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2 results on '"taraxerene"'

1. Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata

Author

Qing-Wei Tan, Ming-An Ouyang, Qi-Jian Chen, and Zu-Jian Wu

Subjects
Davidia involucrata, Nyssaceae, taraxerene, triterpenoid, Organic chemistry, QD241-441
Abstract

Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404.

Published
2014
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2. Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata

Author

Qi-Jian Chen, Ming-An Ouyang, Qing-Wei Tan, and Zujian Wu

Subjects
taraxerene, Stereochemistry, Pharmaceutical Science, Cornaceae, Article, Analytical Chemistry, lcsh:QD241-441, Terpene, Davidia involucrata, Triterpenoid, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, Humans, Physical and Theoretical Chemistry, biology, Molecular Structure, Chemistry, Spectrum Analysis, Organic Chemistry, biology.organism_classification, Antineoplastic Agents, Phytogenic, Triterpenes, Chemistry (miscellaneous), MCF-7 Cells, Molecular Medicine, Nyssaceae, triterpenoid
Abstract

Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404.

Published
2014

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