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Optimizacija procesa komisioniranja je eden ključnih logističnih procesov, ki pomenijo ločnico med finančno učinkovitostjo in neučinkovitostjo. Klasična podpora s strani integriranih informacijskih sistemov zagotavlja potrebno podporo, a sama po sebi ne zadošča, zato se kot podpora le-temu v praksi pogosto pojavljajo različne podporne metode, ki se izvajajo ročno v svoji delni obliki. Kontrolno tehtanje predstavlja le enega izmed načinov, kako se približati popolnim rezultatom optimizacije sistema komisioniranja blaga ter posledično finančni konsolidaciji in stroškovni optimizaciji pri poslovanju skladišč. Ključ uspešnosti ni inovativnost oziroma tehnološka kompleksnost, ampak vsestranska aplikativnost takšnega sistema pri ravnanju z objekti, ki so medsebojno vizualno in strukturno povsem različni. V teoretičnem delu diplomskega dela so podana izhodišča za razumevanje procesa komisioniranja ter njegove tesne povezave z informacijskimi sistemi in predstavljeni pojmi, ki se pojavljajo v praktičnem delu diplomskega dela. V le-tem je podrobneje predstavljeno komisioniranje znotraj podjetja ter problemi, ki se pojavljajo. V zaključku dela so podane rešitve in projecirani možni učinki, ki bi jih imela njihova vpeljava. Picking process optimization is one of the key elements that represent the boundary between financial success or failure. Standard support by use of integrated information systems ensures the required support but it does not suffice. As a result, different support methods are commonly used in practice and are carried out manually in their partial form. Weight control represents only one way of achieving the perfect results of picking process optimization and consequencally achievement of financial consolidation and costs optimization in warehouse management. The key to success is neither inovation nor tehnological complexity but rather the aplicable value of such systems in handling objects that are visually and structurally different. In the theoretical part of this diploma work the basics are given for better understanding of a picking process and its tight connection to information systems. In the practical part, both the picking process and the problems which are occuring inside the company are explained in detail. The conclusion of diploma work contains possible solutions and projections of expected effects, which would be caused by their implementation.