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Longitudinal displacement of the carotid wall and cardiovascular risk factors: associations with aging, adiposity, blood pressure and periodontal disease independent of cross-sectional distensibility and intima-media thickness
- Source :
- Ultrasound in Medicine & Biology, Ultrasound in Medicine & Biology, Elsevier, 2012, 38 (10), pp.1705-1715. ⟨10.1016/j.ultrasmedbio.2012.05.004⟩, Ultrasound in Medicine & Biology, 2012, 38 (10), pp.1705-1715. ⟨10.1016/j.ultrasmedbio.2012.05.004⟩
- Publication Year :
- 2012
- Publisher :
- US : Elsevier, 2012.
-
Abstract
- The recently discovered longitudinal displacement of the common carotid arterial wall (i.e., the motion along the same plane as the blood flow), may be associated with incident cardiovascular events and represents a novel and relevant clinical information. At present, there have only been a few studies that have been conducted to investigate this longitudinal movement. We propose here a method to assess noninvasively the wall bi-dimensional (two-dimensional [2-D], cross-sectional and longitudinal) motion and present an original approach that combines a robust speckle tracking scheme to guidance by minimal path contours segmentation. Our method is well suited to large clinical population studies as it does not necessitate strong imaging prerequisites. The aim of this study is to describe the association between the longitudinal displacement of the carotid arterial wall and cardiovascular risk factors, among which periodontal disease. Some 126 Indigenous Australians with periodontal disease, an emerging risk factor, and 27 healthy age- and sex-matched non-indigenous control subjects had high-resolution ultrasound scans of the common carotid artery. Carotid intima-media thickness and arterial wall 2-D motion were then assessed using our method in ultrasound B-mode sequences. Carotid longitudinal displacement was markedly lower in the periodontal disease group than the control group (geometric mean (IQR): 0.15 mm (0.13) vs. 0.42 mm (0.30), respectively; p < 0.0001), independent of cardiovascular risk factors, cross-sectional distensibility and carotid intima-media thickness (p < 0.0001). A multivariable model indicated that the strongest correlates of carotid longitudinal displacement in adults with periodontal disease were age (β-coefficient = -.235, p = .03), waist (β-coefficient = -.357, p = 0.001), and pulse pressure (β-coefficient = .175, p = 0.07), independent of other cardiovascular risk factors, cross-sectional distensibility and pulse wave velocity. Carotid longitudinal displacement, estimated with our approach, is impaired in the periodontal disease group, independent of established cardiovascular risk factors and other noninvasive measures of arterial stiffness, and may represent an important marker of cardiovascular risk. Refereed/Peer-reviewed
- Subjects :
- Male
cardiovascular risk factors
Aging
Longitudinal study
Acoustics and Ultrasonics
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging
Labex CELYA
periodontal disease
Blood Pressure
Comorbidity
030204 cardiovascular system & hematology
Carotid Intima-Media Thickness
Labex PRIMES
030218 nuclear medicine & medical imaging
motion estimation
0302 clinical medicine
Risk Factors
Carotid artery disease
Prevalence
Common carotid artery
Pulse wave velocity
ComputingMilieux_MISCELLANEOUS
Adiposity
education.field_of_study
Radiological and Ultrasound Technology
Middle Aged
3. Good health
Imagerie Ultrasonore
reseau_international
Carotid Arteries
arterial stiffness
speckle tracking
Cardiovascular Diseases
Female
categₘixte
Radiology
[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
Adult
medicine.medical_specialty
Population
Biophysics
imagerie_ultrasonore
Risk Assessment
03 medical and health sciences
Age Distribution
Elastic Modulus
medicine.artery
reseau_internationnal
medicine
Humans
Radiology, Nuclear Medicine and imaging
education
Periodontal Diseases
longitudinal displacement
[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]
business.industry
carotid artery
segmentation
Australia
Australie
medicine.disease
Blood pressure
Intima-media thickness
b-mode ultrasound
Arterial stiffness
Vascular Resistance
atherosclerosis
business
Subjects
Details
- Language :
- English
- ISSN :
- 03015629
- Database :
- OpenAIRE
- Journal :
- Ultrasound in Medicine & Biology, Ultrasound in Medicine & Biology, Elsevier, 2012, 38 (10), pp.1705-1715. ⟨10.1016/j.ultrasmedbio.2012.05.004⟩, Ultrasound in Medicine & Biology, 2012, 38 (10), pp.1705-1715. ⟨10.1016/j.ultrasmedbio.2012.05.004⟩
- Accession number :
- edsair.doi.dedup.....84c94d208571678d693524278c68a2f3