Back to Search
Start Over
Volatile oil from striped African pepper (Xylopia parviflora, Annonaceae) possesses notable chemopreventive, anti-inflammatory and antimicrobial potential
- Source :
- Food Chemistry. 149:183-189
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- Fruits of Xylopia parviflora, well known as striped African pepper, are sold in the Cameroonian markets as a flavouring ingredient to make traditional soups. The essential oil hydrodistilled from fruits was analysed for in vitro biological activities, namely cytotoxic, anti-inflammatory, antimicrobial and antioxidant, by MTT, nitric oxide inhibitory assay, agar disc diffusion method, and DPPH and ABTS assays. The essential oil composition, analysed by GC and GC-MS, was dominated by monoterpene hydrocarbons (50.0%) responsible for the pepper odour, such as β-pinene (34.0%) and α-pinene (10.3%). The oil induced a strong inhibitory effect on tumour cells MDA-MB 231 and HCT116, with inhibition values close to those of cisplatin. A dose-dependent decrease in NO production was noted in RAW 264.7 macrophages treated with the oil, revealing a promising anti-inflammatory potential. The essential oil showed a measurable antimicrobial activity against all the species tested, while the radical scavenging activity was low.
- Subjects :
- DPPH
medicine.drug_class
Anti-Inflammatory Agents
Protective Agents
Antioxidants
Anti-inflammatory
Analytical Chemistry
law.invention
Mice
chemistry.chemical_compound
Ingredient
Anti-Infective Agents
law
Cell Line, Tumor
Neoplasms
Pepper
Botany
Oils, Volatile
medicine
Animals
Humans
Essential oil
Cell Proliferation
ABTS
Bacteria
biology
Traditional medicine
Macrophages
Fungi
food and beverages
General Medicine
biology.organism_classification
Antimicrobial
Xylopia
chemistry
Annonaceae
Food Science
Subjects
Details
- ISSN :
- 03088146
- Volume :
- 149
- Database :
- OpenAIRE
- Journal :
- Food Chemistry
- Accession number :
- edsair.doi.dedup.....9db250781ffda7e4a17ade0c6b80754c