A glutamate residue at the C terminus regulates activity of inward rectifier K[sup +] channels: Implication for Andersen's syndrome.

Authors :: Lei Chen
Kawano, Takeharu
Bajic, Sibinka
Kaziro, Yoshito
Itoh, Hiroshi
Art, Jonathan J.
Nakajima, Yasuko
Nakajima, Shigehiro
Source :: Proceedings of the National Academy of Sciences of the United States of America. 6/11/2002, Vol. 99 Issue 12, p8430. 6p. 1 Black and White Photograph, 1 Diagram, 1 Chart, 10 Graphs.
Publication Year :: 2002
Abstract: Examines the role of glutamate residue of G protein-coupled inward rectifiers (GIRK) in the regulation of potassium channels. Localization of GIRK2 in the domain of C terminus; Mechanisms of GIRK and inward rectifiers trafficking to cell membranes; Interaction between GIRK2 and G protein ΒΓ.

Language :: English
ISSN :: 00278424
Volume :: 99
Issue :: 12
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 7135515
Full Text :: https://doi.org/10.1073/pnas.122682899

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