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Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata

Authors :
Qing-Wei Tan
Ming-An Ouyang
Qi-Jian Chen
Zu-Jian Wu
Source :
Molecules, Vol 19, Iss 11, Pp 17619-17631 (2014)
Publication Year :
2014
Publisher :
MDPI AG, 2014.

Abstract

Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404.

Details

Language :
English
ISSN :
14203049
Volume :
19
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.711e622496694a3da1344dc1bfcf053c
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules191117619