In order to deepen the research on the coordination mechanism of ecological protection and economic development of the urban agglomerations in the Yellow River Basin, and to provide references for the research on high-quality development in the Yellow River Basin, taking the Lanzhou-Xi' an urban agglomeration, the Guanzhong Plain urban agglomeration, the Shandong Peninsula urban agglomeration, and the Huhhot-Baotou-Erdos-Yulin urban agglomeration, Central China urban agglomeration, Central Shanxi urban agglomeration, and Ningxia urban agglomeration along the Yellow River as the research objects, this paper established an index system according to the four subsystems of ecological environment, economic development, human water relationship, and people' s happiness . It adopted the entropy weight method and the coefficient of variation method to determine the index weights and SMI-P model to calculate the coordination degree between ecologic; J protection and high-quality development, and analyzed the changes in the coordination degree between ecological protection and high-quality development in urban agglomerations along the Yellow River from 2009 to 2018. The results show that the coordination degree of ecological protection and high-quality development of the urban agglomerations along the Yellow River presents a cascade distribution pattern of high in the cast and low in the west (high in the downstream and low in the upper reaches) ; the degree of coordination between protection and high-quality development is rising, and the difference in the degree of coordination among urban agglomerations is gradually decreasing; in 2009, only the Shandong Peninsula urban agglomeration is in a state of 'close to synergy", while most other urban agglomerations arc in a state of "on the verge of imbalance" ; in 2018, the Central China urban agglomeration and the Huhhot-Baotou-Erdos -Yulin urban agglomeration also reach a state of "close to synergy", while other urban agglomerations are about to reach a state of "close to synergy" ; there arc: significant spatial differences of the coordinated development index among four subsystems (i.e. ecological environment, economic development, human-water relationship, and people' s happiness of each urban agglomeration) . The urban agglomeration with high degree of coordination has a weaker subsystem coordinated development index, while the urban agglomeration with a low degree of coordination has a larger subsystem coordinated development index. Therefore, each urban agglomeration should he adequate to give full play to their respective location advantages and resource advantages, strengthen their weaknesses, and implement differentiated ecological protection and high-quality economic coordinated development. [ABSTRACT FROM AUTHOR]