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3 results on '"dose spillage"'

1. Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience

Author

Narendra Kumar, Srinivasa GY, Chinna B Dracham, Treshita Dey, Renu Madan, Divya Khosla, Arun Oinum, and Rakesh Kapoor

Subjects
3D-conformal radiotherapy (3D-CRT), adjuvant TMZ, cochlea, concurrent temozolomide (TMZ), conformity index, dose spillage, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials & Methods: All patients received concurrent temozolomide every day, and this was followed by adjuvant temozolomide of 5 days of treatment per month. Results: More than 98% of patients were treated with a dose of 60 Gy. Doses were analyzed for the normal whole brain, tumor volume, as well as all the organs at risk. Conclusion: Given the grave prognosis and the limited survival of glioblastoma despite the best treatment available, makes 3D-conformal radiotherapy an equally acceptable treatment option.

Published
2020
Full Text
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2. Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience

Author

Divya Khosla, Renu Madan, Rakesh Kapoor, Chinna Babu Dracham, Arun Oinum, G. Y. Srinivasa, Narendra Kumar, and Treshita Dey

Subjects
Male, Organs at Risk, medicine.medical_specialty, medicine.medical_treatment, 3D-conformal radiotherapy (3D-CRT), cochlea, Planning target volume, dosimetric analysis, Dose distribution, concurrent temozolomide (TMZ), Tertiary Care Centers, medicine, Temozolomide, Humans, Antineoplastic Agents, Alkylating, Retrospective Studies, adjuvant TMZ, business.industry, Brain Neoplasms, dose spillage, Radiotherapy Planning, Computer-Assisted, optic chiasm, postoperative glioblastoma (GBM), Cancer, Radiotherapy Dosage, General Medicine, Chemoradiotherapy, Middle Aged, conformity index, medicine.disease, Prognosis, homogeneity index, Radiation therapy, Total dose, Female, Radiology, Radiotherapy, Intensity-Modulated, Radiotherapy, Conformal, business, Glioblastoma, Adjuvant, medicine.drug, Research Article
Abstract

Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials & Methods: All patients received concurrent temozolomide every day, and this was followed by adjuvant temozolomide of 5 days of treatment per month. Results: More than 98% of patients were treated with a dose of 60 Gy. Doses were analyzed for the normal whole brain, tumor volume, as well as all the organs at risk. Conclusion: Given the grave prognosis and the limited survival of glioblastoma despite the best treatment available, makes 3D-conformal radiotherapy an equally acceptable treatment option.

Published
2020

3. Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience.

Author

Kumar N, Gy S, Dracham CB, Dey T, Madan R, Khosla D, Oinum A, and Kapoor R

Subjects
Antineoplastic Agents, Alkylating therapeutic use, Brain Neoplasms diagnostic imaging, Brain Neoplasms drug therapy, Brain Neoplasms pathology, Chemoradiotherapy, Female, Glioblastoma diagnostic imaging, Glioblastoma drug therapy, Glioblastoma pathology, Humans, Male, Middle Aged, Organs at Risk diagnostic imaging, Prognosis, Radiotherapy Dosage, Radiotherapy, Conformal, Radiotherapy, Intensity-Modulated, Retrospective Studies, Temozolomide therapeutic use, Tertiary Care Centers, Brain Neoplasms radiotherapy, Glioblastoma radiotherapy, Organs at Risk radiation effects, Radiotherapy Planning, Computer-Assisted methods
Abstract

Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials &   Methods: All patients received concurrent temozolomide every day, and this was followed by adjuvant temozolomide of 5 days of treatment per month. Results: More than 98% of patients were treated with a dose of 60 Gy. Doses were analyzed for the normal whole brain, tumor volume, as well as all the organs at risk. Conclusion: Given the grave prognosis and the limited survival of glioblastoma despite the best treatment available, makes 3D-conformal radiotherapy an equally acceptable treatment option.

Published
2020
Full Text
View/download PDF

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