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Sensitisation to molecular components of mites in atopic dermatitis patients.

Authors :
Čelakovská, J.
Čermákova, E.
Vaňková, R.
Boudkova, P.
Andrýs, C.
Krejsek, J.
Source :
Food & Agricultural Immunology. Dec2022, Vol. 33 Issue 1, p588-603. 16p.
Publication Year :
2022

Abstract

Background and aim: To analyse the sensitisation profile to molecular components of mites allergens with the use of ALEX2 Allergy Explorer test in Atopic dermatitis (AD) patients. Method: The complete dermatological and allergological examination including the examination of the sensitisation to molecular components with ALEX2 Allergy Explorer testing was performed. For the statistical analysis, we used Fisher's Exact. Results and conclusion: The sensitisation to mites increases with AD severity. The central role in atopic march may play the molecular component Der f 2 and Der p 23. The results of our study confirm the important role of Der p 5 and Der p 7 in subgroup of patients suffering from bronchial asthma. The specific immunotherapy should focus on the components of NPC2 family and Der p 23 in AD patients. Our results may be helpful in planning hyposensitisation, treatment and immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09540105
Volume :
33
Issue :
1
Database :
Academic Search Index
Journal :
Food & Agricultural Immunology
Publication Type :
Academic Journal
Accession number :
160508481
Full Text :
https://doi.org/10.1080/09540105.2022.2100323