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1. Supplementary Figures 1 - 6 from Threshold Levels of ABL Tyrosine Kinase Inhibitors Retained in Chronic Myeloid Leukemia Cells Determine Their Commitment to Apoptosis

Author

Brian J. Druker, Michael W. Deininger, Jeffrey W. Tyner, John Apgar, Dennis R. Koop, Kurt W. Vogel, Bryan D. Marks, Steven M. Riddle, Jenny Luo, Huihong You, Kara J. Johnson, Dorian H. LaTocha, Ryan J. MacKenzie, Matthew S. Zabriskie, Lauren T. Adrian, Anupriya Agarwal, Christopher A. Eide, and Thomas O'Hare

Abstract

PDF file - 1469K, Different ABL TKIs demonstrate potency differences in relative cellular and biochemical target inhibition (S1); Incomplete restoration of BCR-ABL signaling activity following washout of dasatinib or ponatinib tracks with intracellular drug retention and commitment to apoptosis in LAMA cells (S2); Incomplete restoration of BCR-ABL signaling activity following washout of nilotinib, imatinib, or DCC-2036 tracks with intracellular drug retention and commitment to apoptosis in LAMA cells (S3); BCR-ABL signaling is partially attenuated in conditions of continuous low concentrations of ABL TKIs that induce apoptosis (S4); Commitment to apoptosis in primary CML cells tracks with intracellular retention of ABL TKIs (S5); Intracellular retention of dasatinib, nilotinib, and imatinib is reduced following washout in primary CML cells harboring the resistant BCR-ABLT315I mutant (S6).

Published
2023
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2. Supplementary Tables 1 - 2 from Threshold Levels of ABL Tyrosine Kinase Inhibitors Retained in Chronic Myeloid Leukemia Cells Determine Their Commitment to Apoptosis

Author

Brian J. Druker, Michael W. Deininger, Jeffrey W. Tyner, John Apgar, Dennis R. Koop, Kurt W. Vogel, Bryan D. Marks, Steven M. Riddle, Jenny Luo, Huihong You, Kara J. Johnson, Dorian H. LaTocha, Ryan J. MacKenzie, Matthew S. Zabriskie, Lauren T. Adrian, Anupriya Agarwal, Christopher A. Eide, and Thomas O'Hare

Abstract

PDF file - 337K, Summary of mean fluorescence intensity values for levels of CrkL and STAT5 phosphorylation in K562 cells following acute ABL TKI exposure followed by standard and expanded washout (S1); Kinase:inhibitor dissociation off-rates for ABL TKIs (S2).

Published
2023
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3. Supplementary Figure Legend from Threshold Levels of ABL Tyrosine Kinase Inhibitors Retained in Chronic Myeloid Leukemia Cells Determine Their Commitment to Apoptosis

Author

Brian J. Druker, Michael W. Deininger, Jeffrey W. Tyner, John Apgar, Dennis R. Koop, Kurt W. Vogel, Bryan D. Marks, Steven M. Riddle, Jenny Luo, Huihong You, Kara J. Johnson, Dorian H. LaTocha, Ryan J. MacKenzie, Matthew S. Zabriskie, Lauren T. Adrian, Anupriya Agarwal, Christopher A. Eide, and Thomas O'Hare

Abstract

PDF file - 45K

Published
2023
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4. A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.

Author

Kara J Johnson, Ian J Griswold, Thomas O'Hare, Amie S Corbin, Marc Loriaux, Michael W Deininger, and Brian J Druker

Subjects
Medicine, Science
Abstract

The BCR-ABL tyrosine kinase is the defining feature of chronic myeloid leukemia (CML) and its kinase activity is required for induction of this disease. Current thinking holds that BCR-ABL forms a multi-protein complex that incorporates several substrates and adaptor proteins and is stabilized by multiple direct and indirect interactions. Signaling output from this highly redundant network leads to cellular transformation. Proteins known to be associated with BCR-ABL in this complex include: GRB2, c-CBL, p62(DOK), and CRKL. These proteins in turn, link BCR-ABL to various signaling pathways indicated in cellular transformation. In this study we show that a triple mutant of BCR-ABL with mutations of the direct binding sites for GRB2, CBL, p62(DOK) and CRKL, is defective for transformation of primary hematopoietic cells in vitro and in a murine CML model, while it retains the capacity to induce IL-3 independence in 32D cells. Compared to BCR-ABL, the triple mutant's ability to activate the MAP kinase and PI3-kinase pathways is severely compromised, while STAT5 phosphorylation is maintained, suggesting that the former are crucial for the transformation of primary cells, but dispensable for transformation of factor dependent cell lines. Our data suggest that inhibition of BCR-ABL-induced leukemia by disrupting protein interactions could be possible, but would require blocking of multiple sites.

Published
2009
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5. Order Set to Improve the Care of Patients Hospitalized for an Exacerbation of Chronic Obstructive Pulmonary Disease

Author

Beth M. DeRonne, Connie M. Parenti, Kirstin E. Brown, Kara J. Johnson, and Kathryn L. Rice

Subjects
Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Exacerbation, Minnesota, Pulmonary disease, Inappropriate Prescribing, Medical Order Entry Systems, Order entry, 03 medical and health sciences, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Primary outcome, Electronic health record, Adrenal Cortex Hormones, medicine, Humans, 030212 general & internal medicine, Intensive care medicine, Aged, Aged, 80 and over, COPD, business.industry, Disease progression, Length of Stay, Middle Aged, medicine.disease, Quality Improvement, Anti-Bacterial Agents, Bronchodilator Agents, 030228 respiratory system, Disease Progression, Female, Guideline Adherence, business, Order set
Abstract

Physicians' adherence to prescribing evidence-based inpatient and outpatient therapies for chronic obstructive pulmonary disease (COPD) is low, and there is a paucity of information about the utility of admission order sets for patients with COPD exacerbations.To determine if implementation of a locally designed, evidence-based, multidisciplinary computer physician order entry set in the electronic health record improves the quality of physician pharmacologic prescribing for patients hospitalized for COPD exacerbations.This study was performed before and after implementation of a computerized order set for patients hospitalized for COPD exacerbations. The primary outcome was the rate of zero prescribing errors by physicians for inpatient and discharge drugs for COPD over a 1-year period before implementation and for 6 months after implementation. Errors were defined as no therapy or inappropriate therapy in the following categories: antibiotic, systemic corticosteroid, short-acting bronchodilator, long-acting bronchodilator, and inhaled corticosteroid. Secondary outcomes included mean physician pharmaceutical prescribing error rate; types of errors; hospital lengths of stay; and unscheduled physician visits, emergency department visits, rehospitalizations, and deaths within 30 days from discharge.There were 194 COPD exacerbation admissions during the 1-year preimplementation period and 81 admissions during the 6-month postimplementation period. Compared with the preimplementation period, the percentage of patients receiving all recommended pharmacologic therapies for the 6 months after implementation increased from 18.6% to 54.3% (P 0.001). The mean number of errors decreased from 1.76 to 0.65 (P 0.001). Antibiotic and systemic corticosteroid errors decreased from 39% to 16% (P 0.001) and from 58% to 28% (P 0.001), respectively. Fewer patients were discharged without a short-acting bronchodilator (13.9% vs. 2.5%; P = 0.005), a long-acting bronchodilator (16.5% vs. 7.4%; P = 0.047), or inhaled corticosteroid (18% vs. 9.9%; P = 0.089). Improvements were sustained over the 6-month postimplementation period. Hospital length of stay decreased from 4 (±3) days preimplementation to 2.9 (±1.9) days postimplementation (P = 0.002). There were no significant differences in 30-day clinical outcomes, including the rates of unscheduled physician or emergency department visits, rehospitalizations, or deaths.Computerized multidisciplinary admission order set implementation for patients hospitalized for a COPD exacerbation improved physicians' adherence to evidence-based pharmacologic treatment, and they were associated with reductions in length of hospital stay.

Published
2016

7. Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients

Author

Barbara J.S. Sanderson, Kara J. Johnson, and W. David Henner

Subjects
Adult, Multiple Sclerosis, Time Factors, Cyclophosphamide, Health, Toxicology and Mutagenesis, Lymphocyte, Mutant, DNA Mutational Analysis, Pharmacology, Toxicology, chemistry.chemical_compound, In vivo, Genetics, Medicine, Humans, Lymphocytes, Antineoplastic Agents, Alkylating, Genetics (clinical), Thionucleosides, Chlorambucil, Dose-Response Relationship, Drug, Guanosine, business.industry, Middle Aged, Nitrogen mustard, Dose–response relationship, medicine.anatomical_structure, chemistry, Immunology, Toxicity, Mutation, business, medicine.drug, Mutagens
Abstract

Monitoring patients treated with single antineoplastic agents is aiding our understanding of what hazard these drugs pose in vivo. In this study, the frequency of mutant 6-thioguanine-resistant (TG(R)) peripheral blood lymphocytes was monitored before treatment and for < or =35 weeks after treatment of patients with cyclophosphamide (CP) or chlorambucil (CAB). The mean mutant frequency before treatment for six multiple sclerosis patients treated with high-dose CP was 2.53 x 10(-5) and increased after treatment to 4.61 x 10(-5) (P = 0.08, paired t-test). Using each patient as their own control, there were significant increases (each at P < 0.04) detectable within 2-4 weeks in four of the multiple sclerosis patients treated with CP. There was no increase in an untreated control monitored over the same period. In a patient receiving five sequential CP treatments at 1 month intervals, there were cumulative increases in the frequency of mutant cells. The mutant frequency increased from 0.31 x 10(-5) before treatment to 3.64 x 10(-5) after the final treatment and had decreased to 0.53 x 10(-5) at 35 weeks after treatment. In one of two CAB-treated patients with indolent non-Hodgkin's lymphoma, there was a significant increase in mutant frequency (P < 0.03) after treatment. Freshly isolated peripheral blood lymphocytes treated with 4-hydroperoxy-CP in vitro demonstrate a dose-dependent increase in mutant frequency. The increment in mutant frequency observed in vivo is of the order expected from the in vitro experiments. Although this study demonstrates that single or multiple doses of a single antineoplastic agent are mutagenic in vivo for some patients, further studies are needed to determine the extent and mechanism of the inter-individual variations in mutagenic response.

Published
2001

8. Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells

Author

Barbara J. S. Sanderson, Kara J. Johnson, W. David Henner, and T. R. Skopek

Subjects
Melphalan, Male, endocrine system, Alkylating Agents, Hypoxanthine Phosphoribosyltransferase, Epidemiology, Cell Survival, Health, Toxicology and Mutagenesis, Antineoplastic Agents, Pharmacology, Biology, Cell Line, chemistry.chemical_compound, medicine, Humans, Cytotoxicity, Genetics (clinical), Carcinogen, Carmustine, B-Lymphocytes, Chlorambucil, Mutagenicity Tests, Antineoplastic Alkylating Agent, Lymphoblast, fungi, food and beverages, Nitrogen mustard, Biochemistry, chemistry, Carcinogens, medicine.drug, Mutagens
Abstract

The alkylating agents in clinical use as antineoplastics are strongly implicated as human carcinogens on the basis of animal studies and human epidemiologic studies. However, there is little quantitative information on the extent to which exposure to these drugs is mutagenic for normal (non-malignant) cells and the extent to which such mutagenicity correlates with cytotoxicity of these agents. Human lymphoblastoid cells (WIL2-NS) were exposed to graded doses of eight antineoplastic alkylating agents. Cell killing and mutation induction at the hypoxanthine -guanine phosphoribosyltransferase (HPRT) locus were measured by cloning in microplates in the presence and absence of 6-thioguanine. Dose-dependent decreases in survival were used to calculate IC50s for each of the drugs tested. The IC50s, for 1 hr exposure, ranged from 4 x 10(-7) M for nitrogen mustard to 5 x 10(-4) M for busulfan. The eight drugs tested each induced detectable increases in the frequency of mutant cells. The mutagenicity of these agents is correlated strongly with cytotoxicity. However, at equitoxic doses (IC50), the frequency of induced mutants ranged from approximately 3 x 10(-6) for 1,3-bis(2-chlorethyl)-1-nitrosourea (BCNU) to 2 x 10(-5) for busulfan and cisplatin. These results quantitate the dose-dependent cytotoxic and mutagenic effects of these bifunctional alkylating agents on human cells. All are cytotoxic and mutagenic, although their mutagenic efficiency varies.

Published
1991

10. The role of proteases in epithelial-to-mesenchymal cell transitions in cancer.

Author

Mitschke, Julia, Burk, Ulrike C., and Reinheckel, Thomas

Abstract

Changing the characteristics of cells from epithelial states to mesenchymal properties is a key process involved in developmental and physiological processes as well as in many diseases with cancer as the most prominent example. Nowadays, a great deal of work and literature concerns the understanding of the process of epithelial-to-mesenchymal transition (EMT) in terms of its molecular regulation and its implications for cancer. Similar statements can certainly be made regarding the investigation of the more than 500 proteases typically encoded by a mammalian genome. Specifically, the impact of proteases on tumor biology has been a long-standing topic of interest. However, although EMT actively regulates expression of many proteases and proteolytic enzymes are clearly involved in survival, division, differentiation, and movements of cells, information on the diverse roles of proteases in EMT has been rarely compiled. Here we aim to conceptually connect the scientific areas of "EMT" and "protease" research by describing how several important classes of proteolytic enzymes are regulated by EMT and how they are involved in initiation and execution of the EMT program. To do so, we briefly introduce the evolving key features of EMT and its regulation followed by discussion of protease involvement in this process. [ABSTRACT FROM AUTHOR]

Published
2019
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11. The Career Development Initiative: 2011-2012 Member Service Project Off to a Great Start.

Author

Johnson, Kara J.

Subjects
CAREER development, SERVICES for lawyers, LEGAL professions
Abstract

The article presents information on the Career Development Initiative (CDI) of the American Bar Association Young Lawyers' Division (ABA YLD). The CDI programming is co-sponsored and developed with the help of the ABA Career Center. The CDI is intended to develop different aspects of a young lawyer's career.

Published
2011

12. Tips for Keeping Your Membership Active in Metropolitan Free Areas: Advice from Rural Affiliates.

Author

Johnson, Kara J.

Subjects
MEMBERSHIP in associations, institutions, etc., LAWYERS, RURAL geography, LEADERSHIP
Abstract

The author offers advice to statewide affiliates of the American Bar Association (ABA) on how to keep their states' memberships active in rural areas. She suggests allowing young lawyers in rural areas to actively participate in statewide leadership to enable them to voice their opinions for realistic programming throughout the state. A discussion on how to promote awareness among young lawyers of programming from other bar organizations is given.

Published
2011

13. New Lawyer Bootcamp Series: Basic Training for Lawyers.

Author

Johnson, Kara J.

Subjects
CONFERENCES & conventions
Abstract

The article offers information on the New Lawyer Bootcamp event to be held during the American Bar Association (ABA) Midyear Meeting in Atlanta, Georgia on February 11, 2011.

Published
2011

14. Is birth weight associated with childhood lymphoma? A meta-analysis.

Author

Papadopoulou, C., Antonopoulos, C. N., Sergentanis, T. N., Panagopoulou, P., Belechri, M., and Petridou, E. T.

Abstract

Several risk factors have been identified for childhood lymphomas. The purpose of this meta-analysis was to synthesize current evidence regarding the association between birth weight with primarily the risk for non-Hodgkin lymphoma (NHL), given its similarity to acute lymphoblastic leukemia, Hodgkin lymphoma (HL) and any category of lymphoma. Two cohort (278,751 children) and seven case-control studies (2,660 cases and 69,274 controls) were included. Effects estimates regarding NHL, HL and any lymphoma were appropriately pooled using fixed or random effects model in two separate analyses: specifically, high was compared to normal or any birth weight. Similarly, low was compared to normal or any birth weight. No statistically significant association was found between high birth weight, as compared to normal birth weight, and risk for NHL plus Burkitt lymphoma (OR = 1.17, 95% CI = 0.76-1.80, random effects), HL (OR = 0.94, 95% CI = 0.64-1.38, fixed effects) or any plus Burkitt lymphoma (OR = 1.09, 95% CI = 0.76-1.56, fixed effects). A null association emerged when low was compared with normal birth weight for NHL plus Burkitt lymphoma (OR = 1.07, 95% CI = 0.71-1.62, random effects), HL (OR = 0.94, 95% CI = 0.54-1.65, fixed effects) or any plus Burkitt lymphoma (OR = 1.02, 95% CI = 0.79-1.33, fixed effects). Accordingly, no association was found when high or low birth weight was compared to any birth weight. Although current evidence suggests no association, birth weight might be a too crude indicator to reveal a genuine association of fetal growth with specific lymphoma categories; hence, there is an emerging need for use of more elaborate proxies, at least those accounting for gestational week. [ABSTRACT FROM AUTHOR]

Published
2012
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15. 2013 Spring Conference: Double the Fun in the Twin Cities.

Author

Johnson, Kara J.

Subjects
CONFERENCES & conventions
Abstract

The article offers information on the American Bar Association Young Lawyers Division's (ABA YLD) Spring Conference to be held in Minneapolis, Minnesota on May 16-18, 2013.

Published
2013

16. Legal Lollapalooza: ABA YLD Hits Chicago for Annual Meeting.

Author

Johnson, Kara J.

Subjects
CONFERENCES & conventions, SERVICES for veterans, LEGAL services
Abstract

The article discusses the highlights of the Annual Meeting of the American Bar Association (ABA) held in Chicago, Illinois on August 2 to 4, 2012. During the conference, U.S. Circuit Court Judge Anne Claire Williams spoke on the importance of diversity and the impacts that people have on each other's lives. The ABA also honored the Young Lawyers Division for its efforts to help the legal needs of war veterans at the Jesse Brown Veterans Administration Medical Center.

Published
2012

17. Mentorship Programs: What Works and What Doesn't.

Author

Johnson, Kara J.

Subjects
MENTORING, TRAINING of lawyers, LAW schools, PARTICIPATION, MENTORS
Abstract

The article offers information on mentorship programs in law school and young lawyers in the U.S. It says that mentorship program becomes unsuccessful because of lack of participation and lack of continuing participation between mentors and mentee. It mentions three approaches taken successfully in the country due to the involvement of respective affiliates including laid-back programs, group mentorship programs and one-on-one mentorship programs.

Published
2012

18. Affiliate Spotlight: The ABA YLD's Affiliated Minority Bar Associations.

Author

Johnson, Kara J.

Subjects
BAR associations, MEETINGS
Abstract

The article discusses the activities of national minority bar associations which are affiliated with the American Bar Association (ABA) Young Lawyers Division (YLD). The National Asian Pacific American Bar Association (NAPABA) held its 23rd Annual Convention in Atlanta, Georgia on November 17-20, 2011. Meanwhile, the Young Lawyers Division of the National Bar Association will hold its mid-winter meeting in St. Martin on January 18-22, 2012.

Published
2012

19. The Affiliate Showcase: Promoting Outstanding Affiliate Projects.

Author

Huitink, Daniel W. and Johnson, Kara J.

Subjects
CONFERENCES & conventions, LAWYERS, VOLUNTEERS
Abstract

The article reports on the Affiliate Showcase (AS), a part of the May 2011 American Bar Association Young Lawyers Division Spring Conference. It says AS featured public and member service projects and initiatives from affiliated young lawyer organizations in the U.S. and abroad. It cites the Oregon New Lawyers Division's initiative that helps unemployed attorneys find legal volunteer opportunities in their areas, and the Dallas Association of Young Lawyer's Community Courts for the homeless.

Published
2011

20. The New Partner and In-House Counsel Conference: A Successful Kickoff to a New Event.

Author

Johnson, Kara J.

Subjects
PHILADELPHIA (Pa.), PENNSYLVANIA, AMERICAN Bar Association. Young Lawyers Division, FOUR Seasons Hotels Inc., WOLFE, David
Abstract

The article discusses the highlights of the first New Partner and In-House Counsel Conference of the American Bar Association Young Lawyers Division (ABA YLD) which was held at the Four Seasons Hotel in Philadelphia, Pennsylvania. The welcome address was delivered by David Wolfe, chairman of ABA YLD, while Comcast Corp. General Counsel Art Block provided the keynote address. The event's closing joint session focused on the interactions and experiences of law firm partners and in-house counsel.

Published
2011

21. Affiliate Leader Spotlight: David Veile.

Author

Johnson, Kara J.

Subjects
BAR associations, LAWYERS
Abstract

The article features affiliate David Veile, vice-president of the Tennessee Bar Association Young Lawyers Division and will be President-Elect in 2012 and Tennessee Young Lawyers president in 2012-2013. It presents a brief biography and career path of Veile who first worked with the Metropolitan Nashville Police Department as police officer before studying at law school, his law practice and leadership. It mentions the current law practice of Veile at Lowery, Lowery & Cherry in Lebanon, Tennessee and his focus on criminal defense and family law.

Published
2011

22. The Affiliate Assistance Team: What Can It Actually Do to Help Your Affiliate?

Author

Johnson, Kara J.

Subjects
EMAIL systems, LAWYERS, CONFERENCES & conventions
Abstract

The article offers information on the Affiliate Assistance Team (AAT), how to request for assistance and ways through which affiliates can be assisted by AAT. Several ways to request for AAT assistance include contacting AAT or sending an electronic mail (e-mail) to AAT Director Kimber Gallo while help extended to affiliates include answering questions about conferences, securing funding and locating resources for conferences. It mentions the current projects of AAT including organizing the Colorado and Wyoming "Young Lawyer Leadership Roundtable."

Published
2011

23. Honoring Our Legal Heroes: Outstanding Young Military Lawyer Awards.

Author

Johnson, Kara J.

Subjects
MILITARY lawyers, BAR associations, AWARDS
Abstract

The article announces the winners of the Outstanding Young Military Lawyer Awards given by the American Bar Association Young Lawyers Division (ABA YLD) in 2010, including Captain Stephanie Cooper, Lieutenant Christopher P. Toscano and Captain Naomi N. Porterfield.

Published
2010

24. Leadership Spotlight: New York State Bar's Outstanding Young Lawyer--Joseph M. Hanna.

Author

Johnson, Kara J.

Subjects
LAWYERS, AWARDS, NONPROFIT organizations, LEADERSHIP, ASSOCIATIONS, institutions, etc.
Abstract

The article features lawyer Joseph M. Hanna, 2010 recipient of the Outstanding Young Lawyer Award from the New York State Bar Association. His philanthropic efforts were highlighted through his nonprofit charity Bunkers in Baghdad, which sends golf equipment to U.S. troops in Iraq and Afghanistan. As chair and organizer of the professional networking event Success in the City, he showed his leadership and professional development skills. It cites other organizations with which Hanna is actively involved.

Published
2010

28. Next Steps Challenge Season Two: A Second Successful Year.

Author

Johnson, Kara J.

Subjects
DIVERSITY in organizations, LEGAL professions, LEGAL conferences, BAR associations, CONFERENCES & conventions
Abstract

The article discusses the highlights of the American Bar Association Young (ABA) Lawyers Division's (YLD) Next Steps Challenge program held at the association's 2013 Spring Conference in Minneapolis, Minnesota in May 2013. The program was created with the aim of increasing the diversity in the pipeline to the legal profession and in response to a two-year ABA Presidential Initiative that examined diversity in the legal profession.

Published
2013

29. 2012--2013 Incoming ABA President: Laurel Bellows.

Author

Johnson, Kara J.

Subjects
LEGAL conferences, CAREER development
Abstract

An interview with American Bar Association (ABA) President Laurel Bellows is presented. She discusses her engagements in ABA including Chicago Bar Association's former president and active participation with the National Conference of Bar Presidents. Attorney Bellows believes that her exposure to the ABA Commission on Women in the Profession empowered her to pursue real change. She elaborates on her career path after Commission on Women including involvement in the Litigation Section.

Published
2012

30. Omar J. Alaniz: 2011 National Outstanding Young Lawyer.

Author

Johnson, Kara J.

Subjects
LAWYERS, ACADEMIC degrees, PRO bono publico legal services, LEGAL professionals' awards
Abstract

The article profiles Omar J. Alaniz, recipient of the American Bar Association Young Lawyers Division's (ABA YLD) National Outstanding Young Lawyer of 2011. He is a senior associate at Baker Botts LLP in Dallas, Texas and specializes in the area of Chapter 11 bankruptcy reorganizations and liquidations. He earned his Doctor of Law degree from the University of Texas School of Law. Also included are information on his pro bono work, other awards and personal life.

Published
2012

31. The North Dakota Young Lawyers Section Reaches Out to the Standing Rock Sioux Reservation Community.

Author

Johnson, Kara

Subjects
LAWYERS
Abstract

The article reports that North Dakota U.S. Attorney Tim Purdon reached out to lawyers across the state and asked them to make a positive impact on four reservations located within North Dakota. It is stated that North Dakota Young Lawyers Section (ND YLS) answered to Purdon's call and worked with Standing Rock Sioux Tribal Attorneys to organize outreach programs on Standing Rock Sioux Reservation. It is noted that ND YLS received subgrants from American Bar Association Young Lawyers Division.

Published
2013

32. Tips for Success: Working with Your Affiliates Staff.

Author

Johnson, Kara

Subjects
PUBLIC relations, LAWYERS, COMMUNICATION, ORGANIZATIONAL goals, LEGAL professions
Abstract

The article offers tips on how affiliate leaders can work best with their bar staff to achieve affiliate's goals. According to the article, the staff is a source of institutional knowledge and can be used as a public relations team and conduit of information to inform affiliates of trends. Key to ensuring a successful bar year is for affiliate leaders to have positive working relationship with the bar staff by using their time effectively without overburdening their capacity.

Published
2012

33. Omar J. Alaniz.

Author

Johnson, Kara J.

Subjects
LEGAL professions
Abstract

The article offers brief information on Omar J. Alaniz who become the American Bar Association Young Lawyers Division's National Outstanding Young Lawyer of 2011.

Published
2012

34. AROUND THE COUNTRY….

Subjects
BAR associations, JOB hunting, EMPLOYEE recruitment, LAWYERS
Abstract

The article presents updates on several American Bar Association Young Lawyers Division affiliates in the U.S. as of November 2010. The Minnesota State Bar Association New Lawyers Section plans to host a panel on obtaining jobs though alternative processes. More than 100 Omaha lawyers and judges attended the Steak Fry event of the Omaha Barristers on June 22.

Published
2010

35. SEEING THROUGH THE HAZE: NAVIGATING VETERAN EMPLOYMENT RIGHTS IN GOVERNMENT CONTRACTING, MEDICAL MARIJUANA, AND THE DRUG-FREE WORKPLACE ACT OF 1988.

Author

Hautanen, Anastasia

Subjects
Medical marijuana -- Laws, regulations and rules -- Usage, Veterans -- Care and treatment -- Employment -- Laws, regulations and rules, Government contractors -- Laws, regulations and rules -- Standards -- Usage, Government regulation, Controlled Substances Act of 1970, Vietnam Era Veterans' Readjustment Assistance Act of 1974, Drug-Free Workplace Act of 1988
Abstract

TABLE OF CONTENTS I. Introduction 372 II. The Current Legal Landscape of Medical Marijuana 376 A. Federal Laws 377 1. The Controlled Substances Act of 1970 377 2. The Drug [...]

Published
2020

36. Proteins and Nucleic Acids : The Biochemistry of Plants

Author

Abraham Marcus and Abraham Marcus

Subjects
Botanical chemistry
Abstract

The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information. This book presents the processes by which the nucleic acids are finally expressed as proteins. Organized into 14 chapters, this volume begins with an overview of the overall structure of eukaryotic genomes, with emphasis on higher-plant DNA. This text then examines the enzymes involved in the cleavage and degradation of DNA. Other chapters provide a critical assessment of eukaryotic nucleic acid polymerases. This book discusses as well some examples from plant mitochondrial systems. The final chapter deals with two special areas of plant biology where the expression of the nucleic acids is seen in striking relief, the formation of plant tumors, and the growth and expression of plant viruses. This book is a valuable resource for plant biochemists, molecular biologists, senior graduate students, and research workers.

Published
1981

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