Search

BACKGROUND: Maximum oxygen consumption (VO2max), an essential indicator of integrated function of the cardiovascular, respiratory, and muscular systems, is an excellent predictor of all-cause morbidity and mortality. Direct measurement is a sophisticated procedure which for some individuals is difficult to perform. The use of international formulae leads to overestimation or underestimation of values. Therefore, the present study aimed to generate a best-fit VO2max prediction formula for young Saudi females. MATERIALS AND METHODS: One hundred and two randomly selected young healthy Saudi females (19–25 years) with normal body mass index (18.5–24.99 kg m−2) and sedentary lifestyle underwent maximum cardiopulmonary exercise testing on cycle ergometer when using breath-by-breath analyzing system. Hemodynamic and ventilatory parameters were assessed before and during the maximum exercise. Significantly correlated exercise and nonexercise parameters enterd in multiple linear regression analysis to find the best-fit model, and used to generate a VO2max prediction formula. RESULTS: The mean measured VO2max was 1449.1 ± 233.92 ml min−1. The VO2max prediction formula was 1304.193 ± 17.902 × body weight + 43.857 × time until exhaustion − 6.83 × maximum heart rate. The mean calculated VO2max was 1449.14 ± 143.97 ml min−1. No statistically significant difference was observed between the measured and calculated VO2max. The Bland–Altman test for the limit of agreement was performed and showed good agreement between the two values with a minute proportional bias. The standard error of the estimate was 156.34, which is approximately 10.6% of the mean measured VO2max. Reliability analysis yielded a Cronbach’s alpha of 0.709. CONCLUSION: This study presents a reliable and valid VO2max prediction formula for young Saudi females. This nationally generated formula is far more representative of the VO2max value than international formulae. We recommend the implementation of this formula and an investigation of its validity in other Saudi population groups.

Maximum oxygen consumption is an informative indicator of aerobic performance, and its assessment is associated with a significant investment of time. The paper compares the results of maximum tests with a stepwise increasing load with different duration of one load step: 15, 30, 60, 120, and 240 s. Maximum oxygen uptake, total operating time, and pair-wise relationship of protocols were assessed. There was no statistically significant difference in maximum oxygen uptake rate in protocols of different duration. Also, all the studied protocols showed a high correlation with each other (r = 0.92–0.97). [ABSTRACT FROM AUTHOR]

Background and Objectives: Most research studies on the effects of repeated plasma donation are observational with different study limitations, resulting in high uncertainty on the link between repeated plasma donation and health consequences. Here, we prospectively investigated the safety of intensive or less intensive plasma donation protocols. Materials and Methods: Sixty‐three male subjects participated in this randomized controlled trial and were divided into low‐frequency (LF, once/month, n = 16), high‐frequency (HF, three times/month, n = 16), very high‐frequency (VHF, two times/week, n = 16) and a placebo (P, once/month, n = 15) groups. Biochemical, haematological, clinical, physiological and exercise‐related data were collected before (D0), after 1½ months (D42) and after 3 months (D84) of donation. Results: In VHF, red blood cells, haemoglobin and haematocrit levels decreased while reticulocyte levels increased from D0 to D84. In both HF and VHF, plasma ferritin levels were lower at D42 and D84 compared to D0. In VHF, plasma levels of albumin, immunoglobulin G (IgG), immunoglobulin A (IgA) and immunoglobulin M (IgM) dropped from D0 to D42 and remained lower at D84 than at D0. In HF, plasma IgG, IgA and IgM were lower at D42, and IgG and IgM were lower at D84, compared to D0. Few adverse events were reported in HF and VHF. Repeated plasma donation had no effect on blood pressure, body composition or exercise performance. Conclusion: VHF plasmapheresis may result in a large reduction in ferritin and IgG levels. HF and VHF plasmapheresis may result in little to no difference in other biochemical, haematological, clinical, physiological and exercise‐related parameters. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Prescrição e Fisiologia do Exercício is the property of Instituto Brasileiro de Pesquisa e Ensino em Fisiologia do Exercicio and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Evaluation of cardio-respiratory endurance in individuals with different levels of blood pressure is one of the key factors in preventing the development of diseases of the cardiovascular system. The purpose of the study was to conduct a comparative assessment of cardio-respiratory endurance, the level of maximum oxygen consumption, and the results of the Ruffier test in individuals with different blood pressure levels. 320 people were examined, of which 4 groups were formed according to the initial level of blood pressure. After measuring baseline blood pressure and heart rate, all subjects underwent a Ruffier test (30 sit-ups for 45 seconds), followed by repeated heart rate measurements at 15 seconds, 1 minute, and blood pressure measurements at 3 minutes. Determination of the level of maximum oxygen consumption was performed according to the formula. Representatives of the group with normal-low and normal blood pressure have a significantly higher level of maximum oxygen consumption. Individuals with normal-high blood pressure and first-degree hypertension had higher levels of systolic and diastolic blood pressure during daily blood pressure monitoring, both during the day and at night, compared to individuals with normal and normal-low blood pressure. It was established that people with normal-low blood pressure have a higher cardio-respiratory endurance than people with normal-high blood pressure and first-degree hypertension. The findings of the study can be used by cardiologists and general practitioners for early detection and prevention of diseases of the cardiovascular system, and physiologists in further investigation of the features of the functioning of the cardiovascular system

Ill-planned irrigation systems and pesticide overuse during 1950-1960 severely impacted the soil system in the Aral Sea region. Organochlorine compounds including DDT (dichlorodiphenyltrichloromethylmethane), DEE (dichlorodiphenyldichloroethylene), DDD (dichlorodiphenyldichloromethane), HCCH (hexachlorane) and toxic metals are readily available in soil systems. Thus, long-term exposure to these toxic environmental conditions increases the health risk of the people. Hence, this study investigates environmental influence on the development of power motor qualities, physical endurance, and oxygen capacity in young people living in this region. The study cohort included 609 volunteers aged 18-25 in two different geographical regions, North and Nukus in Uzbekistan. All participants were assessed based on the one-mile walking test for strength motor qualities, dynamic and static power endurance, and maximum oxygen consumption (MOC) in addition to hematological indices. Data analysis revealed significantly lower values of all fitness test parameters and MOC in young men and only parameters of dynamic power endurance living in the North region. Both male and female participants of the North cohort had lower red blood cell (RBC) and hemoglobin (Hb) levels compared to the cohort from Nukus. A high prevalence (28% of males and 96% of females) and the nature of anemia (normocytic and normochromic) were found. This study has sufficiently characterized the change in muscular strength and physical endurance in youth in this region. The decrease of MOC and muscle strength and endurance in young men and women may have an influence from organochlorine pesticides on haemopoiesis and subsequent decreasing of oxygen capacity in the blood.

Purpose: To appraise the effects of incremental aerobic training (IAT) on systemic inflammatory mediators, cardiorespiratory indices, and functional capacity in obese children with bronchial asthma. Methods: This study included 30 children with asthma (age = 8–16 y) allocated randomly into either the control group (n = 15; received the traditional pulmonary rehabilitation program) or IAT group (n = 15; engaged in 8 weeks of IAT in addition to the traditional pulmonary rehabilitation program). The systemic inflammatory mediators (high-sensitivity C-reactive protein and interleukin-6), cardiorespiratory indices (peak oxygen uptake, minute ventilation, maximum heart rate, heart rate recovery at 1 min after exercises, and oxygen pulse), and functional capacity (represented by 6-min walk test) were analyzed pretreatment and posttreatment. Results: A significant reduction in the level of high-sensitivity C-reactive protein and interleukin-6 and increase in peak oxygen uptake, minute ventilation, maximum heart rate, and heart rate recovery at 1 minute after exercises was observed among the IAT group as compared with the control group. In addition, the IAT group covered a longer distance in the 6-minute walk test than the control group, suggesting favorable functional capacity. Conclusion: The study results imply that IAT has the potential to improve the inflammatory profile, cardiorespiratory fitness, and functional capacity of obese children with bronchial asthma. [ABSTRACT FROM AUTHOR]

Background: The aim of this review study was to compare the effect of high-intensity interval training (HIIT), and moderate-intensity continuous training (MICT) on cardiometabolic factors in children and teenagers with overweight and obesity. Materials and Methods: A systematic search was conducted in PubMed, Web of Science, SID, Magiran, and Google Scholar databases for English and Persian articles published until December 2022. A meta-analysis was performed to compare the effect of HIIT and MICT on cardiometabolic factors (body fat percentage, free fat mass, maximum oxygen consumption, systolic blood pressure (SBP), and diastolic blood pressure (DBS) in children and teenagers with overweight and obesity. Results: The results of 15 studies with 429 children and teenagers with overweight and obesity showed that HIIT caused a significant decrease in body fat percentage [WMD=-0.59, P=0.04], and SBP [WMD=-1.98, P=0.004]. In addition, the results showed that HIIT caused a significant increase in the maximum oxygen consumption [SMD=0.65, P=0.001], compared to MICT in children and teenagers with overweight and obesity. In contrast, HIIT causes a non-significant change in free fat mass [WMD=0.65, P=0.5], serum HDL [SMD=0.06, (CI: P=0.5], DBP [WMD=-0.6, P=0.7], and body weight [WMD=-0.33, P=0.7], compared to MICT in children and teenagers with overweight and obesity. Conclusion: HIIT reduces body fat percentage and SBP, and increases maximum oxygen consumption, compared to MICT in children and teenagers with overweight and obesity. Therefore, HIIT is recommended as a non-drug solution to reduce cardiometabolic risk factors in children and teenagers with overweight and obesity.

This study aims to determine the effect of motivation, self-confidence, and maximum oxygen consumption on the basic skills of playing soccer. This research includes path analysis research (path analysis). Exogenous variables are motivation (x1), confidence (x2), and maximum oxygen consumption (x3), while endogenous variables are the basic skills of playing soccer. The sample of this research was 100 male students of class XI MAN 2 Bone. Data were analyzed by inferential statistical analysis, namely the regression test. The findings showed that motivation (MTV), self-confidence (PD), and maximum oxygen ability (VO2 max) affected the basic skills of playing soccer (KSB) (p

The study aims to know the effect of cross-training on each of the maximum oxygen consumption, the level of motor performance for aerobic gymnastics. As for the study approach, the researcher used the experimental approach by choosing one of its designs (pre-measurement - post-measurement) for one experimental group, due to their suitability to the nature and purpose of the study. The study is for female students of the fourth year, a training division specializing in artistic gymnastics for the academic year 2020/2021, who are enrolled in the College of Physical Education for Girls in Al-Jazirah, The researcher chose the sample of the study by the intentional method, as they numbered (59) students, whose ages ranged between (21-23) years, and (30) students who did not practice sports activities were selected (50%) of the study population, and they were divided into (4) students. To conduct the exploratory study and the number of (26) female students for the experimental group, The researcher used data collection tools (stopwatch to calculate time - a medical scale for measuring weight in kilograms - a rectameter device for measuring height - a medicine ball - a jump rope - agility ladder - jumping box - parallel bar (girls) - cones). The maximum oxygen consumption), and the training program (Cross Fit) had a positive effect on the level of motor performance of the aerobic gymnastics of the female players. [ABSTRACT FROM AUTHOR]

Introduction: It has been proven that the chronotype plays a key role in the timing of peak sports performance. Recent evidence suggests that investigating these differences, which are known as chronotypes, leads to different daily physiological profiles. This research aimed to investigate the effect of chronotype on the maximum oxygen consumption (Vo2max), melatonin, and body temperature of the youth football players of Sanat Mes Kerman Club. Methods: In this quasi-experimental research, 30 young male football players of Sanat Mes Kerman Club with a mean age of 16.26 years old were selected as statistical samples. Based on the Morningness-Eveningness Questionnaire (MEQ), participants were classified into morning and evening types. To perform the incremental treadmill test, participants attended three sessions in the laboratory (7:00 to 9:00 in the morning and 6:00 to 8:00 in the evening). The participants’ blood melatonin levels and body temperature were measured before performing the test and the oxygen consumption was measured during the test. Results: In the morning type group, there was no significant difference between Vo2max and melatonin in the morning and evening conditions (p>0.05), but in the evening type group the body temperature showed a significant increase compared to the morning type group (p<0.005). In the evening type group, there was no significant difference between melatonin levels in morning and evening conditions (p>0.05), but in the evening type group, the body temperature (p<0.023) and Vo2max (p<0.001) showed a significant increase compared with the morning type group. Conclusion: It seems that the chronotype affects the aerobic capacity of athletes. In people with evening type chronotype, aerobic capacity is sometimes higher during the evening physical activity hours compared with the morning physical activity. [ABSTRACT FROM AUTHOR]

Copyright of Health Sport Rehabilitation is the property of H.S. Skovoroda Kharkiv National Pedagogical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The practice of racket sports has had an exponential growth in the last decade, along with it, the scientific interest in researching the different disciplines: badminton, padel, table tennis, tennis, and squash. However, most research has focused on the technical and tactical field. Therefore, the aim of this review is to analyze and compare the indicators of the internal load of each sport: heart rate (HR), maximum oxygen consumption (VO2max), oxygen consumption (VO2), and lactate (LA) in order to reset physiological references to adjust the training of the players and also use these references to propose the practice of these sports for healthy purposes to the general population. PRISMA Guidelines for Systematic Review were used to search for articles that met the inclusion criteria in three databases: Web of Science, Pubmed, and Sportdiscus. The search was performed between January 2010, and September 2022. Finally, a total 27 records were included for analysis in this study. The main findings were related to the differences in the intensity rates between sports. The highest lactate concentrations and heart values were found in badminton in the intensity of effort values (whose highest values were found in badminton) 10.11 (±4.99) mmol/L and 182.6 (±2.7) bpm respectively, whereas table tennis showed the lowest ones 1.2 (± 0.4) mmol/L, and 103.99 (±15.09) bpm, respectively. The highest mean VO2 was found in table tennis with a value of 36.8 (±13.2) ml/kg/min and the lowest in tennis with a value of 26.6 (±2.7) ml/kg/min. The highest VO2max was found in tennis players 58.0 (±4.6) ml/kg/min, and the lowest value was in table tennis with a value of 42.9 (±4.2) ml/kg/min. Since most of the studies were carried out on elite men players, future research should focus on amateur and women level players. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Prescrição e Fisiologia do Exercício is the property of Instituto Brasileiro de Pesquisa e Ensino em Fisiologia do Exercicio and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The practice of racket sports has had an exponential growth in the last decade, along with it, the scientific interest in researching the different disciplines: badminton, padel, table tennis, tennis, and squash. However, most research has focused on the technical and tactical field. Therefore, the aim of this review is to analyze and compare the indicators of the internal load of each sport: heart rate (HR), maximum oxygen consumption (VO2max), oxygen consumption (VO2), and lactate (LA) in order to reset physiological references to adjust the training of the players and also use these references to propose the practice of these sports for healthy purposes to the general population. PRISMA Guidelines for Systematic Review were used to search for articles that met the inclusion criteria in three databases: Web of Science, Pubmed, and Sportdiscus. The search was performed between January 2010, and September 2022. Finally, a total 27 records were included for analysis in this study. The main findings were related to the differences in the intensity rates between sports. The highest lactate concentrations and heart values were found in badminton in the intensity of effort values (whose highest values were found in badminton) 10.11 (±4.99) mmol/L and 182.6 (±2.7) bpm respectively, whereas table tennis showed the lowest ones 1.2 (± 0.4) mmol/L, and 103.99 (±15.09) bpm, respectively. The highest mean VO2 was found in table tennis with a value of 36.8 (±13.2) ml/kg/min and the lowest in tennis with a value of 26.6 (±2.7) ml/kg/min. The highest VO2max was found in tennis players 58.0 (±4.6) ml/kg/min, and the lowest value was in table tennis with a value of 42.9 (±4.2) ml/kg/min. Since most of the studies were carried out on elite men players, future research should focus on amateur and women level players.

This research aims to identify the effect of trampoline exercises on the maximum oxygen consumption and muscle strength of obese from 20 – 30 years. The research was applied to a sample of 25 women, including 10 women for the exploratory experiment and 15 women for the basic sample, The most important results showed that the training program using the trampoline had a positive effect in improving the ratios of both the maximum oxygen consumption and muscle strength on the experimental research sample. [ABSTRACT FROM AUTHOR]

All known species of the Triassic archosauromorph genus Tanystropheus are known to have had the longest neck in proportion to their torso. This feature is related to a series of ventilatory challenges since an increase in neck length also increases airway length and, therefore, the volume of stagnant air that does not reach the lungs, the dead space volume. Based on this challenge, the objective of the present study was to model the type of respiratory system of Tanystropheus able to meet its metabolic demands during the early Triassic period. The modeling was based on allometric relations for morphological and physiological ventilatory and metabolic variables, and to do so, the mean body mass of Tanystropheus was estimated based on three different methods. In addition, the tracheal airflow was also estimated based on the proportions of Tanystropheus elongated neck, the results of allometric modeling, and fundamental equations of fluid mechanics. The estimation of the body mass indicated that an animal of 3.6 m would possess a body mass of 50.6 ± 21.6 kg. Allometric modeling suggested that the respiratory system best suited to Tanystropheus' oxygen demands, especially during activity, would be a generic reptilian-like respiratory system composed of multicameral lungs. The best respiratory pattern to maintain adequate tracheal flow rates and effective pulmonary ventilation would be one ventilating the relatively narrower trachea at lower frequencies to deal with tracheal dead space volume. [ABSTRACT FROM AUTHOR]

IntroductionExposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to-forced vital capacity ratio, FEV1/FVC). The significance of lung volumes that reflect air trapping in the presence of preserved spirometry is unclear.MethodsTo investigate whether lung volumes representing air trapping could determine susceptibility to respiratory morbidity in people with SHS exposure but without spirometric chronic obstructive pulmonary disease, we examined a cohort of 256 subjects with prolonged occupational SHS exposure and preserved spirometry. We elicited symptom prevalence by structured questionnaires, examined functional capacity (maximum oxygen uptake, VO2max) by exercise testing, and estimated associations of those outcomes with air trapping (plethysmography-measured residual volume-to-total lung capacity ratio, RV/TLC), and progressive air trapping with exertion (increase in fraction of tidal breathing that is flow limited on expiration during exercise (per cent of expiratory flow limitation, %EFL)).ResultsRV/TLC was within the predicted normal limits, but was highly variable spanning 22%±13% and 16%±8% across the increments of FEV1/FVC and FEV1, respectively. Respiratory complaints were prevalent (50.4%) with the most common symptom being ≥2 episodes of cough per year (44.5%). Higher RV/TLC was associated with higher OR of reporting respiratory symptoms (n=256; r2=0.03; p=0.011) and lower VO2max (n=179; r2=0.47; p=0.013), and %EFL was negatively associated with VO2max (n=32; r2=0.40; p=0.017).ConclusionsIn those at risk for obstruction due to SHS exposure but with preserved spirometry, higher RV/TLC identifies a subgroup with increased respiratory symptoms and lower exercise capacity.

This study investigated the associations between relative telomere length (RTL) and resting metabolic rate (RMR), resting fat oxidation (RFO), and aerobic capacity and whether oxidative stress and inflammation are the underlying mechanisms in sedentary women. We also aimed to determine whether the correlations depend on age and obesity. Sixty-eight normal weight and 66 obese women participated in this study. After adjustment for age, energy expenditure, energy intake, and education level, the RTL of all participants was negatively correlated with absolute RMR (RMRAB) and serum high-sensitivity C-reactive protein (hsCRP) concentration, and positively correlated with maximum oxygen consumption ( V ˙ O2max) (all p < 0.05). After additional adjustment for adiposity indices and fat-free mass (FFM), RTL was positively correlated with plasma vitamin C concentration (p < 0.05). Furthermore, after adjustment for fasting blood glucose concentration, RTL was negatively correlated with age and positively correlated with V ˙ O2max (mL/kg FFM/min). We found that normal weight women had longer RTL than obese women (p < 0.001). We suggest that RTL is negatively correlated with RMRAB and positively correlated with aerobic capacity, possibly via antioxidant and anti-inflammatory mechanisms. Furthermore, age and obesity influenced the associations. We provide useful information for the management of promotion strategies for health-related physical fitness in women. [ABSTRACT FROM AUTHOR]

We investigated the effects of Irvingia gabonensis (IG) kernel extract on the metabolism, adiposity indices, redox status, inflammation, adipocytokines, blood leukocyte relative telomere length (RTL), and aerobic capacity of overweight/obese individuals. All participants used the first 12-week phase to monitor body weight. They were then randomly divided into two groups: (1) 300 mg IG or (2) placebo (PLA). Both groups took one tablet per day for 12 weeks. The variables were measured before supplementation and after 3, 6, and 12 weeks of supplementation. RTL and aerobic capacity were measured before and after 12 weeks. Compared with the PLA, the IG increased plasma vitamin C after supplementation at 6 (p < 0.01) and 12 weeks (p < 0.05) and serum adiponectin after 3 weeks (p < 0.05). Compared with before supplementation, plasma malondialdehyde in the IG and serum leptin in the PLA were decreased after 12-week supplementation, without any differences between the groups. There were no differences between groups with respect to metabolism, inflammation, RTL, and aerobic capacity after the supplementation. We suggest that 12-week daily IG supplementation improved plasma vitamin C and adiponectin. The findings show the possible mechanism contributing to the effect of IG supplementation on a reduction in obesity-related complications. [ABSTRACT FROM AUTHOR]

Introduction: The variables of body composition and aerobic performance are decisive to evaluate the profiles of soccer players, for this reason the sports scientific community is in constant search of information on what values to discriminate to generate training strategies more in line with this type of population. The aim of this research is to compare the maximum oxygen consumption and body composition according to game position and study their relationship. Material and methods: This study has a descriptive, comparative and correlational design. The study was conducted with 26 professional female players (25.5 ± 4.0 years; body mass of 57.7 ± 5.0 kg; the height of 161.7 ± 5.7 cm) from a Chilean first division soccer club. For the evaluation of body composition, body mass (BM), standing height, perimeters, sum of six skinfolds (Σ6 skinfolds), estimated percentage of muscle mass (%MM) and percentage of body fat (%BF). For aerobic performance, VO2max was evaluated by means of this test, the following variables were determined: maximum relative oxygen consumption (VO2max ml/kg/min), maximum aerobic speed (MAS km/h), ventilatory threshold velocity 1 and 2 (VT1 and VT2 km/h), percentage of ventilatory threshold VO2 1 and 2 (% VO2 VT1 and 2), ventilatory threshold heart rate 1 and 2 (HR VT1 and 2) and maximum heart rate (HRmax). Results: The goalkeepers as the central defenders presented a significantly lower %VO2 VT2 than the lateral defenders p = 0.043 and p = 0.012 respectively. Comparisons of body composition variables according to game position, no variable showed significant differences between game positions (p > 0.05). The simple linear regression (r2) that showed the greatest explanation between variables was VO2max (ml/kg/m) with BM (r2 = 0.220), MAS km/h (r2 = 0.480), VT1 speed (r2 = 0.412) and VT2 speed (r2 = 0.613). Conclusion: The variables MAS and Vel VT1 and VT2 seem to be elements that have a high explanation of the variance in VO2max, therefore, it is suggested to consider these elements as a guide in the planning of aerobic or continuous interval training, in order to better VO2max performance. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to determine the acute and chronic effects of interval aerobic exercise on hepcidin, ferritin, and liver enzymes in adolescents with beta-thalassemia major., Methods: Twenty-six beta-thalassemia major adolescents referred to the Thalassemia Clinic and Research Center were selected as study participants and randomly divided into control (n = 13) and training (n = 13) groups. Participants performed 3 sessions per week for 45 minutes in each session for 8 weeks of aerobic interval exercise with an intensity of 50% to 65% of the heart rate reserve. Blood samples were taken before, immediately after the exercise session, and 48 hours after the last training session, and liver enzymes aspartate aminotransferase, alanine aminotransferase (ALT), alkaline phosphatase (ALP), ferritin, and hepcidin were evaluated., Results: The results showed a decrease in aspartate aminotransferase, ALT, ALP, ferritin, and hepcidin levels due to 8 weeks of aerobic interval training (P = .14, P = .97, P = .03, P < .001, P < .001; respectively). Intergroup changes in all variables except ALT and hepcidin were significant (P < .05). Besides, acute aerobic exercise increased levels of aspartate aminotransferase, ALT, ferritin, and hepcidin (P = .04, P = .52, P < .001, P < .001; respectively), whereas ALP levels decreased (P < .001). In addition, changes in ALP and hepcidin levels were significant between the 2 groups (P = .05, P < .001; respectively)., Conclusion: Based on the study's results, it can be concluded that 8 weeks of aerobic interval training can decrease ferritin and hepcidin levels, but acute aerobic exercise increases them.

Purpose: Recovery after intense interval training plays an important role in improving athletic performance, while the type of recovery and exercise background can affect athletic performance. The aim of this study was to compare the Response of blood buffering capacity to three types of recovery during Repeated High-Intensity endurance test in trained and untrained girls' students of Farhangian University.Methods: 30 female students of Farhangian University (mean age 22.49 ±.3 (year), weight 68.33 ± 7.31 (kg) and height 176.76 ± 8.32 (cm) were randomly selected in three recovery groups (active: N=10, passive: N=10, Stretching: N=10) randomly. The Subjects underwent three types of recovery during the repeated high-intensity endurance test after evaluating the maximum oxygen consumption according to a specific pattern in a crossover methods, three days in a week. Arterial blood sample were taken measured before and immediately after the test and buffering capacity and carnosine were analyzed by ABG and ELISA techniques. After 8-eight weeks of aerobic exercise (65-80% of maximal heart rate), the test and blood sampling were repeated with the same pre-test and at the same time.Results: In untrained girls, only significant difference was found between stretching and active recovery for oxygen saturation, and in trained girls' there was a significant increase in oxygen saturation for active and passive recovery. Significant increase in blood acidity, bicarbonate, base buffers and carnosine was observed in trained girls by active recovery (P ≤ 0.05).Conclusion: The results show that the response of buffering capacity to the three types of recovery was significantly higher in trained subjects. Which is more notable with active recovery.

Oxygen delivery to cellular microdistricts is ensured by the coordinated work of systemic hemodynamics, microcirculation, and effective blood flow. However, the contribution of each link of this functional system with different oxygen supply to the body is insufficiently studied. The aim of the study was to conduct a comparative analysis of a set of indicators related to different levels of integration of the circulatory system in individuals with different levels of maximum oxygen consumption. Using the methods of viscometry, aggregatometry, and evaluation of the deformability of erythrocytes, the features of the hemorheological profile of individuals with different aerobic potential were determined. The registration of microcirculation parameters using biomicroscopy and laser Doppler imaging at rest and under conditions of intensive muscle work allowed us to obtain data on the state of microvessels and skin perfusion, as well as on the reserves of cutaneous blood flow in individuals with different levels of maximum oxygen consumption. The results indicate that high aerobic potential is combined with economical functioning of the circulatory system at rest not only at the level of macro-, but also microcirculation. Individuals with higher maximum oxygen consumption are characterized by increased reserves of microvascular perfusion, which are achieved due to a larger capillary diameter and moderately reduced blood viscosity. [ABSTRACT FROM AUTHOR]

Introduction: Maximal oxygen uptake (VO2 max) is the maximum quantity of oxygen a person can consume, and it remains constant over time despite increased exertion. The amount of oxygen consumed by the working muscles is measured by maximal oxygen consumption. The maximal oxygen uptake can be measured using maximal or submaximal tests, by gas analyser or field methods. The estimated VO2 max can be used to study people's fitness and raise awareness about physical activity and lifestyle changes. Aim: To determine the VO2 max values using a direct method and provide normative data of VO2 max for healthy young adults in the age group of 18-25 years in both sexes. Materials and Methods: This cross-sectional study was approved by the Institutional Ethical Committee of RUHS College of Medical Sciences, Jaipur, Rajasthan, India. A total of 419 healthy young adults (male and female students) were recruited from RUHSCollege of Medical Sciences and MNIT College, Jaipur, Rajasthan, India from January 2019 to March 2020. Anthropometric data included age, height, weight according to the National Health and Nutrition Examination Survey (NHANES) and followed by measurement of VO2 max using a gas analyser of AD-Instrument (model-ML206). Collected data was entered in Microsoft excel. Paired t-test was used to compare mean and Standard Deviation (SD) of variables between male and female participants. The p-value of <0.05 was considered as significant. Results: The study was conducted on 419 apparently healthy college students (275 male and 144 female). The mean VO2 max value for males was 45.30±7.35 mL/kg/min and for females it was 35.71±5.29 mL/kg/min, which was found to be significantly higher in males than in females. The mean VO2 max among the largest proportion of the males (27.63%) falls in the 'Good' category of cardiorespiratory fitness scale and the largest proportion of the females (32.63%) falls in the 'Fair' category of cardiorespiratory fitness scale. Conclusion: The value of VO2 max was lower in the Indian population than in the western population, when value obtained from this study was compared with the standard normative value of cardiorespiratory fitness. Therefore, the values obtained in this study could serve as a normative for the Indian population. [ABSTRACT FROM AUTHOR]

The performance and physical status of professional cyclists in Japan who train with pycnogenol-containing supplements have not been evaluated. This pilot study aimed to investigate how off-season training and ingesting PycnoRacer™ containing branched-chain amino acids (BCAAs) and pycnogenol can influence cycling performance in cyclists. Eight professional male cyclists (mean age, 24.0 ± 2.4 years) were included in this study. All athletes received and ingested PycnoRacer™ containing 60 mg of pycnogenol, 4,800 mg of BCAA, and 1,200 mg of arginine daily for 28 days. We evaluated the cycling performance and other parameters of each athlete before using PycnoRacer™ and after 28 days of training with the supplement. Measures of performance, such as maximum oxygen consumption, maximum aerobic power, and maximum heart rate, were evaluated with breath-by-breath exercise tolerance tests using a gas analyzer. Additionally, other parameters, including body composition, respiratory function, and degree of cycling training, were measured. The maximum oxygen consumption, maximum aerobic power, and caloric expenditure during cycling training increased significantly after 28 days of training with PycnoRacer™. However, no significant differences were found in the maximum heart rate, body composition, and respiratory function before and after using PycnoRacer™. Pycnogenol-containing supplements enhance off-season cycling performance and caloric expenditure during cycling training of professional cyclists.

Introduction: Maximal oxygen uptake (VO2 max) is the maximum quantity of oxygen a person can consume, and it remains constant over time despite increased exertion. The amount of oxygen consumed by the working muscles is measured by maximal oxygen consumption. The maximal oxygen uptake can be measured using maximal or submaximal tests, by gas analyser or field methods. The estimated VO2 max can be used to study people’s fitness and raise awareness about physical activity and lifestyle changes. Aim: To determine the VO2 max values using a direct method and provide normative data of VO2 max for healthy young adults in the age group of 18-25 years in both sexes. Materials and Methods: This cross-sectional study was approved by the Institutional Ethical Committee of RUHS College of Medical Sciences, Jaipur, Rajasthan, India. A total of 419 healthy young adults (male and female students) were recruited from RUHS-College of Medical Sciences and MNIT College, Jaipur, Rajasthan, India from January 2019 to March 2020. Anthropometric data included age, height, weight according to the National Health and Nutrition Examination Survey (NHANES) and followed by measurement of VO2 max using a gas analyser of AD-Instrument (model-ML206). Collected data was entered in Microsoft excel. Paired t-test was used to compare mean and Standard Deviation (SD) of variables between male and female participants. The p-value of

Featured Application: The study of men and women in middle and older middle age engaged in recreational cycling and running yielded data on the effects of these physical activities and showed an association between the physical activity, body composition, maximum oxygen consumption and maximum performance capacity during aging. Human physical activities may bring potential health benefits. The aim of our study was to compare body composition, lung function and aerobic fitness as a function of age in a cross-sectional study of 277 recreational cyclists (men: n = 163, women: n = 114) and 377 recreational runners (men: n = 239, women: n = 138) aged 20 to 60 years, with a training volume of about 2000 to 4000 km per year for cyclists and 25 to 60 km per week for runners. The survey focused on comparing the values of body composition, lung function and aerobic fitness in dependence on age. The results suggest that recreational cycling and running is associated with a favorable body composition and increased physical fitness, where the percentage of body fat in athletes corresponds to about 70–90% of the population norm, while physical fitness indices, maximum oxygen consumption and maximum exercise performance corresponded at about 140 to 150% of the population norms. The study confirms the assumption that the decrease in physiological functions and/or physical condition with age is much slower in those who participate in recreational sports than in the general nonsports population. [ABSTRACT FROM AUTHOR]

Running as an athletic discipline requires a high level of endurance and speed endurance, which is directly related to the cardiovascular and respiratory systems, ie the ability of an athlete's body to withstand loads, and the following are listed as relevant factors for running success: anaerobic strength and maximum O2 consumption, lactic acid concentration and oxygen deficiency, ability to withstand stress, high ability to concentrate and its retention over longer periods of time. There is a lot of research that has studied the parameters of functional abilities in an attempt to find the most effective way to improve them, and since there are many similar and different data on this topic, this paper has been done to classify the available papsers by domestic and foreign authors which would lead to conclusions applicable both in practice and for further research. For the purposes of this research, original scientific papers have been analyzed that dealt with functional abilities as success factors in short, middle and long distance running and the impact of training on functional abilities, found in electronic databases - Medline, PubMed, Researchgate, Web of Science and Google Scholar. The research used in this review monitored transversely the values ​​of submaximal and maximal oxygen consumption, energy systems, heart rate values, pulmonary ventilation, blood lactate concentration, as well as their changes after longitudinal implementation of experimental protocols and training processes. Since the collected research had too few respondents from different populations with a small number of elite runners, and they did not have enough information about many years of experience, level of sports form, race categories, and descriptions of training and methods, obtaining empirical information based on evidence was limited, as well as reaching valid conclusions. Accordingly, there is a need for a more systematic approach to research and implementation of complex studies with a sufficient number of runners of all ages, both sexes of the elite level, and cooperation of academic researchers, clubs and athletes to enable studies that would provide significant statistics, analysis and interpretation. The results identified in this review provide a starting point for future research that identifies and quantifies predictors of functional performance as factors of short, middle, and long distance running success.

The article presents the material substantiation of the regulatory effect of carbon dioxide on the maximum oxygen consumption in athletes developing endurance.The conclusion of the energy calculation formula by the values of the volumes of oxygen consumed and carbon dioxide emitted is given. Objective: on the basis of mathematical analysis and review of literature data to show the importance of the state of functional systems responsible for the removal of carbon dioxide and the need to educate athletes tolerance to hypercapnia, as one of the components in the development of endurance and physical performance. Materials and methods: the analysis is based on the literature data on sports medicine and the formula for calculating aerobic performance derived by the author. Results: the regulatory role of carbon dioxide in oxygen consumption and its importance in the synthesis of aerobic oxidation energy is shown,the article presents the material on the advantage of low-carbohydrate diets over the classic ones in the conditions of aerobic regime of physical activity. Conclusions: the role of systems responsible for the removal of carbon dioxide in the education of endurance and performance in athletes is shown, recommendations are given in the correction of nutrition and training methods for athletes developing endurance.

Background and Objective: Hookah consumption is an underlying decline in lung function. However, data are limited on the physiological effects in young trained and untrained men. The purpose of this study was to investigate the effects of chronic hookah consumption on aerobic capacity (VO2max), resting and submaximal heart rate in men who are trained and untrained. Materials and Methods: Forty-nine young men (18-34 years) were assigned into the following groups: a. trained-hookah (n = 11), b. untrained-hookah (n = 14), c. trained (n = 12) and d. untrained (n = 12). The trained men had done at least three sessions (1-hour for each) of aerobic training a week during the past three years, while the untrained men had continued a sedentary lifestyle. Hookah smokers had smoked at least three times a week during the period. The VO2max, resting and submaximal heart rate indices were measured in all subjects. Results: One-way analysis of variance showed that VO2max was significantly higher in trained group than the other groups, although no significant difference was observed in the other groups. Resting and submaximal heart rate were remarkably lower in the trained groups than in the untrained groups, but no significant difference was noted in the other groups. Conclusion: The results of the present study indicated that hookah smoking has a negative effect on aerobic capacity in men who are trained; however, it seems that the effect of aerobic training is higher than the effect of hookah on resting and submaximal heart rate indices.

Purpose: Recovery after intense interval training plays an important role in improving athletic performance, while the type of recovery and exercise background can affect athletic performance. The aim of this study was to compare the Response of blood buffering capacity to three types of recovery during Repeated High-Intensity endurance test in trained and untrained girls' students of Farhangian University. Methods: 30 female students of Farhangian University (mean age 22.49 ±.3 (year), weight 68.33 ± 7.31 (kg) and height 176.76 ± 8.32 (cm) were randomly selected in three recovery groups (active: N=10, passive: N=10, Stretching: N=10) randomly. The Subjects underwent three types of recovery during the repeated high-intensity endurance test after evaluating the maximum oxygen consumption according to a specific pattern in a crossover methods, three days in a week. Arterial blood sample were taken measured before and immediately after the test and buffering capacity and carnosine were analyzed by ABG and ELISA techniques. After 8-eight weeks of aerobic exercise (65-80% of maximal heart rate), the test and blood sampling were repeated with the same pre-test and at the same time. Results: In untrained girls, only significant difference was found between stretching and active recovery for oxygen saturation, and in trained girls' there was a significant increase in oxygen saturation for active and passive recovery. Significant increase in blood acidity, bicarbonate, base buffers and carnosine was observed in trained girls by active recovery (P ≤ 0.05). Conclusion: The results show that the response of buffering capacity to the three types of recovery was significantly higher in trained subjects. Which is more notable with active recovery. [ABSTRACT FROM AUTHOR]

The pandemic of noncommunicable diseases, which is currently one of the main threats to health and well-being of mankind, makes us look for ways to prevent their development early. Low cardiorespiratory endurance due to a sedentary lifestyle is associated with high cardiovascular risk, all-cause and cancer mortality. Skeletal muscles are the most important secretory organ and is characterized by outstanding metabolic performance and endurance. Exercise-induced low-dose stress contributes to mitochondrial biogenesis and remodeling of not only the muscular system, but also other systems involved in maintaining muscle activity, including regulating glucose and fat metabolism, maintaining immunity, and stimulating angiogenesis. These and other effects of physical activity are implements through the myokine system discovered in recent years. Shutting off the paracrine, exocrine and endocrine functions of muscles cannot be replenished in any other way and leads to disruption of vital adaptive processes. This review describes currently available evidence of unique role of aerobic physical activity in maintaining the human health, as well as to define the chain of pathological reactions during physical inactivity. The search was carried out in the Medline and PubMed Central databases for the keywords: cardiorespiratory endurance, non-communicable diseases, maximum oxygen consumption, myokines, interleukin-6, aerobic exercise.

This study investigated the associations between relative telomere length (RTL) and resting metabolic rate (RMR), resting fat oxidation (RFO), and aerobic capacity and whether oxidative stress and inflammation are the underlying mechanisms in sedentary women. We also aimed to determine whether the correlations depend on age and obesity. Sixty-eight normal weight and 66 obese women participated in this study. After adjustment for age, energy expenditure, energy intake, and education level, the RTL of all participants was negatively correlated with absolute RMR (RMRAB) and serum high-sensitivity C-reactive protein (hsCRP) concentration, and positively correlated with maximum oxygen consumption (V˙O2max) (all p < 0.05). After additional adjustment for adiposity indices and fat-free mass (FFM), RTL was positively correlated with plasma vitamin C concentration (p < 0.05). Furthermore, after adjustment for fasting blood glucose concentration, RTL was negatively correlated with age and positively correlated with V˙O2max (mL/kg FFM/min). We found that normal weight women had longer RTL than obese women (p < 0.001). We suggest that RTL is negatively correlated with RMRAB and positively correlated with aerobic capacity, possibly via antioxidant and anti-inflammatory mechanisms. Furthermore, age and obesity influenced the associations. We provide useful information for the management of promotion strategies for health-related physical fitness in women.

Background: Little information exists regarding the psychometric properties of question 8 (Q8) of the Paffenbarger Physical Activity Questionnaire (PPAQ) to assess exercise. Thus, we conducted 2 studies to assess the validity and test-retest reliability of Q8 among adults. Methods: Study 1 participants (n = 419) were 44.1 ± 16.1 years of age. Validity was determined by comparing self-reported hr ⋅ d-1 in sedentary, light, moderate, and vigorous intensity physical activity (PA) and MET-hr ⋅ wk-1 on Q8 at baseline to accelerometer and health/fitness measurements using Spearman rank-order correlations. Study 2 participants (n = 217) were 44.7 ± 16.3 years of age and completed Q8 at baseline, 3 months, and 6 months. Test-retest reliability was determined using repeated measures analysis of covariance, intraclass correlations (ICCs), and standard error of the measurement (SEM). Results: Q8 displayed good criterion validity compared with accelerometer measurements (r = .102 to .200, P < .05) and predictive validity compared with health/fitness measurements (r = -.272 to .203, P < .05). No differences were observed in self-reported hr ⋅ d-1 in any of the PA categories at baseline, 3 months, and 6 months (ICC: 0.49 to 0.68; SEM: 1.0 to 2.0; P > .05), indicating good reliability. Conclusion: Q8 demonstrates adequate criterion validity, acceptable predictive validity, and satisfactory test-retest reliability and can be used in conjunction with other components of the PPAQ to provide a complete representation of exercise. [ABSTRACT FROM AUTHOR]

Objective: To explore the cardio‐respiratory response to exercise and examine the relationships among specific measures of cardio‐respiratory function, energy expenditure (EE), fatigue and adiposity in children survivors of acute lymphoblastic leukaemia (ALL). Methods: Seventy survivors of ALL (13.31 ± 2.60 years) and 34 controls from the siblings (12.71 ± 2.36 years) participated and were assessed for submaximal and maximal exercise capacity, body composition, EE and fatigue. Results: ALL survivors had significantly lower submaximal (VO2; p = 0.002) and maximal (VO2peak; p ˂ 0.001) cardio‐respiratory capacity than their controls. At the submaximal exercise test, EE was significantly lower in ALL survivors (p < 0.001), but the heart rate (HR) was significantly higher (p = 0.005). The VO2 and HR were significantly correlated [r (95%CI) = 0.689 (0.542 to 0.795), p < 0.001]. The VO2peak negatively associated with adiposity [r (95%CI) = −0.368 (−0.554 to −0.145), p = 0.002]. Fatigue significantly correlated with the VO2peak [r (95%CI) = 0.581 (0.401 to 0.718), p < 0.001] and adiposity [r (95%CI) = −0.303 (−0.502 to 0.073), p = 0.012]. Conclusion: Children survivors of ALL experience low cardio‐respiratory fitness within 5‐year off‐chemotherapy. Associations exist between measures of cardio‐respiratory fitness, EE, fatigue and adiposity. However, it has not yet been proven whether these are cause or effect. [ABSTRACT FROM AUTHOR]

We compiled published values of mammalian maximum oxygen consumption during exercise ( ) and supplemented these data with new measurements of for the largest rodent (capybara), 20 species of smaller-bodied rodents, two species of weasels and one small marsupial. Many of the new data were obtained with running-wheel respirometers instead of the treadmill systems used in most previous measurements of mammalian . We used both conventional and phylogenetically informed allometric regression models to analyze of 77 'species' (including subspecies or separate populations within species) in relation to body size, phylogeny, diet and measurement method. Both body mass and allometrically mass-corrected showed highly significant phylogenetic signals (i.e. related species tended to resemble each other). The Akaike information criterion corrected for sample size was used to compare 27 candidate models predicting (all of which included body mass). In addition to mass, the two best-fitting models (cumulative Akaike weight=0.93) included dummy variables coding for three species previously shown to have high (pronghorn, horse and a bat), and incorporated a transformation of the phylogenetic branch lengths under an Ornstein-Uhlenbeck model of residual variation (thus indicating phylogenetic signal in the residuals). We found no statistical difference between wheel- and treadmill-elicited values, and diet had no predictive ability for . Averaged across all models, the allometric scaling exponent was 0.839, with 95% confidence limits of 0.795 and 0.883, which does not provide support for a scaling exponent of 0.67, 0.75 or unity.

Background: Preservation and storage of muscle glycogen is the most important factor limiting the success of individuals in performing the following activities. It has been shown that melatonin supplementation before exercise can maintain glycogen stores. This study aimed to investigate the effect of melatonin consumption (6 mg) on the time of exhaustion during a submaximal-activity and also the maximum oxygen consumption during an increasing activity in physical education girl students of Shahid Chamran University of Ahvaz. Materials and Methods: In this clinical trial study, 13 girls with the mean age of 21.5±1.29 years, the mean weight of 58.36±2.69 kg and vo2max 39.08±4.17 mg/kg/min were participated and received melatonin (6 mg) and placebo (starch capsules) in two complementary steps. Supplements were administered acutely 30 minutes before the exercise. Each test was repeated in placebo and supplement conditions. To ensure the elimination of exercise and supplement impact, the interval of 5 to 7 days was considered between the two tests. The sub-maximal and progressive protocols respectively included running below the maximum intensity (70% of the heart rate reserve) to exhaustion and the Bruce's test on the treadmill. Results: The results showed that consumption of 6 mg melatonin significantly increased the time to reach exhaustion (P=0.01) and the maximum oxygen consumption (P=0.002). Conclusion: It appears that trained girls can use 6 mg of melatonin supplement 30 minutes before starting the exercise to improve endurance performance and aerobic capacity.

Purpose: the identification of features of the maximum oxygen consumption of women in the first period of mature age and connection with body structure component. Material: 22-35 years old women (n=210) have participated in a research. Results. It was determined that women with endomorphic and mesomorphic somatotype prevail according to the absolute measure VO2 max. They have large body weight and higher percentage content of the muscular component. The women with low body weight and low values of fat component prevail according to a relative measure VO2 max. Large body weight in women of endomorphic, endomorphic and mesomorphic somatotype stipulates low values of a relative measure VO2 max. It is indicated by the high degree of the return correlation between a relative measure VO2 max and body weight. Conclusions. The relative measure VO2 max is considered more informative as its dependence on body weight is leveled. The obtained data indicate the advantage according to a relative measure VO2 max of women with low body weight somatotype (ectomorphic and balanced). Such feature is explained by authentically low percentage content of the fat component in women.

• Lumacaftor/ivacaftor did not improve exercise tolerance compared to placebo. • Safety results were consistent with the known lumacaftor/ivacaftor safety profile. • Future exercise tolerance studies may benefit from lessons learned from this study. The impact of lumacaftor/ivacaftor on exercise tolerance in people with cystic fibrosis (CF) has not been thoroughly studied. We conducted a multisite Phase 4 trial comparing the impact of lumacaftor/ivacaftor on exercise tolerance with that of placebo in participants ≥ 12 years of age with CF homozygous for F508del-CFTR. The primary endpoint was relative change from baseline in maximum oxygen consumption (VO 2max) during cardiopulmonary exercise testing (CPET) at Week 24. The key secondary endpoint was relative change from baseline in exercise duration during CPET at Week 24. Other secondary endpoints included changes in other indices of exercise tolerance and changes in CF assessments; safety and tolerability were assessed as an endpoint. Seventy participants were randomized to receive lumacaftor/ivacaftor (n = 34) or placebo (n = 36). The least-squares mean difference for lumacaftor/ivacaftor versus placebo in relative change in VO 2max from baseline at Week 24 was −3.2% (95% CI: −9.2, 2.9; P =0.3021); the least-squares mean difference in relative change from baseline in exercise duration at Week 24 was −3.2% (95% CI: −8.0, 1.6). Safety results were consistent with the known lumacaftor/ivacaftor safety profile. Definitive conclusions regarding the impact of lumacaftor/ivacaftor on exercise tolerance cannot be drawn from these results; however, multicenter studies using CPETs can be reliably performed with multiple time points and conventional methods, provided that calibration can be achieved. Future studies of exercise tolerance may benefit from lessons learned from this study. NCT02875366. [ABSTRACT FROM AUTHOR]

Introduction: The cancer patients are at a high risk of developing perioperative complications. Cardiopulmonary exercise testing (CPET) is a non-invasive, perioperative risk stratification tool that predicts perioperative morbidity and mortality. Prior literature has concluded that CPET has a valuable role in predicting post-operative complications in major surgical procedures. However, the data on the effectiveness of CPET in evaluating the perioperative risk in cancer-specific populations are limited. This study assessed the usefulness of CPET in perioperative risk stratification of patients with thoracoabdominal cancer who underwent elective major thoracoabdominal surgeries. Materials and Methods: A retrospective observational cohort study was conducted on cancer patients that underwent pre-operative CPET at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, from September 2017 to September 2019. All adult male and female patients with a significant medical history for cancer of the thoracoabdominal region who underwent CPET before a major thoracoabdominal surgery were included in the study. Results: A total of 32 patients were included in the present investigation. The mean age of the sample was 62.75 ± 10.18 years, and the majority of the participants were female. Following surgery, 53% of the participants had post-operative complications in terms of morbidity and mortality. Fifteen participants had an anaerobic threshold (AT) of ≥11.0 ml/ kg/min. Among these, 12 participants had an uneventful surgery. On the contrary, among 17 participants that were considered to have a high risk (

Supplemental digital content is available in the text. Equations are often used to predict cardiorespiratory fitness (CRF) from submaximal or maximal exercise tests. However, no study has comprehensively compared these exercise-based equations with directly measured CRF using data from a single, large cohort. Purpose: This study aimed to compare the accuracy of exercise-based prediction equations with directly measured CRF and evaluate their ability to classify an individual's CRF. Methods: The sample included 4871 tests from apparently healthy adults (38% female, age 44.4 ± 12.3 yr (mean ± SD)). Estimated CRF (eCRF) was determined from 2 nonexercise equations, 3 submaximal exercise equations, and 10 maximal exercise equations; all eCRF calculations were then compared with directly measured CRF, determined from a cardiopulmonary exercise test. Analysis included Pearson product–moment correlations, standard error of estimate values, intraclass correlation coefficients, Cohen κ coefficients, and the Benjamini–Hochberg procedure to compare eCRF with directly measured CRF. Results: All eCRF values from the prediction equations were associated with directly measured CRF (P < 0.01), with intraclass correlation coefficient estimates ranging from 0.07 to 0.89. Although significant agreement was found when using eCRF to categorize participants into fitness tertiles, submaximal exercise equations correctly classified an average of only 51% (range, 37%–58%) and maximal exercise equations correctly classified an average of only 59% (range, 43%–76%). Conclusions: Despite significant associations between exercise-based prediction equations and directly measured CRF, the equations had a low degree of accuracy in categorizing participants into fitness tertiles, a key requirement when stratifying risk within a clinical setting. The present analysis highlights the limited accuracy of exercise-based determinations of eCRF and suggests the need to include cardiopulmonary measures with maximal exercise to accurately assess CRF within a clinical setting. [ABSTRACT FROM AUTHOR]

BACKGROUND: Neuromuscular electrical stimulation (NMES) is a complementary tool for therapeutic exercise for muscle strengthening and may potentially enhance exercise performance. OBJECTIVE: To determine whether high-intensity interval training (HIIT) and continuous aerobic training (CA) coupled with NMES enhance the changes in the eccentric/concentric muscle contraction patterns of hamstring and quadriceps. METHODS: Forty-five healthy sedentary male participants performed cycling training 3 times per week for 8 weeks combined with/without NMES performed at a load equivalent to 65% and 120% of I VO 2max (intensity associated with the achievement of maximal oxygen uptake). Anthropometrics, blood lactate measurements, I VO 2max , T Lim VO 2max (time-to-exhaustion) and isokinetic strength parameters were measured at baseline and post-training using a randomized controlled trial. RESULTS: The conventional hamstring-to-quadriceps-ratio (HQR: Hcon/Qcon) at 60 ∘ /s and the Dynamic Control Ratio (DCR: Hecc/Qcon) at 180 ∘ /s significantly increased both in the dominant (D) and non-dominant (ND) limb in the HIIT + NMES group (p < 0.05). There was a positive significant correlation between the individual changes in D HQR at 60 ∘ /s and I VO 2max (r = 0.94, p = 0.005) and the DCR at 180 ∘ /s and T Lim VO 2max (r = 0.90, p = 0.015), respectively. CONCLUSIONS: The increases in the eccentric muscle contraction and DCR following HIIT + NMES seem to improve fatigue tolerance, cause less fatigue and oxidative stress on the lower limb during pedaling at high intensities. [ABSTRACT FROM AUTHOR]

Copyright of SportLogia is the property of University Banja Luka, Faculty of Physical Education & Sports and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background Repeated assessment of cardiorespiratory fitness (CRF) improves mortality risk predictions in apparently healthy adults. Accordingly, the American Heart Association suggests routine clinical assessment of CRF using, at a minimum, nonexercise prediction equations. However, the accuracy of nonexercise prediction equations over time is unknown. Therefore, we compared the ability of nonexercise prediction equations to detect changes in directly measured CRF. Methods and Results The sample included 987 apparently healthy adults from the BALL ST (Ball State Adult Fitness Longitudinal Lifestyle Study) cohort (33% women; average age, 43.1±10.4 years) who completed 2 cardiopulmonary exercise tests ≥3 months apart (3.2±5.4 years of follow‐up). The change in estimated CRF (eCRF) from 27 distinct nonexercise prediction equations was compared with the change in directly measured CRF. Analysis included Pearson product moment correlations, SEE values, intraclass correlation coefficient values, Cohen's κ coefficients, γ coefficients, and the Benjamini‐Hochberg procedure to compare eCRF with directly measured CRF. The change in eCRF from 26 of 27 equations was significantly associated to the change in directly measured CRF (P

Background and aims: Body anthropometric dimensions are among the factors affecting the maximum oxygen consumption. This study aimed to predict maximum oxygen consumption based on anthropometric dimensions in medical emergency students. Methods: This cross-sectional analytical study was conducted among 56 medical emergency students from Qazvin University of medical sciences. Initially, physical activity readiness Questionnaire (PAR-Q) was applied to ensure the full health of participants to inter the study. Maximum oxygen consumption measured using Gerkin treadmill test. Anthropometric dimensions were measured by tape measure, anthropometer and kolis. Obtain data was analyzed by Pearson product moment correlation and multiple linear regressions in SPSS 19 software. Results: The mean age of participants was 21.69 years. The mean of maximum oxygen consumption and mean of foot length estimated 4.17 L/min and 96.35 cm, respectively. There was significant correlation between the maximum oxygen with the anthropometric dimensions. Variables of dimensions of abdomen circumstance, foot length and leg circumstance predicted 63.7 percent of the maximum oxygen consumption. Conclusion: The results indicated that the anthropometric dimensions are the factors affecting the maximum oxygen consumption among medical emergency student. So, it is necessary to be paid attention to anthropometric dimension in selection of students and matching between person capabilities with energy.

Compare single-leg aerobic capacity and strength differences between the surgically repaired ACL leg (injured) and the uninjured leg. Cross-sectional study. Laboratory. Eight participants (5 female, 3 male, age = 23 ± 3.5 y, mass = 72.3 ± 17.3 kg, height = 169.7 ± 9.4 cm) that returned to play from ACL surgery between six and 18 months. Participants performed an aerobically-based, single-leg cycling protocol to determine maximum oxygen consumption, ventilatory threshold, heart rate, rating of perceived exertion, and maximal watts cycled. Participants also performed isokinetic knee flexion and extension on a dynamometer to assess peak torque, total work, work fatigue, and power. There were no statistical differences in single-leg aerobic capacity or strength outcomes between the injured and uninjured legs. Individuals who have had an ACL surgically repaired six to 18 months after return to play do not appear to have aerobic capacity or strength deficits between the injured leg and uninjured leg. • To our knowledge, single-leg aerobic capacity has yet to be investigated in a surgically repaired ACL population. • There were no differences in single-leg aerobic capacity/ strength outcomes in individuals with surgically repaired ACLs. • More research is necessary to determine the role single-leg aerobic capacity could play in rehabilitation/return to play. [ABSTRACT FROM AUTHOR]

The purpose of this research was to determine if respiratory muscle (RM) training, through the MRFit protocol, increases the maximum oxygen consumption and the anaerobic threshold in a group of young professional swimmers, to improve their sports performance. Eleven professional swimmers (7 women and 4 men) between 13 and 17 years old were recruited in this study. Participants were randomly assigned into two groups: control (CG) and training (TG). TG received RM training (MRFit) 20 minutes, two times a week for eight weeks incorporated into their usual training, while the CG only continued their usual training. All the participants performed, before and after the training, ergospirometric tests on a treadmill, to compare the results at the end of the eight weeks. Subsequently, a parametric statistical analysis was performed via a t-test. No significant differences were found for VO2max between CG and TG nor for the anaerobic threshold (p>0.05). Despite the non-significant results, we have determined different tendencies between both groups and clinical improvements. [ABSTRACT FROM AUTHOR]