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Background. Teratomas are neoplasms that arise from pluripotent germ cells, derived from two or more layers of germ cells. They are classified as mature tumors (cystic or solid), which contain well-differentiated tissues, or as immature tumors, which contain immature and embryonic structures. Its most frequent location is the female and male gonads; the mesenteric location is rare and approximately 40 cases have been described in the world literature. Within the diagnostic and therapeutic approach, computed tomography and magnetic resonance imaging are used to characterize the lesion, assess intra-abdominal extension and the relationship with other structures. The diagnosis must be confirmed by histopathological examination. Clinical case. A 56-year-old female patient with a history of infiltrating ductal carcinoma of the left breast in remission. In follow-up studies, incidental abdominal tomography finding of an abdominopelvic lesion dependent on the mesentery at the level of the mesogastrium, smooth contours with fat-liquid level. Extension studies with negative tumor markers. Results: Due to high clinical and imaging suspicion of teratoma, the patient was taken to resection of the lesion. Histopathological examination confirmed the diagnosis of mature cystic teratoma of the mesentery. Conclusion: Mesenteric teratoma is a rare clinical entity and is considered one of the differential diagnoses of an abdominal mass with a compressive effect. Diagnosis is mainly based on clinical examination and imaging findings. Early surgical excision is the mainstay of treatment; laparoscopic or open approach depends on the clinical characteristics and the experience of the surgeon. [ABSTRACT FROM AUTHOR]

Introducción. Los teratomas son neoplasias que surgen a partir de células germinales pluripotenciales y derivan de dos o más capas de células. Se clasifican en tumores maduros, que contienen tejidos bien diferenciados, o inmaduros, que contienen estructuras inmaduras y embrionarias. Su localización más frecuente son las gónadas; la ubicación mesentérica es infrecuente y se han descrito aproximadamente 40 casos en la literatura mundial. Dentro del abordaje diagnóstico y terapéutico, se emplea la tomografía computarizada y la resonancia magnética nuclear para caracterizar la lesión, evaluar la extensión intraabdominal y la relación con otras estructuras. El diagnóstico debe confirmarse mediante el examen histopatológico. Caso clínico. Paciente femenina de 56 años, con antecedente de carcinoma ductal infiltrante de mama izquierda en remisión, en estudios de seguimiento con hallazgo incidental en tomografía de abdomen de lesión abdominopélvica dependiente del mesenterio, contornos lisos y nivel grasa-líquido. Estudios de extensión con marcadores tumorales negativos. Resultados. Por la alta sospecha clínica e imagenológica de teratoma, fue llevada a resección quirúrgica de la lesión. El examen histopatológico confirmó el diagnóstico de teratoma quístico maduro del mesenterio. Conclusión. El teratoma mesentérico es una entidad clínica rara, que debe ser considerado como uno de los diagnósticos diferenciales de una masa abdominal con efecto compresivo. El diagnóstico se basa principalmente en el examen clínico y los hallazgos imagenológicos. La escisión quirúrgica temprana es el pilar del tratamiento; el abordaje laparoscópico o abierto depende de las características clínicas y la experiencia del cirujano.

Background: Mature teratomas belong to the group of germ line ovarian tumors; they generally have benign behavior. Malignant transformation occurs in 0.2% to 1% of tumors. The objective is to show the results of peritonectomy with HIPEC in the treatment of a mature teratoma with malignant differentiation with signet ring cells. Clinical case: 43-year-old woman diagnosed with mature malignant teratoma with signet ring cells. It was performed optimal primary cytoreduction surgery, total hysterectomy, bilateral salpingo-oophorectomy, peritonectomy, appendectomy, cholecystectomy and splenectomy adding intraoperative hyperthermic chemotherapy (HIPEC). Conclusions: Malignant transformation of a mature teratoma of the ovary is a rare event, but not exceptional. HIPEC was used after optimal cytoreduction, with good results, since the patient is in a disease-free period of 36 months. It is necessary to report cases in order to compare different types of treatment to improve oncological results. [ABSTRACT FROM AUTHOR]

We describe the unusual case of a female patient with a history of two mature teratomas non-correlated in terms of location and occurrence. A 12-year-old girl presented at our consultation as a result of a growing tumor in the hypogastric region, with no further clinical signs. She had undergone surgery neonatally due to a mature cystic sacrococcygeal teratoma, which was fully removed. No clinical sequelae were noted and no additional treatment was required over a 10-year follow-up. Radiological examination showed a large 20 x 12 x 18 cm cystic mass extending from the pelvic region to the lower hemiabdomen, associated with two similar small formations adjacent to the right ovary. Tumor markers were negative, and a laparoscopic right salpingoophorectomy was carried out, with an excellent postoperative progression. Pathological examination revealed it was, again, a mature cystic teratoma. The genetic study ruled out causation in this respect. [ABSTRACT FROM AUTHOR]

Paciente femenina de 48 años que acude a valoración por dolor y sensación de masa de crecimiento progresivo en cuadrante inferior derecho del abdomen, con historia de un año de molestias con determinados ejercicios que involucran el uso del músculo psoas derecho. Al examen físico se encuentra masa palpable en flanco derecho, con dolor a la palpación profunda, sin signos de irritación peritoneal.

Introducción. Fetus in fetu es una rara entidad congénita en la cual se presenta un gemelo monocigótico que en la mayoría de los casos está incorporado en el abdomen del hermano. La presentación más frecuente es una masa retroperitoneal. La diferenciación diagnóstica entre fetus in fetu y teratoma es discutida. El objetivo de este trabajo es describir el caso de dos pacientes con fetus in fetu, mediante una revisión reducida de la literatura en sus hipótesis etiológicas y métodos diagnósticos. Reporte de casos. Se presentan 2 casos, el primer caso es un lactante menor con distensión abdominal persistente, en quien se palpó masa abdominal. El segundo caso es un recién nacido con diagnóstico prenatal de masa abdominal. Ambos casos presentan imágenes radiológicas que evidencian masa abdominal compatible con fetus in fetu, razón por la cual posteriormente fueron intervenidos quirúrgicamente para resección de la masa. Discusión. Es importante tener presente esta patología como diagnóstico diferencial de masa abdominal en los pacientes infantes, ya que el poder diferenciarlo de un teratoma maduro nos indicaría que se trata de una alteración del desarrollo embriológico y no de una patología tumoral. Para esto, son necesarios métodos imagenológicos y en algunos casos pruebas cromosómicas o histopatológicas, con el fin de esclarecer el diagnóstico del fetus in fetu. Conclusión. El fetus in fetu es una patología rara con pocos casos diagnosticados prenatalmente, la cual se diagnostica principalmente en la infancia. Las imágenes radiológicas y en algunos casos las pruebas cromosómicas o histopatológicas, son de gran importancia para el diagnóstico definitivo. Cómo citar. Lubinus F, Zuñiga-Hadechni E, López L, Rueda-Hernández, CA. Fetus in fetu, presentación de dos casos: diagnóstico diferencial y revisión de la literatura. MedUNAB. 2020;23(3):464-470. doi: doi.org/10.29375/01237047.3685 Introduction. Fetus in fetu is a rare congenital condition that has been defined as the presence of one monozygotic twin, in most cases, in the sibling’s abdomen. It is most frequently present as a retroperitoneal mass. The diagnostic difference between fetus in fetu and teratoma is discussed. This work’s objective is to describe the case of two patients with fetus in fetu through a reduced literature review in terms of etiologic hypotheses and diagnostic methods. Case Reports. Two cases are presented. The first case is that of an infant with persistent abdominal distension, in whom an abdominal mass was found by palpating. The second case is that of a newborn baby with a prenatal abdominal mass diagnosis. Both cases present X-ray images that demonstrate an abdominal mass compatible with fetus in fetu, reason why the patients were subsequently surgically intervened to remove the mass. Discussion. It is important to keep this pathology in mind as a differential diagnosis of abdominal masses in infant patients, since being able to differentiate it from a mature teratoma would indicate that the mass is an embryonic development alteration, not a tumor pathology. Imaging methods and, in some cases, chromosome or histopathological analyses, are necessary for this, in order to clarify the diagnosis of fetus in fetu. Conclusion. Fetus in fetu is a rare pathology with few cases diagnoses prenatally. It is mainly diagnosed during infancy. X-ray images and, in some cases, chromosome or histopathological analyses, are greatly important for definitive diagnoses. Cómo citar. Lubinus F, Zuñiga-Hadechni E, López L, Rueda-Hernández, CA. Fetus in fetu, presentación de dos casos: diagnóstico diferencial y revisión de la literatura. MedUNAB. 2020;23(3):464-470. doi: doi.org/10.29375/01237047.3685 Introdução. Fetus in fetu é uma entidade congénita rara em que existe um gémeo monozigótico que, na maioria dos casos, está incorporado no abdómen do irmão. A apresentação mais comum é uma massa retroperitoneal. A diferenciação diagnóstica entre fetus in fetu e teratoma é discutida. O objetivo deste trabalho é descrever o caso de dois pacientes com fetus in fetu, por meio de uma revisão reduzida da literatura sobre as suas hipóteses etiológicas e métodos de diagnóstico. Relato de casos. Dois casos são apresentados, o primeiro, é um bebê menor com distensão abdominal persistente, no qual foi sentida uma massa abdominal. O segundo caso é um recém-nascido com diagnóstico pré-natal de massa abdominal. Ambos os casos apresentam imagens radiológicas mostrando massa abdominal compatível com fetus in fetu, razão pela qual foram posteriormente operados para ressecção da massa. Discussão. É importante considerar esta patologia como diagnóstico diferencial da massa abdominal em pacientes infantis, uma vez que ser capaz de diferenciá-la de um teratoma maduro indicaria que se trata de uma alteração no desenvolvimento embriológico e não de uma patologia tumoral. Para isso, são necessários métodos de imagem e em alguns casos testes cromossômicos ou histopatológicos, a fim de esclarecer o diagnóstico do fetus in fetu. Conclusão. Fetus in fetu é uma patologia rara que é diagnosticado principalmente na infância, com poucos casos diagnosticados no pré-natal. As imagens radiológicas e, em alguns casos, os testes cromossômicos ou histopatológicos são de grande importância para o diagnóstico definitivo. Cómo citar. Lubinus F, Zuñiga-Hadechni E, López L, Rueda-Hernández, CA. Fetus in fetu, presentación de dos casos: diagnóstico diferencial y revisión de la literatura. MedUNAB. 2020;23(3):464-470. doi: doi.org/10.29375/01237047.3685

Testicular tumors are rare in children under 15 years of age and represent 2 to 4% of all childhood cancers, cryptorchidism is the main risk factor for the later development of testicular germ cell tumors. 5-year-old preschool boy, with a history of left cryptorchidism without treatment, for the last year he has presented a progressive increase in volume in the left inguinal which extended to the left scrotal region, of petrified consistency, not painful on palpation, without adenomegaly, negative tumor markers, testicular ultrasound reported: left cystic tumor, lower abdomen tomography reported: left testicular tumor. A left radical orchiectomy and right orchidopexy were performed, with satisfactory evolution. The diagnosis of mature cystic teratoma is confirmed by biopsy and immunohistochemistry. Early diagnosis and management of cryptorchidism is important to avoid future neoplasms. [ABSTRACT FROM AUTHOR]

BACKGROUND: Germ cell tumors usually manifest as 90% unclassifiable intratubular germ cell neoplasia, with a peak in the fourth decade of life, and most often affect Caucasian individuals. CLINICAL CASE: A 26-year-old man with a testicular tumor treated with radical orchiectomy and chemotherapy. Histology showed the characteristics of a mixed germ cell tumor with mature teratoma components, polyembrioma with embryonal carcinoma component and endodermal sinus tumor. CONCLUSIONS: Polyembrioma is a distinctive component of germ cell neoplasms. Some authors consider this component the most immature form of teratoma and others think that it is a distinctive pattern within mixed germ cell tumors. [ABSTRACT FROM AUTHOR]

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction. Fetus in fetu is a rare congenital condition that has been defined as the presence of one monozygotic twin, in most cases, in the sibling's abdomen. It is most frequently present as a retroperitoneal mass. The diagnostic difference between fetus in fetu and teratoma is discussed. This work's objective is to describe the case of two patients with fetus in fetu through a reduced literature review in terms of etiologic hypotheses and diagnostic methods. Case Reports. Two cases are presented. The first case is that of an infant with persistent abdominal distension, in whom an abdominal mass was found by palpating. The second case is that of a newborn baby with a prenatal abdominal mass diagnosis. Both cases present X-ray images that demonstrate an abdominal mass compatible with fetus in fetu, reason why the patients were subsequently surgically intervened to remove the mass. Discussion. It is important to keep this pathology in mind as a differential diagnosis of abdominal masses in infant patients, since being able to differentiate it from a mature teratoma would indicate that the mass is an embryonic development alteration, not a tumor pathology. Imaging methods and, in some cases, chromosome or histopathological analyses, are necessary for this, in order to clarify the diagnosis of fetus in fetu. Conclusion. Fetus in fetu is a rare pathology with few cases diagnoses prenatally. It is mainly diagnosed during infancy. X-ray images and, in some cases, chromosome or histopathological analyses, are greatly important for definitive diagnoses. [ABSTRACT FROM AUTHOR]

Copyright of Dilemas Contemporáneos: Educación, Política y Valores is the property of Dilemas Contemporaneos: Educacion, Politica y Valores and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Revista Medicina is the property of Revista Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ginecología y Obstetricia de México is the property of Federacion Mexicana de Ginecologia y Obstetricia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Dermoid cysts or mature cystic teratomas are mesenchymal neoplasms most commonly found in the ovaries, but which may occur in any location along the pathways of ectodermal cell migration. They are rarely seen in the pancreas, where they show a slight preference for the pancreatic head. We report a case of dermoid cyst of the pancreas in a 69-year-old male patient, discussing the epidemiology, clinical presentation, diagnosis and treatment of this neoplasm. Since preoperative diagnosis is difficult, given its rarity in this site, it is usually diagnosed by histopathology of the specimen.

Objetivos: Definir los criterios de selección para la vía de abordaje por laparotomía versus laparoscopia. Método: Estudio retrospectivo de los casos de teratoma maduro manejados entre los años 1991 y 2003. Resultados: Los teratomas maduros corresponden al 14% de los tumores ováricos. La edad de presentación correspondió mayoritariamente a mujeres en edad reproductiva (67%). Trece casos se presentaron en embarazadas, 11 durante la cesárea. La presentación más frecuente fue como hallazgo clínico o a la ultra-sonografía pelviana durante el estudio por otra patología. En la mitad de los casos el abordaje fue por vía la-paroscópica (LPX). En tumores mayores de 9 cm, se privilegió la laparotomía (LPE) (pObjectives: To define selection criteria for surgical approach, laparoscopy or laparotomy. Methods: A retrospectivo analysis of cases diagnosed and treated between 1991 and 2003 was conducted. All clinical charts of treated cases were reviewed. Results: Mature teratomas represented about 14% of ovarían tumors. The age of presentation was mainly at reproductive age (67%). Thirteen cases were diagnosed during pregnancy and eleven of them were found at the time of a cesarean section. The most frequent form of clinical presentation was as an incidental finding during clinical examination or pelvic ultrasound made while studying by other pathologies. In about a half of cases the chosen surgical approach was laparoscopy (LPX). In tumors biggerthan 9 cm, an open approach by laparotomy (LPE) was preferred (p

Copyright of Revista Chilena de Obstetricia y Ginecología is the property of Revista Chilena de Obstetricia y Ginecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Médica Clínica Las Condes is the property of Editorial Sanchez y Barcelo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Chilena de Obstetricia y Ginecología is the property of Revista Chilena de Obstetricia y Ginecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)