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The effect of tea consumption on oxidative stress in smokers and nonsmokers.
- Source :
-
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) [Proc Soc Exp Biol Med] 1999 Apr; Vol. 220 (4), pp. 249-54. - Publication Year :
- 1999
-
Abstract
- While the anticarcinogenic effects of tea in animal models have been reported by several groups, human epidemiological studies examining tea consumption and cancer prevention have produced equivocal results. The beneficial properties of tea to human health may be related to the antioxidant properties of tea components. However, little evidence has been provided that tea consumption can either increase the antioxidant capacity or decrease oxidative stress in humans. In the present study, the effects of tea treatment (green tea) on biomarkers of oxidative stress were investigated in smokers and nonsmokers in two volunteer study groups (one in China and the other in United States). Green tea consumption in both study groups decreased oxidative DNA damage (8-OHdG in white blood cells and urine), lipid peroxidation (MDA in urine), and free radical generation (2, 3-DHBA in urine) in smokers. Nonsmokers (US study group) also exhibited a decrease in overall oxidative stress.
- Subjects :
- 3,4-Methylenedioxyamphetamine blood
3,4-Methylenedioxyamphetamine urine
8-Hydroxy-2'-Deoxyguanosine
Adult
Antioxidants pharmacology
Chromatography, High Pressure Liquid
Deoxyguanosine analogs & derivatives
Deoxyguanosine urine
Female
Humans
Hydroxybenzoates urine
Leukocytes chemistry
Lipid Peroxidation drug effects
Male
Middle Aged
Oxidative Stress drug effects
Plant Extracts pharmacology
Smoking blood
Smoking urine
Tea
Subjects
Details
- Language :
- English
- ISSN :
- 0037-9727
- Volume :
- 220
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 10202398
- Full Text :
- https://doi.org/10.1046/j.1525-1373.1999.d01-43.x