1. Broadband Reduction of the Second Harmonic Distortion During Nonlinear Ultrasound Wave Propagation
- Author
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Mike Danilouchkine, Olivier Basset, Christian Cachard, Nico de Jong, Guillaume Matte, Mirza Pasovic, Antonius F.W. van der Steen, Imagerie Ultrasonore, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche et d'Application en Traitement de l'Image et du Signal (CREATIS), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Cardiothoracic Surgery, and Cardiology
- Subjects
Acoustics and Ultrasonics ,Acoustics ,Transducers ,Physics::Medical Physics ,Biophysics ,Phase (waves) ,Contrast Media ,imagerie_ultrasonore ,Optics ,categₛt2i ,[INFO.INFO-IM]Computer Science [cs]/Medical Imaging ,Waveform ,Radiology, Nuclear Medicine and imaging ,ComputingMilieux_MISCELLANEOUS ,Ultrasonography ,Physics ,Total harmonic distortion ,Microbubbles ,Radiological and Ultrasound Technology ,Phantoms, Imaging ,business.industry ,Signal Processing, Computer-Assisted ,Image Enhancement ,Imagerie Ultrasonore ,reseau_international ,Nonlinear distortion ,Harmonics ,Discrete frequency domain ,Harmonic ,Imaging Signal ,business - Abstract
Ultrasound contrast harmonic imaging and detection techniques are hampered by the harmonic distortion of the ultrasound wave caused by the nonlinearities of the medium. To increase the discrimination between the tissue and ultrasound contrast agents at higher harmonics, we investigate a tissue harmonic suppression technique. The main attention of the research is the signal that is introduced at the source and is constructed out of several discrete frequency components from the second harmonic band. Therefore, this method was coined as the multiple component second harmonic reduction signal or multiple component SHRS. By adjusting the amplitude and phase of discrete components and simultaneously propagating multiple component SHRS with the imaging signal, the nonlinear distortion of the ultrasound waveform is considerably reduced. Using the numerical simulation, the optimal parameters for multiple component SRHS were deduced. The simulations results were corroborated in the water tank experiments and showed 40 dB reduction with respect to the fundamental, covering up to 75% of the entire second harmonic band. In the other series of experiments with the clinically used contrast agent, the uniform increase in agent-to-tissue ratio of 7.4 dB over a relatively large region of imaging was observed. The use of the proposed method in the everyday clinical practice can improve discrimination between the tissue and the contrast agent in harmonic imaging. ( E-mail: mirza.pasovic@creatis.insa-lyon.fr) (C) 2010 World Federation for Ultrasound in Medicine & Biology.
- Published
- 2010
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