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The article discusses the increasing importance of nanochemistry in research and everyday life, leading to its inclusion in the curricula of several German states. The development of the student laboratory setting Nan_OS aims to provide high school students with insights into the properties, applications, opportunities, and risks of nanochemistry. Three innovative experiments are detailed, focusing on the synthesis of nanoparticles, their application in environmental technology, and the creation of carbon quantum dots. The experiments are designed to enhance students' competencies in nanochemistry and promote scientific literacy. The article also provides biographical information about the authors involved in developing the student laboratory setting. [Extracted from the article]

This article explores the field of nanomedicine and its potential applications in targeted drug delivery. It discusses the concept of "nanocarriers" that can transport drugs to specific organs and infected tissues, minimizing side effects. The article presents two experimental series that demonstrate the synthesis and loading of nanoparticles using polymers and various cargos. The experiments investigate the behavior of the nanoparticles in response to changes in pH, showing promising results for targeted drug delivery. The article highlights the educational opportunities and interdisciplinary connections that can be made through the teaching of nanomedicine in chemistry, biology, and physics classes. [Extracted from the article]

Methylene blue liposomes (MB-LPs) intended for photodynamic therapy (PDT) of ovarian cancer were formulated with a negatively charged nucleolipid and phosphatidylcholine using the lipidic film technique followed by an extrusion step. MB-LPs were characterized using dynamic light scattering (DLS), zeta potential (ZP), transmission electron microscopy (TEM), colloidal stability, Fourier-transform infra-red spectroscopy (FT-IR), UV-Visible spectroscopy and cellular studies. MB-LPs were spherical nano-objects with sizes obtained by DLS and TEM between 120 and 130 nm. MB-LPs showed a PDI near 0.10, a negative zeta potential near -42 mV and an encapsulation efficiency around 57 %. Characteristic peaks from ionic interactions of nucleolipids encapsulation of methylene blue were confirmed by FT-IR. Colloidal stability of MB-LPs was slightly affected in complex ionic media, sizes, PDI and ZP remained stable for 4 weeks at all storage temperature tested, allowing a potential use for in vitro and in vivo assays. The use of MB-LPs allowed slightly higher PDT activity based on the production of ROS against SKOV-3 ovarian cancer as compared to MB alone, a reduction of MB dark toxicity and a better protection against oxidation-reduction reactions.

Copyright of Výživa a Potraviny is the property of Spolecnost pro Vyzivu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Text předkládá výsledky kvalitativní studie, která byla zaměřena na problematiku využití nanomateriálů v mimořádné situaci spojené s pandemií covid-19 na příkladu iniciativy Roušky s TULkou. Ta během několika týdnů iniciovala výrobu vysoce účinných nanovlákenných filtrů s využitím originální technologie (AC Electrospinning) v průmyslovém měřítku. Cílem výzkumu bylo vedle popisu regionální zkušenosti, analyzovat hodnotové výzvy, konflikty a etická dilemata v mimořádné situaci. Hlavními teoretickými východisky studie je turnerovské pojetí liminality, communitas a antistruktury a Stennerův koncept liminálních prostorů. Výsledky výzkumu ukazují, že pandemická situace přispěla k odkrytí nečekaného potenciálu nové technologie, že při realizaci celé aktivity kromě know-how a technického zázemí univerzity sehrál roli především sociální kapitál, a především odkrývají potenciál, který vycházel z antistrukturního charakteru iniciativy a dočasného překročení hierarchicky nastavených univerzitních struktur.

Z pozice filosofie vědy a techniky se nejprve zabýváme otázkou, co znamenají nanotechnologie v rámci evoluce technologií. Jejich mimořádný význam primárně vidíme v tom, že jsou technologiemi samotného života. Dále vysvětlujeme, že nanoúroveň je doménou, kde se kříží zákonitosti kvantové a klasické newtonovské fyziky. Z této pozice vycházíme při hledání odpovědi na otázku, za jakých podmínek mění zmenšování věci také jejich funkční podstatu. Na příkladu debaty Drexler vs. Smalley demonstrujeme paradigmatickou nesouměřitelnost obou perspektiv a fyzikálně-chemické a inženýrské limity nanotechnologií. Zvažujeme, nakolik jsou reálná nebezpečí a etické implikace vycházející z Drexlerových úvah, ať už se jedná o tzv. „grey goo“ problém nebo molekulární výrobu. Jako závažnější hodnotíme vybrané problémy spojené se syntetickou biologií. Text zakončujeme úvahou, že pro lidskou civilizaci by mělo být existenční výzvou přemýšlet o možnostech nanotechnologií k rozvíjení života.

Copyright of MESO is the property of Zadruzna Stampa D.D. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

L’hémodialyse à domicile doit rester une technique parmi tant d’autres pour traiter l’insuffisance rénale terminale. Pour cela tout doit être mis en place pour que les patients puissent avoir le choix, aidés par leur équipe soignante. La gestion de l’accessibilité à un traitement d’eau à domicile reste encore de nos jours difficile malgré les progrès notables lors des dernières décennies. Le développement de l’HDQD sans avoir à installer un traitement d’eau au domicile des patients est un progrès notable qui a donné un élan nécessaire au développement du traitement du patient au domicile. Les défis restent grands malgré tout, notamment pour le développement de la dialyse à sorbants qui devrait revoir le jour avec l’aide des nanotechnologies cela aidera à augmenter le nombre de patients, mais aussi à avoir une attitude éco responsable, en diminuant les quantités d’eau utilisées et les déchets générés par ce type de traitement.

Die Verwendung von Nanopartikeln und nanostrukturierten Elektroden ist in der Elektrokatalyse weit verbreitet. Diese nanometrischen Systeme enthalten je nach Geometrie Elemente des Nanoconfinements in unterschiedlichem Ausmaß, was sich viel stärker auf die Aktivität und Selektivität auswirken kann, als oft angenommen wird. In diesem Aufsatz identifizieren wir zunächst die Systeme, die unterschiedliche Grade von Nanoconfinement enthalten, und zeigen, wie sie die Aktivität und Selektivität elektrokatalytischer Reaktionen beeinflussen können. Anschließend wird ein grundlegendes Verständnis der Auswirkungen des Nanoconfinements auf die Elektrochemie und Elektrokatalyse vermittelt, das dank der Entwicklung neuer, atomar präziser Herstellungs‐ und Fertigungstechniken und Fortschritten bei der theoretischen Modellierung allmählich erschlossen wird. Diese Übersicht soll dabei helfen, die Nanostrukturierung nicht nur zur Vergrößerung der Oberfläche zu nutzen, sondern auch die thermodynamisch bedingten Skalierungsbeziehungen in der Elektrokatalyse zu durchbrechen. [ABSTRACT FROM AUTHOR]

The text presents the results of a qualitative study focused on the issue of using nanomaterials in the extraordinary circumstances linked to the COVID-19 pandemic, particularly referring to the "Roušky s TULkou" initiative. Within several weeks, this initiative managed to launch the production of highly efficient nanofiber filters using the original AC Electrospinning technology on an industrial scale. The goal of the research was to analyse both the regional experience and the value-based challenges, conflicts and ethical dilemmas posed by an emergency situation. The theoretical starting points of the research were the Turnerian understanding of liminality, communitas and antistructure and Stenner's concept of liminal spaces. The results of the research show that the pandemic situation contributed to the emergence of an unexpected potential of the new technology and that the realisation of the activity was influenced not only by know-how and the university's technical facilities, but particularly by social capital, thus uncovering the potential of the antistructural character of the initiative and the temporary suspension of hierarchically established university structures. [ABSTRACT FROM AUTHOR]

From the perspective of philosophy of science and technologies, we firstly attend to the issue of the role of nanotechnologies within the evolution of technologies. We recognize their utmost importance in the respect that they are technologies of life itself. We further explain that the nano-level is the domain of intersection of the rules of quantum physics and traditional Newtonian physics. This is our starting point from which we discuss the issue of conditions under which minimizing things also changes their functional essence. We use the example of the Drexler vs. Smalley debate to demonstrate the paradigmatic incomparability of the two perspectives and the physical-chemical and engineering-related limits of nanotechnologies. We discuss to what extent are the dangers and ethical implications emerging from Drexler's contemplations real, be it what he calls the "grey goo" problem or the issues of molecular production. We regard certain problems linked to synthetic biology as more serious. We conclude our text with the consideration that the human civilization should think of the possibilities of nanotechnologies in the development of life as an existential challenge. [ABSTRACT FROM AUTHOR]

DNA‐Nanotechnologie und Fortschritte in der DNA‐Origami‐Technik haben das einfache Design und die Synthese komplexer und funktioneller Nanostrukturen ermöglicht. Jedoch sind molekulare Geräte aufgrund des hohen Anteils von Oberflächenatomen und der komplexen Einsatzbedingungen im Nanomaßstab anfällig für eine schnelle funktionelle und strukturelle Degradierung. Neben Stabilisierungsmechanismen sind Ansätze zur Selbstreparatur funktioneller molekularer Geräte wünschenswert. Hier nutzen wir die selbst‐assemblierenden und rekonfigurierbaren Eigenschaften von DNA‐Origami‐Nanostrukturen für die Selbstreparatur von photoinduzierten und enzymatischen Schäden aus. Wir geben Beispiele für die Reparatur von DNA‐Nanostrukturen, die den Unterschied zwischen unspezifischer Selbstregeneration und schadensspezifischer Selbstheilung aufzeigen. Anhand von DNA‐Origami‐Nanolinealen, die mit Rasterkraftmikroskopie und DNA‐PAINT‐Superauflösungs‐Mikroskopie untersucht wurden, demonstrieren wir die quantitative Aufrechterhaltung der Fluoreszenzeigenschaften mit direktem Potenzial zur Verbesserung nanoskaliger Kalibrierproben. [ABSTRACT FROM AUTHOR]

Die Einführung von mRNA in Zellen hat in vielen Anwendungsbereichen starkes Interesse geweckt, doch für eine erfolgreiche Einführung sind spezifische Lösungen erforderlich. Technisch hergestellte Nanomaterialien wurden bereits als mRNA‐Nanoträger eingesetzt; ihre Funktionen wurden hauptsächlich als Boten konzipiert, aber nur selten auch für die Regulation der Proteintranslation. Jüngste Fortschritte in der Konzipierung von mRNA‐Nanoträgern gehen von einfachen Bereitstellungswerkzeugen zu komplexen Translationsmodulatoren über. In diesem Kurzaufsatz diskutieren wir moderne Konzepte von Nanomaterialien, welche die mRNA‐Translation regulieren, sowie neuere Fortschritte der mRNA‐Bereitstellung. Ebenfalls betrachtet werden spezifisch entwickelte, funktionelle Nanomaterialien für vielseitige mRNA‐Anwendungen, um Erkenntnisse für die Konzipierung von Nanomaterialien der nächsten Generation zu gewinnen, die die mRNA‐Technologie revolutionieren sollen. [ABSTRACT FROM AUTHOR]

Out‐of‐school learning settings are widely spread throughout Germany. STEM student labs are one particular type of out‐of‐school learning settings, which constitute a beneficial addition to STEM school lessons as they are not part of the school curriculum. Through these student labs, students can engage in highly relevant and complex scientific content areas in an authentic environment. In this article, the student lab program nawi:klick!, taking place at the Forschungswerkstatt in Kiel, Germany, will be presented. This program focuses on the presentation of nanotechnological contents and nanosciences in daily life. Based on adjacent questionnaires it could be shown that the learning setting indeed offers perceived knowledge gains as well as a development of students' experimental competences and that the intended relevance for students' daily lives is recognized. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Economic Sciences, Management & Commercial Sciences (JESMCS) is the property of Association of Arab Universities and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Biotechnologie, Agronomie, Societe et Environnement is the property of Les Presses Agronomiques de Gembloux and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of HNO is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Noninvasive regulation of CRISPR/Cas9 gene editing is conducive to understanding of gene function and development of gene therapy; however, it remains challenging. Herein, a photolabile semiconducting polymer nanotransducer (pSPN) is synthesized to act as the gene vector to deliver CRISPR/Cas9 plasmids into cells and also as the photoregulator to remotely activate gene editing. pSPN comprises a 1O2‐generating backbone grafted with polyethylenimine brushes through 1O2‐cleavable linkers. NIR photoirradiation spontaneously triggers the cleavage of gene vectors from pSPN, resulting in the release of CRISPR/Cas9 plasmids and subsequently initiating gene editing. This system affords 15‐ and 1.8‐fold enhancement in repaired gene expression relative to the nonirradiated controls in living cells and mice, respectively. As this approach does not require any specific modifications on biomolecular components, pSPN represents the first generic nanotransducer for in vivo regulation of CRISPR/Cas9 gene editing. [ABSTRACT FROM AUTHOR]

We present the synthesis of metal nanowires in a multiplexed device configuration using single‐walled carbon nanotubes (SWNTs) as nanoscale vector templates. The SWNT templates control the dimensionality of the wires, allowing precise control of their size, shape, and orientation; moreover, a solution‐processable approach enables their linear deposition between specific electrode pairs in electronic devices. Electrical characterization demonstrated the successful fabrication of metal nanowire electronic devices, while multiscale characterization of the different fabrication steps revealed details of the structure and charge transfer between the material encapsulated and the carbon nanotube. Overall the strategy presented allows facile, low‐cost, and direct synthesis of multiplexed metal nanowire devices for nanoelectronic applications. [ABSTRACT FROM AUTHOR]

Single‐molecule devices attract much interest in the development of nanoscale electronics. Although a variety of functional single molecules for single‐molecule electronics have been developed, there still remains the need to implement sophisticated functionalization toward practical applications. Given its superior functionality encountered in macroscopic materials, a polymer could be a useful building block in the single‐molecule devices. Therefore, a molecular junction composed of polymer has now been created. Furthermore, an automated algorithm was developed to quantitatively analyze the tunneling current through the junction. Quantitative analysis revealed that the polymer junction exhibits a higher formation probability and longer lifetime than its monomer counterpart. These results suggest that the polymer provides a unique opportunity to design both stable and highly functional molecular devices for nanoelectronics. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Machine Construction & Maintenance is the property of Institute for Sustainable Technologies - National Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Anthropologia Integra is the property of Masaryk University, Department of Anthropology, Faculty of Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Reversible oxidation reactions in electrochemically switchable oligorotaxanes with tetrathiafulvalene (TTF) decorated 24‐crown‐8 ether wheels generate intramolecular mixed‐valence and radical‐cation interactions between the wheels. This induces shuttling of the wheels and a contraction of inter‐wheel distances. Further oxidation generates repulsive forces between the TTFs and maximizes the inter‐wheel distances instead. These interactions and co‐conformational changes were not observed for structurally similar controls in which acetyl groups along the axle prevent translational motion of the wheels. This operation mode of oligorotaxanes, which is reminiscent of an accordion‐like motion, is promising for functional materials and nanodevices such as piston‐type rotaxane motors. [ABSTRACT FROM AUTHOR]

Die Experimentierkoffer SimplyNano 1 und 2 wurden von der Innovationsgesellschaft mbH entwickelt und von der SimplyScience Stiftung herausgegeben. Sie enthalten Unterrichtsunterlagen für die Erklärung und Vorstellung einfacher Phänomene der Nanotechnologie. Es stehen Schüleranleitungen, Kommentare für Lehrpersonen und Vortragsfolien zur Verfügung. Weiterführende Unterlagen und Ideen zu Nanotechnologie im Unterricht bietet die Plattform Swiss Nano-Cube.

The evolution of DNA microarray technology has led to sophisticated DNA chips that are being used as routine tools for fundamental and applied genome research such as genotyping and expression profiling. Owing to their capability for highly parallel, site‐directed immobilization of complementary nucleic acids through canonical Watson–Crick base‐pairing, however, DNA‐modified surfaces can also be used for the assembly of complex surface architectures comprised of non‐nucleic acid compounds, such as proteins or colloidal materials. Furthermore, implementation of functional DNA devices and structural DNA nanotechnology can unlock the full potential of DNA surfaces. Based on case studies from diagnostics, sensing, proteome research, cell adhesion, and cell signaling, we show how classical gene sensors have developed into modern integrated systems and platforms for various applications in life sciences and materials research. [ABSTRACT FROM AUTHOR]

In situ surface‐enhanced Raman spectra of the headspace above cultures of six bacterial species showed strong characteristic bands from chemisorbed methyl sulfide. This marker compound is created by dissociation of dimethyl disulfide (DMDS), a fermentative metabolite of bacteria, on the surface of the enhancing Au or Ag nanoparticle films. Kinetic binding plots of media spiked with DMDS and of live cultures showed that the Au‐based substrates were more suitable for the rapid detection of bacteria than Ag‐based substrates. For E. coli DH5α, the sensitivity limit for headspace SERS detection was 1.5×107 CFU mL−1, which corresponded to detection 15 min after inoculation of the growth medium. Since the metabolites are only produced by viable bacteria, antibiotic (gentamicin) treatment stopped the normal signal growth of the marker peak. This work is a promising step towards rapid bedside detection of bacterial infections and rapid screening of antibiotics against bacteria. [ABSTRACT FROM AUTHOR]

Summary Experiments with gold nanoparticles can often not be carried out at school, since the required precursors containing gold are too expensive. The following article presents a practicable solution for the processing of gold‐bearing electronic waste, which is often disposed of carelessly with residual waste even in schools. The gold acid obtained herein is used for the synthesis of the gold nanoparticles mentioned. In addition to the series of experiments, critical approaches concerning improper recycling in parts of the Third World and the high material values, which are wasted unnoticed in our society, are discussed in class. [ABSTRACT FROM AUTHOR]

Abstract: Precise control of the molecular arrangements at the interface between the electron donor and acceptor in mixed bulk heterojunctions (BHJs) remains challenging, despite the correlation between structural characteristics and efficiency in organic photovoltaics (OPVs). This study reveals that the substitution patterns of linear and branched alkyl side chains on electron‐donating/‐accepting alternating copolymers can control the positions of an acceptor molecule (C60) around the π‐conjugated main chains in mixed BHJs. Two‐dimensional solid‐state NMR demonstrates a marked difference in the location of C60 in the blend films. A copolymer with an electron‐accepting unit positioned in close proximity to C60 demonstrated higher OPV performance in combination with various fullerene derivatives. This molecular design offers precise control over the interfacial molecular structure, thereby paving the way for overcoming the current limitations of OPVs comprising mixed BHJs. [ABSTRACT FROM AUTHOR]

Abstract: We show how the redox potentials of carbon nanodots (CNDs) can be modulated by employing quinones as electroactive precursors during a microwave‐assisted synthesis. We prepared and characterized a redox library of CNDs, demonstrating that this approach can promote the use of carbon nanodots for ad hoc applications, including photocatalysis. [ABSTRACT FROM AUTHOR]

Abstract: Viele moderne Technologien und insbesondere die molekulare Sensorik beruhen auf Innovationen im Design neuer Moleküle. Das Design neuartiger, molekularer Sensoren ist erforderlich, um chemische und biologische Signale zu erfassen und somit kostengünstige, allgegenwärtige Chemosensoren zu entwickeln. Wir sind für viele neue Innovationen bereit, um neue Generationen von Sensortechnologien zu realisieren. Heutige Hardware zu erweitern, deren Kosten zu senken und eine breite Implementierung molekularer Sensorik sicherzustellen, ist nur mithilfe dieser neuartigen Materialien und Moleküle möglich. [ABSTRACT FROM AUTHOR]

Copyright of SWS - Rundschau is the property of Verein fur interdisziplinare sozialwissenschaftliche Studien und Analysen and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract: Multicompartment micelles (MCPs), comprising sequences of repeated elemental discoid parts connected by fasciculus, were formed by self‐assembly of polystyrene‐block‐poly(2‐vinyl pyridine)‐block‐poly(ethylene oxide). Using an electrostatic field, the MCPs can be disassembled through consequent release of small spherical micelles. During this disassembly process, release of loaded species can be achieved from the micelles in chronological order. Two location‐selected cargos (mitoxantrone (MTNT) and fluorescein isothiocyanate (FITC)) in the outer and inner compartments of the micelles can be released in chronological order. Under the applied electrostatic field (intensity: 16 kV cm−1), the loaded MTNT was rapidly released with more than 80 % release, whereas the loaded FITC was slowly released with less than 20 % release in 12 h. At a later stage (after more than 12 h), the loaded MTNT was slowly released with less than 20 % release, while the loaded FITC was rapidly released with more than 80 % release. [ABSTRACT FROM AUTHOR]

Der menschliche Körper ist auffällig mit der Aufforderung zur Veränderung und Überschreitung eines vorgefundenen Zustands verbunden. Die Plastizität des Körpers erlaubt dabei ein gehöriges Quantum Transition. Der Transhumanismus, eine neuere philosophisch-naturwissenschaftliche Bewegung, antwortet entsprechend auf die Grundfrage der Anthropologie mit dem Hinweis auf diese Überschreitungspotentiale und auf die Grundfrage der Ethik mit einem Imperativ zur akzelerierten technischen Verbesserung menschlicher Körper. Auf die Frage nach der Methode antwortet der Transhumanismus unter anderem mit Verweis auf Nanotechnologien und die Vorstellung nanokleiner Werkzeuge, mit deren Hilfe die Materie auf Zellebene kontrolliert werden soll. Zwar ist das Thema Transhumanismus in der theologischen Debatte bisher wenig vorgekommen, allerdings werden einzelne Aspekte transhumaner Visionen diskutiert. Einige aktuelle theologische Stellungnahmen, überwiegend katholischer Provenienz, immunisieren sich gegen ein konstruktives Gespräch mit dem Transhumanismus, in dem Ketzerhüter verteilt und invasive Körpermodifikationen als Neuauflage klassischer Häresien aufgefasst werden. In komparativer Perspektive ist aber ein Zugang innerhalb der Theologie denkbar, der zwar nicht jede invasive Körpermodifikation vorschnell begrüßen, aber auch nicht exorzieren muss. Die Hoffnung auf Fortschritt animiert einen Konnex zwischen Theologie und Transhumanismus, wobei auch erhebliche technische Modifikationen dazu beitragen könnten, menschliche Körper-Wünsche nicht allein auf eine gedachte Zukunft bei Gott zu beziehen. [ABSTRACT FROM AUTHOR]

Abstract: Scalable methods currently are lacking for isolation of long ssDNA, an important material for numerous biotechnological applications. Conventional biomolecule purification strategies achieve target capture using solid supports, which are limited in scale and susceptible to contamination owing to nonspecific adsorption and desorption on the substrate surface. We herein disclose selective nascent polymer catch and release (SNAPCAR), a method that utilizes the reactivity of growing poly(acrylamide‐co‐acrylate) chains to capture acrylamide‐labeled molecules in free solution. The copolymer acts as a stimuli‐responsive anchor that can be precipitated on demand to pull down the target from solution. SNAPCAR enabled scalable isolation of multi‐kilobase ssDNA with high purity and 50–70 % yield. The ssDNA products were used to fold various DNA origami. SNAPCAR‐produced ssDNA will expand the scope of applications in nanotechnology, gene editing, and DNA library construction. [ABSTRACT FROM AUTHOR]