1. Salvia officinalis L. Esansiyel Yağının Antimikrobiyal ve Antioksidan Aktivite Potansiyelinin Değerlendirilmesi.
- Author
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ÖZÇOBAN, Afranur and GEDİKOĞLU, Ayça
- Subjects
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DISC diffusion tests (Microbiology) , *ESSENTIAL oils , *SAGE , *SALMONELLA typhimurium , *ENTEROCOCCUS faecalis , *BACILLUS cereus - Abstract
This study set out to determine the effects of Salvia officinalis L., commonly known as sage, on the chemical composition of the essential oil, its free radical scavenging activity (IC50), ferric-reducing antioxidant power (FRAP) value, and antimicrobial properties. According to the results of the GC-MS analysis, 3-thujen-2-one, (26,21%), (+)-2-bornanone (16.47%), and 1,8-cineole (15.09%) were the compounds with the highest percentage in the sage essential oil. In addition, the essential oil showed high antioxidant activity, providing an IC50 value of 5.507 ± 0.723 mg/ml and a FRAP value of 2.129 ± 0.136 mM/g. The findings of the agar disc diffusion test demonstrated that the highest inhibition zones were against Bacillus cereus NRRL B3711 and Bacillus subtilis PY79 bacteria, whereas the lowest antimicrobial effect was shown against Listeria monocytogenes ATCC 19115 and Escherichia coli ATCC 25922. Similarly, sage essential oil showed the highest antimicrobial effect in the broth dilution test with a minimum inhibitory concentration (MIC) value of 2.94 mg/ml against Bacillus cereus NRRL B3711, while its effectiveness against Staphylococcus spp., Enterococcus faecalis ATCC 29212, and Salmonella typhimurium ATCC 14028 bacteria was the lowest with a MIC value of 23.5 mg/ml. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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