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4. ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Author

Elitzur, Sarah, Shiloh, Ruth, Loeffen, Jan L. C., Pastorczak, Agata, Takagi, Masatoshi, Bomken, Simon, Baruchel, Andre, Lehrnbecher, Thomas, Tasian, Sarah K., Abla, Oussama, Arad-Cohen, Nira, Astigarraga, Itziar, Ben-Harosh, Miriam, Bodmer, Nicole, Brozou, Triantafyllia, Ceppi, Francesco, Chugaeva, Liliia, Dalla Pozza, Luciano, Ducassou, Stephane, Escherich, Gabriele, Farah, Roula, Gibson, Amber, Hasle, Henrik, Hoveyan, Julieta, Jacoby, Elad, Jazbec, Janez, Junk, Stefanie, Kolenova, Alexandra, Lazic, Jelena, Lo Nigro, Luca, Mahlaoui, Nizar, Miller, Lane, Papadakis, Vassilios, Pecheux, Lucie, Pillon, Marta, Sarouk, Ifat, Stary, Jan, Stiakaki, Eftichia, Strullu, Marion, Tran, Thai Hoa, Ussowicz, Marek, Verdu-Amoros, Jaime, Wakulinska, Anna, Zawitkowska, Joanna, Stoppa-Lyonnet, Dominique, Taylor, A. Malcolm, Shiloh, Yosef, Izraeli, Shai, Minard-Colin, Veronique, Schmiegelow, Kjeld, Nirel, Ronit, Attarbaschi, Andishe, and Borkhardt, Arndt

Published
2024
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8. Effect of rituximab on immune status in children with mature B-cell non-Hodgkin lymphoma: a prespecified secondary analysis of the Inter-B-NHL Ritux 2010 trial

Author

Alexander, Sarah, Aupérin, Anne, Bomken, Simon, Csóka, Monika, Kazanowska, Bernarda, Chiang, Alan K, Andres, Mara, Uyttebroeck, Anne, Burke, G A Amos, Zsiros, József, Pillon, Marta, Bollard, Catherine M, Mussolin, Lara, Verdu-Amoros, Jaime, Neven, Bénédicte, Barkauskas, Donald A, Wheatley, Keith, Patte, Catherine, Gross, Thomas G, and Minard-Colin, Véronique

Published
2023
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9. Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma

Author

Beishuizen, Auke, Mellgren, Karin, Andrés, Mara, Auperin, Anne, Bacon, Chris M, Bomken, Simon, Burke, G A Amos, Burkhardt, Birgit, Brugieres, Laurence, Chiang, Alan K S, Damm-Welk, Christine, d'Amore, Emanuele, Horibe, Keizo, Kabickova, Edita, Khanam, Tasneem, Kontny, Udo, Klapper, Wolfram, Lamant, Laurence, Le Deley, Marie-Cecile, Loeffen, Jan, Macintyre, Elizabeth, Mann, Georg, Meyer-Wentrup, Friederike, Michgehl, Ulf, Minard-Colin, Veronique, Mussolin, Lara, Oschlies, Ilske, Patte, Catherine, Pillon, Marta, Reiter, Alfred, Rigaud, Charlotte, Ronceray, Leila, Salaverria, Itziar, Simonitsch-Klupp, Ingrid, Uyttebroeck, Anne, Verdu-Amoros, Jaime, Williams, Denise, Woessmann, Wilhelm, Wotherspoon, Andrew, Wrobel, Grazyna, Zimmermann, Martin, Attarbaschi, Andishe, and Turner, Suzanne D

Published
2023
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10. Oncological pediatric early warning score: a dedicated tool to predict patient's clinical deterioration and need for pediatric intensive care treatment.

Author

Maccarana, Teresa, Pillon, Marta, Bertozzi, Veronica, Carraro, Elisa, Cavallaro, Elena, Bonardi, Claudia Maria, Marchetto, Luca, Reggiani, Giulia, Tondo, Annalisa, Rosa, Camilla, Comoretto, Rosanna Irene, Amigoni, Angela, and Biffi, Alessandra

Subjects
*EARLY warning score, *MEDICAL record databases, *PEDIATRIC intensive care, *CLINICAL deterioration, *MEDIAN (Mathematics)
Abstract

Pediatric oncohematological patients frequently require PICU admission during their clinical history. The O-PEWS is a specific score developed to predict the need for PICU admission of oncohematological children. This study aimed at i) describing the trend of the O-PEWS in a cohort of patients hospitalized in the Pediatric Oncohematology ward and transferred to the PICU of Padua University Hospital, measured at different time-points in the 24 hours before PICU admission and to evaluate its association with mortality and presence of organ failure; ii) investigating the association between the recorded O-PEWS, and PIM3, number of organ failure and the need for ventilation, dialysis and inotropes. This retrospective single-center study enrolled oncohematological children admitted to the PICU between 2017 and 2021. The O-PEWS, ranging between 0 and 15, was calculated on the available medical records and the TIPNet-Network database at 24 (T-24), 12 (T-12), 6 (T-6) and 0 (T0) hours before PICU admission. RESULTS: 101 PICU admissions, related to 80 children, were registered. During the 24 hours prior to PICU admission, the O-PEWS progressively increased in all the patients. At T-24 the median O-PEWS was 3 (IQR 1-5), increasing to a median value of 6 (IQR 4-8) at T0. The O-PEWS was positively associated with mortality, organ failure and the need for ventilation at all the analyzed time-points and with the need for dialysis at T-6. The O-PEWS appears as a useful tool for predicting early clinical deterioration in oncohematological patients and for anticipating the initiation of life-support treatments. [ABSTRACT FROM AUTHOR]

Published
2024
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12. ATMgerm line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Author

Elitzur, Sarah, Shiloh, Ruth, Loeffen, Jan L. C., Pastorczak, Agata, Takagi, Masatoshi, Bomken, Simon, Baruchel, Andre, Lehrnbecher, Thomas, Tasian, Sarah K., Abla, Oussama, Arad-Cohen, Nira, Astigarraga, Itziar, Ben-Harosh, Miriam, Bodmer, Nicole, Brozou, Triantafyllia, Ceppi, Francesco, Chugaeva, Liliia, Dalla Pozza, Luciano, Ducassou, Stephane, Escherich, Gabriele, Farah, Roula, Gibson, Amber, Hasle, Henrik, Hoveyan, Julieta, Jacoby, Elad, Jazbec, Janez, Junk, Stefanie, Kolenova, Alexandra, Lazic, Jelena, Lo Nigro, Luca, Mahlaoui, Nizar, Miller, Lane, Papadakis, Vassilios, Pecheux, Lucie, Pillon, Marta, Sarouk, Ifat, Stary, Jan, Stiakaki, Eftichia, Strullu, Marion, Tran, Thai Hoa, Ussowicz, Marek, Verdu-Amoros, Jaime, Wakulinska, Anna, Zawitkowska, Joanna, Stoppa-Lyonnet, Dominique, Taylor, A. Malcolm, Shiloh, Yosef, Izraeli, Shai, Minard-Colin, Veronique, Schmiegelow, Kjeld, Nirel, Ronit, Attarbaschi, Andishe, and Borkhardt, Arndt

Abstract

•The major cause of death in patients with ataxia-telangiectasia and hematological malignancies is treatment-related toxicity.•The germ line ATMpathogenic variant functional class is a robust outcome predictor, which can be applied to therapy stratification.

Published
2024
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14. Late-onset and long-lasting autoimmune neutropenia: an analysis from the Italian Neutropenia Registry

Author

Fioredda, Francesca, Rotulo, Gioacchino Andrea, Farruggia, Piero, Dagliano, Francesca, Pillon, Marta, Trizzino, Angela, Notarangelo, Lucia, Luti, Laura, Lanza, Tiziana, Terranova, Paola, Lanciotti, Marina, Ceccherini, Isabella, Grossi, Alice, Porretti, Laura, Verzegnassi, Federico, Mastrodicasa, Elena, Barone, Angelica, Russo, Giovanna, Bonanomi, Sonia, Boscarol, Gianluca, Finocchi, Andrea, Veltroni, Marinella, Ramenghi, Ugo, Onofrillo, Daniela, Martire, Baldassare, Ghilardi, Roberta, Giordano, Paola, Ladogana, Saverio, Marra, Nicoletta, Zanardi, Sabrina, Beier, Fabian, Miano, Maurizio, and Dufour, Carlo

Published
2020
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15. Large B-cell lymphoma-IRF4+ in children and young people: time to reduce chemotherapy in a rare malignant mature B-cell neoplasm?

Author

Huibers, Minke Henrina Willemina, primary, Abla, Oussama, additional, Andres, Mara, additional, Balagué, Olga, additional, Beishuizen, Auke, additional, Carraro, Elisa, additional, Chiang, Alan Kwok Shing, additional, Csoka, Monika, additional, David, Bianca-Andreea, additional, de Ville de Goyet, Maelle, additional, Gilad, Gil, additional, Hori, Daiki, additional, Kotecha, Rishi Sury, additional, Kabickova, Edita, additional, Klapper, Wolfram, additional, Miakova, Natalia, additional, Minard-Colin, Véronique, additional, Nakazawa, Atsuko, additional, Pillon, Marta, additional, Rigaud, Charlotte, additional, Salaverria, Itziar, additional, Tölle, Ida, additional, Verdu-Amorós, Jaime, additional, von Mersi, Hannah, additional, Woessmann, Wilhelm, additional, Burkhardt, Birgit, additional, and Attarbaschi, A, additional

Published
2024
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16. Primary central nervous system lymphoma: initial features, outcome, and late effects in 75 children and adolescents

Author

Attarbaschi, Andishe, Abla, Oussama, Ronceray, Leila, Bansil, Shweta, Bomken, Simon, Burkhardt, Birgit, Ceppi, Francecso, Chiang, Alan K.S., Dave, Hema, Fedorova, Alina, Henry, Michael, Jazbec, Janez, Kabickova, Edita, Kotecha, Rishi S., Lazic, Jelena, Loeffen, Jan, Miakova, Natalia, Osumi, Tomoo, Pillon, Marta, Pourtsidis, Apostolos, Rigaud, Charlotte, Tamamyan, Gevorg, Tandon, Sneha, Uyttebroeck, Anne, Verdu-Amoros, Jamie, Woessmann, Wilhelm, Wrobel, Grazyna, and Giulino-Roth, Lisa

Published
2019
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17. Long-term outcome after allogeneic hematopoietic stem cell transplantation for Shwachman–Diamond syndrome: a retrospective analysis and a review of the literature by the Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation (SAAWP-EBMT)

Author

Cesaro, Simone, Pillon, Marta, Sauer, Martin, Smiers, Frans, Faraci, Maura, de Heredia, Cristina Diaz, Wynn, Robert, Greil, Johann, Locatelli, Franco, Veys, Paul, Uyttebroeck, Anne, Ljungman, Per, Chevalier, Patrice, Ansari, Marc, Badell, Isabel, Güngör, Tayfun, Salim, Rahuman, Tischer, Johanna, Tecchio, Cristina, Russell, Nigel, Chybicka, Alicja, Styczynski, Jan, Krivan, Gergely, Smith, Owen, Stein, Jerry, Afanasyev, Boris, Pochon, Cécile, Menconi, Maria Cristina, Bosman, Paul, Mauro, Margherita, Tridello, Gloria, de Latour, Regis Peffault, and Dufour, Carlo

Published
2020
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18. Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes

Author

Pizzi, Marco, primary, Bongiovanni, Lucia, additional, Lorenzi, Luisa, additional, Righi, Simona, additional, Scarmozzino, Federico, additional, Balzarini, Piera, additional, Santoro, Luisa, additional, Mussolin, Lara, additional, Carraro, Elisa, additional, Pillon, Marta, additional, Bonaldi, Laura, additional, Vianello, Fabrizio, additional, Agostinelli, Claudio, additional, Ponzoni, Maurilio, additional, Dei Tos, Angelo Paolo, additional, and Sabattini, Elena, additional

Published
2023
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20. Brentuximab vedotin for paediatric relapsed or refractory Hodgkin's lymphoma and anaplastic large-cell lymphoma: a multicentre, open-label, phase 1/2 study

Author

Locatelli, Franco, Mauz-Koerholz, Christine, Neville, Kathleen, Llort, Anna, Beishuizen, Auke, Daw, Stephen, Pillon, Marta, Aladjidi, Nathalie, Klingebiel, Thomas, Landman-Parker, Judith, Medina-Sanson, Aurora, August, Keith, Sachs, Jessica, Hoffman, Kristen, Kinley, Judith, Song, Sam, Song, Gregory, Zhang, Stephen, Suri, Ajit, and Gore, Lia

Published
2018
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22. Outcomes of Children with Hemophagocytic Lymphohistiocytosis Given Allogeneic Hematopoietic Stem Cell Transplantation in Italy

Author

Messina, Chiara, Zecca, Marco, Fagioli, Franca, Rovelli, Attilio, Giardino, Stefano, Merli, Pietro, Porta, Fulvio, Aricò, Maurizio, Sieni, Elena, Basso, Giuseppe, Ripaldi, Mimmo, Favre, Claudio, Pillon, Marta, Marzollo, Antonio, Rabusin, Marco, Cesaro, Simone, Algeri, Mattia, Caniglia, Maurizio, Di Bartolomeo, Paolo, Ziino, Ottavio, Saglio, Francesco, Prete, Arcangelo, and Locatelli, Franco

Published
2018
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23. Italian Multicenter Study on Accuracy of 18F-FDG PET/CT in Assessing Bone Marrow Involvement in Pediatric Hodgkin Lymphoma

Author

Cistaro, Angelina, Cassalia, Laura, Ferrara, Cinzia, Quartuccio, Natale, Evangelista, Laura, Bianchi, Maurizio, Fagioli, Franca, Bisi, Gianni, Baldari, Sergio, Zanella, Alessandro, Pillon, Marta, Zucchetta, Pietro, Burei, Marta, Sala, Alessandra, Guerra, Luca, Guglielmo, Priscilla, Burnelli, Roberta, Panareo, Stefano, Scalorbi, Federica, Rambaldi, Ilaria, Piccardo, Arnoldo, Garaventa, Alberto, Familiari, Demetrio, Fornito, Maria Concetta, Lopci, Egesta, Mascarin, Maurizio, Altini, Corinna, Ferrari, Cristina, Perillo, Teresa, Santoro, Nicola, Borsatti, Eugenio, and Rubini, Giuseppe

Published
2018
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24. Current practices of follow-up programs for childhood cancer survivors in Italy

Author

Terenziani, Monica, primary, Tozzi, Alberto Eugenio, additional, Diaco, Laura, additional, Biasin, Eleonora, additional, Cattoni, Alessandro, additional, Croci, Ileana, additional, Fraschini, Donatella, additional, Giorgiani, Giovanna, additional, Haupt, Riccardo, additional, Muraca, Monica, additional, Pillon, Marta, additional, Sironi, Giovanna, additional, Valsecchi, Maria Grazia, additional, and Mastronuzzi, Angela, additional

Published
2023
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26. Pearson Syndrome: A Retrospective Cohort Study from the Marrow Failure Study Group of A.I.E.O.P. (Associazione Italiana Emato-Oncologia Pediatrica)

Author

Farruggia, Piero, Di Cataldo, Andrea, Pinto, Rita M., Palmisani, Elena, Macaluso, Alessandra, Valvo, Laura Lo, Cantarini, Maria E., Tornesello, Assunta, Corti, Paola, Fioredda, Francesca, Varotto, Stefania, Martire, Baldo, Moroni, Isabella, Puccio, Giuseppe, Russo, Giovanna, Dufour, Carlo, Pillon, Marta, Baumgartner, Matthias, Series editor, Patterson, Marc, Series editor, Rahman, Shamima, Series editor, Peters, Verena, Series editor, Morava, Eva, Editor-in-chief, and Zschocke, Johannes, Series editor

Published
2016
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29. Quantitative assessment of minimal residual disease for monitoring of paediatric patients with relapsed/refractory anaplastic large‐cell lymphoma treated with brentuximab vedotin: A case series.

Author

Contarini, Giorgia, Carraro, Elisa, Lovisa, Federica, Martire, Gaia, Lo Nigro, Luca, Sala, Alessandra, Pillon, Marta, and Mussolin, Lara

Subjects
ANAPLASTIC large-cell lymphoma, CHILD patients, POSITRON emission tomography computed tomography, PATIENT monitoring, HODGKIN'S disease, ANAPLASTIC thyroid cancer
Abstract

This article discusses the use of brentuximab vedotin (BV) for the treatment of relapsed or refractory anaplastic large-cell lymphoma (ALCL) in pediatric patients. The study focuses on the role of minimal residual disease (MRD) monitoring using droplet digital PCR (dPCR) to assess treatment response and predict relapse. The results suggest that multiple cycles of BV are necessary to achieve complete remission, and MRD positivity may serve as an early indicator of relapse. The study acknowledges its limitations due to its retrospective nature and small sample size. The research was supported by various funding sources and the authors declare no conflicts of interest. [Extracted from the article]

Published
2024
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31. Cost-effectiveness analysis alongside the inter-B-NHL ritux 2010 trial: rituximab in children and adolescents with B cell non-Hodgkin’s lymphoma

Author

Lueza, Béranger, primary, Aupérin, Anne, additional, Rigaud, Charlotte, additional, Gross, Thomas G., additional, Pillon, Marta, additional, Delgado, Rafael F., additional, Uyttebroeck, Anne, additional, Amos Burke, G. A., additional, Zsíros, József, additional, Csóka, Monika, additional, Simonin, Mathieu, additional, Patte, Catherine, additional, Minard-Colin, Véronique, additional, and Bonastre, Julia, additional

Published
2023
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33. Current practices of follow-up programs for childhood cancer survivors in Italy

Author

Terenziani, M, Tozzi, A, Diaco, L, Biasin, E, Cattoni, A, Croci, I, Fraschini, D, Giorgiani, G, Haupt, R, Muraca, M, Pillon, M, Sironi, G, Valsecchi, M, Mastronuzzi, A, Terenziani, Monica, Tozzi, Alberto Eugenio, Diaco, Laura, Biasin, Eleonora, Cattoni, Alessandro, Croci, Ileana, Fraschini, Donatella, Giorgiani, Giovanna, Haupt, Riccardo, Muraca, Monica, Pillon, Marta, Sironi, Giovanna, Valsecchi, Maria Grazia, Mastronuzzi, Angela, Terenziani, M, Tozzi, A, Diaco, L, Biasin, E, Cattoni, A, Croci, I, Fraschini, D, Giorgiani, G, Haupt, R, Muraca, M, Pillon, M, Sironi, G, Valsecchi, M, Mastronuzzi, A, Terenziani, Monica, Tozzi, Alberto Eugenio, Diaco, Laura, Biasin, Eleonora, Cattoni, Alessandro, Croci, Ileana, Fraschini, Donatella, Giorgiani, Giovanna, Haupt, Riccardo, Muraca, Monica, Pillon, Marta, Sironi, Giovanna, Valsecchi, Maria Grazia, and Mastronuzzi, Angela

Abstract

Introduction: Quality of life in childhood cancer survivors is largely affected by survivorship care and transition from treatment to long-term follow-up (LTFU). Referring to evidence-based recommendations, we wanted to evaluate LTFU care for survivors through a survey among the Italian Association for Pediatric Hematology-Oncology (AIEOP) centers. The project aimed to evaluate the availability of services in Italy, investigate strengths and weaknesses, analyze improvements of awareness in the field, and identify the gaps that need to be addressed by different centers. Methods: Together with the family representatives, on behalf of AIEOP’s Late Effects Working Group, we developed a questionnaire on assisting childhood cancer survivors. All AIEOP centers received one questionnaire including information on local health system organizations; LTFU for childhood cancer survivors; services for adult survivors of childhood cancer; information provided to survivors/caregivers and care plan delivery. Results: Forty-eight AIEOP centers were contacted and 42 replied, with a response rate of 87.5%. The majority of respondents confirmed their interest in assisting patients with a survivorship care plan (95.2%), regardless of a clinic or dedicated staff. Discussion: This is the first overview of LTFU in Italy, which provides detailed results at national levels, prompting consideration of improvements in the last decade. Although there is a high level of interest in survivorship care, many centers lack resources to implement such programs. The identification of these challenges is useful for planning future strategies.

Published
2023

34. Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance

Author

Corinaldesi, Clarissa, Holmes, Antony B., Martire, Gaia, Tosato, Anna, Rizzato, Domenico, Lovisa, Federica, Gallingani, Ilaria, Shen, Qiong, Ferrone, Lavinia, Harris, Marian, Davies, Kimberly, Molinaro, Luca, Mortara, Umberto, Dei Tos, Angelo Paolo, Ofori, Kenneth, D’Amore, Emanuele S. G., Chiarle, Roberto, Ngan, Bo, Carraro, Elisa, Pillon, Marta, Hussein, Shafinaz, Bhagat, Govind, Pizzi, Marco, Mussolin, Lara, and Basso, Katia

Abstract

Burkitt lymphoma (BL) is the most frequent B-cell lymphoma in pediatric patients. While most patients are cured, a fraction of them are resistant to therapy. To investigate BL heterogeneity and the features distinguishing therapy responders (R) from non-responders (NR), we analyzed by single-cell (sc)-transcriptomics diagnostic EBV-negative BL specimens. Analysis of the non-tumor component revealed a predominance of immune cells and a small representation of fibroblasts, enriched in NR. Tumors displayed patient-specific features, as well as shared subpopulations that expressed transcripts related to cell cycle, signaling pathways and cell-of-origin signatures. Several transcripts were differentially expressed in R versus NR. The top candidate, Tropomyosin 2 (TPM2), a member of the tropomyosin actin filament binding protein family, was confirmed to be significantly higher in NR both at the transcript and protein level. Stratification of patients based on TPM2 expression at diagnosis significantly correlated with prognosis, independently of TP53mutations. These results indicate that BL displays transcriptional heterogeneity and identify candidate biomarkers of therapy resistance.

Published
2024
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36. Autoimmune Lymphoproliferative Syndrome (ALPS) Disease and ALPS Phenotype: Are They Two Distinct Entities?

Author

Palmisani, Elena, primary, Miano, Maurizio, additional, Grossi, Alice, additional, Lanciotti, Marina, additional, Lupia, Michela, additional, Terranova, Paola, additional, Ceccherini, Isabella, additional, Montanari, Eugenia, additional, Calvillo, Michaela, additional, Pierri, Filomena, additional, Micalizzi, Concetta, additional, Maggiore, Rosario, additional, Guardo, Daniela, additional, Zanardi, Sabrina, additional, Facchini, Elena, additional, Maggio, Angela, additional, Mastrodicasa, Elena, additional, Corti, Paola, additional, Russo, Giovanna, additional, Pillon, Marta, additional, Farruggia, Piero, additional, Cesaro, Simone, additional, Barone, Angelica, additional, Tosetti, Francesca, additional, Ramenghi, Ugo, additional, Crescenzio, Nicoletta, additional, Bleesing, Jack, additional, Dufour, Carlo, additional, and Fioredda, Francesca, additional

Published
2023
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37. [18F]FDG PET-MR in the Evaluation and Follow-Up of Incidental Bone Ischemic Lesions in a Mono-Center Cohort of Pediatric Patients Affected by Hodgkin’s Lymphoma

Author

Giraudo, Chiara, primary, Carraro, Elisa, additional, Cavallaro, Elena, additional, Zuliani, Monica, additional, Spampinato Gotsyak, Liliya, additional, Massano, Davide, additional, Modugno, Antonella, additional, Mussolin, Lara, additional, Biffi, Alessandra, additional, Cecchin, Diego, additional, Pillon, Marta, additional, and Zucchetta, Pietro, additional

Published
2023
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39. Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP)

Author

Barone, Angelica, Lucarelli, Annunziata, Onofrillo, Daniela, Verzegnassi, Federico, Bonanomi, Sonia, Cesaro, Simone, Fioredda, Francesca, Iori, Anna Paola, Ladogana, Saverio, Locasciulli, Anna, Longoni, Daniela, Lanciotti, Marina, Macaluso, Alessandra, Mandaglio, Rosalba, Marra, Nicoletta, Martire, Baldo, Maruzzi, Matteo, Menna, Giuseppe, Notarangelo, Lucia Dora, Palazzi, Giovanni, Pillon, Marta, Ramenghi, Ugo, Russo, Giovanna, Svahn, Johanna, Timeus, Fabio, Tucci, Fabio, Cugno, Chiara, Zecca, Marco, Farruggia, Piero, Dufour, Carlo, and Saracco, Paola

Published
2015
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40. Current practices of follow-up programs for childhood cancer survivors in Italy

Author

Terenziani, Monica, Tozzi, Alberto Eugenio, Diaco, Laura, Biasin, Eleonora, Cattoni, Alessandro, Croci, Ileana, Fraschini, Donatella, Giorgiani, Giovanna, Haupt, Riccardo, Muraca, Monica, Pillon, Marta, Sironi, Giovanna, Valsecchi, Maria Grazia, Mastronuzzi, Angela, Terenziani, M, Tozzi, A, Diaco, L, Biasin, E, Cattoni, A, Croci, I, Fraschini, D, Giorgiani, G, Haupt, R, Muraca, M, Pillon, M, Sironi, G, Valsecchi, M, and Mastronuzzi, A

Subjects
childhood cancer survivor, long-term follow-up, Survey
Abstract

Introduction: Quality of life in childhood cancer survivors is largely affected by survivorship care and transition from treatment to long-term follow-up (LTFU). Referring to evidence-based recommendations, we wanted to evaluate LTFU care for survivors through a survey among the Italian Association for Pediatric Hematology-Oncology (AIEOP) centers. The project aimed to evaluate the availability of services in Italy, investigate strengths and weaknesses, analyze improvements of awareness in the field, and identify the gaps that need to be addressed by different centers. Methods: Together with the family representatives, on behalf of AIEOP's Late Effects Working Group, we developed a questionnaire on assisting childhood cancer survivors. All AIEOP centers received one questionnaire including information on local health system organizations; LTFU for childhood cancer survivors; services for adult survivors of childhood cancer; information provided to survivors/caregivers and care plan delivery. Results: Forty-eight AIEOP centers were contacted and 42 replied, with a response rate of 87.5%. The majority of respondents confirmed their interest in assisting patients with a survivorship care plan (95.2%), regardless of a clinic or dedicated staff. Discussion: This is the first overview of LTFU in Italy, which provides detailed results at national levels, prompting consideration of improvements in the last decade. Although there is a high level of interest in survivorship care, many centers lack resources to implement such programs. The identification of these challenges is useful for planning future strategies.

Published
2023

41. sj-pdf-1-tmj-10.1177_03008916231185981 – Supplemental material for Current practices of follow-up programs for childhood cancer survivors in Italy

Author

Terenziani, Monica, Tozzi, Alberto Eugenio, Diaco, Laura, Biasin, Eleonora, Cattoni, Alessandro, Croci, Ileana, Fraschini, Donatella, Giorgiani, Giovanna, Haupt, Riccardo, Muraca, Monica, Pillon, Marta, Sironi, Giovanna, Valsecchi, Maria Grazia, and Mastronuzzi, Angela

Subjects
Medicine
Abstract

Supplemental material, sj-pdf-1-tmj-10.1177_03008916231185981 for Current practices of follow-up programs for childhood cancer survivors in Italy by Monica Terenziani, Alberto Eugenio Tozzi, Laura Diaco, Eleonora Biasin, Alessandro Cattoni, Ileana Croci, Donatella Fraschini, Giovanna Giorgiani, Riccardo Haupt, Monica Muraca, Marta Pillon, Giovanna Sironi, Maria Grazia Valsecchi and Angela Mastronuzzi in Tumori Journal

Published
2023
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42. Correction: Long-term outcome after allogeneic hematopoietic stem cell transplantation for Shwachman–Diamond syndrome: a retrospective analysis and a review of the literature by the Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation (SAAWP-EBMT)

Author

Cesaro, Simone, Pillon, Marta, Sauer, Martin, Smiers, Frans, Faraci, Maura, de Heredia, Cristina Diaz, Wynn, Robert, Greil, Johann, Locatelli, Franco, Veys, Paul, Uyttebroeck, Anne, Ljungman, Per, Chevalier, Patrice, Ansari, Marc, Badell, Isabel, Güngör, Tayfun, Salim, Rahuman, Tischer, Johanna, Tecchio, Cristina, Russell, Nigel, Chybicka, Alicja, Styczynski, Jan, Krivan, Gergely, Smith, Owen, Stein, Jerry, Afanasyev, Boris, Pochon, Cécile, Menconi, Maria Cristina, Bosman, Paul, Mauro, Margherita, Tridello, Gloria, de Latour, Regis Peffault, and Dufour, Carlo

Published
2020
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43. Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma

Author

Beishuizen, Auke, Mellgren, Karin, Andrés, Mara, Auperin, Anne, Bacon, Chris M, Bomken, Simon, Burke, GA Amos, Burkhardt, Birgit, Brugieres, Laurence, Chiang, Alan KS, Damm-Welk, Christine, d'Amore, Emanuele, Horibe, Keizo, Kabickova, Edita, Khanam, Tasneem, Kontny, Udo, Klapper, Wolfram, Lamant, Laurence, Le Deley, Marie-Cecile, Loeffen, Jan, Macintyre, Elizabeth, Mann, Georg, Meyer-Wentrup, Friederike, Michgehl, Ulf, Minard-Colin, Veronique, Mussolin, Lara, Oschlies, Ilske, Patte, Catherine, Pillon, Marta, Reiter, Alfred, Rigaud, Charlotte, Roncery, Leila, Salaverria, Itziar, Simonitsch-Klupp, Ingrid, Uyttebroeck, Anne, Verdu-Amoros, Jaime, Williams, Denise, Woessmann, Wilhelm, Wotherspoon, Andrew, Wrobel, Grazyna, Zimmermann, Martin, Attarbaschi, Andishe, Turner, Suzanne D, European Intergroup for Childhood Non-Hodgkin Lymphoma, Turner, Suzanne [0000-0002-8439-4507], and Apollo - University of Cambridge Repository

Subjects
Europe, Young Adult, Lymphoma, Non-Hodgkin, Humans, Child
Abstract

The European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) was established 25 years ago with the goal to facilitate clinical trials and research collaborations in the field both within Europe and worldwide. Since its inception, much progress has been made whereby major improvements in outcomes have been achieved. In this Review, we describe the different diagnostic entities of non-Hodgkin lymphoma in children and young adults describing key features of each entity and outlining clinical achievements made in the context of the EICNHL framework. Furthermore, we provide an overview of advances in biopathology with an emphasis on the role of biological studies and how they have shaped available treatments. Finally, for each entity, we describe future goals, upcoming clinical trials, and highlight areas of research that require our focus going forward.

Published
2022
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45. Phenotype and Natural History of ELANE and NON ELANE Severe Congenital Neutropenia in Italy: Data from the National Registry

Author

Fioredda, Francesca, primary, Zanardi, Sabrina, additional, Fragola, Martina, additional, Lanciotti, Marina, additional, Casartelli, Pietro, additional, Zuccoli, Caterina, additional, Marinoni, Maddalena, additional, Finocchi, Andrea, additional, Saettini, Francesco, additional, Bonanomi, Sonia, additional, Verzegnassi, Federico, additional, Pillon, Marta, additional, Marzollo, Antonio, additional, Barone, Angelica, additional, Mastrodicasa, Elena, additional, Onofrillo, Daniela, additional, Luti, Laura, additional, Cesaro, Simone, additional, Giacomazzi, Alice, additional, Farinasso, Loredana, additional, Licciardello, Maria, additional, Russo, Giovanna, additional, Martire, Baldassarre, additional, Menna, Giuseppe, additional, Barella, Susanna, additional, Piroddi, Antonio, additional, Cuzzubbo, Daniela, additional, Veltroni, Marinella, additional, Boscarol, Gianluca, additional, Palazzi, Giovanni, additional, Tovaglieri, Nicola, additional, Petrone, Angela, additional, Farruggia, Piero, additional, Guarina, Angela, additional, Caracchia, Giulia, additional, Notarangelo, LuciaDora, additional, and Dufour, Carlo, additional

Published
2022
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47. Quantitative Plasma Proteomics to Identify Candidate Biomarkers of Relapse in Pediatric/Adolescent Hodgkin Lymphoma

Author

Repetto, Ombretta, primary, Caggiari, Laura, additional, De Zorzi, Mariangela, additional, Elia, Caterina, additional, Mussolin, Lara, additional, Buffardi, Salvatore, additional, Pillon, Marta, additional, Muggeo, Paola, additional, Casini, Tommaso, additional, Steffan, Agostino, additional, Mauz-Körholz, Christine, additional, Mascarin, Maurizio, additional, and De Re, Valli, additional

Published
2022
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48. Pediatric Precursor B-Cell Lymphoblastic Malignancies: From Extramedullary to Medullary Involvement

Author

Kroeze, Emma, primary, Arias Padilla, Laura, additional, Bakker, Max, additional, Boer, Judith M., additional, Hagleitner, Melanie M., additional, Burkhardt, Birgit, additional, Mori, Takeshi, additional, Attarbaschi, Andishe, additional, Verdú-Amorós, Jaime, additional, Pillon, Marta, additional, Anderzhanova, Liliya, additional, Kabíčková, Edita, additional, Chiang, Alan K. S., additional, Kebudi, Rejin, additional, Mellgren, Karin, additional, Lazic, Jelena, additional, Jazbec, Janez, additional, Meijerink, Jules P. P., additional, Beishuizen, Auke, additional, and Loeffen, Jan L. C., additional

Published
2022
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49. Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia

Author

Veltri, Giulia, primary, Lovisa, Federica, additional, Cortese, Giuliana, additional, Pillon, Marta, additional, Carraro, Elisa, additional, Cesaro, Simone, additional, Provenzi, Massimo, additional, Buffardi, Salvatore, additional, Francescato, Samuela, additional, Biffi, Alessandra, additional, Buldini, Barbara, additional, Conter, Valentino, additional, Serafin, Valentina, additional, and Mussolin, Lara, additional

Published
2022
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