Phenobarbital-mediated increase in ring- and N-hydroxylation of the carcinogen N-2-fluorenylacetamide, and decrease in amounts bound to liver deoxyribonucleic acid.

Subjects

Subjects :

Acetamides metabolism
Animals
Body Weight drug effects
Carbon Isotopes
Carbon Monoxide pharmacology
Carcinogens urine
Chromatography, Paper
Cytochrome P-450 Enzyme System analysis
Hydroxylation
In Vitro Techniques
Microsomes, Liver drug effects
Microsomes, Liver metabolism
Organ Size
Phenobarbital administration & dosage
Proteins analysis
Rats
DNA metabolism
Fluorenes metabolism
Liver metabolism
Phenobarbital pharmacology

Details

Language :

English

ISSN :

0006-2952

Volume :

21

Issue :

15

Database :

MEDLINE

Journal :

Biochemical pharmacology

Publication Type :

Academic Journal

Accession number :

4645881

Full Text :

https://doi.org/10.1016/0006-2952(72)90158-x