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Evaluation of antioxidant and immune activity of Phellinus ribis glucan in mice
- Source :
- Food Chemistry. 115:581-584
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- The potential protective effects of Phellinus ribis glucan (PRG) administration against immune injury due to free radical formation were evaluated in mice. The results showed that glucan administration significantly increased thymus and spleen indices, spleen lymphocyte proliferation and NK cells activity, as well as CD8 T cell numbers, and decreased CD4+/CD8+. In accordance with a previous study, glucan administration significantly enhanced plasma glutathione peroxidase, superoxide dismutases activity and reduced plasma thiobarbituric acid reactive species level. In conclusion, our results indicate that glucan administration improve immune function by its free radicals scavenging activity and reducing oxidative stress in mice.
- Subjects :
- chemistry.chemical_classification
Antioxidant
GPX3
biology
Chemistry
Thiobarbituric acid
medicine.medical_treatment
General Medicine
Lymphocyte proliferation
Pharmacology
medicine.disease_cause
Analytical Chemistry
Superoxide dismutase
chemistry.chemical_compound
Immune system
Biochemistry
medicine
biology.protein
Oxidative stress
Food Science
Glucan
Subjects
Details
- ISSN :
- 03088146
- Volume :
- 115
- Database :
- OpenAIRE
- Journal :
- Food Chemistry
- Accession number :
- edsair.doi...........87342afa478e54a76c681ef19e6e2d2b