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Objective To investigate the effect of iTBS stimulation on walking function in patients with stroke. Methods Fifty patients with post-stroke walking dysfunction who met the inclusion criteria were selected for 3-week rehabilitation treatment, and were randomly divided into iTBS group) n = 25) and sham group) n = 25). The iTBS group was treated with conventional rehabilitation therapy combined with iTBS stimulation of contralesional cerebellum, and the sham group was treated with conventional rehabilitation therapy plus iTBS stimulation of contralesional cerebellum. Relevant indicators were analyzed before treatment and at 21 days of treatment. Lower limb motor function scores of the two groups were compared before and after treatment. Fugl-Meyer motor function lower limb activity score, Berg Balance Scale score, Brunnstrom stage) lower limb), hamstring/quadriceps) H/Q) on the affected side, Modified Barthel index ) MBI), gait analysis parameters, and TMS-MEP were used to evaluate the effectiveness of cerebellar iTBS in the rehabilitation of walking dysfunction after stroke. Results After 21 days of treatment, the improvements of Brunnstrom stage, Holden grade, Berg score, FMA score, 6-minute walking distance, NIHSS score and MBI score in iTBS group were significantly better than those in sham group) P < 0.05). After treatment, the H/Q in iTBS group was significantly higher thanbefore) P < 0.05), but there was no significant difference between the two groups) P > 0.05). Stride speed, stride frequency, stride width, single support phase on the affected side and GDI score in iTBS group were significantly improved compared with sham group) P < 0.05), and there was no significant difference in stride length between the two groups after treatment) P > 0.05). The Conclusion Contralesional cerebellar iTBS combined with routine rehabilitation could improve lower limb walking function and daily living ability of stroke patients. [ABSTRACT FROM AUTHOR]

Objective To evaluate the rehabilitation effect of innovative mirror therapy (MT) on the upper limb function and daily living activity ability of stroke patients. Methods Sixty patients with impaired hand function after stroke were enrolled and divided into the intervention n = 30 ) and control groups (n = 30) according to the random number table method. Patients in the intervention group received conventional rehabilitation training combined with innovative MT, and those in the control group received conventional rehabilitation training and conventional MT. Before treatment and 4 weeks after treatment, the Fugl-Meyer Assessment Scale for the upper limb (FMA-UE), the Fugl-Meyer Assessment Scale for the wrist and fingers (FMA-WH), and the modified Barthel Index (MBI) were evaluated to compare the rehabilitation effects between two groups. Results After 4 weeks of treatment, the FMA- UE, FMA-WH, and MBI scores of patients in two groups were higher than those before treatment (all P < 0.05 ) . The FMA-UE, FMA-WH, and MBI scores in the intervention group were higher than those in the control group (50.00 (25.75, 57.25) vs.24.00 (9.75, 51.50), 12.00 (1.75, 14.75) vs. 0 (0, 12.50), 24.50 (13.00, 28.75) vs. 13.00 (4.75, 21.00), all P < 0.05 ) . The differences before and after treatment of FMA-UE, FMA-WH and MBI scores in the intervention group were all higher than those in the control group (all P < 0.05 ) . Conclusion Compared with traditional MT, innovative MT yields higher efficacy in improving the upper limb function and enhancing daily living capability of patients with impaired hand function after stroke. [ABSTRACT FROM AUTHOR]

Objective To investigate and compare the efficacy of endoscopic-assisted hematoma evacuation and burr hole hematoma drainage combined with urokinase in the treatment of septated chronic subdural hematoma (CSDH). Methods A total of 38 patients with septated CSDH who were admitted in Peking Union Medical College Hospital and received endoscopic-assisted hematoma evacuation (endoscopy group, n = 19) or burr hole drainage combined with urokinase (burr hole group, n = 19) from January 2022 to December 2023. The change rate of the hematoma cavity was calculated, the modified Rankin Scale (mRS) and Barthel Index (BI) were used to evaluate neurological function prognosis and abilities of daily living. In addition, postoperative drainage time, postoperative hospitalization time, total hospitalization cost and incidence of cerebrospinal fluid leakage were recorded. Results The two treatment modalities did not show differences in the change rate of the hematoma cavity (t = 0.858, P = 0.396). Both endoscopy group (Z = -4.116, P = 0.000) and burr hole group (Z = -4.195, P = 0.000) had lower mRS scores on discharge than on admission, while the difference between the 2 groups on discharge was not significant (Z = -0.502, P = 0.616). The endoscopy group (Z = -1.557, P = 0.119) and burr hole group (Z = -0.091, P = 0.928) had no significant difference in BI scores on discharge versus on admission, and the difference in BI scores between the 2 groups on discharge was also not statistically significant (Z = -0.853, P = 0.394). Postoperative drainage time was longer in the endoscopy group (t = -2.488, P = 0.018), but postoperative hospitalization time was longer in the burr hole group (t = -3.894, P = 0.000). Total hospitalization cost in both 2 groups (t = 1.175, P = 0.248) and the incidence of cerebrospinal fluid leakage (Fisher's exact probability: P = 0.313) were not statistically significant. Conclusions Both neuroendoscopic surgery and burr hole drainage combined with urokinase treatment are safe and effective in treating septated CSDH. They can clear the hematoma and improve neurological function; neuroendoscopic surgery can faster improve the neurological function and shorter postoperative hospitalization time. [ABSTRACT FROM AUTHOR]

Objective This study aimed to investigate the effect of stageⅠcomprehensive cardiac rehabilitation in patients with acute ST elevation myocardial infarction (STEMI) after emergency percutaneous coronary intervention(PCI). Methods A total of 72 patients with acute ST-segment elevation myocardial infarction combined with PCI admitted to the Department of Cardiovascular Medicine of Beijing Electric Power Hospital of State Grid Corporation from June 2021 to June 2022, which were selected as the research objectsand divided into control group and observation group randomly (36 cases in each group). The control group was treated with routine nursing and health education, and the observation group with stageⅠcomprehensive cardiac rehabilitation, including initial assessment (cardiovascular comprehensive assessment), exercise training (exercise training and breathing training), daily activity suggestions and health education, discharge assessment (six-minute walking test and Barthel index assessment). The score of Barthel index (BI) at discharge, the 6-minute walking test distance (6MWD) at discharge, the incidence of major adverse cardiovascular event (MACE) during hospitalization and within one month of discharge, and the length of stay were compared between the two groups. Results After intervention, the six-minute walking test distance(6MWD)and Barthel index(BI)score in the observation group were better than those in the control group, the difference was statistically significant (P < 0.05). The incidence of major adverse cardiovascular events (MACE) during hospitalization and one month after discharge was lower in the observation group than in the control group, and the difference was statistically significant (P < 0.05). The length of hospitalization in observation group was lower than that in control groupbut there was no statistical difference (P > 0.05). Conclusion The application of phaseⅠcomprehensive cardiac rehabilitation training in patients with acute STsegment elevation myocardial infarction combined with emergency PCI could improve the patients' exercise ability, improve their ability of daily activity, reduce the incidence of major adverse cardiovascular events (MACE) in the early stage of the disease, facilitate the patients to return to their families and society as soon as possible, and improve their quality of life. It has high clinical application value. [ABSTRACT FROM AUTHOR]

Objective To explore the therapeutic effect of transcranial direct current stimulation (tDCS) with different current density on upper limb motor disorder in stroke patients. Methods A total of 45 stroke patients with upper limb motor disorder hospitalized in Xuanwu Hospital, Capital Medical University from March 2019 to June 2022 were selected and randomly divided into low current density stimulation group (low density group, 0.028 mA/cm²), medium current density stimulation group (medium density group, 0.057 mA/cm²), high current density stimulation group (high density group, 0.080 mA/cm²), 15 cases in each group. Upper limb motor function was evaluated by Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Action Research Arm Test (ARAT) before and one week after treatment, and activity of daily living was evaluated by modified Barthel Index (mBI). Results After treatment of tDCS, FMA-UE (F = 284.343, P = 0.000), ARAT (F = 180.427, P = 0.000) and mBI (F = 487.159, P = 0.000) scores in 3 groups were improved compared with those before treatment. FMA-UE (F = 2.293, P = 0.000) and ARAT (F = 2.572, P = 0.000) scores were significantly different among 3 groups, FMA-UE (t = 2.426, P = 0.029; t = 2.140, P = 0.035) and ARAT (t = 2.537, P = 0.024; t = 2.353, P = 0.028) scores in high density group and medium density group were higher than those in low density group. Conclusions tDCS is safe and effective in the treatment of upper limb motor disorder after stroke. Current densities of 0.057 and 0.080 mA/cm² are more effective than those of 0.028 mA/cm². [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: In recent years, interactive rhythmical auditory stimulation has been used in motor rehabilitation after central nervous system injuries in foreign countries. In China, research on its clinical application has also been carried out. However, there are few reports on the application of interactive rhythmical auditory stimulation in the treatment of non-acute dyskinesia following stroke. OBJECTIVE: To investigate the effect of rhythmic auditory stimulation on non-acute dyskinesia in stroke patients. METHODS: A total of 130 patients with post-stroke hemiplegia, aged 40-80 years, from March 2017 to October 2019 in the rehabilitation departments of Shenzhen Hang Seng Hospital, Affiliated Hospital of Jilin Academy of Traditional Chinese Medicine, Jilin Province People’s Hospital, Jilin Hospital of Integrative Medicine and Jilin Longtan Hospital of Traditional Chinese Medicine were included. All the patients were randomly divided into experimental group (n=55) and control group (n=75). Routine rehabilitation training was performed in both groups: once a day, five times a week, for 8 weeks. The experimental group further received rhythmic auditory stimulation once a day, five times a week, for 8 weeks. Before and after training, Fugl-Meyer assessment score, Berg balance scale score, 10-meter walking speed, Tinetti gait, FAC walking function, error value of rhythmic auditory stimulus feedback, and modified Barthel index were measured in both groups. RESULTS AND CONCLUSION: After training, Fugl-Meyer assessment score, Berg balance scale score, 10-meter walking speed, Tinetti gait, FAC walking function, rhythmic auditory stimulus motor feedback error values and modified Barthel index were significantly improved in both groups compared with pre-training values (P=0.000). At the end of training, the Fugl-Meyer assessment score, Berg balance scale score, Tinetti gait, FAC walking function, rhythmic auditory stimulation motor feedback error values and modified Barthel index value were better in the experimental group than in the control group (P=0.000); however, there was no significant difference in 10-meter walking speed between the two groups (P > 0.05). To conclude, rhythmic auditory stimulation training is an effective rehabilitation method for stroke patients with dyskinesia during convalescence and sequelae periods. The role of rhythmic auditory stimulation on walking speed remains to be explored. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

ObjectiveTo explore the effects of comprehensive nursing during treatment on incidence of complications and nursing satisfaction in patients with neuromyelitis optica （NMO）. MethodsA total of 96 NMO patients admitted to Beijing Tiantan Hospital from June 2020 to May 2022 were selected and randomly divided into control group （with routine nursing, n=48） and observation group （with comprehensive nursing, n=48）. The functional disability, daily living ability, self-management behavior, incidence of complications and nursing satisfaction were compared between two groups. ResultsAfter nursing, the extended disability status scale （EDSS） score in observation group was significantly lower than that in control group and before nursing （P＜0.05）, and the Barthel index （BI） score and self-management behaviors score were significantly higher than those in control group and before nursing （P＜0.05）. In observation group, the total nursing satisfaction （95.83%vs77.08%, χ2=7.207, P=0.007） significantly increased, and the incidence of complications （6.25%vs 20.83%, χ2=4.359, P=0.037） significantly decreased compared with those in control group. ConclusionComprehensive nursing is more conducive to restoring neurological function and activities of daily living, improving the self-management behaviors and the nursing satisfaction of patients and reducing the occurrence of complications.

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To analyze the effects of low frequency electrical stimulation combined with rehabilitation training on stroke patients with hemiplegia, motor function and self-efficacy. Methods: A total of 156 stroke patients with hemiplegia admitted to our hospital from May 2019 to January 2022 were selected as research objects and randomly divided into control group and observation group, with 78 cases in each group. The control group was given routine symptomatic support treatment, plus rehabilitation training. The observation group was additionally treated with low-frequency electrical stimulation on the basis of the control group, and the efficacy was evaluated after continuous treatment for 8 weeks. The therapeutic effect was evaluated according to the Brunnstrom grade improvement of lower limbs. lower limb Fugl-Meyer Motor Function Scale (FMA), Berg Balance Scale (BBS), modified Barthel Index (MBI) and general Self-efficacy Scale (GSES) scores were compared between the two groups before and after treatment. Results: The total effective rate of the observation group was 96.15%, which was significantly higher than that of the control group (84.62 %) (P＜0.05). Compared with control group, lower limb FMA score and BBS score in observation group were higher after treatment (P＜0.05). Compared with the control group, the MBI score and GSES score of the observation group were higher after treatment (P＜0.05). Conclusion: Low frequency electrical stimulation combined with rehabilitation training in the treatment of stroke patients with hemiplegia has obvious effects, can effectively improve motor function and quality of life, improve self-efficacy, worthy of further research and application. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To systematically evaluate the clinical efficacy and safety of Naoxueshu oral liquid in the treatment of hemorrhagic stroke bases on Meta-analysis. METHODS: CNKI, Wanfang Data, VIP, the Cochrane Library, PubMed, Embase and other databases were retrieved to collect the randomized controlled trial of Naoxueshu oral liquid in the treatment of hemorrhagic stroke, the retrieval time was from the establishment of the database to Dec. 2022. The literature was screened according to the pre-determined inclusion and exclusion criteria, quality assessment and data extraction were conducted by two researchers respectively, and cross-checked. The risk bias assessment tool recommended by Cochrane was used for methodological quality evaluation. Meta-analysis was performed by RevMan 5. 4 software. RESULTS: Totally 13 studies were enrolled, including 1 059 patients. Results of Meta-analysis showed that compared with conventional treatment alone, Naoxueshu oral liquid combined with conventional treatment could improve the total effective rate of patients with hemorrhagic stroke (RR = 1. 26,95%CI = 1. 16-1. 37,P<0. 000 01) and reduce the volume of intracerebral hematoma (MD= -3. 13,95%CI = -4. 45--1. 81,P<0. 000 01), improve the score of National Institutes of Health Stroke scale (MD= -3. 43,95%CI = -5. 55--1. 31,P = 0. 002), improve Barthel index score( MD = 4. 98, 95% CI = 1. 18-8. 78, P = 0. 01 ), the differences were statistically significant. There was no significant difference between two groups in reducing the volume of perihematoma edema ( MD = - 1. 85,95% CI = -4. 02-0. 31,P = 0. 09). In terms of safety, no severe adverse events occurred in the Naoxueshu oral liquid combined with conventional treatment groups. CONCLUSIONS: Based on the existing clinical evidence, conventional treatment combined with Naoxueshu oral liquid is better than conventional treatment alone in the treatment of hemorrhagic stroke. However, due to the low methodological quality of the included studies, clinical studies with strict methodological design and quality control are needed to provide high-quality evidence. [ABSTRACT FROM AUTHOR]

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To observe the effects of Bobath therapy combined with low-frequency repetitive transcranial magnetic stimulation on motor function, neurological function and balance ability in stroke patients with hemiplegia. Methods: The study subjects were 148 stroke patients with hemiplegia who were admitted to our hospital from May 2020 to May 2022. According to the method of random number table, they were divided into control group (Bobath therapy, 74 cases) and study group (low-frequency repetitive transcranial magnetic stimulation combined with Bobath therapy, 74 cases). The balance ability [Berg Balance Scale (BBS)],neurological function [National Institutes of Health Stroke Scale (NIHSS)], daily living self-care ability [modified Barthel Index (MBI)],motor function [Fugl-Meyer upper limb motor function assessment scale (FMA-UE), Fugl-Meyer lower limb motor function assessment scale (FMA-LE)], coagulation function [prothrombin time (PT), fibrinogen (FIB), D-Dimer (D-D), activated partial thromboplastin time (APTT)] changes were observed in the two groups. Results: 20d after treatment, NIHSS score decreased and MBI score increased in both groups, and the degree of change in the study group was greater than that in the control group (P＜0.05). The scores of FMA-UE and FMA-LE in the two groups at 20 d after treatment increased, and the study group was higher than the control group (P＜0.05). The BBS score of the two groups at 20 d after treatment increased, and the study group was higher than the control group (P＜0.05). FIB, APTT,D-D and PT of the two groups at 20 d after treatment decreased, and the study group was lower than the control group (P＜0.05)Conclusion: Low-frequency repetitive transcranial magnetic stimulation combined with Bobath therapy for stroke patients with hemiplegia can improve their coagulation function, recover their neurological function, and then improve their balance and motor function, and improve their daily living ability. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the efficacy of Tiandan Tongluo capsule combined with butylphthalide soft capsule in the treatment of acute cerebral infarction (ACI) and its effects on inflammatory factors and cerebral hemodynamics. Methods: According to the random number table method, 100 patients with ACI who were received in Hefei First People’s Hospital from January 2019 to December 2021 were divided into control group (50 cases, treated with butylphthalide soft capsule) and observation group (50 cases, treated with Tiandan Tongluo capsule combined with butylphthalide soft capsule). The efficacy, scale score, inflammatory factors and cerebral hemodynamics in the two groups were compared, and the incidence of adverse reactions during treatment in the two groups was counted.Results: The total clinical effective rate in the observation group was 84.00% higher than 66.00% in the control group (P＜0.05). Compared with the control group, after treatment, the Barthel index score in the observation group increased, and the score of national Institutes of Health Stroke Scale (NIHSS) decreased (P＜0.05). After treatment, interleukin-6 (IL-6) and hypersensitive C-reactive protein (hs-CRP) in the observation group were lower than those in the control group, and interleukin-10 (IL-10) was higher than that in the control group (P＜0.05). After treatment, the resistance index (RI) in the observation group was lower than that in the control group, and the peak systolic blood flow velocity (Vs), mean blood flow velocity (Vm) and diastolic blood flow velocity (Vd) were higher than those in the control group (P＜0.05). There was no difference in the incidence of adverse reactions between the two groups (P＞0.05). Conclusion:Tiandan Tongluo capsule combined with butylphthalide soft capsule can reduce the levels of inflammatory factors and improve cerebral hemodynamics in patients with ACI, the effect is remarkable. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To study the effect of cilostazol after thrombolytic therapy with recombinant human tissue plasminogen activator (rt-PA) in patients with acute cerebral infarction and its effect on Serum Platelet lysosomal membrane protein (CD63), α Role of granule membrane glycoprotein (CD62P) and platelet activating factor (PAF). 90 patients with acute cerebral infarction treated in our hospital from February 2020 to February 2022, they were randomly divided into observation group and control group, with 45 cases in each group. Both groups were treated with rt-PA thrombolytic therapy, the control group was treated with aspirin after thrombolytic therapy, and the observation group was treated with cilostazol on the basis of the control group, and were treated continuously for 14 days. The clinical efficacy, changes of serum CD62p, CD63, PAF, whole blood viscosity, plasma viscosity, erythrocyte specific volume (HCT), NIHSS score, Barthel scale (Barthel Index) score, and incidence of bleeding events were compared between the two groups. The total effective rate of the observation group was 91.11%, which was higher than 73.33% of the control group, with statistical significance (P<0.05); the serum CD62p, CD63 and PAF in observation group were lower than those in control group, with statistical significance (P<0.05); the whole blood viscosity, plasma viscosity and HCT in observation group were lower than those of control group, with statistical significance (P<0.05); the NIHSS score in observation group was lower than control group, and Barthel index was higher than control group, with statistical significance (P<0.05); comparison of the total incidence of bleeding events between the two groups, with statistical significance (P＞0.05). Cilostazol have a significant effect on acute cerebral infarction patients after rt-PA thrombolytic therapy, which can effectively reduce the expression of serum CD62p, CD63 and PAF and improve platelet function, with good safety and worthy of clinical promotion. [ABSTRACT FROM AUTHOR]

OBJECTIVE: There is still a lack of effective treatments for spinal cord injury. Cell therapy could be a promising treatment method, in which human umbilical cord mesenchymal stem cells have received wide attention, because of its easy availability, low cost, less ethical issues, and low immunogenicity. At present, it has not been widely used in clinical practice, and its effectiveness and safety are still controversial. A meta-analysis was used to evaluate the efficacy and safety of human umbilical cord mesenchymal stem cells in the treatment of spinal cord injury. METHODS: We searched English databases (PubMed, Web of Science, Cochrane, and EMbase) and Chinese databases (CNKI, Wanfang Medical Network, and VIP), and collected clinical articles on human umbilical cord mesenchymal stem cells in the treatment of spinal cord injury. The retrieval period was from the establishment of the database to April 2021. Two investigators independently read the included studies, extracted the data, and assessed the quality. The randomized controlled trials were scored using the modified Jadad scoring scale, and the Cochrane risk bias assessment tool was used to assess the risk of bias. The cohort studies were evaluated using the NOS scale. Meta-analysis was performed using RevMan5.3 software. RESULTS: A total of 10 studies involving 370 patients, containing 6 randomized controlled trials and 4 cohort studies, were included. The overall quality of the studies was high. Results of the meta-analysis showed that (1) the ASIA sensory function score (MD=5.20, 95%CI:3.50-6.90, P < 0.000 01), the improvement rate of AIS grading (RR=2.26, 95%CI:1.40-3.65, P=0.000 8), and the Barthel index (MD=5.12, 95%CI:1.04-9.20, P=0.01) were higher in the human umbilical cord mesenchymal stem cell treatment group than those in the control group. (2) Compared with the control group, there was no significant difference in ASIA motor function score (MD=3.48, 95%CI:-0.14-7.10, P=0.06), ASIA pinprick sensation score (MD=7.58, 95%CI:-0.44-15.59, P=0.06) and ASIA light touch score (MD=7.67, 95%CI:-0.42-15.77, P=0.06) in the human umbilical cord mesenchymal stem cell treatment group. (3) Sensitivity analysis showed that the ASIA motor function score was higher in the human umbilical cord mesenchymal stem cell treatment group than that in the control group (MD=6.14, 95%CI:4.46-7.81, P < 0.000 01), and the results remained consistent with the previous one for the activities of daily living. In the 10 included articles, no serious adverse reactions were reported, but minor adverse reactions did exist and disappeared after symptomatic treatment. CONCLUSION: The available clinical evidence shows that human umbilical cord mesenchymal stem cells are safe and effective in the treatment of spinal cord injury, with significant improvement in patients’ sensory and motor functions as well as their activity of daily living. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To retrospectively compare the efficacy of neuroendoscopic surgery and small bone window craniotomy in the treatment of hypertensive intracerebral hemorrhage (HICH). Methods: The clinical data of 83 patients with HICH who were treated in the 909th Hospital of Joint Logistics Support Force from July 2018 to March 2021 were retrospectively selected. According to the different surgical methods, the patients were divided into group A(n=41) and group B(n=42). Patients in group A were treated with small bone window craniotomy and patients in group B were treated with neuroendoscopic surgery. The perioperative indexes, incidence of complications, neurological function, living ability, nerve injury indexes and prognosis of the two groups were compared. Results: Compared with group A, group B significantly shortened the operation time and hospital stay, reduced the amount of intraoperative bleeding and increased the clearance rate of hematoma(P<0.05). One week after operation, the National Institutes of Health Stroke Scale (NIHSS) score in group B was lower than that in group A, and the Barthel index score was higher than that in group A (P<0.05). The levels of neuron specific enolase (NSE), S100B protein (S100B), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in group B were lower than those in group A one week after operation (P<0.05). The incidence of complications in group B was lower than that in group A(P<0.05). The rate of good prognosis in group B was higher than that in group A (P<0.05). Conclusion: Neuroendoscopic surgery and small bone window craniotomy can obtain good curative effects in the treatment of HICH. Among them, neuroendoscopic surgery has a more significant effect in shortening the operation time and hospital stay, reducing the amount of intraoperative bleeding and the incidence of complications, improving the clearance rate of hematoma, reducing the damage of nerve function, promoting the improvement of patients' living ability and improving patients' prognosis. [ABSTRACT FROM AUTHOR]

To observe the effects of dengyinnaotong capsule combined with butylphthalide soft capsule on cerebral hemodynamics and inflammatory factors in patients with acute cerebral infarction(ACI). 120 patients with ACI who were treated in our hospital from April 2019 to March 2021 were selected. According to the envelope lottery method, the patients were divided into control group and combined group, with 60 cases. The control group was treated with butylphthalide soft capsule, and the combined group was treated with butylphthalide soft capsule and dengyinnaotong capsule. The curative effect, cerebral hemodynamics, inflammatory factors and related scale scores of the two groups were compared, and the occurrence of adverse reactions during the treatment of the two groups were recorded. Compared with the control group (51.67%), the total clinical effective rate of the combined group (71.67%) was further increased(P<0.05). After treatment, the modified Barthel index score of the combined group was higher than that of the control group, and the National Institutes of Health Stroke Scale score (NIHSS) was lower than that of the control group (P<0.05). The peak systolic velocity (Vs) and mean blood flow velocity (Vm) of the combined group after treatment were higher than those of the control group, and the pulsatile index (PI) was lower than that of the control group (P<0.05). After treatment, the levels of tumor necrosis factor-α(TNF-α), serum hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) of combined group were lower than those of control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). The treatment of patients with ACI on the basis of butylphthalide soft capsule combined with dengyinnaotong capsule can significantly reduce neurological impairment, improve cerebral hemodynamics, reduce the level of inflammatory factors in the body, and promote the improvement of self-care ability. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the effects of minimally invasive hematoma evacuation with small bone window at different operation time on inflammatory factors, prognosis and serum levels of angiopoietin-1 (Ang-1), endothelin (ET) and vasopressin (AVP) in patients with hypertensive intracerebral hemorrhage (HICH). Methods: From January 2018 to December 2019, 130 patients with HICH in our hospital were selected, and divided into early group (n=64, operation within 6~24 hours after onset) and super early group (n=66, operation within 6 hours after onset) according to different operation time. Perioperative indexes, inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor -α(TNF-α), high sensitivity C-reactive protein (hs-CRP)] levels, prognosis, serum Ang-1, ET, AVP levels, modified Barthel Index (BI), National Institutes of Health Stroke Scale (NIHSS) score, occurrence of complications were compared between the two groups. Results: The hospitalization time of super early group was shorter than that of early group, and intraoperative blood loss was less than that of early group (P<0.05). There was no difference in hematoma clearance rate and operation time between the two groups (P>0.05). 7d after operation, the IL-6, TNF -α, hs-CRP, Ang-1, ET, AVP and NIHSS score of early group and super early group were decreased compared with those before operation, and those of super early group were lower than those of early group (P<0.05). 7 d after operation, the BI score of early group and super early group was increased compared with that before operation, and that of super early group was higher than that of early group (P<0.05). There was no difference in the incidence of complications between the two groups (P>0.05). The survival rate of the super early group was higher than that of the early group (P<0.05). Conclusion: Minimally invasive hematoma evacuation with small bone window within 6 hours after onset of HICH can effectively reduce surgical trauma and improve the ischemic state of brain tissue, promote the recovery of self-help ability and neurological function, reduce the serum inflammatory factors levels, improve the prognosis of patients, improve the quality of life of patients and the security is good. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To study Effect of tirofiban combined with butylphthalide on serum Heme oxygenase-1（HO-1), nitric oxide（NO), angiogenin-1（ANG-1), vascular endothelial growth factor（VEGF） in patients with acute cerebral infarction beyond time window.Methods: 141 patients with acute cerebral infarction beyond the time window treated in our hospital from January 2018 to January 2020 were selected and divided into combination group（n=71） and single drug group（n=70） by random number table method. The mono-drug group was given butylphthalide treatment, and the combination group was given tirofiban treatment on the basis of mono-drug group.Clinical efficacy, HO-1, NO, VEGF, ANG-1, the National Institutes of Health Stroke Scale（NIHSS), Barthel index（Barthel), thrombin time（TT), prothrombin time（PT), fibrinogen（FIB） levels and the incidence of drug complications were compared between the two groups. Results: After treatment, the total effective rate of the two groups was significantly different（P<0.05）; before treatment, there was no significant difference in serum HO-1, no, VEGF, Ang-1 between the combined group and the single drug group; after treatment, the serum HO-1, no, VEGF in the combined group and the single drug group decreased with time, and the combined group was lower than the single drug group, and Ang-1 increased with time, and the combined group was higher than the single drug group, the difference was significant Before treatment, there was no significant difference in NIHSS and Barthel between the combined group and the single drug group; after treatment, NIHSS in the combined group and the single drug group decreased with the passage of time, and Barthel in the combined group increased with the passage of time, and the combined group was higher than the single drug group, the difference was significant（P<0.05). Conclusion: The effect of tirofiban combined with butylphthalide in patients with acute cerebral infarction over time window is significant, which may be related to the effective improvement of serum HO-1, no, VEGF, Ang-1 levels, and does not increase adverse reactions. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To analyze the factors affecting the self care ability of the patients with acute mushroom poisoning, and to compare the differences of clinical indexes and prognosis between the patients with unable self care and the patients with basic self care. Methods: A total of 184 cases of acute mushroom poisoning treated in the Affiliated Hospital of Southwest Medical University from March 2017 to November 2018 were selected. The clinical data and the scores in each item of Barthel index were collected. The cases were divided into the unable self care group (c:(60 points, 63 cases) and basic self care group (> 60 points,121 cases) according to the total score value. The differences in the clinical indicators and prognosis were analyzed and compared between the two groups by using the multivariate logistic regression model. Results: The sex, age, hospitalization time, platelet (Plt), hemoglobin(Hb), creatinine, albumin, bilirubin and proportion of complicating liver failure had no statistical differences between the two groups(P > 0.05). Compared with the basic self care group, the levels of glutamic transaminase (ALT ), glutamic oxalacetic transaminase (AST), prothrombin activily(PTA), activated partial thromboplastin time (APTT), white blood cells count, red blood cells count, urea and proportion of complicating renal failure in the unable self care group were higher, and the differences were statistically significant (P<0.05). Among 184 cases, 8 cases died with the mortality rate of 4. 35% and all death cases occurred in the unable self care group, the mortality rate had statistical difference between the two groups (P < 0.05). The higher the PT A and RBC, the lower the risk of unable self care (P< 0.05), the higher the urea level, the higher the risk of unable self care (P< 0. 05). Conclusion: The patients with acute mushroom poisoning and unable self care should adopted the pertinent nursing measures, recover their living self care ability to the utmost extent, reduce the occurrence rate of complications and increase the survival rate. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the effect of acupuncture combined with alternating vertical vibration training on balance function, hemorheology and quality of life of stroke hemiplegia patients. Methods: 136 stroke hemiplegia patients who were admitted to our center from May 2017 to August 2019 were selected, they were randomly divided into the control group (n=68) and the study group (n=68) according to the number table method. The patients in the control group were given routine rehabilitation training. The patients in the study group were combined with acupuncture and alternate vertical vibration training on the basis of the control group. The curative effect, balance function, hemorheology and quality of life were compared. Results: 1 month after treatment, the Berg balance scale (BBS), functional gait test (FGA) and specific activity balance confidence scale (ABC) scores in two groups increased, and the study group was higher than the control group (P<0.05). 1 month after treatment, Barthel index (BI) score in two groups increased at 1 month after treatment, and the study group was higher than the control group (P<0.05). The whole blood viscosity, plasma viscosity, hematocrit and fibrinogen in the two groups decreased at 1 month after treatment, and the study group was lower than the control group (P<0.05). The total clinical effective rate in the study group was 86.76% (59/68), which was higher than 60.29% (41/68) in the control group (P<0.05). Conclusion: Acupuncture combined with alternative vertical vibration training in the treatment of stroke patients with hemiplegia, it can effectively improve the balance function, hemorheology and quality of life of patients, which has a good curative effec [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Proximal femoral nail antirotation is a commonly used internal fixation system for the treatment of femoral intertrochanteric fracture in the elderly. Simultaneously, the elderly are often associated with knee osteoarthritis, which may affect the postoperative effect of femoral intertrochanteric fracture. OBJECTIVE: To investigate the effect of knee osteoarthritis at the fracture side on the efficacy of postopenxtine proximal femoral nail antirotation in elderly femoral intertrochanteric fractures. METHODS: Totally 92 patients aged over 65 years old with femoral intertrochanteric fractures treated with proximal femoral nail antirotation internal fixation were divided into five groups according to the preoperative knee X-ray Kellgren-Lawrence grade: grade 0 as group A (13 cases), grade I as group B (18 cases), grade II as group C (23 cases), grade III as group D (22 cases), and grade IV as group E (16 cases). The hospitalization time, postoperative complications, postoperative landing time, fracture healing time, hip Harris score and Barthel index score of daily living ability at 1, 3 and 6 months after operation were recorded in the five groups. This study was approved by the Ethics Committee of Affiliated Hospital of Chengde Medical University. RESULTS AND CONCLUSION: (1) There was no significant difference in the length of hospital stay among the five groups (P > 0.05). (2) The postoperative landing time and fracture healing time of group D and group C were longer than those in group A, group B, and group C (P < 0.05). (3) The number of postoperative complications of group C was more than those in group A and group B (P < 0.05). The number of postoperative complications of group D and group E was more than that in group A, group B and group C (P < 0.05). (4) The scores of Harris and Barthel index of group C and D were lower than those in group A and B at 1, 3 and 6 months after operation (P < 0.05). The scores of Harris and Barthel index of group E was lower than those in group A, group B, group C and group D at 1, 3 and 6 months after operation (P < 0.05). (5) The results showed that the higher the grade of knee osteoarthritis, the greater the influence on the postoperative efficacy of proximal femoral nail antirotation in the treatment of elderly patients with femoral intertrochanteric fracture. It is manifested by increased postoperative complications, prolonged postoperative landing time and fracture healing time, and the decrease of hip function and ability of daily living. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the effect of tianma gouteng decoction combined with xingnao kaiqiao needling as auxiliary on vascular endothelial function, cerebrovascular reserve function and alpha-granular membrane protein (CD62P), lysosome intact membrane protein (CD63) of patients with acute cerebral infarction. Methods: 80 cases of patients with acute cerebral infarction in our hospital from 2017 January to December 2019 were selected. According to the random indicator method, they were divided into the control group (n=40, treated with conventional treatment) and the observation group (n=40, treated with tianma gouteng decoction combined with xingnao kaiqiao needling as auxiliary on the basis of conventional treatment). The clinical efficient, United States national institutes of health stroke scale (NIHSS) score, hasegawa intelligence scale (HDS) score, Barthel index, endothelial function indexes [including nitric oxide (NO), endothelin 1 (ET-1)], cerebrovascular reserve function indexes [cerebrovascular reserve (CVR), pulse index (PI)] and the levels of platelet CD62P and CD63 of two groups before and after treatment were compared. Results: Total effective rate of observation group was 92.50% (37/40), which was significantly higher than the control group [70.00% (28/40)], and the difference was statistically significant (P<0.05). NIHSS score of the observation group after treatment was significantly lower than that in the control group, while HDS score and Barthel index were significantly higher than that in the control group (P<0.05). The levels of serum NO and CVR after treatment in the observation group were significantly higher than those in the control group, and the expression levels of serum ET-1, PI and platelet CD62P and CD63 were significantly lower than those in the control group (P<0.05). Conclusion: On the basis of conventional treatment, tianma gouteng decoction combined with xingnao kaiqiao needling as auxiliary has a significant clinical effect in the treatment of acute cerebral infarction, which can significantly improve vascular endothelial function, cerebrovascular reserve function and nerve function, improve the quality of life, and improve the expression of platelet CD62P and CD63. [ABSTRACT FROM AUTHOR]

Background: Most advanced lung cancer patients have already received many types of treatment before starting immunotherapy. Compared with advanced lung cancer patients under first-line treatment, those receiving immunotherapy are vulnerable to many health problems and increased frailty. Purpose: This study was designed to investigate frailty in advanced lung cancer patients before starting immunotherapy. Methods: A total of 52 pre-immunotherapy patients completed the survey. Frailty status was determined using the Fried standard and survey questionnaires included the Barthel Index, Center for Epidemiologic Studies Depression Scale, the Chinese version of scales of international physical activities questionnaire (short version). In addition, the handgrip and 4.6-meter walk speed of the participants were measured. Result: The ratio of frailty was 17.3%, with comorbidities (p = .023), body mass index (p = .004), Eastern Cooperative Oncology Group Status (p < .001), activities of daily living status (p < .001), albumin (p = .042), and C-reactive protein (p = .048) all associated with frailty. Conclusions/Implications for Practice: In this study, weight loss and low physical activity were the main symptoms of frailty in patients with advanced lung cancer. Therefore, healthcare workers should assess the nutrition and physical activity status of patients before initiating immunotherapy. We suggest that clinical care workers provide frailty care to patients before administering immunotherapy. [ABSTRACT FROM AUTHOR]

Objective To analyze the effect of emergency nursing team model combined with chain management on the emergency efficiency and treatment effect of acute stroke. Methods A total of 98 patients with acute stroke admitted to Dongfeng People's Hospital of Zhongshan City from December 2018 to May 2020 were selected and divided into an observation group (n =49) and a control group (n =49) according to the random number table. The control group received routine nursing, and the observation group received the emergency nursing team model combined with chain management on the basis of routine nursing. The treatment effect, first aid efficiency, occurrence of adverse events, and the National Institutes of Health Stroke Scale (NIHSS) scores and Barthel Index (BI) scores before and after thrombolysis were compared between the two groups. Results The total effective rate of treatment in the observation group was 97. 96%, which was significantly higher than 81. 63% in the control group (P <0. 05). The triage time, waiting time and emergency treatment time of the observation group were significantly shorter than those of the control group (all P < 0. 05). After thrombolysis, the NIHSS scores of the two groups were lower than those before thrombolysis, and the BI scores were higher than those before thrombolysis. The NIHSS scores of the observation group were lower than those of the control group, and the BI scores were higher than those of the control group. The differences were statistically significant (all P < 0. 05). The incidence of adverse events in the observation group was 2.04%, and 8.16% in the control group. The difference was not statistically significant (P > 0. 05). Conclusion The application of emergency nursing team model combined with chain management in acute stroke can improve the effect and efficiency of emergency treatment, improve neurological function, improve the ability of daily life, and reduce the incidence of adverse events. [ABSTRACT FROM AUTHOR]

Objective To analyze the influence of emotional rehabilitation combined with targeted nursing on the mental state and rehabilitation effect of patients with cerebral infarction. Methods 100 patients with cerebral infarction received from January 2018 to January 2020 in the Affiliated Hospital of Xuzhou Medical University were divided into a control group and an observation group with 50 cases respectively by the random number table method. The control group received routine care and the observation group received emotional rehabilitation combined with targeted nursing. The mental state and rehabilitation effect were compared between the two groups. Results There was no significant diference in Symptom Checklist-90 (SCL-90) score, Short-Form Fugl-Meyer Assessment of Motor Recovery score and Barthel Index between the two groups of patients with cerebral infarction before the intervention ( all P > 0. 05). After the intervention, SCL-90 score of the observation group was lower than that of the control group, and the Fugl-Meyer score and Barthel Index were higher than those of the control group (aü P < 0.05). Conclusion Emotional rehabilitation combined with targeted nursing can eefectively improve the mental state of patients with cerebral infarction and improve their rehabilitation effect. It is worthy of promotion and application in clinical nursing work. [ABSTRACT FROM AUTHOR]

Background: Studies have shown that oral health is closely related to systemic diseases. Poor oral hygiene may lead to dental caries and periodontal disease and also increase the risk of cardiovascular disease. Patients with stroke have a possibility of recurrence, and good oral health is expected to benefit their general health. Nevertheless, nursing research exploring the oral health and oral hygiene behaviors of stroke patients has been rare. Purpose: To explore the factors significantly associated with oral health status and oral hygiene behaviors in patients with stroke. Method: A cross-sectional research design with convenient sampling was used. Information on health promoting behaviors and oral health status was collected in a teaching hospital in southern Taiwan. A multivariate linear regression model was applied to explore the factors associated with oral health status in patients with stroke. Results: One hundred and eight-five patients with stroke were enrolled in this study. The average number of real teeth was 11.3 and the average score for oral health status was 4. The univariate analysis showed that being 65 years of age or older, having an education level below primary school, having a lower Barthel index score, having a higher modified Rankin scale score, not brushing and flossing, not having a regular tooth cleaning, having a lower of health promotion score, and having insufficient water intake levels were all associated with a worse oral health status. The stepwise regression analysis showed that factors affecting oral health status include health promotion behaviors, age, tooth brushing, and water intake, which, together, accounted for 28.5% of the total variance. Conclusions/Implications for Practice: The findings indicate that oral health status, oral hygiene behaviors, and health promoting behaviors are inadequate among patients with stroke. Clinicians should promote health-related behaviors early to their patients with stroke, specifically in terms of implementing proper oral hygiene behaviors in daily routine care. [ABSTRACT FROM AUTHOR]