392 results on '"F, Rozet"'
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2. Re: Effect of Prior Focal Therapy on Perioperative, Oncologic and Functional Outcomes of Salvage Robotic Assisted Radical Prostatectomy: I. Nunes-Silva, E. Barret, V. Srougi, M. Baghdadi, P. Capogrosso, S. Garcia-Barreras, S. Kanso, R. Tourinho-Barbosa, A. Carneiro, R. Sanchez-Salas, F. Rozet, M. Galiano and X. Cathelineau J Urol 2017;198:1069-1076.
- Author
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Shah TT, Valerio M, and Ahmed HU
- Subjects
- Humans, Male, Prostatectomy, Salvage Therapy, Prostatic Neoplasms surgery, Robotic Surgical Procedures
- Published
- 2018
- Full Text
- View/download PDF
3. Addendum concernant : « Étude prospective monocentrique comparant la prostatectomie totale rétropubienne à la laparoscopie robot-assistée : résultats carcinologiques et fonctionnels d’une série consécutive » écrit par J.B. Beauval et al. [Prog. Urol. 25 (2015) 370–8] et par F. Rozet [Prog. Urol. 25 (2015) 379–80]
- Author
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Barré, C., primary and Nguyen, J.-M., additional
- Published
- 2016
- Full Text
- View/download PDF
4. [Addendum concerning: 'A prospective trial comparing consecutive series of open retropubic and robot-assisted laparoscopic radical prostatectomy in a centre: Oncologic and functional outcomes' written by J.B. Beauval et al. [Prog. Urol. 25 (2015) 370-8] and F. Rozet [Prog. Urol. 25 (2015) 379-80]]
- Author
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C, Barré and J-M, Nguyen
- Subjects
Male ,Prostatectomy ,Treatment Outcome ,Humans ,Prostatic Neoplasms ,Laparoscopy ,Prospective Studies ,Robotics - Published
- 2015
5. Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
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T Richards, S Shaikh, S Rehman, A Khan, J Shah, C Smith, A Brown, S Singh, A P Arnaud, A Young, D Bowen, P Patel, S Williams, J Dunn, J John, M Loubani, A Hainsworth, A Kolias, PJ Hutchinson, R Singh, S Sinha, S Shaw, J Edwards, S Mukherjee, AAB Jamjoom, A Singh, S Saeed, J Martin, S Smith, S Ross, M Mohan, P Hutchinson, G James, RDC Moon, P Brennan, A Williams, S Brown, A Ward, M Lee, K Thompson, S Ali, J Williams, S Reid, U Khan, J Lambert, A Smith, B Singh, M Hassan, N Sharma, J Reynolds, N Wright, T Williams, H Smith, M Ng, M Rahman, A Taylor, P Shah, D Saxena, J Evans, I Omar, M Ali, A Hanson, Z Li, R Andrade, P Cardoso, H Jeong, P Sharma, M Arrieta, J Clark, L Pearce, J McVeigh, V Sharma, B Kim, J Singh, S Newman, J Byrne, A Hassan, A Persad, A Gardner, H Liu, K Shah, I Hughes, S Davison, A Balakrishnan, K Patel, J Hall, S Mistry, J Parry, R Baumber, N McGrath, E Ross, R Mannion, S Murphy, FL Wright, A Rogers, B Rai, M Thomas, R Ribeiro, E Hamilton, J Teixeira, B Davidson, L Carvalho, R Garrido, A Puppo, A Guimarães, E Santos, M Kamal, M Denning, M Elhadi, J E Fitzgerald, D Miller, M Gowda, C Morris, A Phillips, H Yang, Y Zhang, N Machairas, A Fisher, A Kaufmann, A Aggarwal, L Hansen, M Otify, H Soleymani Majd, A Jones, M Rodrigues, S Sundar, C Jones, R Edmondson, A Sharkey, L Smith, G Williams, J Dunning, E Belcher, D Stavroulias, V Zamvar, M Patel, M Baker, R Evans, M Sherif, J Hopkins, R Mohammed, A Hill, H Jackson, G Jones, K George, J Dixon, A Tong, S Jallad, Deborah S Keller, A Pereira, L Elliott, D Ford, A Sermon, M Almond, Andrew Metcalfe, C Peluso, T White, S Shah, A Witek, Chetan Khatri, A Tiwari, T Lo, K Agarwal, C Sweeney, C Hart, T Holme, S Green, I Ahmed, A Sobti, C Anderson, N Modi, R Campbell, C Magee, M Mirza, D Jones, N Stylianides, X Luo, C Kang, J Ribeiro, L Kumar, J Diaz, A Bhalla, R Young, C Perkins, A James, A Walters, J Reid, R Pereira, C McDonald, A Aujayeb, K Jackson, M Allen, D Ghosh, M Chan, C Price, K Khan, R Moore, M Ibrahim, A Marchbank, M Silva, M Baig, J De Coster, J Castellanos, S Saxena, M Duque, E Li, E Martin, A Isik, J González, RJ Davies, B Smith, R Owen, K Lakhoo, M Rogers, MA Akhtar, K Mellor, S Agrawal, L Foster, G Harris, J McIntyre, M Garner, R West, R Cuthbert, D Johnson, H Gomes, C Roy, N Spencer, D Mehta, J Freedman, J Blair, K Rajput, K Williams, J Wall, A Soliman, F Chen, A Mokhtari, I Mohamed, J Pascoe, M Khalifa, R Das, A Lara, M Costa, A Mahmoud, K Roberts, J Lane, S Robertson, J P Evans, E Krishnan, I Haq, S Rogers, J Knowles, M Chowdhury, A Ghanbari, L Macdonald, S Powell, J Hunt, J Cornish, J Engel, S Page, I Blake, A Rolls, H Ross, D Simpson, J Hammond, A Goyal, K Parkins, A Desai, A Gaunt, A Salim, Y Yousef, A Schache, H Mohan, SR Brown, R Nair, M Flatman, J Lord, RJ Egan, R Harries, N Judkins, K Sugand, T Hine, J Luck, C Johnson, G Salerno, AW Phillips, R Houston, A Volpe, C Walker, C Steele, M Rela, C Barry, R Alves, L Ramsay, A Turnbull, A Daniele, C S Jones, P Gallagher, G Gradinariu, A Oliveira, C Hardie, H Ferguson, S Bhattacharya, E Davies, P Joshi, C Mellor, E Griffiths, A Bhangu, R Mahoney, F Kashora, G Ruiz, K Wong, G Hill, V Testa, S Ford, C Park, P Gomez, C Lopes, A Lázaro, A Shabana, A Agarwal, C Chung, C Politis, G Martin, E Chung, M Ismail, C Cunha, S Correia, I Santos, A Tang, A Robson, T Collier, G Baltazar, M Quintana, C English, M Ip, K Newton, J Kahn, C Tan, D Cheng, R Woods, M Ho, A ABBAS, A Henry, F Rivas, M Mohammed, N Parsons, T Board, S Madan, A Osorio, M Jarvis, M Hashem, A Egglestone, E Halliday, A Ridgway, G Gallo, J Gilliland, W Marx, R Shaw, A Mahmood, K Gohil, B Gallagher, D Alderson, A Karim, G D Stewart, G Peck, L Majkowski, J Carter, H Ishii, L HUMPHREYS, J Khan, S Abbott, C Newton, F Borghi, A Sud, K Bhatia, H Cao, V Vijay, L Sanderson, E Holler, N Hanna, D Ferguson, P Miranda, L Pickering, T Singhal, T Newman, K Ghosh, C Camacho, D Manning, C Lipede, R Clifford, S Higgs, C Menakaya, S Shankar, K Booth, M Abdalla, T Nelson, T Farrell, H Naseem, J Johnstone, A Wilkins, A Brunt, A Nogués, A Patience, D Jeevan, M Vatish, G Stables, S Adegbola, I Hunt, K Dickson, W Matthews, N Dunne, M Maher, G Faulkner, E Hernandez, R Sofat, K Sahnan, A Brunelli, M Raza, K Chui, C Brennan, P Vaughan, H Chu, R Hagger, ASD Liyanage, R Perkins, S Duff, C Gill, H Dean, S Bandyopadhyay, K Ragupathy, Y Cunningham, A Bateman, V Brown, B Ho, E Britton, H Ikram, R Hasan, A Colquhoun, S Handa, A Maqsood, M Caputo, J Torkington, G Fusai, N Hossain, DJ Lin, S Stefan, IR Daniels, D Pournaras, A Askari, P Nisar, S Moug, J Sagar, N Yassin, G Minto, Z Hamady, JR O'Neill, S Chowdhury, R Cresner, D Vimalachandran, FD Mcdermott, RP Jones, P Zerbib, L Sreedharan, S Wahed, SS Gisbertz, MI van Berge Henegouwen, R Preece, I Liew, S McCluney, D Watts, D Nehra, B Dean, D Chaudhry, L Ross, F Solari, S Chatterji, B Barmayehvar, S Lourenco, L Onos, F Mansour, A Radhakrishnan, M Varcada, M Richmond, I Hernández, A Spinelli, H Pham, J Shalhoub, F Wells, K Bevan, A Peckham-Cooper, N Campain, J Steinke, R Wilkin, K McEvoy, S Mastoridis, N Fine, J Bayer, Y Joshi, A Yener, S C McKay, NS Kalson, S Horvath, H Fu, A Parente, SE Lewis, Y Ahmad, G Seidel, M Dunstan, U von Oppell, J Vatish, H Hirsch, K Breen, C Dott, D Mathieu, J Hardie, K Aldridge, A Doorgakant, P Petrone, R Tansey, M El Amrani, C Branco, Y Viswanath, A Meagher, B Keeler, N Tewari, A Gabr, J Kinross, M Longhi, E M Harrison, P Daliya, P Asaad, F Langlands, N Misra, S Kristinsson, S Di Saverio, C Conso, H Roy, E Massie, L Masterson, D Baskaran, A Hannah, O Ismail, S URBAN, J Domenech, S Ranjit, L Massey, S Mannan, D Rutherford, F Colombo, R Kulkarni, D Kearney, Neil J Smart, G Bourke, D Shrestha, P Nankivell, O Breik, R Exley, D Zakai, AK Abou-Foul, P Naredla, R Vidya, G Mundy, H Marin, A E Ward, A Sudarsanam, W Singleton, M Ganau, F Moura, J Blanco, R Myatt, S Sousa, H Zahid, S Garrido, A Fell, E Caruana, D Nepogodiev, F Dhaif, B Bankhad-Kendall, H Kaafarani, C Bretherton, L Marais, K Siaw-Acheampong, B E Dawson, J C Glasbey, R R Gujjuri, E Heritage, S K Kamarajah, J M Keatley, S Lawday, G Pellino, J F F Simoes, I M Trout, M L Venn, R J W Wilkin, A O Ademuyiwa, E Al Ameer, O Alser, K M Augestad, B Bankhead-Kendall, R A Benson, S Chakrabortee, R Blanco-Colino, A Brar, A Minaya Bravo, K A Breen, I Lima Buarque, M F Cunha, G H Davidson, S Farik, M Fiore, G M A Gomes, C Halkias, I Lawani, H Lederhuber, S Leventoglu, M W Loffler, H Mashbari, D Mazingi, D Moszkowicz, J S Ng-Kamstra, S Metallidis, M Niquen, F Ntirenganya, O Outani, F Pata, T D Pinkney, P Pockney, D Radenkovic, A Ramos-De la Medina, A Schnitzbauer, S Shu, K Soreide, S Tabiri, P Townend, G Tsoulfas, G van Ramshorst, Mak JKC, F Tirotta, A Kisiel, LD Cato, AM Pathanki, A Chebaro, K Lecolle, S Truant, FR Pruvot, E Surmei, L Mattei, J Dudek, S El-Hasani, J Cuschieri, GH Davidson, RG Wade, H Elkadi, C Pompili, JR Burke, E Bagouri, Z Abual-Rub, S Munot, M Kowal, SC Winter, F Di Chiara, K Wallwork, A Qureishi, M Lami, S Sravanam, S Chidambaram, R Smillie, AV Shaw, C Cernei, D Jeyaretna, RJ Piper, E Duck, C Jelley, SC Tucker, G Bond-Smith, XL Griffin, GD Tebala, N Neal, TM Noton, H Ghattaura, OBF Risk, H Kharkar, C Verberne, A Senent-Boza, A Sánchez-Arteaga, I Benítez-Linero, F Manresa-Manresa, L Tallón-Aguilar, L Melero-Cortés, MR Fernández-Marín, VM Durán-Muñoz-Cruzado, I Ramallo-Solís, P Beltrán-Miranda, F Pareja-Ciuró, BT Antón-Eguía, AC Dawson, A Drane, F Oliva Mompean, J Gomez-Rosado, J Reguera-Rosal, J Valdes-Hernandez, L Capitan-Morales, del Toro Lopez, A Alanbuki, O Usman, AJ Beamish, D Bosanquet, D Magowan, H Nassa, G Mccabe, D Holroyd, NB Jamieson, NM Mariani, V Nicastro, D Motter, C Jenvey, T Minto, DR Sarma, C Godbole, W Carlos, A Khajuria, H Connolly, G Di Taranto, S Shanbhag, J Skillman, M Sait, H Al-omishy, B Heer, R Lunevicius, ARG Sheel, M Sundhu, AJA Santini, Fathelbab MSAT, KMA Hussein, QM Nunes, K Shahzad, Baig MMAS, JL Hughes, A Kattakayam, SB Shah, AL Clynch, N Georgopoulou, HM Sharples, AA Apampa, IC Nzenwa, D Podolsky, NL Coleman, MP Callahan, P Beak, I Gerogiannis, A Ebrahim, A Alwadiya, C Demetriou, E Grimley, E Theophilidou, E Ogden, FL Malcolm, G Davies-Jones, Ng JCK, N Elmaleh, Z Chia, J A'Court, A Konarski, R Talwar, P S Jambulingam, A Maity, C Hatzantonis, S Kudchadkar, N Cirocchi, CH Chan, H Eberbach, B Erdle, R Sandkamp, G Velmahos, LR Maurer, M El Moheb, A Gaitanidis, L Naar, MA Christensen, C Kapoen, K Langeveld, M El Hechi, B Main, T Maccabe, NS Blencowe, DP Fudulu, D Bhojwani, M Baquedano, F Rapetto, O Flannery, D Tadross, C Blundell, S Forlani, S Guha, CJ Kelty, G Chetty, G Lye, SP Balasubramanian, N Sureshkumar Shah, A Al-mukhtar, E Whitehall, A Giblin, A Adamec, J Konsten, M Van Heinsbergen, A Sou, J Jimeno Fraile, D Morales-Garcia, M Carrillo-Rivas, E Toledo Martínez, Pascual À, A Landaluce-olavarria, M Gonzalez De miguel, Fernández Gómez Cruzado L, E Begoña, D Lecumberri, A Calvo Rey, GM Prada hervella, L Dos Santos Carregal, MI Rodriguez Fernandez, M Freijeiro, S El Drubi Vega, J Van den Eynde, W Oosterlinck, R Van den Eynde, A Boeckxstaens, A Cordonnier, J Jaekers, M Miserez, M Galipienso Eri, JD Garcia Montesino, J Dellonder Frigolé, D Noriego Muñoz, V Lizzi, F Vovola, A Arminio, A Cotoia, AL Sarni, M Bekheit, BS Kamera, M Elhusseini, A Ahmeidat, W Cymes, G Mignot, J Agilinko, A Sgrò, MM Rashid, K Milne, KE Stewart, MSJ Wilson, K McGivern, BC Brown, B Wadham, IA Aneke, J Collis, H Warburton, DM Fountain, R Laurente, KV Sigamoney, M Dasa, Z Naqui, M Galhoum, MT Hasan, R Kalenderov, O Pathmanaban, R Chelva, K Subba, M Khalefa, F Hossain, T Moores, J Anthoney, O Emmerson, R Makin-Taylor, CS Ong, R Callan, O Bloom, G Chauhan, J Kaur, A Burahee, S Bleibleh, N Pigadas, D Snee, S Bhasin, A Crichton, A Habeebullah, AS Bodla, M Mondragon, V Dewan, MC Giuffrida, A Marano, S Palagi, S Di Maria Grimaldi, A Simonato, M D'Agruma, R Chiarpenello, L Pellegrino, F Maione, D Cianflocca, Pruiti Ciarello, G Giraudo, E Gelarda, E Dalmasso, A Abrate, V Ciriello, F Rosato, A Garnero, L Leotta, M Chiozza, G Anania, A Urbani, M Koleva Radica, P Carcoforo, M Portinari, M Sibilla, JE Archer, A Odeh, N Siddaiah, H Carmichael, CG Velopulos, RC McIntyre, TJ Schroeppel, EA Hennessy, L Zier, C Parmar, JM Muñoz Vives, CJ Gómez Díaz, CA Guariglia, C Soto Montesinos, L Sanchon, M Xicola Martínez, N Guàrdia, P Collera, R Diaz Del Gobbo, R Sanchez Jimenez, R Farre Font, R Flores Clotet, CEM Brathwaite, H Hakmi, AH Sohail, R Heckburn, D Townshend, N McLarty, A Shenfine, K Madhvani, M Hampton, AP Hormis, V Miu, K Sheridan, C Luney, MA Williams, A Alqallaf, A Ben-Sassi, R Crichton, J Sonksen, GR Layton, B Karki, S Pankhania, S Asher, A Folorunso, J Winyard, J Mangwani, BHB Babu, C Weerasinghe, M Ballabio, P Bisagni, T Armao, M Madonini, A Gagliano, P Pizzini, A Älgå, M Nordberg, G Sandblom, J El Kafsi, K Logishetty, A Saadya, R Midha, H Subbiah Ponniah, T Stockdale, T Bacarese-Hamilton, N Anjarwalla, D Marujo Henriques, R Hettige, C Baban, A Tenovici, F Anazor, SD King, S Kazzaz, S HKruijff, De Vries JPPM, PJ Steinkamp, PKC Jonker, WY Van der Plas, W Bierman, Y Janssen, ABJ Borgstein, D Enjuto, M Perez Gonzalez, P Díaz Peña, M Marqueta De Salas, P Martinez Pascual, L Rodríguez Gómez, R Garcés García, A Ramos Bonilla, N Herrera-Merino, P Fernández Bernabé, EP Cagigal Ortega, García de Castro Rubio E, I Cervera, MH Siddique, C Barmpagianni, A Basgaran, A Basha, V Okechukwu, A Bartsch, CA Leo, HK Ubhi, N Zafar, H Abdul-Jabar, F Mongelli, M Bernasconi, M Di Giuseppe, D Christoforidis, D La Regina, M Arigoni, A Al-Sukaini, S Mediratta, O Brown, M Boal, S Stanger, H Abdalaziz, J Constable, G Dovell, R Gopi reddy, A Dehal, HB Shah, GWV Cross, P Seyed-Safi, YW Smart, A Kuc, M Al-Yaseen, B Jayasankar, D Balasubramaniam, K Abdelsaid, N Mundkur, RE Soulsby, O Ryska, T Raymond, P Hawkin, G Kinnaman, I Sharma, K Freystaetter, JN Hadfield, A Hilley, S Arkani, M Youssef, I Shaikh, K Seebah, V Kouritas, D Chrastek, G Maryan, DF Gill, F Khatun, J Parakh, V Sarodaya, A Daadipour, KD Bosch, V Bashkirova, LS Dvorkin, VK Kalidindi, A Choudhry, M Espino Segura-Illa, G Sánchez Aniceto, AM Castaño-Leon, L Jimenez-Roldan, J Delgado Fernandez, A Pérez Núñez, A Lagares, D Garcia Perez, M Santas, I Paredes, O Esteban Sinovas, L Moreno-Gomez, E Rubio, V Vega, A Vivas Lopez, M Labalde Martinez, O García Villar, PM Pelaéz Torres, J Garcia Borda, E Ferrero Herrero, C Eiriz Fernandez, C Ojeda-Thies, JM Pardo Garcia, H Wynn Jones, H Divecha, C Whelton, E Powell-Smith, M Alotaibi, A Maashi, A Zowgar, M Alsakkaf, O Izquierdo, D Ventura, D Escobar, U Garcia de cortazar, Villamor Garcia, A Cioci, K Rakoczy, W Pavlis, R Saberi, A Khaleel, A Unnithan, K Memon, RR Pala Bhaskar, F Maqboul, F Kamel, A Al-Samaraee, R Madani, H Llaquet Bayo, N Duchateau, C De Gheldere, A Fayad, ML Wood, G Groot, I Hakami, C Boeker, J Mall, AF Haugstvedt, ML Jönsson, P Caja Vivancos, Villalabeitia Ateca, M Prieto Calvo, P Martin Playa, A Gainza, EJ Aragon Achig, A Rodriguez Fraga, Melchor Corcóstegui, G Mallabiabarrena Ormaechea, JJ Garcia Gutierrez, L Barbier, MA Pesántez Peralta, M Jiménez Jiménez, JA Municio Martín, J Gómez Suárez, G García Operé, LA Pascua Gómez, M Oñate Aguirre, A Fernandez-Colorado, M De la Rosa-Estadella, A Gasulla-Rodriguez, M Serrano-Martin, A Peig-Font, S Junca-Marti, M Juarez-Pomes, S Garrido-Ondono, L Blasco-Torres, M Molina-Corbacho, Y Maldonado-Sotoca, A Gasset-Teixidor, J Blasco-Moreu, V Turrado-Rodriguez, AM Lacy, FB de Lacy, X Morales, A Carreras-Castañer, P Torner, M Jornet-Gibert, M Balaguer-Castro, M Renau-Cerrillo, P Camacho-Carrasco, M Vives-Barquiel, B Campuzano-Bitterling, I Gracia, R Pujol-Muncunill, M Estaire Gómez, D Padilla-Valverde, S Sánchez-García, D Sanchez-Pelaez, E Jimenez Higuera, R Picón Rodríguez, Fernández Camuñas À, C Martínez-Pinedo, EP Garcia Santos, V Muñoz-Atienza, A Moreno Pérez, CA Cano, D Crego-Vita, M Huecas-Martinez, A Roselló Añón, MJ Sangüesa, JC Bernal-Sprekelsen, JC Catalá Bauset, P Renovell Ferrer, C Martínez Pérez, O Gil-Albarova, J Gilabert Estellés, K Aghababyan, R Rivas, J Escartin, JL Blas Laina, B Cros, Talal El-Abur, J Garcia Egea, C Yanez, JH Kauppila, E Sarjanoja, S Tzedakis, PA Bouche, S Gaujoux, D Gossot, A Seguin-Givelet, D Fuks, M Grigoroiu, R Sanchez Salas, X Cathelineau, P Macek, Y Barbé, F Rozet, E Barret, A Mombet, N Cathala, E Brian, F Zadegan, AJ Baldwin, E Gammeri, A Catton, S Marinos Kouris, J Pereca, M Kaushal, A Kler, V Reghuram, S Tezas, V Oktseloglou, F Mosley, MFI De La Cruz Monroy, P Bobak, S Ahad, E Lostis, GK Ambler, J Manara, M Doe, T Jichi, GD Stewart, J Ramzi, AA Singh, J Ashcroft, OJ Baker, P Coughlin, Durst AZED, A Abood, A Habeeb, VE Hudson, B Lamb, L Luke, S Mitrasinovic, Ngu AWT, S Waseem, F Georgiades, XS Tan, J Pushpa-rajah, I Abu-Nayla, S Rooney, E Irune, MHV Byrne, A Durrani, A Sethuraman Venkatesan, T Combellack, G Tahhan, M Kornaszewska, V Valtzoglou, I Deglurkar, M Koutentakis, Syed Nong Chek SAH, M Shinkwin, F Ayeni, H Tustin, M Bordenave, N Manu, N Eardley, OL Serevina, S Roy Mahapatra, K Mohankumar, I Khawaja, A Palepa, T Doulias, Y Premakumar, Y Jauhari, Z Koshnow, A Uberai, F Hirri, BM Stubbs, J Manickavasagam, S Dalgleish, R Kanitkar, CJ Payne, Ng CE, DE Henshall, T Drake, EM Harrison, A Tambyraja, RJE Skipworth, G Linder, R McGregor, J Mayes, R Pasricha, A Razik, S Thrumurthy, D Howden, Z Baxter, L Osagie, M Bence, GE Fowler, N Rajaretnam, A Goubran, JS McGrath, JRA Phillips, DA Raptis, JM Pollok, F Soggiu, S Xyda, C Hidalgo Salinas, H Tzerbinis, T Pissanou, R Mirnezami, N Angamuthu, T Shakir, H Capitelli-McMahon, L Hitchman, A Andronic, A Aboelkassem Ibrahim, J Totty, S Tayeh, T Chase, J Ayorinde, T Cuming, A Trompeter, C Hing, P Tsinaslanidis, MW Benjamin, A Leyte, J Smelt, G Santhirakumaran, A Labib, O Lyons, S Onida, KM Sarraf, S Erridge, S Yalamanchili, A Abuown, D Davenport, S Wheatstone, SM Andreani, MF Bath, A Sahni, L Rigueros Springford, C Sohrabi, J Bacarese-Hamilton, FG Taylor, P Patki, C Tanabalan, ME Alexander, CJ Smart, L Abdeh, M Zeiton, R Advani, S Nikolaou, T Oni, N Ilahi, K Ballantyne, Z Woodward, R Merh, B Robertson-Smith, P Ameerally, JG Finch, C Gnanachandran, I Pop, D Dass, G Thiruchandran, Toh SKC, A Allana, C Bellis, O Babawale, YC Phan, U Lokman, T Koc, L Duggleby, S Shamoon, H Clancy, A Mansuri, A Thakrar, L Wickramarachchi, S Sivayoganathan, E Karam, HV Colvin, A Badran, A Cadersa, A Cumpstey, R Aftab, F Wensley, V Morrison-Jones, GK Sekhon, H Shields, Z Shakoor, T Talbot, A Alzetani, J Rooney, M Rudic, A Aladeojebi, M Kitchen, R Lefroy, P Nanjaiah, AD Rajgor, RJ Scurrah, LJ Watson, T Royle, B Steel, Luk ACO, VG Thiruvasagam, W Marlow, C Konstantinou, D Yershov, A Denning, E Mangos, T Nambirajan, I Flindall, V Mahendran, J De Marchi, NF Davis, A Picciariello, V Papagni, DF Altomare, S Granieri, C Cotsoglou, A Cabeleira, P Serralheiro, T Teles, C Canhoto, J Simões, AC Almeida, O Nogueira, R Athayde Nemésio, MJ Amaral, A Valente da Costa, R Martins, P Guerreiro, A Ruivo, D Breda, JM Oliveira, AL De Oliveira Lopez, M Colino, J De Barros, AP Soares, H Morais, T Revez, MI Manso, JC Domingues, P Henriques, Cardoso N Ribeiro VI, G Martins dos Santos, M Peralta Ferreira, J Ascensão, B Costeira, L Rio Rodrigues, M Sousa Fernandes, P Azevedo, I Lourenço, G Mendinhos, A Nobre Pinto, H Taflin, H Abdou, L O'Meara, Z Cooper, SA Hirji, BU Okafor, V Roxo, CP Raut, JS Jolissaint, DA Mahvi, C Reinke, S Merola, A Ssentongo, P Ssentongo, Oh JS, J Hazelton, J Maines, N Gusani, RCG Martin, N Bhutiani, R Choron, F Soliman, MD E Dauer, E Renza-Stingone, E Gokcen, E Kropf, H Sufrin, J Sewards, J Poggio, K Sanserino, L Rae, M Philp, M Metro, P McNelis, R Petrov, T Pazionis, DB Lumenta, SP Nischwitz, E Richtig, M Pau, P Srekl-Filzmaier, N Eibinger, B Michelitsch, M Fediuk, A Papinutti, TU Cohnert, E Kantor, J Kahiu, S Hosny, A Sultana, M Taggarsi, L Vitone, OP Vaz, I Sarantitis, S Timbrell, A Shugaba, GP Jones, SS Tripathi, MS Greenhalgh, H Emerson, K Vejsbjerg, W McCormick, K Singisetti, Y Aawsaj, R Vanker, M Ghobrial, S Kanthasamy, H Fawi, M Awadallah, J Cheung, S Tingle, F Abbadessa, A Sachdeva, CD Chan, I McPherson, F Mahmoud Ali, S Pandanaboyana, T Grainger, S Nandhra, N Dawe, C McCaffer, J Riches, J Moir, H Elamin Ahmed, C Saleh, RM Koshy, LJ Rogers, PL Labib, N Hope, K Emslie, P Panahi, E Clough, I Enemosah, J Natale, N Raza, JI Webb, M Antar, J Noel, R Nunn, F Eriberto, R Tanna, S Lodhia, C Osório, J Antunes, P Balau, and M Godinho
- Subjects
Medicine - Abstract
Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.Setting Prospective, international, multicentre, observational cohort study.Participants Patients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome 30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.Results This study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).Conclusions Patients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration number NCT04323644
- Published
- 2021
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6. Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study
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Minicozzi, L, Navaratne, P, Patki, R, Rahman, R, Ramamoorthy, C, Sohrabi, C, Tanabalan, M, Thaha, B, Thakur, M, Venn, V, Yip, R, Baumber, J, Parry, S, Evans, L, Jeys, G, Morris, M, Parry, N, Ahmadi, G, Aresu, Barrett-Brown, Z.M., A, Coonar, Yates H, Durio, D, Gearon, J, Hogan, M, King, A, Peryt, IS, Pradeep, M, Adishesh, R, Atherton, K, Baxter, M, Brocklehurst, M, Chaudhury, N, Krishnamohan, J, McAleer, G, Owens, E, Parkin, P, Patkar, I, Phang, A, Aladeojebi, M, Ali, B, Barmayehvar, A, Gaunt, M, Gowda, E, Halliday, M, Kitchen, F, Mansour, P, Nanjaiah, D, Zakai, Abbassi-Ghadi, N., H, Assalaarachchi, A, Currie, M, Flavin, A, Frampton, M, Hague, C, Hammer, J, Hopper, J, Horsnell, S, Humphries, A, Kamocka, TK, Madhuri, S, Preston, P, Singh, J, Stebbing, A, Tailor, D, Walker, E, Coomber, S, Jaunoo, L, Kennedy, A, Airey, J, Bunni, R, Crowley, K, Fairhurst, J, Frost, R, George, S, Lee, S, Mitchell, J, Phull, S, Richards, F, Aljanadi, A, Campbell, A, Glass, I, Hraishawi, M, Jones, C, McIlmunn, S, McIntosh, P, Mhandu, C, O’Donnell, R, Turkington, Al-Ishaq, Z., S, Bhasin, AS, Bodla, A, Burahee, A, Crichton, El-Ghobashy, A., R, Fossett, N, Pigadas, E, Rahman, D, Snee, R, Vidya, N, Yassin, D, Fountain, Hasan, M.T., K, Karabatsou, R, Laurente, O, Pathmanaban, C, Barlow, D, Ding, J, Foster, L, Longstaff, Brett-Miller, C., FE, Buruiana, A, Al-mukhtar, J, Edwards, A, Giblin, C, Kelty, M, Lee, G, Lye, T, Newman, A, Sharkey, C, Steele, Shah N, Sureshkumar, E, Whitehall, J, Blair, A, Lakhiani, Parry-Smith, W., B, Sahu, R, Athwal, A, Baker, L, Jones, C, Konstantinou, S, Ramcharan, J, Vatish, R, Wilkin, A, Alzetani, K, Amer, A, Badran, HV, Colvin, M, Ethunandan, GK, Sekhon, Z, Shakoor, H, Shields, R, Singh, T, Talbot, F, Wensley, S, Lawday, A, Lyons, S, Newman, E, Chung, R, Hagger, A, Hainsworth, I, Hunt, A, Karim, H, Owen, A, Ramwell, G, Santhirakumaran, J, Smelt, C, Tan, P, Vaughan, K, Williams, C, Baker, A, Davies, J, Gossage, M, Kelly, W, Knight, S, Bromage, J, Hall, V, Kaushik, M, Rudic, N, Vallabh, Y, Zhang, G, Harris, G, James, C, Kang, DJ, Lin, AD, Rajgor, T, Royle, R, Scurrah, B, Steel, LJ, Watson, D, Choi, R, Hutchison, V, Luoma, HJ, Marcus, R, May, A, Menon, B, Pramodana, L, Webber, A, Hayes, R, Jones, G, Sivarajah, M, Smith, A, Smrke, D, Strauss, FAM, Abouelela, IA, Aneke, P, Asaad, B, Brown, J, Collis, S, Duff, A, Khan, F, Moura, M, Taylor, B, Wadham, H, Warburton, T, Elmoslemany, Jenkinson, M.D., CP, Millward, R, Zakaria, S, Mccluney, C, Parmar, S, Shah, J, Allison, Babar, M.S., J, Bowen, B, Collard, S, Goodrum, K, Lau, M, Sargent, R, Scott, E, Thomas, H, Whitmore, D, Balasubramaniam, B, Jayasankar, S, Kapoor, A, Ramachandran, C, Semple, A, Elhamshary, SMB, Imam, K, Kapriniotis, V, Kasivisvanathan, J, Lindsay, Rakhshani-Moghadam, S., N, Beech, M, Chand, L, Green, N, Kalavrezos, H, Kiconco, R, McEwen, C, Schilling, D, Sinha, J, Pereca, S, Chopra, D, Egbeare, R, Thomas, S, Arumugam, B, Ibrahim, K, Khan, T, Combellack, G, Hill, S, Jones, M, Kornaszewska, M, Mohammed, G, Tahhan, V, Valtzoglou, N, Blencowe, P, Eskander, K, Gash, L, Gourbault, M, Hanna, TA, Maccabe, B, Main, J, Olivier, C, Newton, S, Roswadowski, N, Ryan, E, Teh, D, West, H, Al-omishy, M, Baig, H, Bates, Taranto G, Di, K, Dickson, N, Dunne, C, Gill, D, Howe, D, Jeevan, A, Khajuria, Martin-Ucar, A., K, McEvoy, P, Naredla, S, Robertson, M, Sait, DR, Sarma, S, Shanbhag, T, Shortland, S, Simmonds, J, Skillman, N, Tewari, G, Walton, Akhtar, M.A., A, Brunt, J, McIntyre, K, Milne, MM, Rashid, A, Sgrò, KE, Stewart, A, Turnbull, Abou-Foul, A.K., G, Gossedge, S, O’Donnell, F, Oldfield, S, Thomson, Gonzalez M, Aguilar, S, Talukder, C, Boyle, D, Fernando, K, Gallagher, A, Laird, D, Tham, M, Bath, P, Basnyat, H, Davis, P, Montauban, A, Shrestha, K, Agarwal, T, Arif, C, Magee, T, Nambirajan, S, Powell, R, Vinayagam, I, Flindall, A, Hanson, V, Mahendran, S, Green, M, Lim, L, MacDonald, V, Miu, L, Onos, K, Sheridan, R, Young, F, Alam, O, Griffiths, C, Houlden, VS, Kolli, AK, Lala, S, Leeson, R, Peevor, Z, Seymour, E, Consorti, R, Gonzalez, R, Grolman, Kwan-Feinberg, R., T, Liu, O, Merzlikin, Francisco, San, A, Brown, Z, Cooper, S, Hirji, J, Jolissaint, D, Mahvi, B, Okafor, CP, Raut, V, Roxo, A, Salim, S, Bessen, L, Chen, L, Dagrosa, K, Fay, C, Fleischer, R, Hasson, E, Henderson, M, Leech, A, Loehrer, C, Markey, J, Paydarfar, K, Rosenkranz, K, Telma, N, Tocci, Wilkinson-Ryan, I., M, Bokenkamp, K, Brown, D, Fleming, C, Heron, C, Hill, H, Kay, E, Leede, K, McElhinney, KA, Olson, EC, Osterberg, C, Riley, P, Srikanth, J, Barbour, D, Blazer, GA, DiLalla, O, Fayanju, ES, Hwang, R, Kahmke, H, Kazaure, A, Lazarides, W, Lee, M, Lidsky, C, Menendez, D, Moris, J, Plichta, MC, Pradhan, L, Puscas, HE, Rice, D, Rocke, L, Rosenberger, R, Scheri, Smith, B.D., Stang, M.T., L, Tolnitch, K, Turnage, J, Visgauss, FS, Walton, T, Watts, S, Zani, J, Farma, K, Cardona, MC, Russell, J, Clark, D, Kwon, N, Goel, J, Kronenfeld, B, Bigelow, E, Etchill, Gabre-Kidan, A., H, Jenny, A, Kent, MR, Ladd, C, Long, H, Malapati, A, Margalit, S, Rapaport, J, Rose, K, Stevens, L, Tsai, D, Vervoort, P, Yesantharao, A, Dehal, D, Klaristenfeld, K, Huynh, H, Kaafarani, L, Naar, M, Qadan, L, Brown, I, Ganly, JE, Mullinax, N, Alpert, C, Gillezeau, Miles DDS MD, F.A.C.S.B.A., E, Taioli, DE, Cha, E, Gleeson, C, Horn, U, Sarpel, N, Gusani, J, Hazelton, J, Maines, JS, Oh, A, Ssentongo, P, Ssentongo, A, Bhama, K, Colling, M, Najarian, M, Azam, A, Choudhry, W, Marx, Y, Abedin, G, Arzumanov, R, Chokshi, S, Gabrilovich, N, Glass, E, Kalyoussef, Parvin-Nejad, F.P., D, Roden, J, Stein, Suarez-Ligon, A., G, Tsui, K, Zhao, J, Fleming, A, Fuson, J, Gigliotti, A, Ovaitt, Y, Ying, MK, Abel, V, Andaya, K, Bigay, Boeck, M.A., H, Chern, C, Corvera, El-Sayed, I., A, Glencer, P, Ha, Hamilton, B.C.S., C, Heaton, K, Hirose, Jablons, D.M., KS, Kirkwood, LZ, Kornblith, JR, Kratz, RH, Lee, PN, Miller, EK, Nakakura, Nunez-Garcia, B., RJ, O’Donnell, D, Ozgediz, P, Park, B, Robinson, A, Sarin, B, Sheu, MG, Varma, KC, Wai, R, Wustrack, MJ, Xu, M, Zimel, D, CA) Beswick, J, Goddard, J, Manor, J, Song, Springs/Loveland, Denver/Colorado, A, Cioci, W, Pavlis, K, Rakoczy, G, Ruiz, R, Saberi, T, Fullmer, C, Gaskill, N, Gross, K, Kiong, CL, Roland, SN, Zafar, M, Abdallah, A, Abouassi, E, Aigbivbalu, M, Almasri, J, Eid, B, George, G, Kulkarni, H, Marwan, M, Mehdi, Andrés M, San, J, Sundaresan, SG, Aoun, VS, Ban, HH, Batjer, K, Bosler, J, Caruso, B, Sumer, D, Abbott, A, Acher, T, Aiken, J, Barrett, E, Foley, PB, Schwartz, AT, Hawkins, A, Maiga, NM, Ruzgar, M, Sion, S, Ullrich, J, Laufer, S, Scasso, Al-Naggar, H., Al-Shehari, M., A, Almassaudi, M, Alsayadi, R, Alsayadi, M, Nahshal, S, Shream, S, AL-Ameri, M, Aldawbali, Fotopoulou, Christina, Khan, Tabassum, Bracinik, Juraj, Glasbey, James, Abu-Rustum, Nadeem, Chiva, Luis, Fagotti, Anna, Fujiwara, Keiichi, Ghebre, Rahel, Gutelkin, Murat, Konney, Thomas O., Ng, Joseph, Pareja, Rene, Kottayasamy Seenivasagam, Rajkumar, Sehouli, Jalid, Surappa, Shylasree T.S., and Leung, Elaine
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- 2022
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7. Focal brachytherapy for localized prostate cancer: Mid-term outcomes
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I. Nunes-Silva, M-H. Ta, E. Barret, F. Rozet, P. Macek, A. Mombet, R. Sanchez-Salas, N. Cathala, X. Cathelineau, and J-M. Cosset
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Diseases of the genitourinary system. Urology ,RC870-923 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2020
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8. Técnicas, indicaciones y resultados del vaciamiento ganglionar por vía laparoscópica robótica en el tratamiento del cáncer de próstata
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C. Laine, F. Rozet, and X. Cathelineau
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General Medicine - Published
- 2022
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9. New prostate-specific antigen study findings recently were published by F. Rozet and co-researchers
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Analysis ,Research ,Reports ,Antigens -- Reports -- Analysis -- Research ,Body mass index -- Reports -- Analysis -- Research ,Prostate cancer -- Research -- Reports -- Analysis - Abstract
Researchers detail in 'A direct comparison of robotic assisted versus pure laparoscopic radical prostatectomy: a single institution experience,' new data in prostate-specific antigen. According to a study from Paris, France, [...]
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- 2007
10. Mid-term oncologic outcomes of radical prostatectomy in lymph node metastatic prostate cancer patients
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W. Berchiche, T. Long Depaquit, M. Baboudjian, É. Barret, F. Rozet, X. Cathelineau, and C. Bastide
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Urology - Published
- 2023
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11. French AFU Cancer Committee Guidelines - Update 2022-2024: prostate cancer - Management of metastatic disease and castration resistance
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G. Ploussard, G. Roubaud, E. Barret, J.-B. Beauval, L. Brureau, G. Créhange, C. Dariane, G. Fiard, G. Fromont, M. Gauthé, R. Renard-Penna, F. Rozet, A. Ruffion, P. Sargos, R. Mathieu, M. Rouprêt, Clinique La Croix du Sud, Institut Bergonié [Bordeaux], UNICANCER, Institut Mutualiste de Montsouris (IMM), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École des Hautes Études en Santé Publique [EHESP] (EHESP), Institut Curie [Paris], National Cystic Fibrosis Reference Center [CHU Necker] (CNR - INSERM U1151), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Centre pour l'innovation en cancérologie de Lyon (CICLY), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, and CHU Pontchaillou [Rennes]
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Treatment ,Prostate cancer ,Urology ,Recommandations ,[SDV]Life Sciences [q-bio] ,Diagnosis ,Diagnostic ,Cancer de la prostate ,Guidelines ,Traitement - Abstract
International audience; OBJECTIVE: The objective of the French Urology Association Cancer Committee is to propose an update of the recommendations for the management of prostate cancer. METHODS: A systematic review of the literature from 2020 to 2022 was conducted by the CCAFU on the elements of therapeutic management of metastatic and castration-resistant prostate cancer (PC), while evaluating the references and their levels of evidence. RESULTS: Androgen deprivation therapy (ADT) remains the standard treatment for metastatic prostate cancer. ADT intensification is now a standard of care in the management of metastatic prostate cancer. This intensification is discussed in relation to the patient and the characteristics of the disease. For all metastatic hormone-sensitive PC (synchronous and metachronous), the overall survival benefit associated with good tolerability makes the combination of ADT and novel hormonal agents (NHA) a standard. For patients with high-volume/high-risk de novo metastatic disease, treatment with docetaxel in addition to ADT + NHA can be discussed for eligible patients. In patients with castration-resistant prostate cancer (CRPC), the contribution of new therapies that have become available in recent years, as well as the advent of precision medicine, help to improve the control of tumour progression and survival, and highlight the value of testing for alterations in DNA repair genes within the tumour tissue or constitutionally. CONCLUSION: This update of the French recommendations should help to improve the management of patients with prostate cancer.
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- 2022
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12. French AFU Cancer Committee Guidelines - Update 2022-2024: prostate cancer - Diagnosis and management of localised disease
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G. Ploussard, G. Fiard, E. Barret, L. Brureau, G. Créhange, C. Dariane, G. Fromont, M. Gauthé, R. Mathieu, R. Renard-Penna, G. Roubaud, F. Rozet, A. Ruffion, P. Sargos, J.-B. Beauval, M. Rouprêt, Clinique La Croix du Sud, Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Université Grenoble Alpes - UFR Médecine (UGA UFRM), Institut Mutualiste de Montsouris (IMM), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École des Hautes Études en Santé Publique [EHESP] (EHESP), Institut Curie [Paris], National Cystic Fibrosis Reference Center [CHU Necker] (CNR - INSERM U1151), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Pontchaillou [Rennes], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Bergonié [Bordeaux], UNICANCER, Centre pour l'innovation en cancérologie de Lyon (CICLY), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), and Hospices Civils de Lyon (HCL)
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Treatment ,Prostate cancer ,Urology ,Recommandations ,[SDV]Life Sciences [q-bio] ,Diagnosis ,Diagnostic ,Cancer de la prostate ,Guidelines ,Traitement - Abstract
International audience; OBJECTIVE: The objective of the French Urology Association Cancer Committee is to propose an update of the recommendations for the diagnosis and management of prostate cancer (PC). METHODS: A systematic review of the literature from 2020 to 2022 was conducted by the CCAFU on the diagnosis and therapeutic management of localised PC, while evaluating the references and their levels of evidence. RESULTS: The recommendations specify the genetics, epidemiology and means of diagnosing prostate cancer, as well as the notions of screening and early detection. MRI, the gold standard imaging examination for localised cancer, is recommended before prostate biopsies are performed. The transperineal approach reduces the risks of infection. The therapeutic methods are described and recommended according to the clinical context. Active surveillance is the gold standard of treatment for tumours with a low risk for progression. Early salvage radiotherapy is recommended in case of biochemical recurrence after radical prostatectomy. Imaging, particularly molecular imaging, helps to guide the decision-making in the event of biochemical recurrence after local treatment, but should not delay early salvage radiotherapy in the event of biological recurrence after radical prostatectomy. CONCLUSION: This update of the French recommendations should help to improve the management of patients with PC.
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- 2022
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13. Vigilancia activa del cáncer de próstata
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Guillaume Ploussard, Pierre Mongiat-Artus, and F. Rozet
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General Medicine - Abstract
Resumen El aumento de la incidencia del cancer de prostata (CaP) en los ultimos anos se ha producido principalmente a expensas de los CaP de bajo riesgo evolutivo. El concepto de vigilancia activa de estos CaP con bajo riesgo de progresion surgio paulatinamente al mismo tiempo que el concepto de sobretratamiento. La vigilancia activa es un tratamiento curativo destinado a preservar la calidad de vida del paciente, remitiendo el tratamiento radical a una posible progresion, sin perder las posibilidades de curacion. La vigilancia activa se basa en un estricto protocolo de seguimiento del paciente, que permite detectar a tiempo una posible progresion de la enfermedad hacia un estadio desfavorable, posibilitando la propuesta de un tratamiento activo diferido, sin riesgo oncologico para el paciente. Actualmente, se dispone de los resultados oncologicos a largo plazo de la vigilancia activa gracias a grandes series prospectivas. Estos resultados han confirmado su seguridad carcinologica, bajo reserva de un porcentaje acumulado de tratamiento diferido que oscila entre el 20-50% a los 5 anos. Desde hace varios anos, la vigilancia activa se ha integrado en las recomendaciones de las sociedades cientificas (CC-AFU [Comite de Cancerologie de l’Association Francaise d’Urologie], EAU [European Association of Urology]) como tratamiento de referencia para los CaP de bajo riesgo y, recientemente, como opcion en pacientes seleccionados con un cancer de riesgo intermedio. Los criterios de inclusion varian de un estudio a otro, en particular en terminos de volumen tumoral en las biopsias. El criterio consensuado es la presencia de un cancer del grupo ISUP (International Society of Urological Pathology) 1. La realizacion sistematica de una resonancia magnetica previa a las biopsias, seguida de biopsias dirigidas en caso de lesion, ha permitido reducir el riesgo de reclasificacion y de tratamiento diferido, mejorando asi la seguridad oncologica de los pacientes elegibles. Los biomarcadores, aparte de la densidad del antigeno prostatico especifico, no han mostrado tener un gran interes.
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- 2021
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14. Enfoque diagnóstico del cáncer de próstata: epidemiología, factores de riesgo, detección precoz, biopsias
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Guillaume Ploussard, Pierre Mongiat-Artus, X. Rebillard, and F. Rozet
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03 medical and health sciences ,0302 clinical medicine ,030232 urology & nephrology ,030212 general & internal medicine - Abstract
Resumen El cancer de prostata (CaP) es el cancer mas comun en los varones y la tercera causa de muerte por cancer. Sin embargo, su enfoque diagnostico ha cambiado en los ultimos anos, con un impacto epidemiologico evidente (menor numero de biopsias, reduccion de la mortalidad). Existe la controversia sobre la deteccion del CaP por el antigeno prostatico especifico (PSA), con una mejor comprension de la estrategia de deteccion precoz (enfoque individualizado, no de salud publica) y la confirmacion a largo plazo de la reduccion de la mortalidad especifica por CaP gracias a esta estrategia. Esta estrategia se basa en los antecedentes familiares, la prueba de PSA y el tacto rectal. Se han desarrollado numerosos marcadores moleculares, tanto en sangre como en orina, para superar las limitaciones de la prueba de PSA, sin traduccion clinica por el momento. Los adelantos corresponden mas bien al campo de las pruebas de imagen. La resonancia magnetica (RM) previa a la biopsia se recomienda ahora porque, combinada con las biopsias dirigidas, mejora la deteccion de los CaP clinicamente significativos. El lugar de las biopsias sistematicas, efectuadas esencialmente por via transrectal, sigue siendo importante debido a las limitaciones aun presentes de la RM (disponibilidad, experiencia del radiologo, falsos negativos).
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- 2020
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15. Long-term results of immobilization for ankle tbc in children. F. Rozet (Revue d'orthopédie, 1927, no. 2)
- Author
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Alekseeva-Kozmina, A., primary
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- 1928
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16. Renal tumor biopsy does not increase the risk of surgical complications of minimally invasive partial nephrectomy
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D. Pasquier, F. Rozet, A. Fregeville, E. Barret, C. Lanz, P. Macek, Y. Barbe, N. Cathala, A. Mombet, M. Lefèvre, and X. Cathelineau
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Treatment Outcome ,Robotic Surgical Procedures ,Urology ,Biopsy ,Humans ,Warm Ischemia ,Carcinoma, Renal Cell ,Nephrectomy ,Kidney Neoplasms ,Retrospective Studies - Abstract
For patients with cT1 renal lesions, Partial Nephrectomy (PN) is the gold standard treatment. However, 20% of small renal masses are benign, situation in which the PN is an overtreatment. The percutaneous Renal Tumor Biopsy (RTB) may lower the risk of overtreatment as there is a 90% concordance rate on histotype between the RTB and the final pathology. It has been suggested that the RTB could increase the difficulty of the PN and increase the risk of surgical complications.To compare surgical outcomes and complications of PN with or without previous RTB.monocentric retrospective review of patients who underwent laparoscopic or robotic-assisted PN between January 2012 and December 2019.perioperative complications were recorded using Clavien-Dindo classification, peroperative data included operative time, clamping time and blood loss, and histological outcomes of RTB and PN.In total, 163 patients were included in our study. There were significantly less benign lesions in PN with prior RTB: 7% (4/56) vs. 20% (22/107) without prior RTB (P=0.03). There were no significant differences regarding Clavien-Dindo2 perioperative complications with respectively 7% (4/56) vs. 10% (11/107) (P=0.57). Same goes for peroperative data such as duration of surgery (P=0.81), warm ischemia (P=0.07) and blood loss (P=0.13).RTB does not increase the risk of surgical complications of PN and may reduce the risk of small renal masses overtreatment.
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- 2021
17. [Rectourethral fistula treatment using the modified York Mason technique: Failure factors assessment]
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C, Lainé, F, Rozet, A, Mombet, N, Cathala, E, Barret, R, Sanchez Salas, P, Macek, Y, Barbe, and X, Cathelineau
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Male ,Prostatectomy ,Urinary Fistula ,Urethral Diseases ,Humans ,Rectal Fistula ,Aged ,Retrospective Studies - Abstract
To assess surgical outcomes and failure factors in the management of rectourethral fistulas treated surgically with the modified York Mason technique based on our center's 25 years of experience.From 1997 to 2021, in a single center study, a total of 35 consecutive patients, underwent rectourethral fistula cure, using the modified York Mason technique. Preoperative patient data, surgical outcomes and failure factors were assessed.Of the 35 patients, 28 were successfully managed without the need of further intervention (80%). Median age was 67 years (IQR 62-72) and median follow-up time was 71 months (IQR 30-123). There was no significant difference between the patients that had recurrence or not after the first York Mason.The modified York Mason technique offers a high success rate for the cure of iatrogenic rectourethral fistulas. No predictive factor of failure, after a first cure of recto-uretral fistula by modified York-Mason technique was reported.3.
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- 2021
18. Recommandations françaises du comité de cancérologie de l’AFU pour le cancer de la prostate : cancer de prostate métastatique hormono-naïf – actualisation 2017
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F. Rozet, C. Hennequin, P. Mongiat-Artus, P. Beuzeboc, J.-B. Beauval, L. Cormier, G. Fromont-Hankard, A. Ouzzane, G. Ploussard, R. Renard-Penna, and A. Méjean
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Urology - Published
- 2018
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19. 5-year outcomes of High-Intensity Focused Ultrasound (HIFU) treatment of localised prostate cancer
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C. Deleuze, E. Barret, A. Fregeville, F. Rozet, P. Macek, Y. Barbe, C. Lainé, Q. Mandoorah, A. Mombet, N. Cathala-Mignon, and X. Cathelineau
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Urology - Published
- 2022
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20. Long-term results of immobilization for ankle tbc in children. F. Rozet (Revue d'orthopédie, 1927, no. 2)
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A. Alekseeva-Kozmina
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General Medicine - Abstract
The author gives statistics of 104 cases of ankle tbc in children under 16 years of age treated with immobilization with plaster casts. Observations are taken for the period from 1898 to 1922, and the long-term results are traced in each case for more than 3 years.
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- 1928
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21. Visceral and gastrointestinal complications in robotic urologic surgery
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G. Velilla, C. Redondo, R. Sánchez-Salas, F. Rozet, and X. Cathelineau
- Subjects
03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,030232 urology & nephrology ,General Medicine - Published
- 2018
- Full Text
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22. Management of local relapse after prostate cancer radiotherapy: Surgery or radiotherapy?
- Author
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F. Rozet, C. Hennequin, and J.-M. Hannoun-Lévi
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Brachytherapy ,030232 urology & nephrology ,Salvage therapy ,Cryotherapy ,Stereotactic radiation therapy ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Prostatectomy ,Salvage Therapy ,business.industry ,Prostatic Neoplasms ,Cancer ,medicine.disease ,Surgery ,Radiation therapy ,Oncology ,030220 oncology & carcinogenesis ,Neoplasm Recurrence, Local ,business - Abstract
Isolated local relapse after prostate cancer radiotherapy corresponds to 40% of biochemical failure. The management of these relapses is not well defined. Several strategies are available including surgery, high-intensity focused ultrasounds (HIFU), cryotherapy and reirradiation. Radical prostatectomy is the historical approach; biochemical control is obtained in 50 to 80% at 5 year. However, morbidity is higher after irradiation than as a first line treatment. Some limited series of HIFU and cryotherapy have been published with interesting results, but again the risk of urinary and rectal toxicity is high. However, new generation technologies could decrease the complication rate. Reirradiation could be performed with brachytherapy and more recently with stereotactic radiation therapy. The results of salvage low-dose-rate brachytherapy have been reported in some series with a 5-year biochemical control rate of 34 to 88%. High-dose rate brachytherapy seems to be better tolerated, but the number of patients treated and reported is too low to draw firm conclusions. This is the same for stereotactic radiation therapy salvage treatment. A prospective trial of salvage brachytherapy (CAPRICUR) is now open in France and inclusion in this trial is recommended.
- Published
- 2017
- Full Text
- View/download PDF
23. [Recommendations CCAFU on the management of cancers of the urogenital system during an epidemic with Coronavirus COVID-19]
- Author
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A, Méjean, M, Rouprêt, F, Rozet, K, Bensalah, T, Murez, X, Game, X, Rebillard, R, Mallet, A, Faix, P, Mongiat-Artus, G, Fournier, and Y, Neuzillet
- Subjects
Male ,Infection Control ,Infectious Disease Transmission, Patient-to-Professional ,SARS-CoV-2 ,Urologists ,Decision Making ,Pneumonia, Viral ,COVID-19 ,Disease Management ,Betacoronavirus ,Humans ,Coronavirus Infections ,Epidemics ,Pandemics ,Societies, Medical ,Urogenital Neoplasms - Abstract
The French population is facing the COVID-19 pandemic and the health system have been reoriented in emergency for the care of patients with coronavirus. The management of cancers of the urinary and male genital tracts must be adapted to this context.An expert opinion documented by a literature review was formulated by the Cancerology Committee of the French Association of Urology (CCAFU).The medical and surgical management of patients with any cancers of the urinary and male genital tracts must be adapted by modifying the consultation methods, by prioritizing interventions according to the intrinsic prognosis of cancers, taking into account the patient's comorbidities. The protection of urologists from COVID-19 must be considered.The CCAFU issues an expert opinion on the measure to be taken to adapt the management of cancers of the male urinary and genital tract to the context of pandemic by COVID-19.
- Published
- 2020
24. [Localized Prostate cancer in candidates for renal transplantation and recipients of a kidney transplant: The French Guidelines from CTAFU]
- Author
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T, Culty, A, Goujon, G, Defortescu, T, Bessede, F, Kleinclauss, R, Boissier, S, Drouin, J, Branchereau, A, Doerfler, T, Prudhomme, X, Matillon, G, Verhoest, X, Tillou, G, Ploussard, F, Rozet, A, Méjean, and M-O, Timsit
- Subjects
Male ,Postoperative Complications ,Humans ,Kidney Failure, Chronic ,Prostatic Neoplasms ,Kidney Transplantation - Abstract
To define guidelines for the management of localized prostate cancer (PCa) in kidney transplant (KTx) candidates and recipients.A systematic review (Medline) of the literature was conducted by the CTAFU to report prostate cancer epidemiology, screening, diagnosis and management in KTx candidates and recipients with the corresponding level of evidence.KTx recipients are at similar risk for PCa as general population. Thus, PCa screening in this setting is defined according to global French guidelines from CCAFU. Systematic screening is proposed in candidates for renal transplant over 50 y-o. PCa diagnosis is based on prostate biopsies performed after multiparametric MRI and preventive antibiotics. CCAFU guidelines remain applicable for PCa treatment in KTx recipients with some specificities, especially regarding lymph nodes management. Treatment options in candidates for KTx need to integrate waiting time and access to transplantation. Current data allows the CTAFU to propose mandatory waiting times after PCa treatment in KTx candidates with a weak level of evidence.These French recommendations should contribute to improve PCa management in KTx recipients and candidates, integrating oncological objectives with access to transplantation.
- Published
- 2020
25. [French CCAFU guidelines on prostate cancer: hormone-sensitive metastatic prostate cancer-update 2020]
- Author
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F, Rozet, C, Hennequin, P, Beuzeboc, R, Mathieu, P, Mongiat-Artus, J-B, Beauval, L, Cormier, G, Fromont-Hankard, G, Ploussard, R, Renard-Penna, L, Brureau, and A, Méjean
- Subjects
Male ,Humans ,Prostatic Neoplasms ,Androgen Antagonists ,Neoplasm Metastasis - Abstract
The aim of the Cancerology Committee of the French Association of urology (CCAFU) is to propose an update of the guidelines in the management of hormone-sensitive metastatic prostate cancer.A systematic review (Medline) of the literature from 2018 to 2020 was conducted by the CCAFU Findings. Several patterns can be defined at this stage depending on prognostic, metastatic volume, and whether metastases are synchronous or metachronous. Androgenic deprivation therapy (ADT) remains the mainstay of treatment at the metastatic stage. Docetaxel in combination with ADT improves overall survival in synchronous metastatic prostate cancer. In this situation, the combination of ADT with abiraterone is also a standard of care regardless of tumor volume. Recent data have led to the recommendation that ADT should be used in conjunction with a new generation hormone therapy (Apalutamide or Enzalutamide) in metastatic synchronous or metachronous patients, regardless of tumour volume. Local treatment of prostate cancer with radiotherapy improves survival in synchronous oligometastatic patients. Metastases-directed therapy is being evaluated.This update of the French recommendations should help improve the management of patients with prostate cancer.
- Published
- 2020
26. Maladie thromboembolique veineuse et cancers urologiques : épidémiologie et prise en charge thérapeutique
- Author
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M, Felber, F, Rozet, S, Droupy, V, Misraï, D M, Smadja, M, Rouprêt, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service d'urologie [Institut Mutualiste Montsouris], Institut Mutualiste de Montsouris (IMM), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Clinique Pasteur [Toulouse], Innovations thérapeutiques en hémostase (IThEM - U1140), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), and CCSD, Accord Elsevier
- Subjects
Urologic Neoplasms ,Prophylaxis ,Incidence ,Urology ,Bladder cancer ,Cancer de vessie ,Pulmonary embolism ,Prostate ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,equipment and supplies ,[SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology ,[SDV.MHEP.UN] Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology ,Renal cell carcinoma ,Carcinome à cellules claires ,[SDV.CAN] Life Sciences [q-bio]/Cancer ,Prophylaxie ,Humans ,Neoplasm ,cardiovascular diseases ,Thrombose veineuse ,Urologie ,Cancer ,Embolie pulmonaire ,Venous thromboembolism - Abstract
Active cancer is a risk factor in the occurrence of venous thromboembolism (VTE). This is the second cause of death for these patients. In onco-urology, some cancers are associated with an increased risk of VTE. The aim of this study was to propose a focus of epidemiology and VTE therapy management.A systematic analysis of the PubMedThe incidence of VTE was more important in case of renal carcinomas (3.5%/year). When surgery was proposed cystectomy was the riskiest procedure (2.6 to 11.6% VTE). Chemotherapy alone was an important risk factor increasing by a factor of six the occurrence of VTE. Hormonotherapy also increased this risk by induced hypogonadism. The curative treatment for VTE associated with cancers has to be performed through the injection of low molecular weight heparin. The implantation of a prophylactic treatment was not systematic among patients diagnosed with urological cancer.The understanding of mechanisms associated with the occurrence of VTE among these patients has enabled to improve patient management, especially those suffering from urological cancer. Undeniably, frequency of VTE is probably underestimated by urologists during clinical practice.
- Published
- 2019
- Full Text
- View/download PDF
27. RETRACTED: Actualisation 2018–2020 des recommandations françaises du Comité de cancérologie de l’AFU – ÉditorialUpdate 2018–2020 of French ccAFU guidelines – Editorial
- Author
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A, Méjean, K, Bensalah, T, Murez, M, Rouprêt, and F, Rozet
- Abstract
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). Cet article est retiré de la publication à la demande des auteurs car ils ont apporté des modifications significatives sur des points scientifiques après la publication de la première version des recommandations. Le nouvel article est disponible à cette adresse: doi: 10.1016/j.purol.2019.01.003. C’est cette nouvelle version qui doit être utilisée pour citer l’article. This article has been retracted at the request of the authors, as it is not based on the definitive version of the text because some scientific data has been corrected since the first issue was published. The replacement has been published at the doi: 10.1016/j.purol.2019.01.003. That newer version of the text should be used when citing the article.
- Published
- 2018
28. RETRACTED: Recommandations françaises du Comité de Cancérologie de l’AFU – Actualisation 2018–2020 : cancer de la prostate French ccAFU guidelines – Update 2018–2020: Prostate cancer
- Author
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F, Rozet, C, Hennequin, J-B, Beauval, P, Beuzeboc, L, Cormier, G, Fromont-Hankard, P, Mongiat-Artus, G, Ploussard, R, Mathieu, L, Brureau, A, Ouzzane, D, Azria, I, Brenot-Rossi, G, Cancel-Tassin, O, Cussenot, X, Rebillard, T, Lebret, M, Soulié, R Renard, Penna, and A, Méjean
- Subjects
Male ,Humans ,Prostatic Neoplasms ,France ,Practice Patterns, Physicians' ,Medical Oncology ,Societies, Medical - Abstract
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). Cet article est retiré de la publication à la demande des auteurs car ils ont apporté des modifications significatives sur des points scientifiques après la publication de la première version des recommandations. Le nouvel article est disponible à cette adresse: DOI:10.1016/j.purol.2019.01.007. C’est cette nouvelle version qui doit être utilisée pour citer l’article. This article has been retracted at the request of the authors, as it is not based on the definitive version of the text because some scientific data has been corrected since the first issue was published. The replacement has been published at the DOI:10.1016/j.purol.2019.01.007. That newer version of the text should be used when citing the article.
- Published
- 2018
29. [Interest of a systematic assessment of the treatment of the lower urinary tract symptoms in the management of benign prostatic hypertrophy in general practice (1380 patients) - Study EVALURO]
- Author
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A, Descazeaud, P, Coloby, A, De La Taille, G, Kouri, R, Mallet, D, Rossi, F, Rozet, M, Zerbib, and F, Carrois
- Subjects
Aged, 80 and over ,Male ,Plant Extracts ,General Practice ,Prostatic Hyperplasia ,Middle Aged ,Treatment Outcome ,Lower Urinary Tract Symptoms ,General Practitioners ,Quality of Life ,Humans ,France ,Prospective Studies ,Adrenergic alpha-Antagonists ,Aged ,Follow-Up Studies - Abstract
To evaluate the efficacy of a modification or initiation of treatment by a α-blocker in patients already medically treated for BPH-related LUTS, with persistent urinary symptoms.This is a prospective observational study among general practitioners in France. Included patients were over 60 years of age with BPH-related LUTS who had been medically treated for at least 6 months. A treatment by an α-blocker was initiated or modified if the PGI-I (Patient Global Impression of Improvement) did not objective any improvement under treatment and the IPSS (International Prostate Symptom Score) was≥8. Patients were followed up between 1 and 3 months after inclusion. The primary endpoint was the frequency of unsatisfactory progression of patients, assessed by persistence of urinary symptoms under treatment (IPSS≥8 and PGI-I unchanged or worsened). Progress of LUTS (IPSS and PGI-I) following modification of treatment with α-blocker was also assessed at the follow-up visit.Three hundred and fifty-three physicians included 1449 patients between February 2, 2016 and March 9, 2017 (1380 patients were analyzed): the average age was 70.0±6.9 years ; the duration of the LUTS was 4.1±4.2 years; at inclusion, they received mainly plants (n=744; 53.9%) and α-blockers (n=463; 33.6%); the mean IPSS score was 16.4±6.7, it was not correlated with duration of SBAU; the mean PGi-I was 2.6±1.2. In total, 48.8% (612/1255) of patients had a non-satisfactory evaluation of the LUTS; 42.8% (591/1380) of patients had a modification of treatment according to the protocol: 385 (65.6%) had an initiation of a α-blocker, 202 (34.4%) had a modification of treatment by α-blocker (4 missing data). The α-blocker was monotherapy for 484 (81.9%) patients. At the follow-up visit (1 to 3 months), the average IPSS score was 7.7±4.8, significantly lower (18.7±6.1 at inclusion); the average PGI-I of 1.2±0.7 was significantly lower (3.5±0.8 at inclusion); the quality of life (Q8-IPSS) was significantly improved. For the 345 patients under plant extracts having changed for one α-blocker, as well as for the 67 patients under α-blocker having changed for another α-blocker, the 3 scores had decreased significantly.A systematic evaluation of medical treatment for BPH showed that 48.8% of patients medically treated for at least 6 months were not improved. A modification of treatment by an α-blocker (initiation or modification) can then significantly improve the LUTS.
- Published
- 2018
30. [French CCAFU guidelines on prostate cancer: hormono-naive metastatic prostate cancer - update 2017]
- Author
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F, Rozet, C, Hennequin, P, Mongiat-Artus, P, Beuzeboc, J-B, Beauval, L, Cormier, G, Fromont-Hankard, A, Ouzzane, G, Ploussard, R, Renard-Penna, and A, Méjean
- Subjects
Male ,Therapies, Investigational ,Abiraterone Acetate ,Prostatic Neoplasms ,Medical Oncology ,Survival Analysis ,Clinical Trials, Phase III as Topic ,Evidence-Based Practice ,Humans ,France ,Neoplasm Metastasis ,Practice Patterns, Physicians' ,Societies, Medical ,Randomized Controlled Trials as Topic - Published
- 2018
31. Predictors of early, intermediate and late biochemical recurrence after minimally invasive radical prostatectomy in a single-centre cohort with a mean follow-up of 8 years
- Author
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S, García-Barreras, I, Nunes, V, Srougi, F, Secin, M, Baghdadi, R, Sánchez-Salas, E, Barret, F, Rozet, M, Galiano, and X, Cathelineau
- Subjects
Male ,Prostatectomy ,Time Factors ,Prostatic Neoplasms ,Middle Aged ,Prostate-Specific Antigen ,Prognosis ,Robotic Surgical Procedures ,Humans ,Minimally Invasive Surgical Procedures ,Laparoscopy ,Neoplasm Recurrence, Local ,Aged ,Follow-Up Studies ,Retrospective Studies - Abstract
To determine the predictors of early, intermediate and late biochemical recurrence (BR) following minimally invasive radical prostatectomy in patients with localised prostate cancer (PC).We included 6195 patients with cT1-3N0M0 prostate cancer treated using radical laparoscopic prostatectomy (RLP) and radical robot-assisted prostatectomy at our institution between 2000 and 2016. None of the patients underwent adjuvant therapy. BR is defined as PSA levels ≥0.2 ng/dL. The time to BR is divided into terciles to identify the variables associated with early (12 months), intermediate (12-36 months) and late (36 months) recurrence. We employed logistic regression models to determine the risk factors associated with each interval.We identified 1148 (18.3%) patients with BR. The median time to BR was 24 months (IQR, 0.98-53.18). The multivariate analysis showed that preoperative PSA levels, lymph node invasion, positive margins and RLP are associated with early recurrence (P≤.029 for all). Laparoscopic surgery was the only predictor of intermediate recurrence (P=.001). The predictors of late recurrence included a pathological Gleason score ≥7, stage ≥pT3, positive margins and RLP (P≤.02 for all).The patients with high-risk prostate cancer can develop late recurrence and require long-term follow-up. Identifying patients with higher PSA levels and lymph node invasion has an important predictive role in the first year after surgery. The association between RLP and BR warrants further assessment.
- Published
- 2017
32. [Management of ablative therapies in prostate cancer]
- Author
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E, Barret, R, Sanchez-Salas, M, Galiano, N, Cathala, A, Mombet, D, Prapotnich, F, Rozet, A, Gangi, H, Lang, and X, Cathelineau
- Subjects
Ablation Techniques ,Male ,Patient Care Team ,Postoperative Care ,Patient Education as Topic ,Humans ,Prostatic Neoplasms ,Thrombosis ,Antibiotic Prophylaxis ,Phototherapy - Abstract
To describe the specific modalities of ablative therapies management in prostate cancer.A review of the scientific literature was performed in Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) using different associations of keywords. Publications obtained were selected based on methodology, language and relevance. After selection, 61 articles were analysed.Development of innovations such as ablative therapies in prostate cancer induces specific modalities in their management, during pre-, per- and post-procedure. More than for classical and well-known treatments, the decision to propose an ablative therapy requires analysis and consensus of medical staff and patient's agreement. Patient's specificities and economical aspects must also be considered. Procedures and follow-up must be realized by referents actors.Indication, procedure and follow-up of ablative therapies in prostate cancer require specific modalities. They must be respected in order to optimize the results and to obtain a precise and objective evaluation for defining future indications.
- Published
- 2017
33. [Active surveillance of prostate cancer]
- Author
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G, Ploussard, C, Hennequin, and F, Rozet
- Subjects
Male ,Patient Selection ,Humans ,Prostatic Neoplasms ,Watchful Waiting - Abstract
Several prospective studies have demonstrated the safety of active surveillance as a first treatment of prostate cancer. It spares many patients of a useless treatment, with its potential sequelae. Patients with a low-risk cancer are all candidates for this approach, as recommended by the American Society of Clinical Oncology (ASCO). Some patients with an intermediate risk could be also concerned by active surveillance, but this is still being discussed. Currently, the presence of grade 4 lesions on biopsy is a contra-indication. Modalities included a repeated prostate specific antigen test and systematic rebiopsy during the first year after diagnosis. MRI is now proposed to better select patients at inclusion and also during surveillance. No life style changes or drugs are significantly associated with a longer duration of surveillance.
- Published
- 2017
34. Actualisation 2018–2020 des recommandations françaises du Comité de Cancérologie de l’AFU – Éditorial
- Author
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A. Méjean, K. Bensalah, T. Murez, M. Rouprêt, and F. Rozet
- Subjects
Urology - Published
- 2018
- Full Text
- View/download PDF
35. Comparison of cancer detection rates in micro-ultrasound biopsies versus robotic ultrasound-magnetic resonance imaging fusion biopsies for prostate cancer
- Author
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O. Rojas Claros, F. Muttin, R.R.T. Barbosa, A.C. Gallardo, E. Barret, F. Rozet, N. Cathala, D. Prapotnich, A. Mombet, R. Sanchez-Salas, and X. Cathelineau
- Subjects
Urology - Published
- 2019
- Full Text
- View/download PDF
36. [Management of a progressing prostate cancer: results of a national study]
- Author
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F, Rozet, M, Roupret, C, Hennequin, C, Massard, P, Blanchard, and S, Le Moulec
- Subjects
Male ,Prostatectomy ,Prostatic Neoplasms, Castration-Resistant ,Health Care Surveys ,Disease Progression ,Humans ,Prostatic Neoplasms ,France ,Aged - Abstract
The introduction of new treatments in metastatic castration resistant prostate cancer (mCRPC) requires a close follow-up to detect a progression and then to adapt the treatment. In that context, a national survey was proposed to a group of experts and the aim was to identify the modalities of surveillance in different clinical situations.A questionnaire was sent to 1464 urologists, medical oncologists and radiotherapists, about a clinical case; it was about a patient presenting a prostate cancer, evolving from a biologic progression after radical prostatectomy to a situation of metastasis resistant to the castration. The questionnaire contained ten questions about reasons of changing treatment because of progression, and about modalities of the follow-up.A total of 318 questionnaires were analyzed (response rate of 22%). The results showed comparable practices between the different types of specialists, even if a more frequent rhythm of surveillance was reported by medical oncologists and radiotherapists. At progression after radical prostatectomy, a clinical and biological surveillance was generally realized every 3 or 6 months, and imaging exams were done on demand. Then, as the cancer progresses, the surveillance became systematic and more and more close, with imaging done every 3 months or on demand. While the definition of progression was essentially based on PSA testing at the beginning of the castration resistance, it then combines different clinical, biological and radiological criteria.There are few recommendations available about follow-up of patients with a mCRPC. In that survey, the oncologists and urologists reported a more intensive rhythm of surveillance as the prostate cancer progresses.4.
- Published
- 2017
37. Prostate-Sparing Radical Cystectomy for Selected Patients with Bladder Cancer
- Author
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Eric Barret, X Cathelineau, P. Macek, Rafael Sanchez-Salas, F Rozet, Marc Galiano, and Tomáš Hanuš
- Subjects
Male ,Risk ,Oncology ,medicine.medical_specialty ,Referral ,Urology ,medicine.medical_treatment ,Population ,MEDLINE ,Cystectomy ,Disease-Free Survival ,Recurrence ,Prostate ,Internal medicine ,medicine ,Carcinoma ,Humans ,education ,education.field_of_study ,Bladder cancer ,business.industry ,Incidence ,Patient Selection ,General surgery ,Prostatic Neoplasms ,medicine.disease ,Treatment Outcome ,medicine.anatomical_structure ,Urinary Bladder Neoplasms ,Prostate surgery ,business - Abstract
Objectives: To review the current literature about prostate-sparing radical cystectomy (PSRC) and its potential for management of a selected population of patients with bladder cancer. Materials and Methods: The PubMed, EMBASE and Scopus databases were searched for the key words ‘prostate', ‘sparing' and ‘cystectomy' between 1984 and 2012. Articles in English, French and German were considered relevant for review. Institutional experience with this procedure was also included. Results: PSRC remains a controversial procedure for the treatment of patients harboring bladder carcinoma, mainly due to insufficient knowledge of clear indications and/or contraindications. Experience with PSRC is still limited to very few referral centers and there is a lack of large series with long-term outcomes. The potential for excellent functional outcomes must be carefully balanced against inconsistent oncological results. Conclusions: PSRC may become an option for carefully selected and extensively informed patients. Suggestions for possible indications and contraindications are presented.
- Published
- 2013
- Full Text
- View/download PDF
38. [CCAFU french national guidelines 2016-2018 on prostate cancer]
- Author
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F, Rozet, C, Hennequin, J-B, Beauval, P, Beuzeboc, L, Cormier, G, Fromont, P, Mongiat-Artus, A, Ouzzane, G, Ploussard, D, Azria, I, Brenot-Rossi, G, Cancel-Tassin, O, Cussenot, T, Lebret, X, Rebillard, M, Soulié, R, Renard-Penna, and A, Méjean
- Subjects
Male ,Humans ,Prostatic Neoplasms - Abstract
The purpose of the guidelines national committee CCAFU was to propose updated french guidelines for localized and metastatic prostate cancer (PCa).A Medline search was achieved between 2013 and 2016, as regards diagnosis, options of treatment and follow-up of PCa, to evaluate different references with levels of evidence.Epidemiology, classification, staging systems, diagnostic evaluation are reported. Disease management options are detailed. Recommandations are reported according to the different clinical situations. Active surveillance is a major option in low risk PCa. Radical prostatectomy remains a standard of care of localized PCa. The three-dimensional conformal radiotherapy is the technical standard. A dose of74Gy is recommended. Moderate hypofractionation provides short-term biochemical control comparable to conventional fractionation. In case of intermediate risk PCa, radiotherapy can be combined with short-term androgen deprivation therapy (ADT). In case of high risk disease, long-term ADT remains the standard of care. ADT is the backbone therapy of metastatic disease. In men with metastases at first presentation, upfront chemotherapy combined with ADT should be considered as a new standard. In case of metastatic castration-resistant PCa (mCRPC), new hormonal treatments and chemotherapy provide a better control of tumor progression and increase survival.These updated french guidelines will contribute to increase the level of urological care for the diagnosis and treatment for prostate cancer. © 2016 Elsevier Masson SAS. All rights reserved.
- Published
- 2016
39. [Comments on the ProtecT test]
- Author
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F, Rozet and C, Hennequin
- Subjects
Urologic Diseases ,Humans - Published
- 2016
40. [Localized prostate cancer Focal Therapy: 'A la carte' Model]
- Author
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E, Linares Espinós, E, Barret, A, Sivaraman, J I, Pérez-Reggeti, R, Sánchez-Salas, F, Rozet, M, Galiano, and X, Cathelineau
- Subjects
Male ,Humans ,Prostatic Neoplasms ,Organ Sparing Treatments ,Patient Care Planning - Abstract
Focal therapy has settled as an alternative to radical treatment in selected cases of localized prostate cancer. The selection of patients who are candidates for focal therapy is based on imaging diagnosis relying on multiparametric MRI and image fusion techniques. Thanks to the oncological results and safety profiles of initial series, various energy sources have been developed over the last years. The availability of multiple types of energy sources for focal therapy, commits us to evaluate what type of energy would be the optimal depending on patient's profile and type of lesion. A unique energy for focal therapy would be ideal, but facing the research of the various types of energy we must identify which one is recommended for each lesion. With the experience of our center in different approaches of focal therapy we propose the "A LA CARTE" MODEL based on localization of the lesion. We present the criteria the "a la carte" model is based on, supported by the published evidence on the use of different ablative therapies for the treatment of localized prostate cancer. Lesion localization, technical characteristics of each type of energy, patient's profile and secondary effects must be considered in every choice of focal therapy.
- Published
- 2016
41. Systematic review of perioperative outcomes and complications after open, laparoscopic and robot-assisted radical cystectomy
- Author
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A, Palazzetti, R, Sanchez-Salas, P, Capogrosso, E, Barret, N, Cathala, A, Mombet, D, Prapotnich, M, Galiano, F, Rozet, and X, Cathelineau
- Subjects
Postoperative Complications ,Treatment Outcome ,Robotic Surgical Procedures ,Humans ,Laparoscopy ,Cystectomy - Abstract
Radical cystectomy and regional lymph node dissection is the standard treatment for localized muscle-invasive and for high-risk non-muscle-invasive bladder cancer, and represents one of the main surgical urologic procedures. The open surgical approach is still widely adopted, even if in the last two decades efforts have been made in order to evaluate if minimally invasive procedures, either laparoscopic or robot-assisted, might show a benefit compared to the standard technique. Open radical cystectomy is associated with a high complication rate, but data from the laparoscopic and robotic surgical series failed to demonstrate a clear reduction in post-operative complication rates compared to the open surgical series. Laparoscopic and robotic radical cystectomy show a reduction in blood loss, in-hospital stay and transfusion rates but a longer operative time, while open radical cystectomy is typically associated with a shorter operative time but with a longer in-hospital admission and possibly a higher rate of high grade complications.
- Published
- 2016
42. Quelle prise en charge après prostatectomie totale ?
- Author
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J. L. Davin, F. Rozet, and I. Latorzeff
- Subjects
Gynecology ,medicine.medical_specialty ,Adjuvant radiotherapy ,Oncology ,business.industry ,Salvage radiotherapy ,medicine ,business - Abstract
Certains patients apres une prostatectomie totale sont a risque de rechute. Cette rechute peut etre due a la presence de micrometastases au moment du diagnostic. Les resultats d’essais therapeutiques randomises prospectifs conduits chez des patients a haut risque de rechute ont montre que l’utilisation de la radiotherapie postoperatoire adjuvante permettait d’ameliorer la survie sans progression et la survie sans metastase et le controle local. Les patients qui n’ont pas recu de radiotherapie adjuvante mais qui rechutent secondairement sont candidats a une irradiation de rattrapage. L’hormonotherapie se discute egalement dans cette indication. Les resultats encourageants de la chimiotherapie moderne en phase avancee de la maladie permettent de tester cette attitude therapeutique a une phase plus precoce a la rechute biologique actuellement. Cet article se propose de faire le point des criteres de decision de l’utilisation de ces traitements pour la prise en charge de ces patients a haut risque et des essais en cours en situation adjuvante ou de rattrapage.
- Published
- 2012
- Full Text
- View/download PDF
43. Place et principes de la radiothérapie dans le cancer de la prostate du sujet âgé
- Author
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V. Molinié, C. Bastide, F. Rozet, Pierre Richaud, P. Beuzeboc, F. Cornud, N. Gaschignard, L. Salomon, F. Staerman, M. Soulié, P. Mongiat-Artus, and M. Peyromaure
- Subjects
Oncology ,education.field_of_study ,medicine.medical_specialty ,business.industry ,Urology ,medicine.medical_treatment ,Standard treatment ,Population ,medicine.disease ,Surgery ,Radiation therapy ,Health problems ,Prostate cancer ,Internal medicine ,Life expectancy ,Medicine ,Hormonal therapy ,Hormone therapy ,business ,education - Abstract
The aging of the population has resulted in an increase in the number of elderly patients with prostate cancer. Among the curative treatment options in the elderly subject, external radiotherapy is the most frequently chosen option. Combined treatment including radiotherapy and hormone therapy should be preferred to hormonal therapy alone, including in elderly patients, whenever life expectancy surpasses 4-5 years. The indications for this radiotherapy should be defined in an attempt to prevent excessive or insufficient treatment, to adapt the treatment modalities to the patient's age by assessing its potential toxicity, and to discuss the possible alternatives. In cases of localized prostate cancer in men who are aging well, a standard treatment should be proposed, preferring radiotherapy possibly associated with hormone therapy in cases with negative prognostic factors. Patients with a reversible health problems can also receive standard treatment, notably in cases with aggressive prognostic factors.
- Published
- 2009
- Full Text
- View/download PDF
44. High intensity focused ultrasound with Focal-One
- Author
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J I, Perez-Reggeti, R, Sanchez-Salas, A, Sivaraman, E, Linares Espinos, A E, de Gracia-Nieto, E, Barret, M, Galiano, F, Rozet, A, Fregeville, R, Renard-Penna, N, Cathala, A, Mombet, D, Prapotnich, and X, Cathelineau
- Subjects
Male ,Prostatectomy ,Postoperative Complications ,Treatment Outcome ,High-Intensity Focused Ultrasound Ablation ,Humans ,Prostatic Neoplasms ,Prostate-Specific Antigen ,Aged ,Retrospective Studies - Abstract
We report our initial experience in the treatment of prostate cancer (PCa) with high-intensity focused ultrasound (HIFU) using the Focal-OneRetrospective review of the prospectively populated database. Between June 2014 to October 2015, 85 patients underwent HIFU (focal/whole-gland) treatment for localized PCa. Preoperative cancer localization was done with multiparametric magnetic resonance imaging (mpMRI) and transperineal mapping biopsies. Treatment was carried out using the Focal-OneThe median PSA was 7.79ng/ml (IQR 6.32-9.16), with a median prostate volume of 38cc (IQR: 33-49.75). Focal and whole-gland therapy was performed in 64 and 21 patients respectively. Ten patients received salvage HIFU. Complications were encountered in 15% of cases, all Clavien 2 graded. Mean hospital stay was 1.8 days (0-7) and bladder catheter was removed on day 2 (1-6). Mean percentage reduction of PSA was 54%. Median follow-up was 3 months (IQR: 2-8). Functional outcomes: All patients were continents at 3 months and potency was maintained in 83% of the preoperatively potent.Focal-One
- Published
- 2016
45. Clinical performance of transperineal template guided mapping biopsy for therapeutic decision making in low risk prostate cancer
- Author
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Y, Ahallal, R, Sanchez-Salas, A, Sivaraman, E, Barret, F P, Secin, P, Validire, F, Rozet, M, Galiano, and X, Cathelineau
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Image-Guided Biopsy ,Male ,Clinical Decision-Making ,Prostate ,Humans ,Prostatic Neoplasms ,Middle Aged ,Peritoneum ,Risk Assessment ,Aged ,Retrospective Studies - Abstract
To evaluate the role of Transperineal Template guided Mapping Biopsy (TTMB) in determining the management strategy in patients with low risk prostate cancer (PCa).We retroscpectively evaluated 169 patients who underwent TTMB at our institution from February 2008 to June 2011. Ninety eight of them harbored indolent PCa defined as: Prostate Specific Antigen10ng/ml, Gleason score 6 or less, clinical stage T2a or less, unilateral disease and a maximum of one third positive cores at first biopsy and50% of the core involved. TTMB results were analyzed for Gleason score upgrading and upstaging as compared to initial TransRectal UltraSound (TRUS) biopsies and its influence on the change in the treatment decisions.TTMB detected cancer in 64 (65%) patients. The upgrade, upstage and both were noted in 33% (n=21), 12% (n=8) and 7% (n=5) respectively of the detected cancers. The disease characteristics was similar to initial TRUS in 30 (48%) patients and TTMB was negative in 34 (35%) patients. Prostate volume was significantly smaller in patients with upgrade and/or upstage noted at TTMB (45.4 vs 37.9; P=.03). TTMB results influenced 73.5% of upgraded and/or upstaged patients to receive radical treatment while 81% of the patients with unmodified stage and/or grade continued active surveillance or focal therapy.In patients with low risk PCa diagnosed by TRUS, subsequent TTMB demonstrated cancer upgrade and/or upstage in about one-third of the patients and resulted in eventual change in treatment decision.
- Published
- 2016
46. [Not Available]
- Author
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R, Renard-Penna, C, Borgogno, P, Puech, O, Rouvière, A, Mejean, and F, Rozet
- Published
- 2015
47. [Not Available]
- Author
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T, Seisen, P, Colin, V, Hupertan, P, Léon, G, Bozzini, L, Nison, V, Phé, F, Rozet, S, Shariat, O, Cussenot, and M, Rouprêt
- Published
- 2015
48. [Surgery of prostate cancer: Technical principles and perioperative complications]
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L, Salomon, F, Rozet, and M, Soulié
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Male ,Prostatectomy ,Postoperative Complications ,Decision Trees ,Humans ,Prostatic Neoplasms - Abstract
To describe the surgical procedure of localized prostate cancer treated by radical prostatectomy.Bibliography search was performed from the Medline database (National Library of Medicine, PubMed) selected according to the scientific relevance. The research was focused on historic of radical prostatectomy, surgical anatomy, surgical technics of radical prostatectomy and lymph nodes excision, and complications.During the last 30 years, evolution of radical prostatectomy was important, from open to mini-invasive surgery with or without robotic assistance. Anatomical knowledge of the prostate was useful to describe the different anatomical structure as urinary sphincter and fascias, and to develop different procedure of neurovascular bundles preservation to ameliorate functional results. Complications are well-known and their taking-over more precise. Results of radical prostatectomy depend less of the surgical approach but more of the attitude of the surgeon according to the characteristics of the tumor and the functional status of the patient.Radical prostatectomy is an elaborate and challenging procedure when carcinological risk balances with functional results. Nevertheless, complications are quite rare. Improvement of results is due to adequation between surgical procedure and oncological and functional status.
- Published
- 2015
49. Anastomose urétrovésicale lors de la prostatectomie radicale laparoscopique
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G. Fournier, F Rozet, X Cathelineau, G. Vallancien, and E. Barret
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business.industry ,Urology ,Medicine ,Endoscopic surgery ,Prostate disease ,business ,Humanities - Abstract
Resume L'anastomose uretrovesicale est le dernier temps operatoire de la prostatectomie radicale. Quelle que soit la voie d'abord, la prostatectomie radicale est une intervention difficile. Les temps de dissection sont similaires par voie ouverte et par voie laparoscopique. L'anastomose uretrovesicale laparoscopique requiert une gestuelle particuliere. Cette gestuelle doit etre maitrisee par le chirurgien realisant une prostatectomie radicale laparoscopique. Cette technique est codifiee et reproductible. Elle peut etre assimilee sur pelvitrainer avant de commencer a realiser cette intervention par voie laparoscopique. Cet article rapporte les points clefs necessaires a la realisation de l'anastomose uretrovesicale par voie laparoscopique, ainsi que les differentes variations techniques.
- Published
- 2006
- Full Text
- View/download PDF
50. [Imagery of treated prostate cancer]
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R, Renard-Penna, L, Michaud, L, Cormier, C, Bastide, P, Beuzeboc, G, Fromont, C, Hennequin, P, Mongiat-Artus, M, Peyromaure, F, Rozet, P, Richaud, L, Salomon, and M, Soulié
- Subjects
Male ,Fluorine Radioisotopes ,Positron-Emission Tomography ,Humans ,Prostatic Neoplasms ,Neoplasm Recurrence, Local ,Tomography, X-Ray Computed ,Magnetic Resonance Imaging ,Multimodal Imaging ,Choline - Abstract
Diagnosis, localization of recurrence in the management of prostate cancer patients with increasing concentrations of tumor serum markers is crucial for treatment planning of the patients. The present review describes the role of prostate MRI and (18) Fcholine PET/computed tomography (CT) in tumor detection and extent, when there is a suspicion of residual or recurrent disease after treatment of prostate cancer.A systematic review of the literature was performed by searching in the PUB MED/MEDLINE database searching for articles in French or English published between the last 12years.In patient with a clinical suspicion of recurrence after treatment for prostate cancer, imaging can be used to distinguish between local recurrence and metastatic disease. (11)C-choline PET/CT and pelvic multiparametric MR imaging (mp MRI) are complementary in this indication. In this paper, the current status of imaging techniques used for the staging of patients with suspected locally recurrent or metastatic disease in patients treated for prostate cancer were reviewed.Mp MRI of the prostate may be valuable imaging modality for the detection and localization of local recurrence. C-choline PET/CT offers an advantage in detecting metastatic disease to lymph node and bone.
- Published
- 2014
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