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Phenolic content, antioxidant and anti-inflammatory activities of Tunisian Diplotaxis simplex (Brassicaceae).
- Source :
-
Natural product research [Nat Prod Res] 2015; Vol. 29 (12), pp. 1189-91. Date of Electronic Publication: 2015 Jan 21. - Publication Year :
- 2015
-
Abstract
- This study investigates the polyphenol content of Diplotaxis simplex extract and the biological activities of the main organ. The analysed extracts showed that polyphenol contents varied considerably as a function of organs. Furthermore, novel biological activities of this species were assessed. Flower extracts exhibit a potent in vitro antioxidant capacity using oxygen radical absorbance capacity and displayed a strong anti-inflammatory activity, inhibiting nitric oxide release, by 79.3% at 160 μg/mL. Our findings suggested that the Diplotaxis flower is a valuable source of antioxidants and anti-inflammatory agents.
- Subjects :
- Animals
Cell Line
Flavonoids chemistry
Flowers chemistry
Macrophages drug effects
Mice
Nitric Oxide chemistry
Plant Extracts pharmacology
Proanthocyanidins chemistry
Anti-Inflammatory Agents pharmacology
Antioxidants pharmacology
Brassicaceae chemistry
Phenols chemistry
Plant Extracts chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 29
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 25604628
- Full Text :
- https://doi.org/10.1080/14786419.2014.983505