey M. Stanton and Scott Nicholson
- Subjects
business.industry ,media_common.quotation_subject ,Institution ,The Internet ,Context (language use) ,Public relations ,Bibliometrics ,business ,Digital library ,Data warehouse ,Meaning (linguistics) ,media_common ,Variety (cybernetics) - Abstract
Most people think of a library as the little brick building in the heart of their community or the big brick building in the center of a campus. These notions greatly oversimplify the world of libraries, however. Most large commercial organizations have dedicated in-house library operations, as do schools, non-gov-ernmental organizations, as well as local, state, and federal governments. With the increasing use of the Internet and the World Wide Web, digital libraries have burgeoned, and these serve a huge variety of different user audiences. With this ex-panded view of libraries, two key insights arise. First, libraries are typically embedded within larger institutions. Corporate libraries serve their corporations, academic libraries serve their universities, and public libraries serve taxpaying communities who elect overseeing representatives. Second, libraries play a pivotal role within their institutions as repositories and pro-viders of information resources. In the provider role, libraries represent in microcosm the intellectual and learning activities of the people who comprise the institution. This fact provides the basis for the strategic importance of library data mining: By ascertaining what users are seeking, bibliomining can reveal insights that have meaning in the context of the library’s host institution.Use of data mining to examine library data might be aptly termed
- Published
- 2005
- Full Text
- View/download PDF
43. Bibliomining for Library Decision-Making
- Author
-
Scott Nicholson and Jeffrey Stanton
- Abstract
Most people think of a library as the little brick building in the heart of their community or the big brick building in the center of a campus. These notions greatly oversimplify the world of libraries, however. Most large commercial organizations have dedicated in-house library operations, as do schools, non-governmental organizations, as well as local, state, and federal governments. With the increasing use of the Internet and the World Wide Web, digital libraries have burgeoned, and these serve a huge variety of different user audiences. With this expanded view of libraries, two key insights arise. First, libraries are typically embedded within larger institutions. Corporate libraries serve their corporations, academic libraries serve their universities, and public libraries serve taxpaying communities who elect overseeing representatives. Second, libraries play a pivotal role within their institutions as repositories and providers of information resources. In the provider role, libraries represent in microcosm the intellectual and learning activities of the people who comprise the institution. This fact provides the basis for the strategic importance of library data mining: By ascertaining what users are seeking, bibliomining can reveal insights that have meaning in the context of the library’s host institution. Use of data mining to examine library data might be aptly termed bibliomining. With widespread adoption of computerized catalogs and search facilities over the past quarter century, library and information scientists have often used bibliometric methods (e.g., the discovery of patterns in authorship and citation within a field) to explore patterns in bibliographic information. During the same period, various researchers have developed and tested data mining techniques—advanced statistical and visualization methods to locate non-trivial patterns in large data sets. Bibliomining refers to the use of these bibliometric and data mining techniques to explore the enormous quantities of data generated by the typical automated library.
- Published
- 2005
- Full Text
- View/download PDF
44. Aluminum: A potential pro-oxidant in sunscreens/sunblocks?
- Author
-
Christopher Exley and Scott Nicholson
- Subjects
medicine.medical_specialty ,Chemistry ,Skin Absorption ,Melanoma ,Oxidants ,Pro-oxidant ,medicine.disease ,Biochemistry ,Dermatology ,Oxidative Stress ,Physiology (medical) ,medicine ,Cancer research ,Humans ,Skin cancer ,Sunscreening Agents ,Aluminum - Published
- 2007
- Full Text
- View/download PDF
45. The bibliomining process: Data warehousing and data mining for libraries. Sponsored by SIG LT
- Author
-
Scott Nicholson, San-Yih Hwang, Edward T. O'Neill, and Paula Keezer
- Subjects
Computer science ,Process (engineering) ,InformationSystems_DATABASEMANAGEMENT ,Library and Information Sciences ,Bibliometrics ,computer.software_genre ,Data science ,Data warehouse ,Metadata ,Identification (information) ,Library classification ,Data mining ,computer ,Information Systems - Abstract
Bibliomining is the combination of data mining, bibliometrics, statistics, and reporting tools used to extract patterns of behavior-based artifacts and item-based metadata from library systems. The bibliomining process involves the identification of problem areas, the collecting and anonymizing of data into a data warehouse, the exploration of the data with data mining tools, and the analysis, validation, and implementation of the results. This panel will introduce the topic of bibliomining and present ways in which data warehousing and data mining are currently being used in library settings.
- Published
- 2005
- Full Text
- View/download PDF
46. Models for library management, decision-making, and planning
- Author
-
Scott Nicholson
- Subjects
Human-Computer Interaction ,Engineering ,Library management ,Artificial Intelligence ,Computer Networks and Communications ,business.industry ,Library science ,business ,Software ,Information Systems - Published
- 2003
- Full Text
- View/download PDF
47. A Perspective on Wigner's 'Unreasonable Effectiveness of Mathematics'
- Author
-
Jason Scott Nicholson
- Subjects
General Mathematics - Published
- 2012
- Full Text
- View/download PDF
48. A Framework for Technology Selection in a Web-Based Distance Education Environment: Supporting Community-Building through Richer Interaction Opportunities
- Author
-
Scott Nicholson
- Subjects
Community building ,business.industry ,media_common.quotation_subject ,Sense of community ,Distance education ,Library science ,Library and Information Sciences ,Public relations ,Education ,Social group ,Information and Communications Technology ,ComputingMilieux_COMPUTERSANDEDUCATION ,Institution ,Web application ,Sociology ,Computer-mediated communication ,business ,media_common - Abstract
Librarianship, as a profession, relies upon a strong network of colleagues outside the institution for collaboration. The seeds for this collaborative culture are planted in library school; however, in an online environment the challenges are greater when creating that sense of community. By supporting more ways to allow students, faculty, staff, and alumni to communicate in a distance education environment, the sense of community of the school can be raised. This community building can be done either within the confines of a course (internal) or outside the course structure (external). In both cases, the concept is the same - develop more pathways through a communication scaffold that allow individuals who are part of the community of the school to connect. There are three dimensions to consider in developing this scaffold: Synchronous vs. Asynchronous; Facilitated vs. Non-Facilitated; and 1-way vs. 2-way. By being conscious of these choices, those working to improve interaction can try to incorporate different types of experiences in order to encourage a larger group of people to participate.
- Published
- 2005
- Full Text
- View/download PDF
49. Wrangling over the Bang
- Author
-
Robert E. McDaniel, James Hartley, Anthony L. Peratt, Scott Nicholson, Halton Arp, Eric J. Lerner, William E. White, Tom Paskal, Robert Herman, M. E. Renshaw, Paul A. Daugherty, and Tom Mandel
- Subjects
General Engineering - Published
- 1991
- Full Text
- View/download PDF
50. AIDS before the '80s
- Author
-
Scott Nicholson
- Subjects
medicine.medical_specialty ,Acquired immunodeficiency syndrome (AIDS) ,Family medicine ,General Engineering ,medicine ,medicine.disease - Published
- 1988
- Full Text
- View/download PDF
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