1. Amperometric Biosensor and Front-End Electronics for Remote Glucose Monitoring by Crosslinked PEDOT-Glucose Oxidase.
- Author
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Aleeva, Yana, Maira, Giovanni, Scopelliti, Michelangelo, Vinciguerra, Vincenzo, Scandurra, Graziella, Cannata, Gianluca, Giusi, Gino, Ciofi, Carmine, Figa, Viviana, Occhipinti, Luigi G., and Pignataro, Bruno Giuseppe
- Abstract
Focusing on the interplay between interface chemistry, electrochemistry, and integrated electronics, we show a novel low-cost and flexible biosensing platform for continuous glucose monitoring. The amperometric biosensing system features a planar three-electrode structure on a plastic substrate, and a wireless near-field communication-powered electronic system performing sensor analog front-end, A/D conversion, digital control, and display tasks. The working electrode is made of electropolymerized poly (3,4-ethylenedioxythiophene) film onto a polyethylene terephthalate/gold electrode followed by immobilization of cross-linked glucose oxidase by glutaraldehyde. The advantages offered by such a device, including low-cost materials and instrumentation as well as the good sensitivity of 9.24 \mu \textA/(\mathrm mM \cdot \mathrm cm^2) are promising tools for point-of-care monitoring. It is demonstrated that the devices are good candidates for the development of advanced sensing approaches based on the investigation of the noise produced during operation (fluctuation-enhanced sensing). [ABSTRACT FROM PUBLISHER]
- Published
- 2018
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