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We develop a method to use the mixed third and second harmonic electron cyclotron emission (ECE) signal in the DIII-D tokamak to reconstruct the electron temperature profile of a rotating magnetic island. The third harmonic ECE is removed by extracting the rotating-island-associated fluctuations in the mixed signal, and the extracted fluctuation is combined with the equilibrium temperature obtained from other diagnostics after correcting for the third harmonic reabsorption. The accuracy of the reconstruction is studied by considering a DIII-D shot where an unmixed signal from an island is available on the low field side of the plasma and a mixed signal from the same island is available from the high field side. It is found that the reconstruction method successfully reproduces the island shape and temperature perturbation magnitude without the distortion caused by third harmonic ECE mixing. However, the radial location of the reconstructed island is somewhat displaced relative to the location of the q = 2 surface in the axisymmetric equilibrium reconstruction, resulting in a corresponding inaccuracy in the absolute temperature of the island. It is conjectured that this may arise from an inaccuracy of the reconstructed axisymmetric equilibrium in this region. [ABSTRACT FROM AUTHOR]

We present a highly efficient algorithm for computing the minimum distance between two solids of revolution, each of which is defined by a planar cross‐section region and a rotation axis. The boundary profile curve for the cross‐section is first approximated by a bounding volume hierarchy (BVH) of fat arcs. By rotating the fat arcs around the axis, we generate the BVH of fat tori that bounds the surface of revolution. The minimum distance between two solids of revolution is then computed very efficiently using the distance between fat tori, which can be boiled down to the minimum distance computation for circles in the three‐dimensional space. Our circle‐based approach to the solids of revolution has distinctive features of geometric simplification. The main advantage is in the effectiveness of our approach in handling the complex cases where the minimum distance is obtained in non‐convex regions of the solids under consideration. Though we are dealing with a geometric problem for solids, the algorithm actually works in a computational style similar to that of handling planar curves. Compared with conventional BVH‐based methods, our algorithm demonstrates outperformance in computing speed, often 10–100 times faster. Moreover, the minimum distance can be computed very efficiently for the solids of revolution under deformation, where the dynamic reconstruction of fat arcs dominates the overall computation time and takes a few milliseconds. [ABSTRACT FROM AUTHOR]

Ne–Kr gas mixtures with high Kr concentrations were applied to ac plasma display panels. Spatiotemporal behaviors of excited Kr atoms in the 1s5 metastable state and the 1s4 resonance state were measured by microscopic laser-absorption spectroscopy in the binary mixtures with Kr concentrations of 20% and 40%. A systematic comparison was done between the characteristics of Ne–Kr-filled panels and those of conventional Ne–Xe panels with the same structure but with lower Xe concentrations of 5% and 10%. For example, the total number of Kr*(1s5) atoms in a unit cell ranged from 7.4×107 to 2.0×108, at the peak was apparently smaller than the value of Xe*(1s5) atoms. However, when the difference in the decay rate of the excited atoms by three-body collision processes is taken into account, the production efficiency of vacuum-ultraviolet (VUV) emission from Kr2* excimers is as large as that from Xe2* excimers in a usual panel since these processes lead directly to the formation of excimers. From the measured density of Kr*(1s4) atoms, it is estimated that the contribution of the atomic resonance line is smaller than the excimer band at those high Kr concentrations. In any case, by summing up those two contributions to the VUV emission, the overall efficiency in the Ne–Kr(40%) panel is estimated to be comparable to that in the Ne–Xe(10%) one. [ABSTRACT FROM AUTHOR]

A quantum dot transistors (QDT) and a nanowire transistor from a metal-semiconductor field-effect-transistors (MESFET)-type GaAs wafer was fabricated and characterized at low temperatures. The nanodevices showed a quantum mechanical effect like scanning electron microscope (SET) through excited states and negative differentail resistance (NDR).

Byline: S.-J. Heo, K. Park, S.-H. Son The continuously variable damper is widely used in the semi-active suspension system since it can yield various damping forces at a given damper velocity. By applying an appropriate control scheme to the damper, satisfaction of both ride comfort and driving safety can be realised. For successful development of the semi-active suspension system, a model that accurately describes the complex and nonlinear behaviour of the continuously variable damper is crucial. In this research, a modelling technique for the continuously variable damper has been studied. Various damper components have been analysed and their effects upon damper characteristics have been closely investigated. The effects of the damper characteristics change upon ride comfort and driving safety have also been investigated via simulations.

The temperature influence of the matching liquid used in the microwave tomography platform system working from 3 to 6 GHz was analyzed on the article. The temperature impact of the matching liquid was found using the measured signal data. If the temperature of the matching liquid is maintained ideally, the measured signal data are obtained the stable data. But, the acquired signal data are obtained the unstable data because the temperature of matching liquid can not be maintained naturally. To obtain the stable data, the temperature control devices are required to maintain the temperature of matching liquid. Furthermore, the temperature variation of the matching liquid in the platform system is the important factor aimed for breast cancer detection. How much impact happened by the temperature variation was studied to overcome the temperature influence of the matching liquid. © 2014 Wiley Periodicals, Inc. Microwave Opt Technol Lett 56:2978-2981, 2014 [ABSTRACT FROM AUTHOR]

A new form of doxorubicin hydrochloride (DRH)-containing chitosan microspheres (CMs) was prepared by employing an expanding-loading-shrinking (E-L-S) process. One hundred mg of pre-formed CMs were soaked in absolute ethanol and then placed in reduced pressure (the expanding process). Ten mg of DRH (2 mg ml-1) were added into the expanded CMs (the loading process). Next the microspheres were freeze-dried (the shrinking process). As a result of this E-L-S process, 10% (w/w) DRH-containing CMs (DRH-CM) were made. During 7 days, 22.6% of the DRH was observed to be released on the in vitro drug release study. In addition, these new DRH-CMs could be used for transcatheter arterial chemoembolization (TACE) procedure in VX2 hepatic tumour models of rabbit and the anti-tumour effects of DRH-CMs were investigated. On the post-CT scan 7 days after the TACE, total infarctions of the VX2 tumour were observed in 5 rabbits among the 6 total rabbits. [ABSTRACT FROM AUTHOR]

The article offers information on focused microwave thermotherapy (FMT) which is a noninvasive microwave hyperthermia to increase the temperature of the target location to above 43°C while maintaining a normal temperature in other areas. It presents information on electromagnetic (EM) wave propagation. It mentions information on dielectric map which is created from magnetic resonance imaging or computer tomography.

Craniospinal irradiation (CSI) is the standard treatment of primary intracranial tumour with risk of leptomeningeal dissemination. However, supine setup field-in-field technique does not need inter-fractional junction shift. Recently, the studies of CSI with tomotherapy showed excellent target coverage and tolerable normal organ dose in paediatric patients. The planning comparison and dosimetric difference between conventional radiotherapy and tomotherapy are presented. Three patients with central nervous system germinoma received supine CSI treatment. Normal tissue complication probability calculation was performed for parotid gland, kidney, lens, small bowel, ovary and testis. Homogenous vertebral body coverage for tomotherapy compared with conformal radiotherapy was found. The mean dose to each parotid gland decreased by 7.3 and 10 Gy, respectively, with tomotherapy. The volume of oesophagus and small bowel receiving >10 Gy was significantly lower. The V2, V5, V10 and V20 of the lungs are 81.6, 12.4, 2.3 and 0 % with tomotherapy. Tomotherapy showed excellent homogenous dose distribution through the craniospinal axis (PTV) and higher conformity index. [ABSTRACT FROM PUBLISHER]

The thermal expansion and magnetostriction of polycrystalline and single-crystal Pr5 Ni2 Si3 were investigated over the temperature range 5-300 K. The results show two magnetic phase transitions, one corresponding to the Curie temperature and the other at a lower temperature exhibiting characteristics of a spin reorientation transition. In the temperature range below the Curie temperature, the thermal expansion in single-crystal samples exhibited a temperature dependent anisotropy. Specifically negative and positive magnetic contributions to the thermal expansion were observed along the directions parallel and perpendicular to the c axis respectively. [ABSTRACT FROM AUTHOR]

In this article, we report a new 3-D backlight display for glasses-free 2-D/3-D switchable displays. In this type of 3-D display, 3-D works by line patterned back light unit. But light leakages from the 3-D light guide cause degrade the 3-D performance. We analyze the light leakages from light guide plate and suggest a novel backlight structure design to improve x-talk performance. [ABSTRACT FROM AUTHOR]

This letter reports on an improved forward voltage drop (V[sub F]) and reverse leakage current (I[sub R]) in Schottky barrier rectifier using vanadium (V–SBR) as the barrier metal with a low barrier height (&fgr;[sub B]) and argon implantation. The V[sub F] for a V–SBR was as low as 0.25 V compared to 0.39 V for a molybdenum (Mo)–SBR at the same forward current density (J[sub F]) of 60 A/cm[sup 2]. This study was able to achieve a good result for J[sub F] in SBR. Presently, the conventional Schottky rectifier with a low &fgr;[sub B] metal is used to achieve low V[sub F], but at the expense of a high I[sub R]. To reduce this effect, crystalline Si was altered into amorphous Si using argon implantation on the n-epitaxial layer. Finally, a SBR with a high J[sub F] and low I[sub R] could be fabricated. © 2001 American Institute of Physics. [ABSTRACT FROM AUTHOR]

Importance: Several studies have suggested that endoplasmic reticulum (ER) stress is important in the pathogenesis of infectious diseases; however, the precise function of ER stress regulation and the role of Herp as a regulator in Mtb H37Ra-induced ER stress remain elusive. Therefore, our study investigated ER stress and autophagy associated with Herp expression in Mycobacterium tuberculosis -infected macrophages to determine the role of Herp in the pathogenesis of tuberculosis., Competing Interests: The authors declare no conflict of interest.

Objective: To evaluate the accuracy of pencil beam calculation (PBC) and Monte Carlo calculation (MCC) for dynamic arc therapy (DAT) in a cylindrically shaped homogenous phantom, by comparing the two plans with an ion chamber, a film and a three-dimensional (3D) volumetric dosemeter., Methods: For this study, an in-house phantom was constructed, and the PBC and MCC plans for DAT were performed using iPlan® RT (BrainLAB®, Heimstetten, Germany). The A16 micro ion chamber (Standard Imaging, Middleton, WI), Gafchromic® EBT2 film (International Specialty Products, Wayne, NJ) and ArcCHECK™ (Sun Nuclear, Melbourne, FL) were used for measurements. For comparison with each plan, two-dimensional (2D) and 3D gamma analyses were performed using 3%/3 mm and 2%/2 mm criteria., Results: The difference between the PBC and MCC plans using 2D and 3D gamma analyses was found to be 7.85% and 28.8%, respectively. The ion chamber and 2D dose distribution measurements did not exhibit this difference revealed by the comparison between the PBC and MCC plans. However, the 3D assessment showed a significant difference between the PBC and MCC (62.7% for PBC vs 93.4% for MCC, p = 0.034)., Conclusion: Evaluation using a 3D volumetric dosemeter can be clinically useful for delivery quality assurance (QA), and the MCC should be used to achieve the most reliable dose calculation for DAT., Advances in Knowledge: (1) The DAT plan calculated using the PBC has a limitation in the calculation methods, and a 3D volumetric dosemeter was found to be an adequate tool for delivery QA of DAT. (2) The MCC was superior to PBC in terms of the accuracy in dose calculation for DAT even in the homogenous condition.

Exposure of root-knot nematode, Meloidogyne incognita to various concentrations (5-100%) of culture filtrate of Paenibacillus polymyxa GBR-1 under in vitro conditions significantly reduced egg hatch and caused substantial mortality of its juveniles. The increase in the exposure durations of juveniles to culture filtrate and its concentrations increased the mortality rate. Similarly, higher concentrations increased its inhibitory effect on egg hatch. In higher concentrations (25-100%) egg hatch was inhibited by 84-91% after 2 days of exposures as compared to control in sterile distilled water. Application of various concentrations of culture filtrate extract or bacterial suspension of P. polymyxa GBR-1 into potting soil infested with 2000 J2 of M. incognita, reduced the root galling and nematode populations and increased tomato plant growth and root-mass production compared with untreated control (P< or = 0.05). The beneficial effect of P. polymyxa GBR-1 into potted soil increased exponentially with the increase in dose concentrations. Root gall index was reduced from 4.8 to 1.4 and 1.8 when potting soil was treated with 10% concentrations of culture filtrate extract and bacterial suspension, respectively, compared with untreated control. Application of bacterial suspension of P. polymyxa GBR-1 into potted soil at 3 day pre-inoculation of nematode was the most effective followed by simultaneously and at 2 days post-inoculation; as root galling was reduced by 62.5%, 58.3% and 50.0%, respectively, compared with untreated control.

Purpose: To evaluate the acquisition of AAC skills during an initial clinical trial and assess subsequent transfer of the training to the home setting., Method: A 12-year-old male with autism was first seen in a clinical setting to establish the use of a voice-output communication device. After learning to use the device to request access to preferred objects in the clinical trial, the intervention was transferred to the home. Follow-up with the parent was conducted via e-mail and telephone. Videotapes were made of initial home-based sessions to enable evaluation of the participant's progress., Results: The programme was successful in teaching the participant to use a portable AAC device to make requests during the clinical trial and then in two home-based activities., Conclusion: An initial clinical trial with follow-up support for parents may be an efficient method for beginning AAC intervention and transferring the training procedures to the home setting.

In order to describe the degree of interaction of a molecule with its environments by descriptors, several three-dimensional descriptors have been proposed. With the physical properties calculated around a molecule, scalar, vector, and tensor (zeroth, first, and second moments) of the physical properties were calculated and were used as descriptors for calculating the similarity index between the molecules. The tensors contain the information on the spatial distribution of those physical properties around the molecule. Hydration Free Energy Density (HFED) proposed by No et al. was used to calculate HFED tensor. The descriptors were used for the similarity index calculations between substituted benzenes and between lead compounds of HIV-1 protease inhibitors. The substituted benzenes are grouped according to the similarity indices. The grouping seems reasonable from the viewpoint of a chemical sense. The lead fragments of the HIV-1 protease inhibitors have a high similarity among themselves though their chemical formulas are not very similar, the lead fragments are diverse. Although the chemical formulas are diverse, the spatial distribution of the physical properties around the molecules is similar. The descriptors have high discriminating power in the similarity calculation between the molecules.

Objectives: The significance of the coccoid forms of H. pylori is still controversial and the questions of whether these forms are viable and infective or degenerative are still open. We induced conversion from rod to coccoid forms and studied morphological changes and antigenic evolutions during this conversion and, thereby, elucidated the viability of coccoid forms., Methods: The H. pylori strain (C001) used for Western blotting was isolated from the patient with gastric cancer. The antigenic evolution during coccoid conversion of H. pylori was studied by Western blotting, using different sera from thirty patients known to be culture positive. These sera were used to reveal the total antigens of the strain cultured for 2 days (100% rod) and 15 days (> 99% coccoid). After SDS-PAGE, with 10% separating gel of total antigens (rod and coccoid), transblotting (Trans-Blot electrophoretic cell, Bio-Rad) was taken onto a nitrocellulose membrane (Bio-Rad). Then, the blots, with human sera diluted at 1/100, were developed with color reaction by goat serum anti-human IgG with alkaline phosphatase and BCIP., Results: The antigenic profiles were not changed in 46.7% (14/30 cases) and were changed in 53.3% (16/30 cases) during coccoid conversion. Antigenic fractions changed during coccoid conversion were protein band at 120 kDa and band at 35 kDa, and were not detected in coccus forms. The rest of the profiles were identical between rod and coccoid forms. The protein which disappeared include CagA (120 kDa) and porin, or adhesin (35 kDa). The morphological changes during coccoid conversion were U shaped at day 7, doughnut shaped at day 9 and full coccoid at day 15., Conclusions: The results showed that coccoid forms of H. pylori retain cellular structures similar to rod form, and some of the antigens (CagA and porin) disappeared during coccoid conversion. Therefore, coccoid form might be viable and represent one of the stages of H. pylori biological cycle.

Protoplasts were isolated from leaf mesophyll of hybrid poplar (Populus nigra X P. maximowiczii) with a mean yield of 10.4 x 10(6) protoplasts per g fresh weight using 2.0% Cellulase 'Onozuka' R-10, 0.8% Macerozyme R-10, 1.2% Hemicellulase, 2.0% Driselase, and 0.05% Pectolyase Y-23 with CPW salts solution containing 0.6 M mannitol, 0.002 M DTT, 3 mM MES at pH 5.6. A liquid plating method produced the highest frequency of dividing protoplasts (48.6%) using an MS medium without NH4NO3. The highest percent of colony formation was 22.8%, produced with fabric supported semi-solid (0.5% w/v) agar plating method using the same culture medium. Growing cell colonies and/or micro-calli were transferred to a fresh semisolid agar medium containing 0.44 μM BAP and 9.0 μM 2,4-D. Multiple shoots were produced from protoplast-derived callus after culture on MS medium containing 6.8 μM zeatin. After root induction on half-strength MS medium that lacked growth regulators, shoots were transferred to pots containing artificial soil mix.

Expiants for establishing callus cultures originated from in vitro cultured hybrid poplar (Populus alba L. X P. grandidentata Michx.). Plant regeneration was achieved from established callus cultures derived from stem internodes (SI), leaf discs (LD), and root segments (RS). Shoot regeneration from callus occurred within 4 weeks of culture on most of the media tested. Frequency of shoot formation was greatly increased by subculturing the selected organogenic calli on regeneration media. The highest rate of multiple shoot formation (an average number of 7/SI, 11/LD, and 8/RS) was obtained by using 0.05 μM IBA in combination with 22.5 μM 2iP, 22.5 μM zeatin, and 12.5 μM 2iP, respectively. Regenerated shoots were easily rooted in polyterra(™) peat plugs in transparent plastic boxes. The rooted plantlets were subsequently transferred to pots containing an artificial potting mix.

Friable calli derived from the stem tissues of Populus alba were used to establish cell suspension cultures which were characterized for in vitro growth and regeneration capacity. Suspended cells and callus recovered from these cells were maximal on a fresh weight basis using MS liquid medium containing 0.44 μM BAP and 4.52 μM 2,4-D. Shoot regeneration from the recovered callus was observed within 30 to 40 days of culture. The number of shoots was increased by subculturing the shoot-forming callus 2 to 3 times on MS medium supplemented with 19.7 μM 2iP and 0.05 μM IBA. Regenerated shoots were easily rooted on half-strength MS medium lacking growth regulators, and the plantlets were transferred to pots containing vermiculite for greenhouse growth.

Actinobacillus actinomycetemcomitans is though to play an important role in the pathogenesis of localized juvenile periodontitis (LJP). Preliminary data suggested that the serotype distribution of A. actinomycetemcomitans in Korea and the United States differ. This study evaluated A. actinomycetemcomitans prevalence, serotype distribution, and leukotoxicity in Korean LJP patients by culture, enzyme-linked immunosorbent assay, indirect immunofluorescence, and lactate dehydrogenase release from polymorphonuclear leukocytes exposed to A. actinomycetemcomitans. A. actinomycetemcomitans occurred in 75% of LJP lesions and 6% of normal sites with approximately equal distribution of serotype a, b, and c. Single serotypes were isolated from nine patients while three patients harbored two serotypes either in the same or different disease sites. A. actinomycetemcomitans leukotoxicity occurred in 22% isolates with a 69% prevalence. Individual sites harbored both leukotoxic and non-leukotoxic strains with no serotype association. The distribution of serotypes and leukotoxic strains of A. actinomycetemcomitans in Korean LJP patients differed from those reported in the United States. This suggests that serotype b may not be more important in the pathogenesis of LJP.