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Researchers at the University of Georgia have developed Coagulo-Net, a novel approach that combines deep neural networks with the understanding of blood coagulation processes to enhance mathematical models of the blood coagulation cascade. This new method aims to efficiently infer unknown model parameters and dynamics of species based on sparse measurement data and noise. The research showcases the potential of Coagulo-Net to advance computational modeling in the study of blood coagulation, potentially improving research methodologies and the development of new therapies for patients with coagulation disorders. [Extracted from the article]

Researchers from the Agricultural University of Athens have conducted a metagenomic analysis of hot spring soil to identify a novel thermostable enzybiotic for the treatment of bacterial infections. The study focused on the misuse of antibiotics leading to antibiotic-resistant bacterial pathogens, emphasizing the need for innovative antimicrobials. The identified enzyme, Ami1, exhibited strong bactericidal and antimicrobial activity against various bacterial pathogens, particularly Staphylococcus aureus and Staphylococcus epidermidis. The research suggests that Ami1 has the potential to be further developed as a broad-spectrum antimicrobial agent for effective treatment of bacterial infections. [Extracted from the article]

Researchers at the University of Georgia conducted a study on the effects of lipophilic bisphosphonates on mice chronically infected with Toxoplasma gondii. The study found that these compounds reduced the cyst burden in the brains of infected mice and ameliorated hyperactivity during chronic infection. The research, supported by the NIH, highlights the potential of lipophilic bisphosphonates in controlling the development of chronic stages of T. gondii. For more information, the full study can be accessed in the journal mBio. [Extracted from the article]

Researchers from the National and Kapodistrian University of Athens conducted a systematic review of literature on the hemostatic profile in neonates with intrauterine growth restriction (IUGR). The study found that IUGR neonates often exhibit thrombocytopenia and prolonged coagulation tests, but data on coagulation factors are limited and conflicting. Despite laboratory abnormalities, no clear correlation was found between these findings and clinical bleeding or thrombosis. The researchers concluded that further studies are needed to better understand hemostasis in IUGR neonates and guide targeted therapeutic interventions. [Extracted from the article]

Researchers from the National and Kapodistrian University of Athens have developed a new assay for quantifying phages against multidrug-resistant gram-negative pathogens. The assay, called the single-layer spot assay (SLA-spot), is cheaper, faster, and easier to perform compared to the standard double-layer agar (DLA) assay. The SLA-spot assay generated similar phage concentrations as the DLA-spread assay and produced same-day results. This research provides an alternative method for quantifying phages and may have implications for phage therapy. [Extracted from the article]

Researchers from the University of Georgia have developed a new antimalarial agent called l-BHDU. This compound has shown promising activity against the varicella-zoster virus (VZV) and could potentially be used to treat chickenpox, shingles, and herpes simplex virus 1 (HSV-1) infections. The researchers have also developed a prodrug of l-BHDU, called POM-l-BHDU-MP, which has demonstrated enhanced pharmacokinetic and antiviral properties. The synthesis of l-BHDU and its prodrug was achieved through an efficient and practical methodology that eliminates the need for expensive chiral chromatography. This research provides new avenues for the development and study of nucleosides derived from l- & d-dioxolane. [Extracted from the article]

Researchers at the National Technical University of Athens have conducted a study on the interactions of a chemotherapy medication called berubicin with double-stranded DNA sequences and cyclodextrins in an aqueous environment. The study used molecular dynamics simulations to analyze the drug in both neutral and protonated states. The researchers investigated the thermodynamic description of the berubicin-DNA and berubicin-cyclodextrin complexes and analyzed their structural and geometrical properties. The study also compared the bound states of berubicin with cyclodextrins commonly used for drug delivery purposes. This research provides valuable insights into the role of charge and complexation in the behavior of anthracycline drugs. [Extracted from the article]

A report from the National and Kapodistrian University of Athens discusses research on machine learning in pharmacokinetics. The researchers developed a method to address model misspecification in population pharmacokinetics by using machine learning to model residual unexplained variability. The methodology was tested in a study of ropinirole and was found to generate realistic virtual patient profiles and quantify the extent of model misspecification. The research concludes that the greater the extent of variability explained by the machine learning model, the higher the degree of model misspecification in the original model. [Extracted from the article]

A recent study conducted at the University of Georgia has explored the use of bioinspired superhydrophobic surfaces with silver and nitric oxide-releasing capabilities to prevent device-associated infections and thrombosis. The researchers integrated superhydrophobicity with nitric oxide release to create a functional polymeric material that possesses anti-thrombogenic and antimicrobial characteristics. The surfaces demonstrated a significant reduction in viable adhered bacteria and platelets compared to controls, without any cytotoxic effects on fibroblast cells. This innovative approach has the potential to minimize complications associated with medical devices without the need for conventional systemic anticoagulation and antibiotic treatments. [Extracted from the article]

A study conducted by the European Center for Disease Prevention and Control has found that Candida auris, a fungal infection, has been increasingly detected among inpatients in Greek healthcare facilities. The study involved 11 hospitals in the Attica region and identified 20 cases of invasive infection and 25 cases of colonization. The research highlights the importance of surveillance, infection control measures, and understanding local epidemiology in preventing the spread of Candida auris in healthcare settings. The study also found that the infection had a high mortality rate and resistance to certain antifungal drugs. [Extracted from the article]

A recent study conducted by researchers at the University of Georgia has found that defects in the pgsA gene contribute to increased membrane fluidity and cell wall thickening in Staphylococcus aureus, a bacterium that is often resistant to antibiotics. The study focused on daptomycin, a last-resort antimicrobial therapy used to treat infections caused by drug-resistant strains of S. aureus. The researchers discovered that mutations in the pgsA gene led to changes in the composition of the bacterial membrane, making it more resistant to daptomycin. These findings provide valuable insights into the mechanisms of antibiotic resistance in S. aureus and could potentially inform the development of new treatment strategies. [Extracted from the article]

A recent report from the University of Georgia discusses the supply-side constraints that are limiting the availability of buprenorphine, a medication used for opioid use disorder. The current restrictions on distribution and dispensing practices of pharmaceutical wholesalers and pharmacies, combined with opioid litigation and federal regulations, are hindering access to this medication. The researchers propose a solution in the form of a Drug Enforcement Administration (DEA) guidance letter, which could provide clarity and assurance to distributors and pharmacies regarding the distribution of buprenorphine. This strategy aims to improve access to medication for opioid use disorder by addressing supply-side limitations. [Extracted from the article]

A study conducted at Army Share Fund Hospital in Athens, Greece, explores the use of apheresis as a modern medical approach in which plasma or cellular components are separated from whole blood. Apheresis can be used for diagnostic or therapeutic purposes, with therapeutic apheresis (TA) being applied in various medical specialties, including the Intensive Care Unit (ICU). The most commonly used method in the ICU is Therapeutic Plasma Exchange (TPE), which is considered a first-line therapy for certain conditions. The study aims to describe the characteristics, safety, and clinical impact of apheresis methods used in ICUs. [Extracted from the article]

Researchers from the University of Georgia have conducted a study on the use of bile acid-targeted hyaluronic acid nanoparticles to enhance the oral absorption of deferoxamine (DFO), a drug used to treat hemochromatosis. The study found that the nanoparticles improved the permeation of DFO and were less cytotoxic to cells compared to the free drug. Additionally, the conjugation of DFO to the nanoparticles did not compromise its iron chelation efficiency. This research suggests that bile acid-targeted hyaluronic acid nanoparticles may be a promising approach to improve the oral delivery of DFO. [Extracted from the article]

A study conducted by researchers at Ohio University examined the availability of transitional opioid programs in rural and urban hospitals in the United States. These programs, which provide screening, medications for opioid use disorder, and addiction consult services, are considered the gold standard for opioid-related interventions. The study found that while rural hospitals did not have lower odds of screening for opioid use disorder or other substance use disorders compared to urban hospitals, they were less likely to offer addiction consult services or medications for opioid use disorder. The researchers concluded that efforts should be made to support rural hospital adoption of these evidence-based interventions to address rural-urban disparities in health outcomes related to opioid use disorder. [Extracted from the article]

A recent report from the University of Georgia examines the efforts of Single State Agencies (SSAs) in addressing the opioid epidemic in the United States. The study found that SSAs play a crucial role in allocating funds and implementing initiatives to combat the crisis. The research highlights the importance of expanding access to treatment for opioid-related overdose, naloxone distribution, and recovery support services. However, there is limited adoption of efforts to expand access to medications for opioid use disorder and harm reduction services. The study also raises concerns about the sustainability of funding for these initiatives in the future. [Extracted from the article]

A recent study conducted by researchers at Ohio University highlights the underutilization of buprenorphine, a highly effective medication for opioid use disorder (OUD), by primary care professionals (PCPs) in rural communities. The study found that current training efforts on buprenorphine prescribing are inadequate for rural PCPs, who face unique challenges and barriers. Participants suggested tailored training strategies for rural practice, including content specific to rural settings, rural trainers, and addressing rural-specific barriers. The research emphasizes the need for improved accessibility and acceptability of buprenorphine training to better support rural PCPs in combating the opioid epidemic. [Extracted from the article]

A recent report from HYGEIA Hospital in Athens, Greece discusses the management strategies for atypical parkinsonism, which includes progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system atrophy (MSA). These disorders have a poor prognosis and present with a variety of symptoms. The report emphasizes the importance of a holistic and multidisciplinary approach to treatment, including both pharmacological and non-pharmacological interventions. It also addresses important clinical practice questions such as breaking the news, palliative care, and end-of-life issues. The research provides an overview of the management of atypical parkinsonism from diagnosis to advanced stages. [Extracted from the article]

A recent study conducted by researchers at the University of Georgia has shed light on the biological role of Rufomycin, a class of cyclic heptapeptides that have shown promise in treating Mycobacterium tuberculosis infections. The study focused on RufO, an enzyme believed to be involved in the formation of a specific amino acid called 3-nitro-tyrosine. However, the researchers found that RufO does not exhibit the typical structural changes and redox potential associated with similar enzymes. The study suggests that the nitration of amino acids may occur during or after the assembly of the peptides. This research provides valuable insights into the biosynthesis of nonribosomal peptides. [Extracted from the article]

A recent study conducted by researchers at the National & Kapodistrian University in Athens, Greece, explored the relationship between allelic variations of the follicle-stimulating hormone receptor (FSHr) gene and controlled ovarian stimulation (COS) in assisted reproductive technologies (ART). The study analyzed 11 studies involving 4,343 patients with Asn680Ser polymorphisms of the FSHr gene. The results showed that patients with different genotypes had varying responses to COS, with differences in hormone levels and embryo transfer outcomes. However, the study concluded that further research is needed to develop an algorithm that combines genetic analysis with hormonal profiles to personalize treatment. [Extracted from the article]

A study conducted by researchers at the University of Georgia explores the impact of chronic hypoxia on muscle regeneration and the underlying molecular mechanisms. The study found that chronic hypoxia leads to muscle atrophy and weakness, along with impaired muscle regeneration. Stabilization of the HIF-2 alpha protein in muscle stem cells (MuSCs) under chronic hypoxia hindered MuSC proliferation, while ablation of HIF-2 alpha mitigated the adverse effects of chronic hypoxia on muscle regeneration. The study suggests that pharmacological interventions with HIF-2 alpha or ACE inhibitors may be beneficial in alleviating chronic hypoxia-associated muscle atrophy and weakness by improving muscle regeneration. [Extracted from the article]

Researchers at Ohio University have made significant progress in developing antagonists of human growth hormone (hGH) action. They have created a new set of protein antagonists that can bind to both the hGH receptor (hGHR) and the prolactin receptor. These antagonists have shown potential for multiple clinical applications related to GH-associated pathologies, including cancer treatment. The research was funded by InfinixBio LLC, the State of Ohio's Eminent Scholar Program, and the Edison Biotechnology Institute at Ohio University. [Extracted from the article]

A recent study conducted at the University of Georgia examined the impact of a critical care pharmacy elective (CCPE) on student performance in other courses in the Doctor of Pharmacy curriculum. The study found that students who completed the CCPE were more likely to demonstrate outstanding performance in Integrated Patient Cases (IPC), but not in the Pharmacotherapy courses. The researchers suggest that practicing clinical reasoning earlier in the curriculum may help students build up to effective and efficient clinical decision-making. The implications of course structure on student performance should be further explored. [Extracted from the article]

A recent study conducted by researchers from the University of Georgia examined the counseling practices of community pharmacists regarding naloxone, an opioid antagonist used to reverse opioid overdoses. The study found that while pharmacists recognized the importance of naloxone counseling in preventing opioid-related overdose deaths, they also expressed concerns about offending patients. The researchers identified various factors that influenced pharmacists' provision of naloxone counseling, including regulatory agencies, managers, news/media, patients, and doctors. The study suggests that addressing barriers such as reimbursement issues, high costs of naloxone, and increasing patient awareness could enhance pharmacists' naloxone counseling. [Extracted from the article]

A recent study conducted by researchers from National & Kapodistrian University in Athens, Greece, focused on the management of neurological complications related to aneurysmal subarachnoid hemorrhage (aSAH). The study aimed to review the most recent literature and assess treatment schemes for aSAH neurological complications in adults. The researchers found six stepwise algorithms for treating cerebral vasospasm-delayed cerebral ischemia (DCI), but no algorithm for managing other neurological complications of aSAH. The study concluded that more research is needed to stratify current treatment algorithms based on the quality of their evidence. Despite advances in securing a ruptured aneurysm, there is still a high rate of neurological deficit and mortality in aSAH cases. [Extracted from the article]

Researchers from the National and Kapodistrian University of Athens have developed a new agar-based screening method for testing the susceptibility of Trichophyton spp. to antifungal drugs. The method was validated using molecularly characterized isolates and showed optimal growth conditions and stability over time. It successfully detected non-wild type Trichophyton spp. strains, making it a useful tool for routine diagnostic laboratories. This research contributes to addressing the emerging global public health issue of resistance in dermatophytes. [Extracted from the article]

A study conducted by the University of Georgia has found that reward processing impairments are associated with negative symptoms in individuals with severe mental illnesses. The study examined the hypothesis that these mixed findings may be due to multiple reward processing pathways that cut across diagnostic boundaries and phases of illness. The researchers identified three clusters with different reward processing profiles, including global reward processing deficits, selective impairments in hedonic reactivity alone, and preserved reward processing. The findings suggest that personalized treatments targeting specific reward processing pathways may help improve symptom trajectories in individuals with severe mental illnesses. [Extracted from the article]

Keywords: Athens; Greece; Europe; Drug Research; Anorexigenic Agent; Caffeine; Central Nervous System Stimulants; Epidemiology; Health and Medicine; Phosphodiesterase Inhibitors EN Athens Greece Europe Drug Research Anorexigenic Agent Caffeine Central Nervous System Stimulants Epidemiology Health and Medicine Phosphodiesterase Inhibitors 1025 1025 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on Drug Research is the subject of a report. Keywords for this news article include: Athens, Greece, Europe, Drug Research, Anorexigenic Agent, Caffeine, Central Nervous System Stimulants, Epidemiology, Health and Medicine, Phosphodiesterase Inhibitors, National and Kapodistrian University of Athens. [Extracted from the article]

The carbohydrate recognition domain and stalk region of the C-type lectin pathogen receptor Dectin-3 (MCL, CLEC4D) were coupled to a lipid carrier (a) and, via its lipid moiety, inserted into an Amphotericin B-loaded, red fluorescent liposome, producing a DectiSome (b)." Keywords: Athens; State:Georgia; United States; North and Central America; Biotechnology; Health and Medicine; Liposomes EN Athens State:Georgia United States North and Central America Biotechnology Health and Medicine Liposomes 3172 3172 1 10/30/23 20231103 NES 231103 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Biotechnology - Liposomes are presented in a new report. [Extracted from the article]

Keywords: Athens; Greece; Europe; Business; Cardiology; Cardiovascular Diseases and Conditions; Drugs and Therapies; Empagliflozin Therapy; Health Information Technology Companies; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Failure; IQVIA; Pharmaceuticals; Sodium-Glucose Transporter 2 Inhibitors EN Athens Greece Europe Business Cardiology Cardiovascular Diseases and Conditions Drugs and Therapies Empagliflozin Therapy Health Information Technology Companies Health and Medicine Heart Disease Heart Disorders and Diseases Heart Failure IQVIA Pharmaceuticals Sodium-Glucose Transporter 2 Inhibitors 370 370 1 10/30/23 20231103 NES 231103 2023 OCT 30 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Heart Disorders and Diseases - Heart Failure are presented in a new report. Keywords for this news article include: Athens, Greece, Europe, Business, Cardiology, Cardiovascular Diseases and Conditions, Drugs and Therapies, Empagliflozin Therapy, Health Information Technology Companies, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Failure, IQVIA, Pharmaceuticals, Sodium-Glucose Transporter 2 Inhibitors, IQVIA. [Extracted from the article]

Keywords for this news article include: Athens, Greece, Europe, Pharmaceutics, Drugs and Therapies, National Center of Scientific Research. Greece, Europe, Pharmaceutics, Drugs and Therapies, Athens Keywords: Athens; Greece; Europe; Pharmaceutics; Drugs and Therapies EN Athens Greece Europe Pharmaceutics Drugs and Therapies 1206 1206 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Drugs and Therapies - Pharmaceutics is now available. [Extracted from the article]

Keywords: Athens; Greece; Europe; Cardiovascular Agents; Diuretics; Drugs and Therapies; Health and Medicine; Mannitol; Mannitol Therapy; Pharmaceuticals; Pharmacokinetics; Pharmacology; Sugar Alcohols EN Athens Greece Europe Cardiovascular Agents Diuretics Drugs and Therapies Health and Medicine Mannitol Mannitol Therapy Pharmaceuticals Pharmacokinetics Pharmacology Sugar Alcohols 1267 1267 1 10/09/23 20231013 NES 231013 2023 OCT 13 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Drugs and Therapies - Mannitol Therapy. Athens, Greece, Europe, Cardiovascular Agents, Diuretics, Drugs and Therapies, Health and Medicine, Mannitol, Mannitol Therapy, Pharmaceuticals, Pharmacokinetics, Pharmacology, Sugar Alcohols. [Extracted from the article]

Athens, State:Georgia, United States, North and Central America, Antioxidants, Drugs and Therapies, Protective Agents Keywords: Athens; State:Georgia; United States; North and Central America; Antioxidants; Drugs and Therapies; Protective Agents EN Athens State:Georgia United States North and Central America Antioxidants Drugs and Therapies Protective Agents 609 609 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Drugs and Therapies - Antioxidants. [Extracted from the article]

Keywords: Athens; State:Georgia; United States; North and Central America; Amides; Aminopenicillins; Ampicillin Therapy; Antibacterials; Antibiotics; Antiinfectives; Antimicrobials; Bacterial Infections and Mycoses; Beta-Lactam Antibiotics; Chemicals; Drugs and Therapies; Health and Medicine; Nitric Oxide; Nitrogen Oxides; Organic Chemicals; Penicillin G Therapy; Penicillins; Pharmaceuticals; Reactive Nitrogen Species; Sulfur Compounds EN Athens State:Georgia United States North and Central America Amides Aminopenicillins Ampicillin Therapy Antibacterials Antibiotics Antiinfectives Antimicrobials Bacterial Infections and Mycoses Beta-Lactam Antibiotics Chemicals Drugs and Therapies Health and Medicine Nitric Oxide Nitrogen Oxides Organic Chemicals Penicillin G Therapy Penicillins Pharmaceuticals Reactive Nitrogen Species Sulfur Compounds 358 358 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Bacterial Infections and Mycoses is now available. For more information on this research see: Antimicrobial Efficacy of a Nitric Oxide-releasing Ampicillin Conjugate Catheter Lock Solution On Clinically-isolated Antibiotic-resistant Bacteria. [Extracted from the article]

Keywords: Athens; Greece; Europe; Amyloid; Caenorhabditis elegans; Drugs and Therapies; Life Science Research; Peptides and Proteins; Proteins; Rhabditida; Rhabditidae EN Athens Greece Europe Amyloid Caenorhabditis elegans Drugs and Therapies Life Science Research Peptides and Proteins Proteins Rhabditida Rhabditidae 1374 1374 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Peptides and Proteins - Amyloid is now available. Keywords for this news article include: Athens, Greece, Europe, Amyloid, Caenorhabditis elegans, Drugs and Therapies, Life Science Research, Peptides and Proteins, Proteins, Rhabditida, Rhabditidae, National Hellenic Research Foundation. [Extracted from the article]

Keywords: Athens; State:Ohio; United States; North and Central America; Gastroenterology; Glucagon; Health and Medicine; Hormones; Intercellular Signaling Peptides and Proteins; Pancreas; Parathyroid Hormone; Parathyroid Hormone-Related Proteins; Peptide Hormones; Peptide Proteins; Proglucagon; Proinsulin EN Athens State:Ohio United States North and Central America Gastroenterology Glucagon Health and Medicine Hormones Intercellular Signaling Peptides and Proteins Pancreas Parathyroid Hormone Parathyroid Hormone-Related Proteins Peptide Hormones Peptide Proteins Proglucagon Proinsulin 897 897 1 09/04/23 20230908 NES 230908 2023 SEP 8 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Intercellular Signaling Peptides and Proteins - Parathyroid Hormone-Related Proteins have been published. Athens, State:Ohio, United States, North and Central America, Gastroenterology, Glucagon, Health and Medicine, Hormones, Intercellular Signaling Peptides and Proteins, Pancreas, Parathyroid Hormone, Peptide Hormones, Peptide Proteins, Proglucagon, Proinsulin, Parathyroid Hormone-Related Proteins. [Extracted from the article]

According to news reporting originating from Athens, Greece, by NewsRx correspondents, research stated, "In this work, a simple, fast, and sensitive voltammetric method for the trace determination of the alkaloid drug colchicine (Colc) using a 3D-printed device is described. Keywords: Athens; Greece; Europe; Antigout Agents; Chemicals; Colchicine Therapy; Drugs and Therapies; Electrochemicals; Health and Medicine; Pharmaceuticals EN Athens Greece Europe Antigout Agents Chemicals Colchicine Therapy Drugs and Therapies Electrochemicals Health and Medicine Pharmaceuticals 2637 2637 1 08/28/23 20230901 NES 230901 2023 SEP 1 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Drugs and Therapies - Antigout Agents are presented in a new report. Keywords for this news article include: Athens, Greece, Europe, Antigout Agents, Chemicals, Colchicine Therapy, Drugs and Therapies, Electrochemicals, Health and Medicine, Pharmaceuticals, National and Kapodistrian University of Athens. [Extracted from the article]

Keywords: Athens; Greece; Europe; Emerging Technologies; Nanomicelles; Nanotechnology EN Athens Greece Europe Emerging Technologies Nanomicelles Nanotechnology 1358 1358 1 08/28/23 20230901 NES 230901 2023 SEP 1 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on Nanotechnology - Nanomicelles. At pH = 6.8, without Pluronic((R)) F-127, the beads showed an enhanced swelling ratio for the first four hours, which was even higher in the medium-viscosity alginate beads. [Extracted from the article]

Keywords: Athens; Greece; Europe; Antineoplastics; Cancer; Chemoembolization; Colon Cancer; Colorectal Research; Drugs and Therapies; Enzyme Inhibitors; Gastroenterology; Health and Medicine; Irinotecan Therapy; Oncology; Parasympathomimetic; Pharmaceuticals; Prodrugs; Radiation-Sensitizing Agents EN Athens Greece Europe Antineoplastics Cancer Chemoembolization Colon Cancer Colorectal Research Drugs and Therapies Enzyme Inhibitors Gastroenterology Health and Medicine Irinotecan Therapy Oncology Parasympathomimetic Pharmaceuticals Prodrugs Radiation-Sensitizing Agents 1296 1296 1 08/14/23 20230818 NES 230818 2023 AUG 15 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Oncology - Colon Cancer have been published. Athens, Greece, Europe, Antineoplastics, Cancer, Chemoembolization, Colon Cancer, Colorectal Research, Drugs and Therapies, Enzyme Inhibitors, Gastroenterology, Health and Medicine, Irinotecan Therapy, Oncology, Parasympathomimetic, Pharmaceuticals, Prodrugs, Radiation-Sensitizing Agents. [Extracted from the article]

Keywords: Athens; Greece; Europe; Drug Development; Drug Encapsulation; Drugs and Therapies; Emerging Technologies; Health and Medicine; Nanostructural; Nanostructures; Nanotechnology EN Athens Greece Europe Drug Development Drug Encapsulation Drugs and Therapies Emerging Technologies Health and Medicine Nanostructural Nanostructures Nanotechnology 2305 2305 1 08/14/23 20230818 NES 230818 2023 AUG 18 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on Nanotechnology - Nanostructures are discussed in a new report. This study aims to produce mixed micelle nanostructures from a linear triblock copolymer and a hyperbranched random copolymer, and is able to be loaded with the weakly water-soluble drugs curcumin and indomethacin.". [Extracted from the article]

Keywords: Athens; State:Georgia; United States; North and Central America; Life Science; Drugs and Therapies; Genetics EN Athens State:Georgia United States North and Central America Life Science Drugs and Therapies Genetics 2162 2162 1 07/17/23 20230721 NES 230721 2023 JUL 21 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Life Science have been published. The news reporters obtained a quote from the research from the University of Georgia, "We identified clusters of genes involved in MIA biosynthesis on the eight C. roseus chromosomes and extensive gene duplication of MIA pathway genes. Athens, State:Georgia, United States, North and Central America, Life Science, Drugs and Therapies, Genetics. [Extracted from the article]

Rbpj-deficient (mutant) brain ECs acquired abnormally rounded shape (with no change to cell area), altered basement membrane dynamics, and increased endothelial cell density along arteriovenous shunts, compared to controls, suggesting impaired remodeling of neonatal brain vasculature. Keywords: Athens; State:Ohio; United States; North and Central America; Arteriovenous Malformation; Arteriovenous Malformations; Cardiovascular Abnormalities; Cardiovascular Diseases and Conditions; Cell Nucleus Structures; Chromatin; Chromosome Structures; Congenital Abnormalities; Endothelial Cells; Enzymes and Coenzymes; GTPase; Health and Medicine; Intranuclear Space; Nucleoproteins; Proteins; Vascular Malformations EN Athens State:Ohio United States North and Central America Arteriovenous Malformation Arteriovenous Malformations Cardiovascular Abnormalities Cardiovascular Diseases and Conditions Cell Nucleus Structures Chromatin Chromosome Structures Congenital Abnormalities Endothelial Cells Enzymes and Coenzymes GTPase Health and Medicine Intranuclear Space Nucleoproteins Proteins Vascular Malformations 349 349 1 07/17/23 20230721 NES 230721 2023 JUL 17 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Cardiovascular Diseases and Conditions - Arteriovenous Malformations is now available. [Extracted from the article]

Keywords: Athens; Greece; Europe; Health and Medicine; Drugs and Therapies; Epidemiology EN Athens Greece Europe Health and Medicine Drugs and Therapies Epidemiology 397 397 1 06/19/23 20230623 NES 230623 2023 JUN 23 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Health and Medicine - Epidemiology have been presented. Our news editors obtained a quote from the research from the National and Kapodistrian University of Athens, "We compared CD4 cell-count trends before disengagement from care and after ART reinitiation. [Extracted from the article]

Keywords: Athens; State:Georgia; United States; North and Central America; Antiinfectives; Antimalarial Agents; Antineoplastics; Chickenpox; Drugs and Therapies; Health and Medicine; Infectious Diseases and Conditions; Pharmaceuticals; Prodrugs; Tetracyclines; Uracil Therapy; Varicella; Varicella-Zoster Virus; Viral; Virology EN Athens State:Georgia United States North and Central America Antiinfectives Antimalarial Agents Antineoplastics Chickenpox Drugs and Therapies Health and Medicine Infectious Diseases and Conditions Pharmaceuticals Prodrugs Tetracyclines Uracil Therapy Varicella Varicella-Zoster Virus Viral Virology 958 958 1 06/05/23 20230609 NES 230609 2023 JUN 9 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on Infectious Diseases and Conditions - Chickenpox are discussed in a new report. The phosphate ester prodrugs POM-L-BHDU-MP and POC-L-BHDU-MP had a significant anti-VZV activity with EC50 values of 0.035 and 0.034 mu M, respectively, and no cellular toxicity (CC50 > 100 mu M) was detected.". [Extracted from the article]

Inclusion criteria were as follows: peer-reviewed empirical research conducted in the U.S. from January 2010 through February 2022; published in English; and addressed a) pharmacists' naloxone services and/or b) KAB related to the implementation of naloxone services. New Antidotes Study Findings Have Been Reported by Investigators at University of Georgia (Pharmacists? The objectives of this systematic review were to a) identify pharmacists' naloxone services and their outcomes, and b) examine knowledge, attitudes, and barriers (KAB) related to naloxone service provision in noncommunity pharmacy settings. [Extracted from the article]

Athens, Greece, Europe, Obesity Fitness and Wellness, Carboxylic Acids, Drugs and Therapies, Hydroxamic Acids, Hydroxy Acids, Hydroxylamines, Organic Chemicals, Quaternary Ammonium Compounds Keywords: Athens; Greece; Europe; Obesity Fitness and Wellness; Carboxylic Acids; Drugs and Therapies; Hydroxamic Acids; Hydroxy Acids; Hydroxylamines; Organic Chemicals; Quaternary Ammonium Compounds EN Athens Greece Europe Obesity Fitness and Wellness Carboxylic Acids Drugs and Therapies Hydroxamic Acids Hydroxy Acids Hydroxylamines Organic Chemicals Quaternary Ammonium Compounds 556 556 1 04/10/23 20230414 NES 230414 2023 APR 14 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Obesity, Fitness and Wellness. [Extracted from the article]