20,831 results
Search Results
2. [The application of the non-woven fabric and filter paper "sandwich" fixation method in preventing the separation of the mucosal layer and muscular layer in mouse colon histopathological sections].
- Author
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Shen L, Li YT, Xu MY, Liu GY, Zhang XW, Cheng Y, Zhu GQ, Zhang M, Wang L, Zhang XF, Zuo LG, Geng ZJ, Li J, Wang YY, and Song X
- Subjects
- Animals, Mice, Colon, Histological Techniques
- Published
- 2023
- Full Text
- View/download PDF
3. [Application of paper-based microfluidics in point-of-care testing].
- Author
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Xu J, Zhang Y, Su X, Zhang S, and Ge S
- Subjects
- Humans, Diagnostic Tests, Routine methods, Microfluidic Analytical Techniques instrumentation, Paper, Point-of-Care Testing
- Abstract
Point-of-care testing (POCT) is a test method performed on the sampling site or patient bedside. Accurate results can be achieved rapidly by the application of portable analytical instruments and compatible reagents. It has been widely used in the field of in vitro diagnosis (IVD). Paper-based microfluidics technology has great potential in developing POCT due to its advantages in low cost, simple operation, rapid detection, portable equipment, and unrestricted application conditions. In recent years, the development of paper-based microfluidic technology and its integration with various new technologies and methods have promoted the substantial development of POCT technology and methods. The classification and characteristic of the paper are summarized in this review. Paper-based microfluidic sample pretreatment methods, the flow control in the process of reaction and the signal detecting and analyzing methods for the testing results are introduced. The research progress of various kinds of microfluidic paper-based analytical devices (μPADs) toward POCT in recent years is reviewed. Finally, remaining problems and the future prospects in POCT application of paper-based microfluidics are discussed.
- Published
- 2020
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4. [Effects of three sequential occlusal adjustment methods by articulating papers on the characteristics of implant delayed occlusion for single molar].
- Author
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Liang YT, Xie P, Li Q, Qin MT, Li YL, and Deng M
- Subjects
- Bite Force, Molar surgery, Dental Occlusion, Occlusal Adjustment, Tooth
- Abstract
Purpose: To compare the effects of three occlusal adjustment methods in different sequences by articulating paper on the delayed occlusal characteristics of single molars., Methods: Thirty-two implants of first molars were divided into group A(n=12), group B (n=12) and group C (n=12) by sequential adjustment according to random number means, and (100+40), (100+50+30) and (100+40+20) μm sequence occlusal papers were used for occlusal adjustment, respectively. TeeTester was used to measure the delay time and force ratio between prosthesis and adjacent teeth at restoration day, 3 and 6 months after restoration, and to record the number of cases readjusting in each group during follow-up. SPSS 25.0 software package was used for data analysis., Results: There were significant differences in delay time between groups at restoration day (P<0.05), and 3 and 6 months after restoration, delay time of group C was still smaller than that of group A and B (P<0.05). During follow-up, the time of each group showed a trend of shortening (P<0.05), but there was still delayed occlusion. Compared with group B and C, the force ratio in group A was lower at each time(P<0.05). The ratio of each group showed an increasing trend during follow-up (P<0.05), and group C showed the largest increase (P<0.001). The number of cases readjusting was relatively small in group A, and the most was in group C(P<0.05). There was positive correlation between delay time and force difference of prosthesis and adjacent teeth(P<0.001)., Conclusions: The (100+40) μm sequence group had higher occlusal stability and better clinical applicability. The smaller the occlusal contact space realized by the sequential method, the greater the change might be, which requires close follow-up in clinical practice.
- Published
- 2023
5. [The Top 100 papers in the Journal of Allergy and Clinical Immunology of 90th anniversary].
- Author
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Wu QW, Yuan LX, Zheng R, Wang XY, Qiu HJ, Zhang YN, Huang XK, and Yang QT
- Subjects
- Humans, Anniversaries and Special Events, Hypersensitivity
- Published
- 2023
- Full Text
- View/download PDF
6. [Detection of IgG protein in human urine based on vertical flow paper microfluidic chip].
- Author
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Li X, Wang X, Wei Z, Zhang P, Xu J, Xu L, Zheng F, Yang Z, Chen Y, Qiu X, and Zhang L
- Subjects
- Humans, Immunoglobulin G, Kidney, Microfluidics, Microfluidic Analytical Techniques
- Abstract
The kidney is the body's most important organ and the protein components in urine could be detected for diagnosing certain diseases. The amount of IgG protein in urine could be used to determine the degree of kidney function damage. IgG protein in human urine was detected by vertical flow paper-based microfluidic chip, double-antibody sandwich immunoreaction, and cell phone image processing. The results showed that using an IgG antibody concentration of 500 μg/mL and a gold standard antibody concentration of 100 μg/mL, the image signal showed a good linear relationship in the range of IgG concentration of 0.2-3.2 μg/mL, with R
2 =0.973 3 achieved. A complete set of detection devices were designed and the detection method showed good non-specificity.- Published
- 2023
- Full Text
- View/download PDF
7. [Analysis of the characteristics of retracted scientific papers in the field of global liver diseases published by Chinese scholars].
- Author
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Zhong QY, Zhang XY, Luo HH, Jiang X, Zeng XY, Jiang J, Xia HF, Peng Y, Lyu MH, and Tang XW
- Subjects
- Humans, China, Biomedical Research, Liver Diseases, Scientific Misconduct
- Abstract
Objective: To analyze the characteristics of scientific papers in the field of global liver diseases published by Chinese scholars that were retracted for diverse reasons from the Retraction Watch database, so as to provide a reference to publishing-related papers. Methods: The Retraction Watch database was retrieved for retracted papers in the field of global liver disease published by Chinese scholars from March 1, 2008 to January 28, 2021. The regional distribution, source journals, reasons for retraction, publication and retraction times, and others were analyzed. Results: A total of 101 retracted papers that were distributed across 21 provinces/cities were retrieved. Zhejiang area ( n = 17) had the most retracted papers, followed by Shanghai ( n = 14), and Beijing ( n = 11). The vast majority were research papers ( n = 95). The journal PLoS One had the highest number of retracted papers. In terms of time distribution, 2019 ( n = 36) had the most retracted papers. 23 papers, accounting for 8.3% of all retractions, were retracted owing to journal or publisher concerns. Liver cancer (34%), liver transplantation (16%), hepatitis (14%), and others were the main areas of retracted papers. Conclusion: Chinese scholars have a large number of retracted articles in the field of global liver diseases. A journal or publisher chooses to retract a manuscript after investigating and discovering more flawed problems, which, however, require further support, revision, and supervision from the editorial and academic circles.
- Published
- 2023
- Full Text
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8. [Influence of paper mixing pads thickness on the compressive strength of glass ionomer cement].
- Author
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Zhou QM, Ding RY, Li L, Bai W, and Hu JY
- Subjects
- Compressive Strength, Materials Testing, Glass Ionomer Cements, Silicon Dioxide
- Abstract
Objective: To explore the influence of the thickness of mixed cardboard on the compressive strength of glass ionomer cement and the associated factors., Methods: Three different types of glass ionomer cements were mixed on the top of 60, 40, 20 and 1 pieces of paper (P60, P40, P20 and P1), respectively. The compressive strength of the materials was tested after solidification, and the bubble rate was calculated with the assistance of scanning electron microscope., Results: (1) Compressive strength: ① ChemFil Superior glass ionomer (CF): The average compressive strength of P1 group was the highest, which was significantly different from that of P40 and P60 groups ( P values were 0.041 and 0.032 respectively); ② To Fuji IX GP glass ionomer (IX): The average compressive strength of P1 group was the highest, which was statistically different from that of P40 and P60 groups ( P values were 0.042 and 0.038 respectively); ③ Glaslonomer FX-Ⅱ glass ionomer cement (FX): The average compressive strength of P1 group was the highest, which was statistically different from that of P20, P40 and P60 groups ( P values were 0.031, 0.040 and 0.041 respectively), but there was no statistical difference among the other groups. All the three materials showed that the compressive strength of glass ions gradually increased with the decrease of the thickness of the blended paperboard, and the two materials had a highly linear negative correlation, the correlation coefficients of which were CF-0.927, IX-0.989, FX-0.892, respectively. (2) Scanning electron microscope: P1 group had the least bubbles among the three materials., Conclusion: It indicates that the thickness of mixed cardboard has a negative correlation with the compressive strength of glass ions. The thicker the mixed cardboard is, the greater the elasticity is. Excessive elasticity will accelerate the mixing speed when the grinding glass ions. Studies have shown that the faster the speed of artificial mixing is, the more bubbles is produced.The thicker ther mixed cardboard is, the more bubblesn are generated by glass ionomer cement, and the higher the compressive strength is. Using one piece of paper board to mix glass ionomer cement has the least bubbles and can obtain higher compressive strength.
- Published
- 2023
9. [Blue paper of China sudden cardiac death prevention and rescue system construction (2022)].
- Author
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Professional Committee Of Cardiopulmonary Resuscitation Chinese Research Hospital Society, Professional Committee Of Cardiopulmonary Resuscitation Chinese Aging Well Association, Health Culture Committee Chinese Health Association, and Expert Committee Of China Sudden Cardiac Death Prevention And Rescue System Construction
- Subjects
- Humans, China, Death, Sudden, Cardiac prevention & control, Cardiopulmonary Resuscitation
- Abstract
In order to improve the comprehensive ability of China sudden cardiac death prevention and rescue, the Expert Committee of China Sudden Cardiac Death Prevention and Rescue System Construction organized 100 experts and scholars in the field of cardiopulmonary resuscitation to form Blue paper of China sudden cardiac death prevention and rescue system construction (2022). It mainly includes three parts: the organizational structure of the sudden cardiac death prevention and rescue system, the main functions of the sudden cardiac death prevention and rescue system, and the key projects of the sudden cardiac death prevention and rescue system. It is hoped that the China sudden cardiac death prevention and rescue system will be established to serve the life and health of the people wholeheartedly.
- Published
- 2022
- Full Text
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10. [Understanding the behavioural and social drivers of vaccine uptake: introduction and implications of World Health Organization Position Paper, 2022].
- Author
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Jiang BS and Feng LZ
- Subjects
- Humans, Immunization Schedule, Health Policy, World Health Organization, Vaccination, Immunization Programs, Vaccines
- Abstract
On May 20, 2022, World Health Organization (WHO) Position Paper on Understanding the Behavioural and Social Drivers of Vaccine Uptake (BeSD) was published. This review introduced the BeSD toolkit, interventions to increase vaccine uptake, and offered WHO's position and recommendation. Based on immunization practice, this position paper had some implications for improving the vaccination coverage in China: (1) To promote the BeSD toolkit localization; (2) To integrate the measurement and monitoring of BeSD into multisectoral routine efforts; (3) To enhance the diversity and professionalization of immunization practitioners; (4) To design and carry out implementation research scientifically.
- Published
- 2022
- Full Text
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11. [Significance of bacteria detection with filter paper method on diagnosis of diabetic foot wound infection].
- Author
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Zou XH, Zhu YP, Ren GQ, Li GC, Zhang J, Zou LJ, Feng ZB, and Li BH
- Subjects
- Acinetobacter baumannii isolation & purification, Bacteria classification, Diabetic Foot diagnosis, Humans, Predictive Value of Tests, Pseudomonas aeruginosa isolation & purification, Sensitivity and Specificity, Staphylococcal Infections, Staphylococcus aureus isolation & purification, Bacteria isolation & purification, Diabetes Complications microbiology, Diabetic Foot microbiology, Paper, Wound Infection microbiology
- Abstract
Objective: To evaluate the significance of bacteria detection with filter paper method on diagnosis of diabetic foot wound infection. Methods: Eighteen patients with diabetic foot ulcer conforming to the study criteria were hospitalized in Liyuan Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology from July 2014 to July 2015. Diabetic foot ulcer wounds were classified according to the University of Texas diabetic foot classification (hereinafter referred to as Texas grade) system, and general condition of patients with wounds in different Texas grade was compared. Exudate and tissue of wounds were obtained, and filter paper method and biopsy method were adopted to detect the bacteria of wounds of patients respectively. Filter paper method was regarded as the evaluation method, and biopsy method was regarded as the control method. The relevance, difference, and consistency of the detection results of two methods were tested. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of filter paper method in bacteria detection were calculated. Receiver operating characteristic (ROC) curve was drawn based on the specificity and sensitivity of filter paper method in bacteria detection of 18 patients to predict the detection effect of the method. Data were processed with one-way analysis of variance and Fisher's exact test. In patients tested positive for bacteria by biopsy method, the correlation between bacteria number detected by biopsy method and that by filter paper method was analyzed with Pearson correlation analysis. Results: (1) There were no statistically significant differences among patients with wounds in Texas grade 1, 2, and 3 in age, duration of diabetes, duration of wound, wound area, ankle brachial index, glycosylated hemoglobin, fasting blood sugar, blood platelet count, erythrocyte sedimentation rate, C-reactive protein, aspartate aminotransferase, serum creatinine, and urea nitrogen (with F values from 0.029 to 2.916, P values above 0.05), while there were statistically significant differences among patients with wounds in Texas grade 1, 2, and 3 in white blood cell count and alanine aminotransferase (with F values 4.688 and 6.833 respectively, P <0.05 or P <0.01). (2) According to the results of biopsy method, 6 patients were tested negative for bacteria, and 12 patients were tested positive for bacteria, among which 10 patients were with bacterial number above 1×10(5)/g, and 2 patients with bacterial number below 1×10(5)/g. According to the results of filter paper method, 8 patients were tested negative for bacteria, and 10 patients were tested positive for bacteria, among which 7 patients were with bacterial number above 1×10(5)/g, and 3 patients with bacterial number below 1×10(5)/g. There were 7 patients tested positive for bacteria both by biopsy method and filter paper method, 8 patients tested negative for bacteria both by biopsy method and filter paper method, and 3 patients tested positive for bacteria by biopsy method but negative by filter paper method. Patients tested negative for bacteria by biopsy method did not tested positive for bacteria by filter paper method. There was directional association between the detection results of two methods ( P =0.004), i. e. if result of biopsy method was positive, result of filter paper method could also be positive. There was no obvious difference in the detection results of two methods ( P =0.250). The consistency between the detection results of two methods was ordinary (Kappa=0.68, P =0.002). (3) The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of filter paper method in bacteria detection were 70%, 100%, 1.00, 0.73, and 83.3%, respectively. Total area under ROC curve of bacteria detection by filter paper method in 18 patients was 0.919 (with 95% confidence interval 0-1.000, P =0.030). (4) There were 13 strains of bacteria detected by biopsy method, with 5 strains of Acinetobacter baumannii, 5 strains of Staphylococcus aureus, 1 strain of Pseudomonas aeruginosa, 1 strain of Streptococcus bovis, and 1 strain of bird Enterococcus . There were 11 strains of bacteria detected by filter paper method, with 5 strains of Acinetobacter baumannii, 3 strains of Staphylococcus aureus, 1 strain of Pseudomonas aeruginosa, 1 strain of Streptococcus bovis, and 1 strain of bird Enterococcus . Except for Staphylococcus aureus, the sensitivity and specificity of filter paper method in the detection of the other 4 bacteria were all 100%. The consistency between filter paper method and biopsy method in detecting Acinetobacter baumannii was good (Kappa=1.00, P <0.01), while that in detecting Staphylococcus aureus was ordinary (Kappa=0.68, P <0.05). (5) There was no obvious correlation between the bacteria number of wounds detected by filter paper method and that by biopsy method ( r =0.257, P =0.419). There was obvious correlation between the bacteria numbers detected by two methods in wounds with Texas grade 1 and 2 (with r values as 0.999, P values as 0.001). There was no obvious correlation between the bacteria numbers detected by two methods in wounds with Texas grade 3 ( r =-0.053, P =0.947). Conclusions: The detection result of filter paper method is in accordance with that of biopsy method in the determination of bacterial infection, and it is of great importance in the diagnosis of local infection of diabetic foot wound.
- Published
- 2017
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12. [Introduction and implications of WHO position paper: vaccines against influenza, May 2022].
- Author
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Feng LZ, Jiang HY, Yi J, Qian LL, Xu JD, Zheng LB, Ma ZB, Peng SJ, Jiang ST, Xu EF, Chen LH, Wang LD, Gao WZ, and Yang W
- Subjects
- Humans, SARS-CoV-2, World Health Organization, COVID-19, Influenza Vaccines, Influenza, Human epidemiology, Influenza, Human prevention & control
- Abstract
On May 13, 2022, World Health Organization(WHO) Position Paper on Influenza Vaccine (2022 edition) was published. This position paper updates information on influenza epidemiology, high risk population, the impact of immunization on disease, influenza vaccines and effectiveness and safety, and propose WHO's position and recommendation that all countries should consider implementing seasonal influenza vaccine immunization programmes to prepare for an influenza pandemic. In addition, it proposes that the influenza surveillance platform can be integrated with the surveillance of other respiratory viruses, such as SARS-CoV-2 and Respiratory Syncytial Virus. This position paper has some implications for the prevention and control of influenza and other respiratory infectious diseases in China: (1) Optimize influenza vaccine policies to facilitate the implementation of immunization services; (2) Influenza prevention and control should from the perspective of Population Medicine focus on the individual and community to integrate with "Promotion, Prevention, Diagnosis, Control, Treatment, Rehabilitation"; (3) Incorporate prevention and control of other respiratory infectious diseases such as influenza, COVID-19, respiratory syncytial virus and adenovirus, and intelligently monitor by integrating multi-channel data to achieve the goal of co-prevention and control of multiple diseases.
- Published
- 2022
- Full Text
- View/download PDF
13. [Diagnostic value of a novel test paper detection of ECP in nasal secretion for allergic rhinitis].
- Author
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Li H, Xi Y, Chen J, Chen J, Deng Y, and Tao Z
- Subjects
- Case-Control Studies, Cytokines blood, Humans, Sensitivity and Specificity, Eosinophil Cationic Protein analysis, Reagent Strips, Rhinitis, Allergic blood, Rhinitis, Allergic diagnosis
- Abstract
Objective: To explore the diagnostic value of a novel test paper, which detect eosinophil cationic protein(ECP) of nasal secretion in allergic rhinitis(AR). Methods: Nasal secretion and serum samples from 107 patients with allergic rhinitis(AR group) and 40 healthy volunteers(control group) were selected. The nasal symptoms were also evaluated in AR group. The degree of ECP coloration was evaluated by nasal secretion eosinophil cationic protein-myeloperoxid(ECP-MPO) test paper, and the concentration of ECP in nasal secretion and the concentration of cytokines in serum were detected at the same time. The difference and correlation among these indexes were analyzed. The best cutoff value and test efficiency of ECP chromogenic grade and concentration of nasal secretion were calculated by receiver operating characteristic curve(ROC). Results: The concentration of ECP in nasal secretion of AR patients was significantly higher than that of healthy controls( P <0.05). The color grade of nasal secretion detected by the test paper was positively correlated with the concentration of ECP in nasal secretion( P <0.05), and there was significant difference among different grades( P <0.05). There was a satisfying symmetry between the ECP color grade of nasal secretion and the serum specific IgE(sIgE) level as well as a high diagnostic consistency between them( P <0.05). The area under the curve(AUC) of ECP concentration ROC in nasal secretion was 0.807 2, corresponding to 64% sensitivity and 85% specificity when the cutoff value was set at 0.980 5; when the cutoff value was set at 1, the AUC of nasal secretion ECP color grading was 0.941 9, corresponding to 92% sensitivity and 94% specificity. No clear correlation between the concentration of ECP in nasal secretion and serum cytokines was found( P >0.05). Conclusion: The results of this novel test paper is in good agreement with those of serological allergens. It could serve as a preliminary test to evaluate the severity of allergy with satisfactory sensitivity and specificity, and is especially suitable in clinical practice for primary hospital., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
- Published
- 2022
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14. [Characterization of Humicola insolens cutinase-tachystatin A2 fusion protein and its application in treatment of recycled paper stickies].
- Author
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Li G, Liu Z, Zhang Y, and Wu J
- Subjects
- Polyurethanes, Carboxylic Ester Hydrolases genetics, Fungal Genus Humicola
- Abstract
With the decrease of forest timber resources, the recycling of waste paper has received increasing attention. However, the stickies produced in the process of waste paper recycling may negatively affect the production of recycled paper. The biological decomposition of stickies, which has the advantages of high efficiency, high specificity and pollution-free, is achieved mainly through the enzymatic cleavage of the ester bond in the stickies components to prevent flocculation. Cutinase is a serine esterase that can degrade some components of the stickies. Previous research indicated that the anchor peptide tachystatin A2 (TA2) is able to bind polyurethane. In this study, the cutinase HiC derived from Humicola insolens was used to construct a fusion protein HiC-TA2 by megaprimer PCR of the whole plasmid (MEGAWHOP). The enzymatic properties and the degradation efficiency of the fusion protein on poly(ethyl acrylate) (PEA), a model substrate of stickies component, were determined. The results showed that the degradation efficiency, the size decrease of PEA particle, and the amount of ethanol produced by HiC-TA2 were 1.5 times, 6.8 times, and 1.4 times of that by HiC, respectively. These results demonstrated that TA2 improved the degradation efficiency of HiC on PEA. This study provides a useful reference for biological decomposition of stickies produced in the process of recycled paper production.
- Published
- 2022
- Full Text
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15. [Evolution of Material Metabolism in China's Pulp and Paper Industry].
- Author
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Liu X, Yang T, Wu HJ, and Yuan ZW
- Subjects
- China, Industry, Recycling
- Abstract
The pulp and paper industry is an important industry that is closely related to national socioeconomic development. To understand the historical trends of resource consumption and environmental pollution, we conducted an economy-wide material flow analysis and quantitatively evaluated the dynamic characteristics of input-output balances, material metabolism intensity, and resource recycling rate of China's pulp and paper industry, from 2005 to 2017. The results indicate downward trends in the material inputs and outputs of China's pulp and paper industry from 2005 to 2017, with water contributing over 90% of the totals. In recent years, with the continuous optimization of the raw material structure of the paper industry, the proportion of non-wood pulping has dropped from 42% to 13% and has been replaced by mainly waste paper pulping and wood pulping. Resource consumption can still be greatly reduced. In 2017, the amount of direct material input per ton of paper and paperboard had decreased by 67% from 2005 to 26 t. The consumption of fresh water per ton of paper and paperboard dropped by approximately 69% over the study period, whereas the water recycling rate increased significantly, reaching 77% in 2017. At present, the production of paper and paperboard is increasingly dependent on the input of domestic waste paper and imported wood, the proportions of which have increased from 21% and 9% in 2005 to 60% and 31% in 2017, respectively. However, the rate of domestic waste paper recycling is relatively low, and measures such as strengthening the construction of the recycling system and educating the residents about recycling are needed to alleviate the shortage of raw materials caused by restrictions on waste paper imports.
- Published
- 2021
- Full Text
- View/download PDF
16. [Applications of microfluidic paper-based chips in environmental analysis and detection].
- Author
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Zhang Y, Qi J, Liu F, Wang N, Sun X, Cui R, Yu J, Ye J, Liu P, Li B, and Chen L
- Abstract
Microfluidic paper-based chips have many advantages such as ease of integration, miniaturization, and automation; high throughput; low production cost; easy portability; easy storage and transportation, environmental friendliness, and feasibility of instantaneous detection. These chips are widely used in clinical diagnosis, food quality control, and immunoassays. With the continuous development of microfluidic paper microarrays in recent years, they have also received great attention for environmental contaminant analysis and detection, and research in this field has been intensive, showing excellent prospects for application. This review summarizes the latest research progress in environmental analysis from the perspective of the application of microfluidic paper-based chips, as well as future development trends and challenges. More than 150 papers from the Science Citation Index (SCI) and Chinese core journals are cited in this paper. This review includes the advantages of microfluidic paper-based chips for environmental analysis and detection; the introduction of paper chip fabrication methods, including wax printing, photolithography, dicing, plasma, laser, and inkjet etching; and the introduction of advanced analytical methods based on paper chips, such as electrochemical analysis, fluorescence analysis, colorimetric analysis, surface-enhanced Raman analysis, and integrated sensing methods. The future development trends and prospects of environmental analysis based on microfluidic paper-based chips are also reviewed. Through a rich and comprehensive review of recent related research, it is shown that although microfluidic paper-based chip technology has only been developed for little more than a decade since its introduction, this technology has seen rapid development in environmental analysis-related research and has yielded rich results. The hydrophilic and porous nature of cellulose in paper as a chip substrate allows the passive transport of liquids without an external power source. The diversity of available microfluidic paper-based chip fabrication and analysis methods allows flexible selection and matching according to different environmental conditions and detection requirements, so that the best detection results can be obtained. Moreover, microfluidic paper chips as detection platforms show good biocompatibility in the analysis and detection of environmental pollutants, enabling the analysis of more types of pollutants. The used paper is biodegradable and can be directly disposed of as ordinary garbage after appropriate degradation treatment; thus it is environmentally friendly and does not impact the health of the operators. In addition, the low production cost and simple operation of the paper chip design study make it possible to fabricate low-cost, portable, and practical analytical equipment, which is important for rapid testing of the conventional environment. However, there are some inherent disadvantages: the mechanical strength of the paper is not sufficiently high to resist deformation; degree of fluid control is difficult to achieve the desired effect, and the sample flow may be lost due to leakage; multiple contaminants may interfere with one another when analyzed in parallel; there are difficulties in commercial mass production. However, these problems also point to the direction for the research and development of microfluidic paper-based chips in the field of environmental testing. With continuous advances in manufacturing and analysis technologies, microfluidic paper-based chips are expected to play a more prominent role in future environmental analysis.
- Published
- 2021
- Full Text
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17. [How to write a clinical research paper that can be published].
- Author
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Zhao YM and Chu HL
- Subjects
- Writing
- Abstract
A clinical research paper which could be published should be based on a qualified clinical research, which includes a reasonable topic from clinical settings, concentrating resources to answer a question, having new findings and drawing concrete conclusions. The author should prepare a scientific story, which originates from clinical scenarios, with working hypothesis and research design, standardized organization and implementation, reasonable analysis and evaluation. The conclusion should be based on the research results, and go back to the problems and needs to form a closed loop. The key point of writing a clinical research paper is to provide complete information and show a complete research process according to the writing format and specification of the paper. Finally, the key points of the current paper help avoid detours and improve the probability of paper publication.
- Published
- 2021
- Full Text
- View/download PDF
18. [Method for environmental management in paper industry based on pollution control technology simulation].
- Author
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Zhang XY and Wen ZG
- Subjects
- Ammonia analysis, Biological Oxygen Demand Analysis, China, Models, Theoretical, Wastewater analysis, Industry, Paper, Water Pollution prevention & control
- Abstract
To evaluate the reduction potential of industrial water pollutant emissions and to study the application of technology simulation in pollutant control and environment management, an Industrial Reduction Potential Analysis and Environment Management (IRPAEM) model was developed based on coupling of "material-process-technology-product". The model integrated bottom-up modeling and scenario analysis method, and was applied to China's paper industry. Results showed that under CM scenario, the reduction potentials of waster water, COD and ammonia nitrogen would reach 7 x 10(8) t, 39 x 10(4) t and 0.3 x 10(4) t, respectively in 2015, 13.8 x 10(8) t, 56 x 10(4) t and 0.5 x 10(4) t, respectively in 2020. Strengthening the end-treatment would still be the key method to reduce emissions during 2010-2020, while the reduction effect of structure adjustment would be more obvious during 2015-2020. Pollution production could basically reach the domestic or international advanced level of clean production in 2015 and 2020; the index of wastewater and ammonia nitrogen would basically meet the emission standards in 2015 and 2020 while COD would not.
- Published
- 2014
19. [Concentrations, distribution characteristics and electron beam radiolysis degradation of PCDD/Fs in waste water from a paper mill].
- Author
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Qing X, Huang JQ, Yu XW, Zhang SK, Yang YY, Ren MZ, and Wen YL
- Subjects
- Electrons, Industry, Polychlorinated Dibenzodioxins analysis, Benzofurans analysis, Paper, Polychlorinated Dibenzodioxins analogs & derivatives, Polymers analysis, Wastewater chemistry, Water Purification methods
- Abstract
Concentrations and distribution characteristics of 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and dibenzofurans (2,3,7,8-PCDD/Fs) were analyzed in waste water from a paper mill. And concentrations of 2,3,7,8-PCDD/Fs in waste water before and after electron beam irradiation with different doses were compared. The feasibility, mechanism and rates of 2,3,7,8-PCDD/Fs degradation were discussed. The PCDD/Fs concentrations and corresponding I-TEQ (toxic equivalent quantity) values were 239 pg x L(-1) and 41.0 pg x L(-1), respectively, in the waste water. The concentrations of total 2,3,7,8-PCDD/Fs decreased after electron beam radiolysis at a dose of 30 kGy and 60 kGy with degradation rates of 5.27% and 23.6%, respectively.
- Published
- 2014
20. [Levels and Risk Assessment of Short and Medium-Chain Chlorinated Paraffins in Soil from Paper Mill Area].
- Author
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Zhang PX, Gao LR, Song SJ, Qiao L, Xu C, Huang D, Wang S, Jiang SJ, and Zheng MH
- Subjects
- Child, China, Environmental Monitoring, Humans, Risk Assessment, Soil, Hydrocarbons, Chlorinated analysis, Paraffin analysis
- Abstract
Short-chain chlorinated paraffins are persistent organic pollutants, and chlorinated paraffins were widely used as sizing agent in the paper industry. In order to investigate the levels and risk assessment of short-chain and medium-chain chlorinated paraffins in the paper mill plant, the surface soil and soil of different depths were collected.The concentrations, congener group profiles of short-chain chlorinated paraffins (SCCPs) and medium-chain chlorinated paraffins (MCCPs) in soil were determined by two-dimensional gas chromatography coupled with electron capture-negative ion mass spectrometry. The SCCPs and MCCPs concentrations were 42-3853 ng·g
-1 and 34-2091 ng·g-1 . The chlorine contents were 59.9%-61.9% and 48.7%-52.8%. The concentrations of SCCPs and MCCPs were different in the soil collected in different sampling site. The concentration of SCCPs and MCCPs were relatively higher in soil of sewage treatment area and coating area. The CP levels in soil from the paper mill plant were at a high level compared with those in other regions. C10 Cl6-7 and C14-15 Cl5 were the main congener groups in most soil samples. The results of principal component analysis showed that the CP52 commercial products may be sources of SCCPs and MCCPs in the soil. The risk quotient (RQ) for SCCPs and MCCPs were assessed in soil of paper mill plant. The results showed that the RQ values for SCCPs in soil ranged from 0.01 to 0.73 which are the medium risk, and the RQ values for MCCPs in soil ranged from 0 to 0.07, which are the low risk. The human exposure values of children and adults are lower than TDI[10 μg·(kg·d)-1 ] in both cases. The health risks caused by non-dietary exposure under paper mill area are low.- Published
- 2021
- Full Text
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