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This article discusses a study on the evolution of antibiotic responses in bacteria in relation to the dynamics of drug delivery. The researchers conducted experiments on tetracycline resistant E. coli cultures and found that gradual increases in drug concentrations led to fine-tuning mutations, while periodic exposure to large drug doses resulted in the loss of regulation of resistance. A mathematical model showed that sudden drug exposures overwhelmed regulated responses. These findings help explain the frequent loss of regulation of resistance in clinical pathogens. The article emphasizes the importance of understanding how the dynamics of drug administration can impact the evolution of antibiotic responses in bacteria. [Extracted from the article]

A recent study conducted by researchers at the Butantan Institute in Sao Paulo, Brazil, focused on multidrug resistance (MDR) in the Lucena 1 cell line, derived from the human chronic myeloid leukemia cell line K562. The study aimed to explore the underlying mechanisms driving MDR in this cell line and identified qualitative differences in protein expression compared to the K562 cell line. The researchers found that the ATP-dependent efflux pump, Translocase ABCB1, and unique isoforms of Tubulin were key contributors to drug resistance in Lucena 1. The study provides new insights into the MDR phenotype and its consequences in cellular pathways, which could lead to innovative cancer models and antitumor strategies. [Extracted from the article]

A study conducted at Hunan University in Changsha, People's Republic of China, has developed G-quadruplex-based potassium-specific transmembrane channels that induce cancer cell apoptosis by perturbing potassium ion homeostasis. The channels facilitate intracellular potassium efflux, disrupting cellular ion balance and leading to cancer cell death. The study demonstrates that these channels have high transport activity and ion selectivity, and they effectively purge cancer cells through potassium efflux-mediated apoptosis. The lipophilic G-quadruplex exhibits antitumor activity without systemic toxicity, making it a promising avenue for future anticancer therapy. [Extracted from the article]

A recent study conducted by researchers at the National Institute of Agricultural Sciences in South Korea examined the antibiotic resistance of acetic acid bacteria (AAB) originating from vinegar. The researchers found that all 26 strains of AAB exhibited resistance to aztreonam and clindamycin, with Komagataeibacter species showing a 50% resistance rate to ciprofloxacin. Genomic analysis of one strain identified intrinsic resistance mechanisms, such as multidrug efflux pumps. These findings contribute to our understanding of antibiotic resistance in AAB and highlight the need for standardized testing methods and further genetic studies. [Extracted from the article]

The article discusses the challenge of identifying and understanding novel genes from microbiomes. The authors propose a method called METa assembly, which allows for the creation of functional metagenomic libraries using smaller amounts of DNA. They demonstrate that this method can be used to link certain genes to antibiotic resistance and potential resistance to the antidiabetic drug acarbose. The study suggests that METa assembly can overcome the limitation of requiring large amounts of DNA and expand the possibilities for functional metagenomic research. [Extracted from the article]

A report from the School of Biosciences highlights the growing problem of antibiotic resistance, which is considered a serious threat to global health and food security. The report discusses different categories of antibiotic resistance, such as natural, acquired, cross-resistance, multidrug, and pan-drug resistance, and explains various mechanisms by which bacteria develop resistance. It emphasizes the need for global action to combat antimicrobial resistance and calls for continuous surveillance of antibiotic resistance gene dissemination. The report also discusses the clinical consequences of resistant bacteria and offers recommendations to prevent further spread. [Extracted from the article]

A report from Northwestern Polytechnic University in Shenzhen, China, discusses the co-contamination of antibiotics and nitrogen and its potential harm to ecological safety and human health. The study focuses on the use of sulfur-driven autotrophic denitrification (SAD) to treat antibiotics-laden organic deficient wastewater. The research found that SAD sludge was able to remove 80.78% of the antibiotic Norfloxacin (NOR), with biodegradation being the dominant removal route. The study also identified the presence of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in the SAD system. The research provides insights into the treatment of NOR-laden wastewater using sulfur-mediated biological processes. [Extracted from the article]

A recent study conducted by researchers at the City University of Hong Kong has utilized nanopore sequencing technology to analyze multidrug-resistant bacterial strains. The study successfully assembled the genomes of eight bacterial strains and their 18 plasmids using nanopore sequencing data. The research identified diverse antibiotic resistance patterns and specific resistance genes in the test strains, providing valuable insights into the genetic characteristics of multidrug-resistant bacteria. The findings demonstrate the practicality of nanopore sequencing technology for detecting resistance elements in bacterial pathogens. [Extracted from the article]

A recent study conducted by researchers at Tehran University of Medical Sciences in Iran explores new strategies for targeting bacterial biofilm-related genes using nanoparticle-based therapies. Biofilm is a persistent infection that poses challenges due to its resistance to traditional treatments and antibiotics. Nanoparticles, such as silver, zinc oxide, titanium dioxide, copper oxide, and iron oxide, have shown promise in inhibiting biofilm formation by interfering with gene expression in bacteria. However, the potential environmental impact and cytotoxicity of nanoparticles should be carefully considered. This research provides insights into potential therapeutic targets for controlling biofilm infections. [Extracted from the article]

A recent report from Kanazawa University in Japan discusses research on drug resistance in Saccharomyces cerevisiae, a type of yeast. The study focuses on the Rpd3L complex, which includes the histone deacetylase Rpd3 and the DNA binding proteins Ume6 and Ash1, and its role in transcriptional regulation. The researchers found that RPD3 and UME6 are responsible for the activation of ABC transporter genes and pleiotropic drug resistance in r0 cells, which lack mitochondrial DNA. This finding may have implications for understanding drug resistance in both yeast and pathogenic Candida species. [Extracted from the article]

A recent study conducted at Claude Bernard University Lyon 1 in France has focused on understanding the mechanism of defense in Candida albicans and C. glabrata, two species of yeast that have become resistant to azole antifungal drugs. The researchers purified and characterized a protein called Cdr1, which is responsible for expelling these drugs from the yeast cells. The study found that Cdr1 behaves differently in the two species, suggesting that it could be a potential target for developing inhibitors to counteract drug resistance. The research was funded by various scientific organizations and has been peer-reviewed. [Extracted from the article]

Researchers from the Medical University of Bialystok in Poland have conducted a study on the molecular mechanisms of tigecycline-resistance among Enterobacterales, a type of Gram-negative bacteria. Tigecycline is an antibiotic used to treat infections caused by multidrug-resistant bacteria. The study found that the primary mechanisms of tigecycline resistance include overexpression of efflux pumps, tet genes, and outer membrane porins. The emergence and spread of pathogens resistant to last-resort therapeutic options is a major global healthcare concern. [Extracted from the article]

Researchers at Rigshospitalet have discovered that mutations in the efflux pump regulator MexZ can lead to Pseudomonas aeruginosa bacteria colonizing human airway tissue and becoming tolerant to antibiotics. These mutations, which are frequently acquired during early stages of lung infection, cause the bacteria to accumulate inside the epithelial barrier and overexpress the gene lecA, which is involved in tissue invasiveness. This overexpression is caused by an imbalance between the MexXY and MexAB efflux pumps. The study suggests that these mutations affect quorum sensing-regulated pathways, promoting tissue invasiveness and protecting the bacteria from antibiotics. [Extracted from the article]

A patent application for a microfluidic kidney-on-chip device has been filed by inventors from various locations in Massachusetts. The invention aims to address the need for better models to study drug interactions with renal tubular transporters and to test for drug-associated kidney toxicities. The device consists of a membrane with proximal tubule cells on one side and endothelial cells on the other, allowing for the measurement of transporter biomarkers and functions related to drug uptake, transport, and renal clearance. The device can be used for drug development, personalized medicine, and exploring drug-drug interactions. [Extracted from the article]

Researchers at the Department of Microbiology in Shiraz, Iran, have conducted a study on Moraxella catarrhalis, a bacterium that causes respiratory infections. The study aimed to determine the frequency of the bro beta-lactamase gene and its relationship with antibiotic resistance in Moraxella catarrhalis isolated from clinical samples. The researchers found that Moraxella catarrhalis strains with multidrug resistance carried the bro gene. Based on their findings, the researchers recommend avoiding beta-lactam antibiotics for the treatment of Moraxella catarrhalis infections, but suggest using Azithromycin, Erythromycin, Clarithromycin, and Co-amoxiclav instead. [Extracted from the article]

A study conducted by researchers at Anhui Agricultural University in China explores the effects of NDM-5, a mutant of New Delhi Metallo-b-Lactamase-1 (NDM-1), on Escherichia coli (E. coli) and the screening of interacting proteins. The study found that the introduction of NDM-5 resulted in increased resistance of E. coli to multiple b-lactam antibiotics, reduced motility, and increased biofilm formation capacity. Transcriptome sequencing revealed differentially expressed genes related to antibiotic resistance, pili, biofilm formation, and antioxidant processes. The study also identified 82 proteins that potentially interacted with NDM-5, providing insight into potential antibiotic targets and the design of novel inhibitors for carbapenem-resistant bacteria. [Extracted from the article]

This article discusses the identification of essential genes that support the fitness of Acinetobacter baumannii efflux pump overproducers in the presence of fluoroquinolone. Acinetobacter baumannii is a nosocomial pathogen that is often associated with multidrug resistance infections. The study describes a CRISPRi platform that identifies hypomorphic mutations that alter drug sensitivity in RND pump overproducers. The findings suggest that outer membrane dysfunction and defects in translation or ATP synthesis contribute to drug hypersensitivity and enhanced drug resistance in efflux overproducers. However, it is important to note that this preprint has not been peer-reviewed. [Extracted from the article]

A preprint abstract from biorxiv.org discusses the role of the cell envelope in antibiotic resistance in Burkholderia cenocepacia, a species of the Burkholderia cepacia complex (Bcc). The study identifies specific structures and processes in the cell envelope that contribute to resistance to different classes of antibiotics. For example, the polymeric O-antigen is important for resistance to cationic antibiotics, while defects in peptidoglycan precursor synthesis increase susceptibility to cycloserine. The study also highlights the role of the BpeAB-OprB efflux pump in resistance to certain drugs. The findings suggest potential targets for the development of antibiotic potentiators. [Extracted from the article]

Researchers at China Pharmaceutical University have reported new findings on the treatment of atherosclerosis, a cardiovascular disease. They have developed reactive oxygen species (ROS)-responsive and size-reducible nanoassemblies that can penetrate atherosclerotic plaque and target macrophages for drug delivery. In animal studies, these nanoassemblies reduced plaque size, lipid deposition, macrophage content, and local inflammatory factor levels. The research suggests that these nanoassemblies could be an effective strategy for atherosclerosis therapy. [Extracted from the article]

A study conducted by researchers at Islamic Azad University in Rasht, Iran, has investigated the use of ZnO nanoparticles and thymol in inhibiting the expression of biofilm and efflux pump genes in Pseudomonas aeruginosa. The researchers synthesized ZnO nanoparticles functionalized by Thiosemicarbazone nanoparticles and found that the combination of ZnO@Glu-TSC and thymol had a stronger inhibitory effect on P. aeruginosa than either agent alone. The study suggests that ZnO@Glu-TSC NPs and thymol could be a potential antibacterial treatment for P. aeruginosa strains. Further research is needed to explore the effectiveness of this combination. [Extracted from the article]

A study conducted at the National Institute of Public Health in Morelos, Mexico, has focused on the genetic characterization of ESBL-producing Escherichia coli (E. coli) isolates in Mexican hospitals. These isolates are resistant to both cephalosporins and fluoroquinolones, posing a significant threat due to antimicrobial resistance. The study found that 23 ESBL-producing E. coli isolates were positive for the qepA gene, which confers resistance to fluoroquinolones. The genetic context of the qepA gene was identified, and mating experiments showed the potential for these genetic structures to spread among Enterobacterales. The emergence of multidrug-resistant Gram-negative bacteria carrying these resistance genes is a concern for public healthcare systems. [Extracted from the article]

A study conducted by researchers at Naresuan University in Thailand has developed a novel method called the "effluxR detection assay" using multiplex digital PCR to identify efflux-associated resistance genes in Pseudomonas aeruginosa strains. Efflux pumps are a major mechanism of antimicrobial resistance in bacteria. The researchers optimized the assay conditions and successfully detected the presence of multiple efflux pump genes in P. aeruginosa. The assay showed 100% sensitivity and specificity in blind sample testing, making it a potentially valuable tool for clinical laboratory decisions and epidemiological studies. [Extracted from the article]

Keywords: San Francisco; State:California; United States; North and Central America; Antihyperlipidemic Agents; Drugs and Therapies; Genetics; Health and Medicine; Lovastatin Therapy; Naphthalenes; Pharmaceuticals; Simvastatin Therapy EN San Francisco State:California United States North and Central America Antihyperlipidemic Agents Drugs and Therapies Genetics Health and Medicine Lovastatin Therapy Naphthalenes Pharmaceuticals Simvastatin Therapy 582 582 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Drugs and Therapies - Antihyperlipidemic Agents have been presented. San Francisco, State:California, United States, North and Central America, Antihyperlipidemic Agents, Drugs and Therapies, Genetics, Health and Medicine, Lovastatin Therapy, Naphthalenes, Pharmaceuticals, Simvastatin Therapy. [Extracted from the article]

Keywords: Drugs and Therapies; Foodborne Diseases and Conditions; Gram-Positive Bacteria; Staphylococcus aureus EN Drugs and Therapies Foodborne Diseases and Conditions Gram-Positive Bacteria Staphylococcus aureus 2147 2147 1 10/09/23 20231013 NES 231013 2023 OCT 13 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Staphylococcus aureus have been published. Drugs and Therapies, Foodborne Diseases and Conditions, Gram-Positive Bacteria, Staphylococcus aureus. [Extracted from the article]

Financial supporters for this research include Biotechnology and Biological Sciences Research Council (BBSRC), Biotechnology and Biological Sciences Research Council (BBSRC), Biotechnology and Biological Sciences Research Council (BBSRC). Keywords: Norwich; United Kingdom; Europe; Drugs and Therapies; Enterobacteriaceae; Escherichia coli; Gammaproteobacteria; Genetics; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Proteobacteria; Salmonella; Salmonella enterica EN Norwich United Kingdom Europe Drugs and Therapies Enterobacteriaceae Escherichia coli Gammaproteobacteria Genetics Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Proteobacteria Salmonella Salmonella enterica 1035 1035 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Gram-Negative Bacteria - Salmonella enterica have been published. Norwich, United Kingdom, Europe, Drugs and Therapies, Enterobacteriaceae, Escherichia coli, Gammaproteobacteria, Genetics, Gram-Negative Bacteria, Gram-Negative Facultatively Anaerobic Rods, Proteobacteria, Salmonella, Salmonella enterica. [Extracted from the article]

Keywords: Ardebil; Iran; Drug Resistance; Drugs and Therapies; Gammaproteobacteria; Genetics; Gram-Negative Aerobic Bacteria; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria; Health and Medicine; Multidrug Resistance; Proteobacteria; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa EN Ardebil Iran Drug Resistance Drugs and Therapies Gammaproteobacteria Genetics Gram-Negative Aerobic Bacteria Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria Health and Medicine Multidrug Resistance Proteobacteria Pseudomonadaceae Pseudomonas Pseudomonas aeruginosa 2308 2308 1 09/04/23 20230908 NES 230908 2023 SEP 8 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Drugs and Therapies - Multidrug Resistance is now available. This study revealed that the presence and overexpression of efflux pumps are associated with the emergence of carbapenem-resistant and MDR P. aeruginosa strains." All 48 carbapenem-resistant and MDR P. aeruginosa strains harbored efflux pump-encoding genes including mexA, mexC, mexE, and mexY according to the PCR results. [Extracted from the article]

Keywords for this news article include: University of Cape Coast, Pharmaceuticals, Medical Genetics, Pharmacogenetics, Health and Medicine. Keywords: Genetics; Health and Medicine; Medical Genetics; Pharmaceuticals; Pharmacogenetics EN Genetics Health and Medicine Medical Genetics Pharmaceuticals Pharmacogenetics 1409 1409 1 08/14/23 20230818 NES 230818 2023 AUG 18 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on medical genetics. [Extracted from the article]

Keywords: Antibacterials; Antibiotics; Antimicrobials; Biological Factors; Biological Toxins; Drugs and Therapies; Genetics; Health and Medicine; Virulence Factors EN Antibacterials Antibiotics Antimicrobials Biological Factors Biological Toxins Drugs and Therapies Genetics Health and Medicine Virulence Factors 1318 1318 1 07/10/23 20230714 NES 230714 2023 JUL 14 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in antibiotics. Reports Summarize Antibiotics Research from Siksha "O" Anusandhan (Deemed to be University) (Sequencing and Characterization of M. morganii Strain UM869: A Comprehensive Comparative Genomic Analysis of Virulence, Antibiotic Resistance,...) Among them, six were associated with resistance to major antibiotic classes manifested through antibiotic target alteration (PBP3, gyrB) and antibiotic efflux (kpnH, rsmA, qacG; rsmA; CRP). [Extracted from the article]

Keywords: Achromobacter; Alcaligenaceae; Betaproteobacteria; Drugs and Therapies; Genetics; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria EN Achromobacter Alcaligenaceae Betaproteobacteria Drugs and Therapies Genetics Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria 964 964 1 07/03/23 20230707 NES 230707 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on achromobacter have been presented. Biofilm formation was measured at different carbohydrate concentrations, and the optimum biofilm formation was observed at 3M glucose and 0.5M NaCl, while the lowest results were seen at 2M maltose concentration. [Extracted from the article]

Four antimicrobial resistance gene clusters were identified in the SF190908 chromosome; one antimicrobial resistance gene cluster carried the bla(VEB) gene, which was verified as ESBL according to the CLSI and was detected in Pasteurellaceae for the first time, to the best of our knowledge. Keywords: Sichuan; People's Republic of China; Asia; China; Drugs and Therapies; Enzymes and Coenzymes; Gammaproteobacteria; Genetics; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Lactamase; Pasteurellaceae; Proteobacteria EN Sichuan People's Republic of China Asia China Drugs and Therapies Enzymes and Coenzymes Gammaproteobacteria Genetics Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Lactamase Pasteurellaceae Proteobacteria 850 850 1 05/29/23 20230602 NES 230602 2023 JUN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on Gram-Negative Bacteria - Pasteurella are discussed in a new report. [Extracted from the article]

Keywords: Antibacterials; Antibiotics; Antiinfectives; Antimicrobials; Azithromycin Therapy; Beta-Lactam Antibiotics; Betaproteobacteria; Cefixime; Cefixime Therapy; Cefotaxime; Cefotaxime Therapy; Cephalosporins; Drugs and Therapies; Erythromycin Therapy; Genetics; Gram-Negative Aerobic Bacteria; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria; Health and Medicine; Macrolide Derivatives; Neisseria gonorrhoeae; Neisseriaceae; Ophthalmic Antiinfectives; Ophthalmic Preparations; Pharmaceuticals; Proteobacteria; Sulfur Compounds; Thiazines; Third Generation Cephalosporins; World Health Organization EN Antibacterials Antibiotics Antiinfectives Antimicrobials Azithromycin Therapy Beta-Lactam Antibiotics Betaproteobacteria Cefixime Cefixime Therapy Cefotaxime Cefotaxime Therapy Cephalosporins Drugs and Therapies Erythromycin Therapy Genetics Gram-Negative Aerobic Bacteria Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria Health and Medicine Macrolide Derivatives Neisseria gonorrhoeae Neisseriaceae Ophthalmic Antiinfectives Ophthalmic Preparations Pharmaceuticals Proteobacteria Sulfur Compounds Thiazines Third Generation Cephalosporins World Health Organization 2195 2195 1 05/22/23 20230526 NES 230526 2023 MAY 26 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Neisseria gonorrhoeae is now available. Keywords for this news article include: University Indonesia, Antibacterials, Antimicrobials, Pharmaceuticals, Genetics, Thiazines, Neisseriaceae, Cefixime Therapy, Sulfur Compounds, Betaproteobacteria, Cefotaxime Therapy, Drugs and Therapies, Health and Medicine, Azithromycin Therapy, Erythromycin Therapy, Macrolide Derivatives, Neisseria gonorrhoeae, Gram-Negative Bacteria. [Extracted from the article]

Two genetic backgrounds, class 1 integrons and int-carrying integrase units, were found adjacent to the tmexC6D6-toprJ1b gene cluster and might mediate the transfer of this novel efflux pump gene cluster in Pseudomonas." Keywords: Guangzhou; People's Republic of China; Asia; Antibiotics; Antiinfectives; Drugs and Therapies; Gammaproteobacteria; Genetics; Glycylcyclines; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria; Health and Medicine; Pharmaceuticals; Proteobacteria; Pseudomonadaceae; Pseudomonas; Tigecycline Therapy EN Guangzhou People's Republic of China Asia Antibiotics Antiinfectives Drugs and Therapies Gammaproteobacteria Genetics Glycylcyclines Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria Health and Medicine Pharmaceuticals Proteobacteria Pseudomonadaceae Pseudomonas Tigecycline Therapy 717 717 1 05/22/23 20230526 NES 230526 2023 MAY 26 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Gram-Negative Bacteria - Pseudomonas have been published. [Extracted from the article]

Antineoplastics, Biomarkers, Blood Platelet Disorders, Blood Protein Disorders, Bortezomib Therapy, Cancer, Diagnostics and Screening, Drugs and Therapies, Health and Medicine, Hematologic Diseases and Conditions, Hematology, Hemic and Lymphatic Diseases and Conditions, Hemorrhagic Disorders, Hemostatic Disorders, Immunoproliferative Disorders, Lymphoproliferative Disorders, Multiple Myeloma, Myeloma, Oncology, Paraproteinemias, Pharmaceuticals, Pharmacogenetics, Risk and Prevention, Thrombocytopenia, Vascular Diseases and Conditions Keywords: Antineoplastics; Biomarkers; Blood Platelet Disorders; Blood Protein Disorders; Bortezomib Therapy; Cancer; Diagnostics and Screening; Drugs and Therapies; Health and Medicine; Hematologic Diseases and Conditions; Hematology; Hemic and Lymphatic Diseases and Conditions; Hemorrhagic Disorders; Hemostatic Disorders; Immunoproliferative Disorders; Lymphoproliferative Disorders; Multiple Myeloma; Myeloma; Oncology; Paraproteinemias; Pharmaceuticals; Pharmacogenetics; Risk and Prevention; Thrombocytopenia; Vascular Diseases and Conditions EN Antineoplastics Biomarkers Blood Platelet Disorders Blood Protein Disorders Bortezomib Therapy Cancer Diagnostics and Screening Drugs and Therapies Health and Medicine Hematologic Diseases and Conditions Hematology Hemic and Lymphatic Diseases and Conditions Hemorrhagic Disorders Hemostatic Disorders Immunoproliferative Disorders Lymphoproliferative Disorders Multiple Myeloma Myeloma Oncology Paraproteinemias Pharmaceuticals Pharmacogenetics Risk and Prevention Thrombocytopenia Vascular Diseases and Conditions 115 115 1 05/08/23 20230512 NES 230512 2023 MAY 11 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on multiple myeloma is the subject of a new report. [Extracted from the article]

Keywords: Fujian; People's Republic of China; Asia; Aminoglycoside Therapy; Antibiotics; Drugs and Therapies; Electrolytes; Enterobacteriaceae; Escherichia coli; Gram-Negative Bacteria; Health and Medicine; Hydroxides; Hydroxyl Radical; Inorganic Chemicals; Ions; Pharmaceuticals; Proteobacteria; Reactive Oxygen Species EN Fujian People's Republic of China Asia Aminoglycoside Therapy Antibiotics Drugs and Therapies Electrolytes Enterobacteriaceae Escherichia coli Gram-Negative Bacteria Health and Medicine Hydroxides Hydroxyl Radical Inorganic Chemicals Ions Pharmaceuticals Proteobacteria Reactive Oxygen Species 690 690 1 05/08/23 20230512 NES 230512 2023 MAY 12 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Gram-Negative Bacteria - Escherichia coli. Carbonyl cyanide m-chlorophenylhydrazine (CCCP), a well-known protonophore for dissipating proton motive force (PMF), has been widely used to block the PMFdependent uptake of aminoglycoside antibiotics and thus suppress aminoglycoside lethality.". [Extracted from the article]

Keywords: Antifungals; Drugs and Therapies; Enterobacteriaceae; Gammaproteobacteria; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Health and Medicine; Pharmaceuticals; Phenyl Ethers; Proteobacteria; Serratia; Triclosan; Triclosan Therapy EN Antifungals Drugs and Therapies Enterobacteriaceae Gammaproteobacteria Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Health and Medicine Pharmaceuticals Phenyl Ethers Proteobacteria Serratia Triclosan Triclosan Therapy 1889 1889 1 05/02/23 20230505 NES 230505 2023 MAY 5 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on serratia. Antifungals, Drugs and Therapies, Enterobacteriaceae, Gammaproteobacteria, Gram-Negative Bacteria, Gram-Negative Facultatively Anaerobic Rods, Health and Medicine, Pharmaceuticals, Phenyl Ethers, Proteobacteria, Serratia, Triclosan, Triclosan Therapy. [Extracted from the article]

According to news reporting originating from Rasht, Iran, by NewsRx correspondents, research stated, "Due to the increasing multi-drug resistance, infections caused by Staphylococcus aureus is regarded as an important health threat. Keywords: Rasht; Iran; Alternative Medicine; Bacillales; Cyanobacteria; Drug Resistance; Drugs and Therapies; Emerging Technologies; Endospore-Forming Bacteria; Genetics; Gram-Positive Bacteria; Gram-Positive Cocci; Gram-Positive Endospore-Forming Rods; Health and Medicine; Nanocomposites; Nanoparticles; Nanotechnology; Pharmaceuticals; Spirulina; Spirulina Therapy; Staphylococcaceae; Staphylococcus; Staphylococcus aureus EN Rasht Iran Alternative Medicine Bacillales Cyanobacteria Drug Resistance Drugs and Therapies Emerging Technologies Endospore-Forming Bacteria Genetics Gram-Positive Bacteria Gram-Positive Cocci Gram-Positive Endospore-Forming Rods Health and Medicine Nanocomposites Nanoparticles Nanotechnology Pharmaceuticals Spirulina Spirulina Therapy Staphylococcaceae Staphylococcus Staphylococcus aureus 1827 1827 1 04/24/23 20230428 NES 230428 2023 APR 28 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Gram-Positive Bacteria - Staphylococcus aureus. [Extracted from the article]

Adenocarcinoma, Apoptosis, Cancer, Cellular Physiology, Colon Cancer, Drugs and Therapies, Gastroenterology, Health and Medicine, Oncology Keywords: Adenocarcinoma; Apoptosis; Cancer; Cellular Physiology; Colon Cancer; Drugs and Therapies; Gastroenterology; Health and Medicine; Oncology EN Adenocarcinoma Apoptosis Cancer Cellular Physiology Colon Cancer Drugs and Therapies Gastroenterology Health and Medicine Oncology 1654 1654 1 03/24/23 20230228 NES 230228 2023 FEB 27 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on colon cancer are presented in a new report. [Extracted from the article]

Keywords: Antibacterials; Antibiotics; Antimicrobials; Bacillales; Drugs and Therapies; Endospore-Forming Bacteria; Genetics; Gram-Positive Bacteria; Gram-Positive Cocci; Gram-Positive Endospore-Forming Rods; Health and Medicine; Staphylococcaceae; Staphylococcus; Staphylococcus aureus EN Antibacterials Antibiotics Antimicrobials Bacillales Drugs and Therapies Endospore-Forming Bacteria Genetics Gram-Positive Bacteria Gram-Positive Cocci Gram-Positive Endospore-Forming Rods Health and Medicine Staphylococcaceae Staphylococcus Staphylococcus aureus 1696 1696 1 03/24/23 20230224 NES 230224 2023 FEB 24 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Staphylococcus aureus is now available. Antibacterials, Antibiotics, Antimicrobials, Bacillales, Drugs and Therapies, Endospore-Forming Bacteria, Genetics, Gram-Positive Bacteria, Gram-Positive Cocci, Gram-Positive Endospore-Forming Rods, Health and Medicine, Staphylococcaceae, Staphylococcus, Staphylococcus aureus. [Extracted from the article]

Keywords: Antibiotics; Antiinfectives; Colistin; Colistin Therapy; Drugs and Therapies; Enterobacteriaceae; Gammaproteobacteria; Genetics; Glycylcyclines; Gram-Negative Bacteria; Gram-Negative Facultatively Anaerobic Rods; Health and Medicine; Klebsiella; Klebsiella pneumoniae; Membrane Proteins; Pharmaceuticals; Polymyxins; Pore Forming Cytotoxic Proteins; Proteobacteria; Tigecycline Therapy EN Antibiotics Antiinfectives Colistin Colistin Therapy Drugs and Therapies Enterobacteriaceae Gammaproteobacteria Genetics Glycylcyclines Gram-Negative Bacteria Gram-Negative Facultatively Anaerobic Rods Health and Medicine Klebsiella Klebsiella pneumoniae Membrane Proteins Pharmaceuticals Polymyxins Pore Forming Cytotoxic Proteins Proteobacteria Tigecycline Therapy 2923 2923 1 03/24/23 20230217 NES 230217 2023 FEB 17 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Klebsiella pneumoniae have been presented. For more information on this research see: Emergence of high-level colistin resistance mediated by multiple determinants, including mcr-1.1, mcr-8.2 and crrB mutations, combined with tigecycline resistance in an ST656 Klebsiella pneumoniae. [Extracted from the article]

Studies from Siksha "O" Anusandhan (Deemed to be University) Reveal New Findings on Enterobacter (Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors) According tonews originating from Bhubaneswar, India, by NewsRx editors, theresearch stated, "Primary apical periodontitis occurs due to variousinsults to the dental pulp including microbial infections, physical andiatrogenic trauma, whereas inadequate elimination of intraradicularinfection during root canal treatment may lead to secondary apicalperiodontitis. Gram-Negative Bacteria - Enterobacter Investigators discuss new findings in enterobacter. [Extracted from the article]