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Amperometric Biosensor and Front-End Electronics for Remote Glucose Monitoring by Crosslinked PEDOT-Glucose Oxidase.
- Source :
- IEEE Sensors Journal; 6/15/2018, Vol. 18 Issue 12, p4869-4878, 10p
- Publication Year :
- 2018
-
Abstract
- Focusing on the interplay between interface chemistry, electrochemistry, and integrated electronics, we show a novel low-cost and flexible biosensing platform for continuous glucose monitoring. The amperometric biosensing system features a planar three-electrode structure on a plastic substrate, and a wireless near-field communication-powered electronic system performing sensor analog front-end, A/D conversion, digital control, and display tasks. The working electrode is made of electropolymerized poly (3,4-ethylenedioxythiophene) film onto a polyethylene terephthalate/gold electrode followed by immobilization of cross-linked glucose oxidase by glutaraldehyde. The advantages offered by such a device, including low-cost materials and instrumentation as well as the good sensitivity of 9.24 \mu \textA/(\mathrm mM \cdot \mathrm cm^2) are promising tools for point-of-care monitoring. It is demonstrated that the devices are good candidates for the development of advanced sensing approaches based on the investigation of the noise produced during operation (fluctuation-enhanced sensing). [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 1530437X
- Volume :
- 18
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- IEEE Sensors Journal
- Publication Type :
- Academic Journal
- Accession number :
- 129840695
- Full Text :
- https://doi.org/10.1109/JSEN.2018.2831779