1. Simultaneous extraction of hydroxylated polycyclic aromatic hydrocarbons and catecholamines with magnetic boronic acid hypercrosslinked polymers.
- Author
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Hu, Kai, Pang, Tiantian, Yang, Cheng, Han, Pengzhao, Li, Lixin, Wang, Pan, Zhang, Zhenqiang, Zhao, Wenjie, and Zhang, Shusheng
- Subjects
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IRON oxides , *BORONIC acids , *CELLULOSE acetate , *POLYMERS , *CATECHOLAMINES , *POROSITY , *CIGARETTE smoke - Abstract
• Magnetic boronic acid hypercrosslinked polymer was prepared via one-pot strategy. • The sorbent possessed good extraction capability for OH-PAHs and catecholamines. • Boronate affinity and π-π stacking played important role in the extraction. • The proposed method provides lower LODs and higher precisions. Urinary hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and catecholamines (CAs) are important biomarkers of PAHs exposure. In this study, a novel magnetic boronic acid hypercrosslinked composite (Fe 3 O 4 @HCP-BA) is synthesized using a facile one-pot strategy and applied as a sorbent for the simultaneous extraction of OH-PAHs and CAs in urine samples. The synthesized Fe 3 O 4 @HCP-BA composites are characterized by rich pore structure, highly specific surface area, good magnetic response, and excellent selectivity and adsorption efficiency (range: 65.26–496.71 and 1227.3–1581.8 µmol g−1 for CAs and OH-PAHs, respectively). The mechanisms governing the adsorption of the OH-PAHs and CAs to the Fe 3 O 4 @HCP-BA composites were systematically studied via adsorption kinetics, isotherm models, XPS characterization, and molecular simulation. The resultant Fe 3 O 4 @HCP-BA composite-based MSPE/HPLC-FLD method exhibited good linearity (R2 > 0.9916), low limits of detection (0.2–0.3 pg mL−1 and 0.2–0.3 ng mL−1 for OH-PAHs and CAs, respectively), and good precision (intra-day and inter-day RSDs < 11.1%). The analysis of CAs and OH-PAHs in the urine samples from 14 smokers and 14 non-smokers revealed a positive correlation between the concentrations of CAs and OH-PAHs. Our findings not only establish the proposed method as a green, environmentally friendly, and simple strategy for preparing magnetic adsorbents, but also confirm it as a promising alternative method for accurate determination of OH-PAHs and CAs in biological samples. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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