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A rapid ATR-FTIR spectroscopic method for detection of sibutramine adulteration in tea and coffee based on hierarchical cluster and principal component analyses
- Source :
- Food Chemistry. 229:517-526
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Sibutramine may be illicitly included in herbal slimming foods and supplements marketed as "100% natural" to enhance weight loss. Considering public health and legal regulations, there is an urgent need for effective, rapid and reliable techniques to detect sibutramine in dietetic herbal foods, teas and dietary supplements. This research comprehensively explored, for the first time, detection of sibutramine in green tea, green coffee and mixed herbal tea using ATR-FTIR spectroscopic technique combined with chemometrics. Hierarchical cluster analysis and PCA principle component analysis techniques were employed in spectral range (2746-2656cm-1) for classification and discrimination through Euclidian distance and Ward's algorithm. Unadulterated and adulterated samples were classified and discriminated with respect to their sibutramine contents with perfect accuracy without any false prediction. The results suggest that existence of the active substance could be successfully determined at the levels in the range of 0.375-12mg in totally 1.75g of green tea, green coffee and mixed herbal tea by using FTIR-ATR technique combined with chemometrics.
- Subjects :
- Food Contamination
Coffee
complex mixtures
01 natural sciences
Analytical Chemistry
Chemometrics
Herbal tea
0404 agricultural biotechnology
Spectroscopy, Fourier Transform Infrared
medicine
Cluster Analysis
Food science
Green coffee
Principal Component Analysis
Tea
010401 analytical chemistry
food and beverages
04 agricultural and veterinary sciences
General Medicine
NUTRITION&DIETETICS
Green tea
040401 food science
0104 chemical sciences
Hierarchical clustering
Principal component analysis
Cyclobutanes
Food Science
Sibutramine
medicine.drug
Subjects
Details
- ISSN :
- 03088146
- Volume :
- 229
- Database :
- OpenAIRE
- Journal :
- Food Chemistry
- Accession number :
- edsair.doi.dedup.....86653439d7c59b1171561f3e044e8aca