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Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience
- Source :
- CNS Oncology
- Publication Year :
- 2020
-
Abstract
- Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials & Methods: All patients received concurrent temozolomide every day, and this was followed by adjuvant temozolomide of 5 days of treatment per month. Results: More than 98% of patients were treated with a dose of 60 Gy. Doses were analyzed for the normal whole brain, tumor volume, as well as all the organs at risk. Conclusion: Given the grave prognosis and the limited survival of glioblastoma despite the best treatment available, makes 3D-conformal radiotherapy an equally acceptable treatment option.
- Subjects :
- Male
Organs at Risk
medicine.medical_specialty
medicine.medical_treatment
3D-conformal radiotherapy (3D-CRT)
cochlea
Planning target volume
dosimetric analysis
Dose distribution
concurrent temozolomide (TMZ)
Tertiary Care Centers
medicine
Temozolomide
Humans
Antineoplastic Agents, Alkylating
Retrospective Studies
adjuvant TMZ
business.industry
Brain Neoplasms
dose spillage
Radiotherapy Planning, Computer-Assisted
optic chiasm
postoperative glioblastoma (GBM)
Cancer
Radiotherapy Dosage
General Medicine
Chemoradiotherapy
Middle Aged
conformity index
medicine.disease
Prognosis
homogeneity index
Radiation therapy
Total dose
Female
Radiology
Radiotherapy, Intensity-Modulated
Radiotherapy, Conformal
business
Glioblastoma
Adjuvant
medicine.drug
Research Article
Subjects
Details
- ISSN :
- 20450915
- Volume :
- 9
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- CNS oncology
- Accession number :
- edsair.doi.dedup.....b743dcecd2233a2a5296449276c5bb65