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Chemical Structure of an Acylated Oleanane-type Triterpene Oligoglycoside and Anti-inflammatory Constituents from the Flower Buds of Camellia sinensis
- Source :
- Scopus-Elsevier
- Publication Year :
- 2017
- Publisher :
- SAGE Publications, 2017.
-
Abstract
- A new acylated oleanane-type triterpene oligoglycoside, floratheasaponin K (1), was isolated together with 11 known compounds including floratheasaponins D (2)–G (5), and I (6), chakasaponin V (7), and assamsaponin E (8) from the flower buds of Camellia sinensis cultivated in India. The chemical structure of floratheasaponin K (1) was elucidated on the basis of chemical and physicochemical evidence. In addition, chakasaponins V (7) and I (13) significantly inhibited nitric oxide (NO) production in lipopolysaccharide- (LPS) activated RAW264.7 cells without cytotoxicity.
- Subjects :
- Pharmacology
chemistry.chemical_classification
010405 organic chemistry
medicine.drug_class
Stereochemistry
Chemical structure
Plant Science
General Medicine
01 natural sciences
Anti-inflammatory
0104 chemical sciences
Nitric oxide
010404 medicinal & biomolecular chemistry
chemistry.chemical_compound
Complementary and alternative medicine
chemistry
Triterpene
Drug Discovery
medicine
Camellia sinensis
Medicinal plants
Chemical composition
Oleanane
Subjects
Details
- ISSN :
- 15559475 and 1934578X
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Natural Product Communications
- Accession number :
- edsair.doi.dedup.....ad24b3a264b6b8e1a3ceee59a84724dd