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Anti-diabetic polysaccharides from natural sources: A review.
- Source :
-
Carbohydrate Polymers . Sep2016, Vol. 148, p86-97. 12p. - Publication Year :
- 2016
-
Abstract
- Diabetes mellitus (DM) is a metabolic disease attracted worldwide concerns, which severely impairs peoples’ quality of life and is attributed to several life-threatening complications, including atherosclerosis, nephropathy and retinopathy. The current therapies for DM include mainly oral anti-diabetic drugs and insulin. However, continuous use of these causes insulin resistance and side-effects, and the demand of effective, nontoxic and affordable drugs for DM patients is eager. Several previous studies have shown that non-toxic biological macromolecules, mainly polysaccharides, possess prominent efficacies on DM. Based on these encouraging observations, a great deal of efforts have been focused on discovering anti-diabetic polysaccharides for the development of effective therapeutics for DM. This review focuses on the advancements in the anti-diabetic efficacy of various natural polysaccharides and polysaccharide complexes from 2010 to 2015. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01448617
- Volume :
- 148
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Polymers
- Publication Type :
- Academic Journal
- Accession number :
- 115367908
- Full Text :
- https://doi.org/10.1016/j.carbpol.2016.02.060